-
2
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
T.M. Teslovich, K. Musunuru, A.V. Smith, A.C. Edmondson, I.M. Stylianou, M. Koseki, J.P. Pirruccello, S. Ripatti, D.I. Chasman, C.J. Willer, and et al. Biological, clinical and population relevance of 95 loci for blood lipids Nature 466 2010 707 713
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
Musunuru, K.2
Smith, A.V.3
Edmondson, A.C.4
Stylianou, I.M.5
Koseki, M.6
Pirruccello, J.P.7
Ripatti, S.8
Chasman, D.I.9
Willer, C.J.10
-
3
-
-
79959835081
-
Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study
-
L. Dumitrescu, C.L. Carty, K. Taylor, F.R. Schumacher, L.A. Hindorff, J.L. Ambite, G. Anderson, L.G. Best, K. Brown-Gentry, P. Bůžková, and et al. Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study PLoS Genet. 7 2011 e1002138
-
(2011)
PLoS Genet.
, vol.7
, pp. e1002138
-
-
Dumitrescu, L.1
Carty, C.L.2
Taylor, K.3
Schumacher, F.R.4
Hindorff, L.A.5
Ambite, J.L.6
Anderson, G.7
Best, L.G.8
Brown-Gentry, K.9
Bůžková, P.10
-
4
-
-
84887099827
-
Discovery and refinement of loci associated with lipid levels
-
C.J. Willer, E.M. Schmidt, S. Sengupta, G.M. Peloso, S. Gustafsson, S. Kanoni, A. Ganna, J. Chen, M.L. Buchkovich, S. Mora, et al. Global Lipids Genetics Consortium Discovery and refinement of loci associated with lipid levels Nat. Genet. 45 2013 1274 1283
-
(2013)
Nat. Genet.
, vol.45
, pp. 1274-1283
-
-
Willer, C.J.1
Schmidt, E.M.2
Sengupta, S.3
Peloso, G.M.4
Gustafsson, S.5
Kanoni, S.6
Ganna, A.7
Chen, J.8
Buchkovich, M.L.9
Mora, S.10
-
5
-
-
84878849984
-
Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci
-
D. Weissglas-Volkov, C.A. Aguilar-Salinas, E. Nikkola, K.A. Deere, I. Cruz-Bautista, O. Arellano-Campos, L.L. Muñoz-Hernandez, L. Gomez-Munguia, M.L. Ordoñez-Sánchez, P.M. Reddy, and et al. Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci J. Med. Genet. 50 2013 298 308
-
(2013)
J. Med. Genet.
, vol.50
, pp. 298-308
-
-
Weissglas-Volkov, D.1
Aguilar-Salinas, C.A.2
Nikkola, E.3
Deere, K.A.4
Cruz-Bautista, I.5
Arellano-Campos, O.6
Muñoz-Hernandez, L.L.7
Gomez-Munguia, L.8
Ordoñez-Sánchez, M.L.9
Reddy, P.M.10
-
6
-
-
38649125868
-
Newly identified loci that influence lipid concentrations and risk of coronary artery disease
-
C.J. Willer, S. Sanna, A.U. Jackson, A. Scuteri, L.L. Bonnycastle, R. Clarke, S.C. Heath, N.J. Timpson, S.S. Najjar, H.M. Stringham, and et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease Nat. Genet. 40 2008 161 169
-
(2008)
Nat. Genet.
, vol.40
, pp. 161-169
-
-
Willer, C.J.1
Sanna, S.2
Jackson, A.U.3
Scuteri, A.4
Bonnycastle, L.L.5
Clarke, R.6
Heath, S.C.7
Timpson, N.J.8
Najjar, S.S.9
Stringham, H.M.10
-
7
-
-
38649132270
-
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
-
S. Kathiresan, O. Melander, C. Guiducci, A. Surti, N.P. Burtt, M.J. Rieder, G.M. Cooper, C. Roos, B.F. Voight, A.S. Havulinna, and et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans Nat. Genet. 40 2008 189 197
-
(2008)
Nat. Genet.
, vol.40
, pp. 189-197
-
-
Kathiresan, S.1
Melander, O.2
Guiducci, C.3
Surti, A.4
Burtt, N.P.5
Rieder, M.J.6
Cooper, G.M.7
Roos, C.8
Voight, B.F.9
Havulinna, A.S.10
-
8
-
-
67449128717
-
Large scale replication analysis of loci associated with lipid concentrations in a Japanese population
-
K. Nakayama, T. Bayasgalan, K. Yamanaka, M. Kumada, T. Gotoh, N. Utsumi, Y. Yanagisawa, M. Okayama, E. Kajii, S. Ishibashi, S. Iwamoto Jichi Community Genetics Team (JCOG) Large scale replication analysis of loci associated with lipid concentrations in a Japanese population J. Med. Genet. 46 2009 370 374
-
(2009)
