메뉴 건너뛰기




Volumn 37, Issue 11, 2014, Pages 777-784

Cholesteryl ester transfer protein (CETP) deficiency and CETP inhibitors

Author keywords

CETP deficiency; Cholesteryl ester transfer protein (CETP); HDL LDL; Hyper HDL cholesterolemia; Inhibitors of CETP

Indexed keywords

ANACETRAPIB; ANTISENSE OLIGONUCLEOTIDE; CHOLESTEROL ESTER TRANSFER PROTEIN; CHOLESTEROL ESTER TRANSFER PROTEIN INHIBITOR; EVACETRAPIB; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; BENZODIAZEPINE DERIVATIVE; CETP PROTEIN, HUMAN; CHOLESTEROL; OXAZOLIDINONE DERIVATIVE;

EID: 84964315855     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.14348/molcells.2014.0265     Document Type: Review
Times cited : (45)

References (42)
  • 1
  • 3
    • 84884139889 scopus 로고    scopus 로고
    • Antisense oligonucleotide inhibition of cholesteryl ester transfer protein enhances RCT in hyperlipidemic, CETP transgenic, LDLr-/- mice
    • Bell, T.A., Graham, M.J., Lee, R.G., Mullick, A.E., Fu, W., Norris, D., and Crooke, R.M. (2013). Antisense oligonucleotide inhibition of cholesteryl ester transfer protein enhances RCT in hyperlipidemic, CETP transgenic, LDLr-/- mice. J. Lipid Res. 54, 2647-2657.
    • (2013) J. Lipid Res. , vol.54 , pp. 2647-2657
    • Bell, T.A.1    Graham, M.J.2    Lee, R.G.3    Mullick, A.E.4    Fu, W.5    Norris, D.6    Crooke, R.M.7
  • 4
    • 1842765494 scopus 로고    scopus 로고
    • Increasing HDL cholesterol levels
    • Brewer, H.B. Jr. (2004). Increasing HDL cholesterol levels. N. Engl. J. Med. 350, 1491-1494.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 1491-1494
    • Brewer, H.B.1
  • 7
    • 2142763867 scopus 로고    scopus 로고
    • A prospective study of HDLC and cholesteryl ester transfer protein gene mutations and the risk of coronary heart disease in the elderly
    • Curb, J.D., Abbott, R.D., Rodriguez, B.L., Masaki, K., Chen, R., Sharp, D.S., and Tall, A.R. (2004). A prospective study of HDLC and cholesteryl ester transfer protein gene mutations and the risk of coronary heart disease in the elderly. J. Lipid Res. 45, 948-953.
    • (2004) J. Lipid Res. , vol.45 , pp. 948-953
    • Curb, J.D.1    Abbott, R.D.2    Rodriguez, B.L.3    Masaki, K.4    Chen, R.5    Sharp, D.S.6    Tall, A.R.7
  • 9
    • 0032572086 scopus 로고    scopus 로고
    • Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study
    • Downs, J.R., Clearfield, M., Weis, S., Whitney, E., Shapiro, D.R., Beere, P.A., Langendorfer, A., Stein, E.A., Kruyer, W., Gotto, A.M. Jr., et al. (1998). Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study. JAMA 279, 1615-1622.
    • (1998) JAMA , vol.279 , pp. 1615-1622
    • Downs, J.R.1    Clearfield, M.2    Weis, S.3    Whitney, E.4    Shapiro, D.R.5    Beere, P.A.6    Langendorfer, A.7    Stein, E.A.8    Kruyer, W.9    Gotto, A.M.10
  • 10
    • 0028061579 scopus 로고
    • Inhibition of cholesteryl ester transfer protein activity in hamsters alters HDL lipid composition
    • Gaynor, B.J., Sand, T., Clark, R.W., Aiello, R.J., Bamberger, M.J., and Moberly, J.B. (1994). Inhibition of cholesteryl ester transfer protein activity in hamsters alters HDL lipid composition. Atherosclerosis 110, 101-109.
    • (1994) Atherosclerosis , vol.110 , pp. 101-109
    • Gaynor, B.J.1    Sand, T.2    Clark, R.W.3    Aiello, R.J.4    Bamberger, M.J.5    Moberly, J.B.6
  • 11
  • 12
    • 0019520249 scopus 로고
    • Lipoproteins, cardiovascular disease, and death. The Framingham study
    • Gordon, T., Kannel, W.B., Castelli, W.P., and Dawber, T.R. (1981). Lipoproteins, cardiovascular disease, and death. The Framingham study. Arch. Intern. Med. 141, 1128-1131.
    • (1981) Arch. Intern. Med. , vol.141 , pp. 1128-1131
    • Gordon, T.1    Kannel, W.B.2    Castelli, W.P.3    Dawber, T.R.4
  • 13
    • 0020013576 scopus 로고
    • Differences in plasma cholesteryl ester transfer activity in sixteen vertebrate species