J. Med. Genet.
, vol.46
, pp. 370-374
-
-
Nakayama, K.1
Bayasgalan, T.2
Yamanaka, K.3
Kumada, M.4
Gotoh, T.5
Utsumi, N.6
Yanagisawa, Y.7
Okayama, M.8
Kajii, E.9
Ishibashi, S.10
Iwamoto, S.11
-
9
-
-
77952533413
-
Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples
-
D. Weissglas-Volkov, C.A. Aguilar-Salinas, J.S. Sinsheimer, L. Riba, A. Huertas-Vazquez, M.L. Ordoñez-Sánchez, R. Rodriguez-Guillen, R.M. Cantor, T. Tusie-Luna, and P. Pajukanta Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples Circ Cardiovasc Genet 3 2010 31 38
-
(2010)
Circ Cardiovasc Genet
, vol.3
, pp. 31-38
-
-
Weissglas-Volkov, D.1
Aguilar-Salinas, C.A.2
Sinsheimer, J.S.3
Riba, L.4
Huertas-Vazquez, A.5
Ordoñez-Sánchez, M.L.6
Rodriguez-Guillen, R.7
Cantor, R.M.8
Tusie-Luna, T.9
Pajukanta, P.10
-
10
-
-
58149163149
-
Common variants at 30 loci contribute to polygenic dyslipidemia
-
S. Kathiresan, C.J. Willer, G.M. Peloso, S. Demissie, K. Musunuru, E.E. Schadt, L. Kaplan, D. Bennett, Y. Li, T. Tanaka, and et al. Common variants at 30 loci contribute to polygenic dyslipidemia Nat. Genet. 41 2009 56 65
-
(2009)
Nat. Genet.
, vol.41
, pp. 56-65
-
-
Kathiresan, S.1
Willer, C.J.2
Peloso, G.M.3
Demissie, S.4
Musunuru, K.5
Schadt, E.E.6
Kaplan, L.7
Bennett, D.8
Li, Y.9
Tanaka, T.10
-
11
-
-
84975795680
-
An integrated map of genetic variation from 1,092 human genomes
-
G.R. Abecasis, A. Auton, L.D. Brooks, M.A. DePristo, R.M. Durbin, R.E. Handsaker, H.M. Kang, G.T. Marth, G.A. McVean 1000 Genomes Project Consortium An integrated map of genetic variation from 1,092 human genomes Nature 491 2012 56 65
-
(2012)
Nature
, vol.491
, pp. 56-65
-
-
Abecasis, G.R.1
Auton, A.2
Brooks, L.D.3
DePristo, M.A.4
Durbin, R.M.5
Handsaker, R.E.6
Kang, H.M.7
Marth, G.T.8
McVean, G.A.9
-
12
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
ENCODE Project Consortium An integrated encyclopedia of DNA elements in the human genome Nature 489 2012 57 74
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
-
13
-
-
84923362619
-
Integrative analysis of 111 reference human epigenomes
-
A. Kundaje, W. Meuleman, J. Ernst, M. Bilenky, A. Yen, A. Heravi-Moussavi, P. Kheradpour, Z. Zhang, J. Wang, M.J. Ziller, et al. Roadmap Epigenomics Consortium Integrative analysis of 111 reference human epigenomes Nature 518 2015 317 330
-
(2015)
Nature
, vol.518
, pp. 317-330
-
-
Kundaje, A.1
Meuleman, W.2
Ernst, J.3
Bilenky, M.4
Yen, A.5
Heravi-Moussavi, A.6
Kheradpour, P.7
Zhang, Z.8
Wang, J.9
Ziller, M.J.10
-
15
-
-
84880920122
-
Bringing genome-wide association findings into clinical use
-
T.A. Manolio Bringing genome-wide association findings into clinical use Nat. Rev. Genet. 14 2013 549 558
-
(2013)
Nat. Rev. Genet.
, vol.14
, pp. 549-558
-
-
Manolio, T.A.1
-
16
-
-
0037234565
-
All in the family: The UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases
-
K.G. Ten Hagen, T.A. Fritz, and L.A. Tabak All in the family: the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases Glycobiology 13 2003 1R 16R
-
(2003)
Glycobiology
, vol.13
, pp. 1R-16R
-
-
Ten Hagen, K.G.1
Fritz, T.A.2
Tabak, L.A.3
-
17
-
-
0028803582
-
Purification and cDNA cloning of a human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase
-
T. White, E.P. Bennett, K. Takio, T. Sørensen, N. Bonding, and H. Clausen Purification and cDNA cloning of a human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase J. Biol. Chem. 270 1995 24156 24165
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 24156-24165
-
-
White, T.1
Bennett, E.P.2
Takio, K.3
Sørensen, T.4
Bonding, N.5
Clausen, H.6
-
18
-
-
0030035111
-
CDNA cloning and expression of a novel human UDP-N-acetyl-alpha-D-galactosamine. Polypeptide N-acetylgalactosaminyltransferase, GalNAc-t3
-
E.P. Bennett, H. Hassan, and H. Clausen cDNA cloning and expression of a novel human UDP-N-acetyl-alpha-D-galactosamine. Polypeptide N-acetylgalactosaminyltransferase, GalNAc-t3 J. Biol. Chem. 271 1996 17006 17012
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17006-17012
-
-
Bennett, E.P.1
Hassan, H.2
Clausen, H.3
-
19
-
-
84860365843
-
Control of mucin-type O-glycosylation: A classification of the polypeptide GalNAc-transferase gene family
-
E.P. Bennett, U. Mandel, H. Clausen, T.A. Gerken, T.A. Fritz, and L.A. Tabak Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family Glycobiology 22 2012 736 756
-
(2012)
Glycobiology
, vol.22
, pp. 736-756
-
-
Bennett, E.P.1
Mandel, U.2
Clausen, H.3
Gerken, T.A.4
Fritz, T.A.5
Tabak, L.A.6
-
20
-
-
78449258533
-
O-glycosylation modulates proprotein convertase activation of angiopoietin-like protein 3: Possible role of polypeptide GalNAc-transferase-2 in regulation of concentrations of plasma lipids
-
K.T. Schjoldager, M.B. Vester-Christensen, E.P. Bennett, S.B. Levery, T. Schwientek, W. Yin, O. Blixt, and H. Clausen O-glycosylation modulates proprotein convertase activation of angiopoietin-like protein 3: possible role of polypeptide GalNAc-transferase-2 in regulation of concentrations of plasma lipids J. Biol. Chem. 285 2010 36293 36303
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 36293-36303
-
-
Schjoldager, K.T.1
Vester-Christensen, M.B.2
Bennett, E.P.3
Levery, S.B.4
Schwientek, T.5
Yin, W.6
Blixt, O.7
Clausen, H.8
-
21
-
-
82955239839
-
Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man
-
A.G. Holleboom, H. Karlsson, R.S. Lin, T.M. Beres, J.A. Sierts, D.S. Herman, E.S. Stroes, J.M. Aerts, J.J. Kastelein, M.M. Motazacker, and et al. Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man Cell Metab. 14 2011 811 818
-
(2011)
Cell Metab.
, vol.14
, pp. 811-818
-
-
Holleboom, A.G.1
Karlsson, H.2
Lin, R.S.3
Beres, T.M.4
Sierts, J.A.5
Herman, D.S.6
Stroes, E.S.7
Aerts, J.M.8
Kastelein, J.J.9
Motazacker, M.M.10
-
22
-
-
65549163338
-
Changes in insulin sensitivity and insulin release in relation to glycemia and glucose tolerance in 6,414 Finnish men
-
A. Stancáková, M. Javorský, T. Kuulasmaa, S.M. Haffner, J. Kuusisto, and M. Laakso Changes in insulin sensitivity and insulin release in relation to glycemia and glucose tolerance in 6,414 Finnish men Diabetes 58 2009 1212 1221
-
(2009)
Diabetes
, vol.58
, pp. 1212-1221
-
-
Stancáková, A.1
Javorský, M.2
Kuulasmaa, T.3
Haffner, S.M.4
Kuusisto, J.5
Laakso, M.6
-
23
-
-
79955583542
-
Mapping and analysis of chromatin state dynamics in nine human cell types
-
J. Ernst, P. Kheradpour, T.S. Mikkelsen, N. Shoresh, L.D. Ward, C.B. Epstein, X. Zhang, L. Wang, R. Issner, M. Coyne, and et al. Mapping and analysis of chromatin state dynamics in nine human cell types Nature 473 2011 43 49
-
(2011)
Nature
, vol.473
, pp. 43-49
-
-
Ernst, J.1
Kheradpour, P.2
Mikkelsen, T.S.3
Shoresh, N.4
Ward, L.D.5
Epstein, C.B.6
Zhang, X.7
Wang, L.8
Issner, R.9
Coyne, M.10
-
24
-
-
84873085571
-
Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion
-
J.R. Huyghe, A.U. Jackson, M.P. Fogarty, M.L. Buchkovich, A. Stančáková, H.M. Stringham, X. Sim, L. Yang, C. Fuchsberger, H. Cederberg, and et al. Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion Nat. Genet. 45 2013 197 201
-
(2013)
Nat. Genet.