    • Ha, Y.C., and Barter, P.J. (1982). Differences in plasma cholesteryl ester transfer activity in sixteen vertebrate species. Comp. Biochem. Physiol. B. 71, 265-269.
    • (1982) Comp. Biochem. Physiol. B. , vol.71 , pp. 265-269
    • Ha, Y.C.1    Barter, P.J.2
  • 14
    • 84983084669 scopus 로고    scopus 로고
    • CETP (cholesteryl esters transfer protein) deficiency caused by genetic mutation in the CETP gene in normal Korean population
    • Han K.H., Park, Y.B., Chae, I.H., Kim, H.S., Sohn, D.W., Oh, B.H., Lee, M.M, Choi, Y.S., Seo, J.D., Lee, Y.W., et al. (1996). CETP (cholesteryl esters transfer protein) deficiency caused by genetic mutation in the CETP gene in normal Korean population. Korean Circ. J. 26, 500-506.
    • (1996) Korean Circ. J. , vol.26 , pp. 500-506
    • Han, K.H.1    Park, Y.B.2    Chae, I.H.3    Kim, H.S.4    Sohn, D.W.5    Oh, B.H.6    Lee, M.M.7    Choi, Y.S.8    Seo, J.D.9    Lee, Y.W.10
  • 15
    • 0030798832 scopus 로고    scopus 로고
    • Clinical characteristics of double heterozygotes with familial hypercholesterolemia and cholesteryl ester transfer protein deficiency
    • Haraki, T., Inazu, A., Yagi, K., Kajinami, K., Koizumi, J., and Mabuchi, H. (1997). Clinical characteristics of double heterozygotes with familial hypercholesterolemia and cholesteryl ester transfer protein deficiency. Atherosclerosis 132, 229-236.
    • (1997) Atherosclerosis , vol.132 , pp. 229-236
    • Haraki, T.1    Inazu, A.2    Yagi, K.3    Kajinami, K.4    Koizumi, J.5    Mabuchi, H.6
  • 16
    • 0028857779 scopus 로고
    • Atherosclerotic disease in marked hyperalphalipoproteinemia. Combined reduction of cholesteryl ester transfer protein and hepatic triglyceride lipase
    • Hirano, K., Yamashita, S., Kuga, Y., Sakai, N., Nozaki, S., Kihara, S., Arai, T., Yanagi, K., Takami, S., Menju, M., et al. (1995). Atherosclerotic disease in marked hyperalphalipoproteinemia. Combined reduction of cholesteryl ester transfer protein and hepatic triglyceride lipase. Arterioscler. Thromb. Vasc. Biol. 15, 1849-1856.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 1849-1856
    • Hirano, K.1    Yamashita, S.2    Kuga, Y.3    Sakai, N.4    Nozaki, S.5    Kihara, S.6    Arai, T.7    Yanagi, K.8    Takami, S.9    Menju, M.10
  • 17
    • 16944362351 scopus 로고    scopus 로고
    • Genetic cholesteryl ester transfer protein deficiency is extremely frequent in the Omagari area of Japan. Marked hyperalphalipoproteinemia caused by CETP gene mutation is not associated with longevity
    • Hirano, K., Yamashita, S., Nakajima, N., Arai, T., Maruyama, T., Yoshida, Y., Ishigami, M., Sakai, N., Kameda-Takemura, K., and Matsuzawa, Y. (1997). Genetic cholesteryl ester transfer protein deficiency is extremely frequent in the Omagari area of Japan. Marked hyperalphalipoproteinemia caused by CETP gene mutation is not associated with longevity. Arterioscler. Thromb. Vasc. Biol. 17, 1053-1059.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 1053-1059
    • Hirano, K.1    Yamashita, S.2    Nakajima, N.3    Arai, T.4    Maruyama, T.5    Yoshida, Y.6    Ishigami, M.7    Sakai, N.8    Kameda-Takemura, K.9    Matsuzawa, Y.10
  • 18
    • 0036907139 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein inhibitor (JTT-705) and the development of atherosclerosis in rabbits with severe hypercholesterolaemia
    • Huang, Z., Inazu, A., Nohara, A., Higashikata, T., and Mabuchi, H. (2002). Cholesteryl ester transfer protein inhibitor (JTT-705) and the development of atherosclerosis in rabbits with severe hypercholesterolaemia. Clin. Sci. (Lond). 103, 587-594.
    • (2002) Clin. Sci. (Lond). , vol.103 , pp. 587-594
    • Huang, Z.1    Inazu, A.2    Nohara, A.3    Higashikata, T.4    Mabuchi, H.5
  • 19
    • 0038417041 scopus 로고    scopus 로고
    • Therapeutic implications of cholesteryl ester transfer protein inhibitors in hyperlipidemia and low high-density lipoprotein-cholesterolemia