, vol.45
, pp. 197-201
-
-
Huyghe, J.R.1
Jackson, A.U.2
Fogarty, M.P.3
Buchkovich, M.L.4
Stančáková, A.5
Stringham, H.M.6
Sim, X.7
Yang, L.8
Fuchsberger, C.9
Cederberg, H.10
-
25
-
-
84868490540
-
Detecting and estimating contamination of human DNA samples in sequencing and array-based genotype data
-
G. Jun, M. Flickinger, K.N. Hetrick, J.M. Romm, K.F. Doheny, G.R. Abecasis, M. Boehnke, and H.M. Kang Detecting and estimating contamination of human DNA samples in sequencing and array-based genotype data Am. J. Hum. Genet. 91 2012 839 848
-
(2012)
Am. J. Hum. Genet.
, vol.91
, pp. 839-848
-
-
Jun, G.1
Flickinger, M.2
Hetrick, K.N.3
Romm, J.M.4
Doheny, K.F.5
Abecasis, G.R.6
Boehnke, M.7
Kang, H.M.8
-
26
-
-
84871952176
-
Improved whole-chromosome phasing for disease and population genetic studies
-
O. Delaneau, J.F. Zagury, and J. Marchini Improved whole-chromosome phasing for disease and population genetic studies Nat. Methods 10 2013 5 6
-
(2013)
Nat. Methods
, vol.10
, pp. 5-6
-
-
Delaneau, O.1
Zagury, J.F.2
Marchini, J.3
-
27
-
-
84864417548
-
Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
-
B. Howie, C. Fuchsberger, M. Stephens, J. Marchini, and G.R. Abecasis Fast and accurate genotype imputation in genome-wide association studies through pre-phasing Nat. Genet. 44 2012 955 959
-
(2012)
Nat. Genet.
, vol.44
, pp. 955-959
-
-
Howie, B.1
Fuchsberger, C.2
Stephens, M.3
Marchini, J.4
Abecasis, G.R.5
-
28
-
-
70349324702
-
High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism
-
P. Soininen, A.J. Kangas, P. Würtz, T. Tukiainen, T. Tynkkynen, R. Laatikainen, M.R. Järvelin, M. Kähönen, T. Lehtimäki, J. Viikari, and et al. High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism Analyst (Lond.) 134 2009 1781 1785
-
(2009)
Analyst (Lond.)
, vol.134
, pp. 1781-1785
-
-
Soininen, P.1
Kangas, A.J.2
Würtz, P.3
Tukiainen, T.4
Tynkkynen, T.5
Laatikainen, R.6
Järvelin, M.R.7
Kähönen, M.8
Lehtimäki, T.9
Viikari, J.10
-
29
-
-
84924533418
-
Quantitative serum nuclear magnetic resonance metabolomics in cardiovascular epidemiology and genetics
-
P. Soininen, A.J. Kangas, P. Würtz, T. Suna, and M. Ala-Korpela Quantitative serum nuclear magnetic resonance metabolomics in cardiovascular epidemiology and genetics Circ Cardiovasc Genet 8 2015 192 206
-
(2015)
Circ Cardiovasc Genet
, vol.8
, pp. 192-206
-
-
Soininen, P.1
Kangas, A.J.2
Würtz, P.3
Suna, T.4
Ala-Korpela, M.5
-
30
-
-
78650665228
-
Metabonomic, transcriptomic, and genomic variation of a population cohort
-
M. Inouye, J. Kettunen, P. Soininen, K. Silander, S. Ripatti, L.S. Kumpula, E. Hämäläinen, P. Jousilahti, A.J. Kangas, S. Männistö, and et al. Metabonomic, transcriptomic, and genomic variation of a population cohort Mol. Syst. Biol. 6 2010 441
-
(2010)
Mol. Syst. Biol.
, vol.6
, pp. 441
-
-
Inouye, M.1
Kettunen, J.2
Soininen, P.3
Silander, K.4
Ripatti, S.5
Kumpula, L.S.6
Hämäläinen, E.7
Jousilahti, P.8
Kangas, A.J.9
Männistö, S.10
-
31
-
-
77950301214
-
Variance component model to account for sample structure in genome-wide association studies
-
H.M. Kang, J.H. Sul, S.K. Service, N.A. Zaitlen, S.Y. Kong, N.B. Freimer, C. Sabatti, and E. Eskin Variance component model to account for sample structure in genome-wide association studies Nat. Genet. 42 2010 348 354
-
(2010)
Nat. Genet.
, vol.42
, pp. 348-354
-
-
Kang, H.M.1
Sul, J.H.2
Service, S.K.3
Zaitlen, N.A.4
Kong, S.Y.5
Freimer, N.B.6
Sabatti, C.7
Eskin, E.8
-
32
-
-
77956586071
-
LocusZoom: Regional visualization of genome-wide association scan results
-
R.J. Pruim, R.P. Welch, S. Sanna, T.M. Teslovich, P.S. Chines, T.P. Gliedt, M. Boehnke, G.R. Abecasis, and C.J. Willer LocusZoom: regional visualization of genome-wide association scan results Bioinformatics 26 2010 2336 2337
-
(2010)
Bioinformatics
, vol.26
, pp. 2336-2337
-
-
Pruim, R.J.1
Welch, R.P.2
Sanna, S.3
Teslovich, T.M.4
Chines, P.S.5
Gliedt, T.P.6
Boehnke, M.7
Abecasis, G.R.8
Willer, C.J.9
-
33
-
-
84893763903
-
A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell
-
J.R. Kulzer, M.L. Stitzel, M.A. Morken, J.R. Huyghe, C. Fuchsberger, J. Kuusisto, M. Laakso, M. Boehnke, F.S. Collins, and K.L. Mohlke A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell Am. J. Hum. Genet. 94 2014 186 197
-
(2014)
Am. J. Hum. Genet.
, vol.94
, pp. 186-197
-
-
Kulzer, J.R.1
Stitzel, M.L.2
Morken, M.A.3
Huyghe, J.R.4
Fuchsberger, C.5
Kuusisto, J.6
Laakso, M.7
Boehnke, M.8
Collins, F.S.9
Mohlke, K.L.10
-
34
-
-
0347125328
-
JASPAR: An open-access database for eukaryotic transcription factor binding profiles
-
A. Sandelin, W. Alkema, P. Engström, W.W. Wasserman, and B. Lenhard JASPAR: an open-access database for eukaryotic transcription factor binding profiles Nucleic Acids Res. 32 2004 D91 D94
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. D91-D94
-
-
Sandelin, A.1
Alkema, W.2
Engström, P.3
Wasserman, W.W.4
Lenhard, B.5
-
35
-
-
0036707816
-
Identification of transcription factor binding sites in the human genome sequence
-
S. Levy, and S. Hannenhalli Identification of transcription factor binding sites in the human genome sequence Mamm. Genome 13 2002 510 514
-
(2002)
Mamm. Genome
, vol.13
, pp. 510-514
-
-
Levy, S.1
Hannenhalli, S.2
-
36
-
-
84937886899
-
Removing reference mapping biases using limited or no genotype data identifies allelic differences in protein binding at disease-associated loci
-
M.L. Buchkovich, K. Eklund, Q. Duan, Y. Li, K.L. Mohlke, and T.S. Furey Removing reference mapping biases using limited or no genotype data identifies allelic differences in protein binding at disease-associated loci BMC Med. Genomics 8 2015 43
-
(2015)
BMC Med. Genomics
, vol.8
, pp. 43
-
-
Buchkovich, M.L.1
Eklund, K.2
Duan, Q.3
Li, Y.4
Mohlke, K.L.5
Furey, T.S.6
-
37
-
-
77951820899
-
Fast and SNP-tolerant detection of complex variants and splicing in short reads
-
T.D. Wu, and S. Nacu Fast and SNP-tolerant detection of complex variants and splicing in short reads Bioinformatics 26 2010 873 881
-
(2010)
Bioinformatics
, vol.26
, pp. 873-881
-
-
Wu, T.D.1
Nacu, S.2
-
38
-
-
77952497530
-
Allelic expression imbalance at high-density lipoprotein cholesterol locus MMAB-MVK
-
M.P. Fogarty, R. Xiao, L. Prokunina-Olsson, L.J. Scott, and K.L. Mohlke Allelic expression imbalance at high-density lipoprotein cholesterol locus MMAB-MVK Hum. Mol. Genet. 19 2010 1921 1929
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 1921-1929
-
-
Fogarty, M.P.1
Xiao, R.2
Prokunina-Olsson, L.3
Scott, L.J.4
Mohlke, K.L.5
-
39
-
-
80051803605
-
Detection of cis-acting regulatory SNPs using allelic expression data
-
R. Xiao, and L.J. Scott Detection of cis-acting regulatory SNPs using allelic expression data Genet. Epidemiol. 35 2011 515 525
-
(2011)
Genet. Epidemiol.
, vol.35
, pp. 515-525
-
-
Xiao, R.1
Scott, L.J.2
-
40
-
-
77955505742
-
A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies
-
O. Stegle, L. Parts, R. Durbin, and J. Winn A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies PLoS Comput. Biol. 6 2010 e1000770
-
(2010)
PLoS Comput. Biol.
, vol.6
, pp. e1000770
-
-
Stegle, O.1
Parts, L.2
Durbin, R.3
Winn, J.4
-
41
-
-
84888264156
-
Practical guidelines for the comprehensive analysis of ChIP-seq data
-
T. Bailey, P. Krajewski, I. Ladunga, C. Lefebvre, Q. Li, T. Liu, P. Madrigal, C. Taslim, and J. Zhang Practical guidelines for the comprehensive analysis of ChIP-seq data PLoS Comput. Biol. 9 2013 e1003326
-
(2013)
PLoS Comput. Biol.