    • Inazu, A.1., and Mabuchi, H. (2003). Therapeutic implications of cholesteryl ester transfer protein inhibitors in hyperlipidemia and low high-density lipoprotein-cholesterolemia. Curr. Opin. Investig. Drugs 4, 291-297.
    • (2003) Curr. Opin. Investig. Drugs , vol.4 , pp. 291-297
    • Inazu, A.1    Mabuchi, H.2
  • 21
    • 0028135441 scopus 로고
    • Genetic cholesteryl ester transfer protein deficiency caused by two prevalent mutations as a major determinant of increased levels of high-density lipoprotein cholesterol
    • Inazu, A.1., Jiang, X.C., Haraki, T., Yagi, K., Kamon, N., Koizumi, J., Mabuchi, H., Takeda, R., Takata, K., Moriyama, Y., et al. (1994). Genetic cholesteryl ester transfer protein deficiency caused by two prevalent mutations as a major determinant of increased levels of high-density lipoprotein cholesterol. J. Clin. Invest. 94, 1872-1882.
    • (1994) J. Clin. Invest. , vol.94 , pp. 1872-1882
    • Inazu, A.1    Jiang, X.C.2    Haraki, T.3    Yagi, K.4    Kamon, N.5    Koizumi, J.6    Mabuchi, H.7    Takeda, R.8    Takata, K.9    Moriyama, Y.10
  • 24
    • 14944381287 scopus 로고    scopus 로고
    • HDL as a target in the treatment of atherosclerotic cardiovascular disease
    • Linsel-Nitschke P.I., and Tall A.R. (2005). HDL as a target in the treatment of atherosclerotic cardiovascular disease. Nat. Rev. Drug Discov. 4, 193-205.
    • (2005) Nat. Rev. Drug Discov. , vol.4 , pp. 193-205
    • Linsel-Nitschke, P.I.1    Tall, A.R.2
  • 25
    • 0027325516 scopus 로고
    • Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein
    • Marotti, K.R., Castle, C.K., Boyle, T.P., Lin, A.H., Murray, R.W., and Melchior, G.W. (1993). Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein. Nature 364, 73-75.
    • (1993) Nature , vol.364 , pp. 73-75
    • Marotti, K.R.1    Castle, C.K.2    Boyle, T.P.3    Lin, A.H.4    Murray, R.W.5    Melchior, G.W.6
  • 26
    • 33646409606 scopus 로고    scopus 로고
    • HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway
    • Matsuura, F., Wang, N., Chen, W., Jiang, X.C., and Tall, A.R. (2006). HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway. J. Clin. Invest. 116, 1435-1442.
    • (2006) J. Clin. Invest. , vol.116 , pp. 1435-1442
    • Matsuura, F.1    Wang, N.2    Chen, W.3    Jiang, X.C.4    Tall, A.R.5
  • 28
    • 17444448251 scopus 로고    scopus 로고
    • A low prevalence of coronary heart disease among subjects with increased high-density lipoprotein cholesterol levels, including those with plasma cholesteryl ester transfer protein deficiency
    • Moriyama, Y., Okamura, T., Inazu, A., Doi, M., Iso, H., Mouri, Y., Ishikawa, Y., Suzuki, H., Iida, M., Koizumi, J., et al. (1998). A low prevalence of coronary heart disease among subjects with increased high-density lipoprotein cholesterol levels, including those with plasma cholesteryl ester transfer protein deficiency. Prev. Med. 27, 659-667.
    • (1998) Prev. Med. , vol.27 , pp. 659-667
    • Moriyama, Y.1    Okamura, T.2    Inazu, A.3    Doi, M.4    Iso, H.5    Mouri, Y.6    Ishikawa, Y.7    Suzuki, H.8    Iida, M.9    Koizumi, J.10
  • 29
    • 0037126526 scopus 로고    scopus 로고
    • Third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report
    • National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). (2002). Third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report. Circulation 106, 3143-3421.
    • (2002) Circulation , vol.106 , pp. 3143-3421
  • 31
    • 0034644214 scopus 로고    scopus 로고
    • A cholesteryl ester transfer protein in hibitor attenuates atherosclerosis in rabbits
    • Okamoto, H., Yonemori, F., Wakitani, K., Minowa, T., Maeda, K., and Shinkai, H. (2000). A cholesteryl ester transfer protein in hibitor attenuates atherosclerosis in rabbits. Nature 406, 203-207.
    • (2000) Nature , vol.406 , pp. 203-207