, vol.9
, pp. e1003326
-
-
Bailey, T.1
Krajewski, P.2
Ladunga, I.3
Lefebvre, C.4
Li, Q.5
Liu, T.6
Madrigal, P.7
Taslim, C.8
Zhang, J.9
-
42
-
-
61449218868
-
Targeted screening of cis-regulatory variation in human haplotypes
-
D.J. Verlaan, B. Ge, E. Grundberg, R. Hoberman, K.C. Lam, V. Koka, J. Dias, S. Gurd, N.W. Martin, H. Mallmin, and et al. Targeted screening of cis-regulatory variation in human haplotypes Genome Res. 19 2009 118 127
-
(2009)
Genome Res.
, vol.19
, pp. 118-127
-
-
Verlaan, D.J.1
Ge, B.2
Grundberg, E.3
Hoberman, R.4
Lam, K.C.5
Koka, V.6
Dias, J.7
Gurd, S.8
Martin, N.W.9
Mallmin, H.10
-
43
-
-
77954134112
-
A cis-acting regulatory variant in the IL2RA locus
-
H.Q. Qu, D.J. Verlaan, B. Ge, Y. Lu, K.C. Lam, R. Grabs, E. Harmsen, T.J. Hudson, H. Hakonarson, T. Pastinen, and C. Polychronakos A cis-acting regulatory variant in the IL2RA locus J. Immunol. 183 2009 5158 5162
-
(2009)
J. Immunol.
, vol.183
, pp. 5158-5162
-
-
Qu, H.Q.1
Verlaan, D.J.2
Ge, B.3
Lu, Y.4
Lam, K.C.5
Grabs, R.6
Harmsen, E.7
Hudson, T.J.8
Hakonarson, H.9
Pastinen, T.10
Polychronakos, C.11
-
44
-
-
84923326765
-
Genetic and epigenetic fine mapping of causal autoimmune disease variants
-
K.K. Farh, A. Marson, J. Zhu, M. Kleinewietfeld, W.J. Housley, S. Beik, N. Shoresh, H. Whitton, R.J. Ryan, A.A. Shishkin, and et al. Genetic and epigenetic fine mapping of causal autoimmune disease variants Nature 518 2015 337 343
-
(2015)
Nature
, vol.518
, pp. 337-343
-
-
Farh, K.K.1
Marson, A.2
Zhu, J.3
Kleinewietfeld, M.4
Housley, W.J.5
Beik, S.6
Shoresh, N.7
Whitton, H.8
Ryan, R.J.9
Shishkin, A.A.10
-
45
-
-
84927559450
-
Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers
-
L.J. Core, A.L. Martins, C.G. Danko, C.T. Waters, A. Siepel, and J.T. Lis Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers Nat. Genet. 46 2014 1311 1320
-
(2014)
Nat. Genet.
, vol.46
, pp. 1311-1320
-
-
Core, L.J.1
Martins, A.L.2
Danko, C.G.3
Waters, C.T.4
Siepel, A.5
Lis, J.T.6
-
46
-
-
79953751486
-
C/EBPβ mediates growth hormone-regulated expression of multiple target genes
-
T.X. Cui, G. Lin, C.R. LaPensee, A.A. Calinescu, M. Rathore, C. Streeter, G. Piwien-Pilipuk, N. Lanning, H. Jin, C. Carter-Su, and et al. C/EBPβ mediates growth hormone-regulated expression of multiple target genes Mol. Endocrinol. 25 2011 681 693
-
(2011)
Mol. Endocrinol.
, vol.25
, pp. 681-693
-
-
Cui, T.X.1
Lin, G.2
LaPensee, C.R.3
Calinescu, A.A.4
Rathore, M.5
Streeter, C.6
Piwien-Pilipuk, G.7
Lanning, N.8
Jin, H.9
Carter-Su, C.10
-
47
-
-
0031435337
-
Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene
-
T. Tanaka, N. Yoshida, T. Kishimoto, and S. Akira Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene EMBO J. 16 1997 7432 7443
-
(1997)
EMBO J.
, vol.16
, pp. 7432-7443
-
-
Tanaka, T.1
Yoshida, N.2
Kishimoto, T.3
Akira, S.4
-
48
-
-
0030987656
-
An essential role for C/EBPbeta in female reproduction
-
E. Sterneck, L. Tessarollo, and P.F. Johnson An essential role for C/EBPbeta in female reproduction Genes Dev. 11 1997 2153 2162
-
(1997)
Genes Dev.
, vol.11
, pp. 2153-2162
-
-
Sterneck, E.1
Tessarollo, L.2
Johnson, P.F.3
-
49
-
-
0032525338
-
The C/EBPbeta transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland
-
G.W. Robinson, P.F. Johnson, L. Hennighausen, and E. Sterneck The C/EBPbeta transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland Genes Dev. 12 1998 1907 1916
-
(1998)
Genes Dev.
, vol.12
, pp. 1907-1916
-
-
Robinson, G.W.1
Johnson, P.F.2
Hennighausen, L.3
Sterneck, E.4
-
50
-
-
84859064895
-
Regulation of C/EBPβ and resulting functions in cells of the monocytic lineage
-
R. Huber, D. Pietsch, T. Panterodt, and K. Brand Regulation of C/EBPβ and resulting functions in cells of the monocytic lineage Cell. Signal. 24 2012 1287 1296
-
(2012)
Cell. Signal.
, vol.24
, pp. 1287-1296
-
-
Huber, R.1
Pietsch, D.2
Panterodt, T.3
Brand, K.4
-
51
-
-
84872420346
-
CCAAT/enhancer binding protein β deletion increases mitochondrial function and protects mice from LXR-induced hepatic steatosis
-
S.M. Rahman, M. Choudhury, R.C. Janssen, K.C. Baquero, M. Miyazaki, and J.E. Friedman CCAAT/enhancer binding protein β deletion increases mitochondrial function and protects mice from LXR-induced hepatic steatosis Biochem. Biophys. Res. Commun. 430 2013 336 339
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.430
, pp. 336-339
-
-
Rahman, S.M.1
Choudhury, M.2
Janssen, R.C.3
Baquero, K.C.4
Miyazaki, M.5
Friedman, J.E.6
-
52
-
-
0035864637
-
Hepatic lipase promoter activity is reduced by the C-480T and G-216A substitutions present in the common LIPC gene variant, and is increased by Upstream Stimulatory Factor
-
G.J. Botma, A.J. Verhoeven, and H. Jansen Hepatic lipase promoter activity is reduced by the C-480T and G-216A substitutions present in the common LIPC gene variant, and is increased by Upstream Stimulatory Factor Atherosclerosis 154 2001 625 632
-
(2001)
Atherosclerosis
, vol.154
, pp. 625-632
-
-
Botma, G.J.1
Verhoeven, A.J.2
Jansen, H.3
-
53
-
-
1942469517
-
Upstream stimulatory factor (USF) proteins induce human TGF-beta1 gene activation via the glucose-response element-1013/-1002 in mesangial cells: Up-regulation of USF activity by the hexosamine biosynthetic pathway
-
C. Weigert, K. Brodbeck, M. Sawadogo, H.U. Häring, and E.D. Schleicher Upstream stimulatory factor (USF) proteins induce human TGF-beta1 gene activation via the glucose-response element-1013/-1002 in mesangial cells: up-regulation of USF activity by the hexosamine biosynthetic pathway J. Biol. Chem. 279 2004 15908 15915
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 15908-15915
-
-
Weigert, C.1
Brodbeck, K.2
Sawadogo, M.3
Häring, H.U.4
Schleicher, E.D.5
-
54
-
-
33846477321
-
Upstream stimulatory factors regulate the C/EBP alpha gene during differentiation of 3T3-L1 preadipocytes
-
J.W. Kim, H. Monila, A. Pandey, and M.D. Lane Upstream stimulatory factors regulate the C/EBP alpha gene during differentiation of 3T3-L1 preadipocytes Biochem. Biophys. Res. Commun. 354 2007 517 521
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.354
, pp. 517-521
-
-
Kim, J.W.1
Monila, H.2
Pandey, A.3
Lane, M.D.4
-
55
-
-
77950358523
-
Upstream transcription factor 1 influences plasma lipid and metabolic traits in mice
-
S. Wu, R. Mar-Heyming, E.Z. Dugum, N.A. Kolaitis, H. Qi, P. Pajukanta, L.W. Castellani, A.J. Lusis, and T.A. Drake Upstream transcription factor 1 influences plasma lipid and metabolic traits in mice Hum. Mol. Genet. 19 2010 597 608
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 597-608
-
-
Wu, S.1
Mar-Heyming, R.2
Dugum, E.Z.3
Kolaitis, N.A.4
Qi, H.5
Pajukanta, P.6
Castellani, L.W.7
Lusis, A.J.8
Drake, T.A.9
-
56
-
-
45149108420
-
Mapping the genetic architecture of gene expression in human liver
-
E.E. Schadt, C. Molony, E. Chudin, K. Hao, X. Yang, P.Y. Lum, A. Kasarskis, B. Zhang, S. Wang, C. Suver, and et al. Mapping the genetic architecture of gene expression in human liver PLoS Biol. 6 2008 e107
-
(2008)
PLoS Biol.
, vol.6
, pp. e107
-
-
Schadt, E.E.1
Molony, C.2
Chudin, E.3
Hao, K.4
Yang, X.5
Lum, P.Y.6
Kasarskis, A.7
Zhang, B.8
Wang, S.9
Suver, C.10
-
57
-
-
78649246183
-
Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease
-
L. Folkersen, F. van't Hooft, E. Chernogubova, H.E. Agardh, G.K. Hansson, U. Hedin, J. Liska, A.C. Syvänen, G. Paulsson-Berne, A. Franco-Cereceda, et al. BiKE and ASAP study groups Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease Circ Cardiovasc Genet 3 2010 365 373
-
(2010)
Circ Cardiovasc Genet
, vol.3
, pp. 365-373
-
-
Folkersen, L.1
Van'T Hooft, F.2
Chernogubova, E.3
Agardh, H.E.4
Hansson, G.K.5
Hedin, U.6
Liska, J.7
Syvänen, A.C.8
Paulsson-Berne, G.9
Franco-Cereceda, A.10
-
58
-
-
84929001104
-
Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
-
GTEx Consortium Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans Science 348 2015 648 660
-
(2015)
Science
, vol.348
, pp. 648-660
-
-
-
59
-
-
84857648463
-
Genome-wide association study identifies multiple loci influencing human serum metabolite levels
-
J. Kettunen, T. Tukiainen, A.P. Sarin, A. Ortega-Alonso, E. Tikkanen, L.P. Lyytikäinen, A.J. Kangas, P. Soininen, P. Würtz, K. Silander, and et al. Genome-wide association study identifies multiple loci influencing human serum metabolite levels Nat. Genet. 44 2012 269 276
-
(2012)
Nat. Genet.
, vol.44
, pp. 269-276
-
-
Kettunen, J.1
Tukiainen, T.2
Sarin, A.P.3
Ortega-Alonso, A.4
Tikkanen, E.5
Lyytikäinen, L.P.6
Kangas, A.J.7
Soininen, P.8
Würtz, P.9
Silander, K.10
-
60
-
-
0032901331
-
A novel endothelial-derived lipase that modulates HDL metabolism
-
M. Jaye, K.J. Lynch, J. Krawiec, D. Marchadier, C. Maugeais, K. Doan, V. South, D. Amin, M. Perrone, and D.J. Rader A novel endothelial-derived lipase that modulates HDL metabolism Nat. Genet. 21 1999 424 428
-
(1999)
Nat. Genet.
, vol.21
, pp. 424-428
-
-
Jaye, M.1
Lynch, K.J.2
Krawiec, J.3
Marchadier, D.4
Maugeais, C.5
Doan, K.6
South, V.7
Amin, D.8
Perrone, M.9
Rader, D.J.10
-
61
-
-
0035988350
-
Characterization of the lipolytic activity of endothelial lipase
-
M.G. McCoy, G.S. Sun, D. Marchadier, C. Maugeais, J.M. Glick, and D.J. Rader Characterization of the lipolytic activity of endothelial lipase J. Lipid Res. 43 2002 921 929
-
(2002)
J. Lipid Res.
, vol.43
, pp. 921-929
-
-
McCoy, M.G.1
Sun, G.S.2
Marchadier, D.3
Maugeais, C.4
Glick, J.M.5
Rader, D.J.6
-
62
-
-
27244458482
-
Evidence that endothelial lipase remodels high density lipoproteins without mediating the dissociation of apolipoprotein A-I
-
A. Jahangiri, D.J. Rader, D. Marchadier, L.K. Curtiss, D.J. Bonnet, and K.A. Rye Evidence that endothelial lipase remodels high density lipoproteins without mediating the dissociation of apolipoprotein A-I J. Lipid Res. 46 2005 896 903
-
(2005)
J. Lipid Res.
, vol.46
, pp. 896-903
-
-
Jahangiri, A.1
Rader, D.J.2
Marchadier, D.3
Curtiss, L.K.4
Bonnet, D.J.5
Rye, K.A.6
-
63
-
-
84891697734
-
Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits
-
O. Corradin, A. Saiakhova, B. Akhtar-Zaidi, L. Myeroff, J. Willis, R. Cowper-Sal lari, M. Lupien, S. Markowitz, and P.C. Scacheri Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits Genome Res. 24 2014 1 13
-
(2014)
Genome Res.
, vol.24
, pp. 1-13
-
-
Corradin, O.1
Saiakhova, A.2
Akhtar-Zaidi, B.3
Myeroff, L.4
Willis, J.5
Cowper-Sal Lari, R.6
Lupien, M.7
Markowitz, S.8
Scacheri, P.C.9
-
64
-
-
84929206967
-
Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer
-
H. He, W. Li, S. Liyanarachchi, M. Srinivas, Y. Wang, K. Akagi, Y. Wang, D. Wu, Q. Wang, V. Jin, and et al. Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer Proc. Natl. Acad. Sci. USA 112 2015 6128 6133
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. 6128-6133
-
-
He, H.1
Li, W.2
Liyanarachchi, S.3
Srinivas, M.4
Wang, Y.5
Akagi, K.6
Wang, Y.7
Wu, D.8
Wang, Q.9
Jin, V.10
|