    • Okamoto, H.1    Yonemori, F.2    Wakitani, K.3    Minowa, T.4    Maeda, K.5    Shinkai, H.6
  • 32
    • 18744373337 scopus 로고    scopus 로고
    • High-density lipoprotein, but not low-density lipoprotein cholesterol levels influence short-term prognosis after acute coronary syndrome: Results from the MIRACLE trial
    • Olsson, A.G., Schwartz, G.G., Szarek, M., Sasiela, W.J., Ezekowitz, M.D., Ganz, P., Oliver, M.F., Waters, D., and Zeiher, A. (2005). High-density lipoprotein, but not low-density lipoprotein cholesterol levels influence short-term prognosis after acute coronary syndrome: results from the MIRACLE trial. Eur. Heart J. 26, 890-896.
    • (2005) Eur. Heart J. , vol.26 , pp. 890-896
    • Olsson, A.G.1    Schwartz, G.G.2    Szarek, M.3    Sasiela, W.J.4    Ezekowitz, M.D.5    Ganz, P.6    Oliver, M.F.7    Waters, D.8    Zeiher, A.9
  • 36
    • 84880133007 scopus 로고    scopus 로고
    • Effects of cholesteryl ester transfer protein inhibitors on human lipoprotein metabolism: Why have they failed in lowering coronary heart disease risk? Curr
    • Schaefer, E.J. (2013). Effects of cholesteryl ester transfer protein inhibitors on human lipoprotein metabolism: why have they failed in lowering coronary heart disease risk? Curr. Opin. Lipidol. 24, 259-264.
    • (2013) Opin. Lipidol. , vol.24 , pp. 259-264
    • Schaefer, E.J.1
  • 37
    • 0028883828 scopus 로고
    • For the West of Scotland Coronary Prevention Study Group: Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • Shepherd, J., Cobbe, S.M., Ford, I., Isles, C.G., Lorimer, A.R., MacFarlane, P.W., McKillop, J.H., and Packard, C.J. (1995). For the West of Scotland Coronary Prevention Study Group: Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N. Engl. J. Med. 333, 1301-1307.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3    Isles, C.G.4    Lorimer, A.R.5    MacFarlane, P.W.6    McKillop, J.H.7    Packard, C.J.8
  • 38
    • 30444432694 scopus 로고    scopus 로고
    • Oral cholesteryl ester transfer protein (CETP) inhibitors: A potential new approach for treating coronary artery disease
    • Sikorski, J.A. (2006). Oral cholesteryl ester transfer protein (CETP) inhibitors: a potential new approach for treating coronary artery disease. J. Med. Chem. 49, 1-22.
    • (2006) J. Med. Chem. , vol.49 , pp. 1-22
    • Sikorski, J.A.1
  • 39
    • 0032570684 scopus 로고    scopus 로고
    • Effect of antisense oligonucleotides against cholesteryl ester transfer protein on the development of atherosclerosis in cholesterol-fed rabbits
    • Sugano, M., Makino, N., Sawada, S., Otsuka, S., Watanabe, M., Okamoto, H., Kamada, M., and Mizushima, A. (1998). Effect of antisense oligonucleotides against cholesteryl ester transfer protein on the development of atherosclerosis in cholesterol-fed rabbits. J. Biol. Chem. 273, 5033-5036.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5033-5036
    • Sugano, M.1    Makino, N.2    Sawada, S.3    Otsuka, S.4    Watanabe, M.5    Okamoto, H.6    Kamada, M.7    Mizushima, A.8
  • 40
    • 0027275449 scopus 로고
    • Plasma cholesteryl ester transfer protein
    • Tall, A.R. (1993). Plasma cholesteryl ester transfer protein. J. Lipid Res. 34, 1255-1274.
    • (1993) J. Lipid Res. , vol.34 , pp. 1255-1274
    • Tall, A.R.1
  • 41
    • 4544384058 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein and coronary artery disease: An observation with therapeutic implications
    • Wolfe, M.L., and Rader, D.J. (2004). Cholesteryl ester transfer protein and coronary artery disease: an observation with therapeutic implications. Circulation 110, 1338-1340.
    • (2004) Circulation , vol.110 , pp. 1338-1340
    • Wolfe, M.L.1    Rader, D.J.2
  • 42
    • 0029948968 scopus 로고    scopus 로고
    • Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels
    • Zhong, S., Sharp, D.S., Grove, J.S., Bruce, C., Yano, K., Curb, J.D., and Tall, A.R. (1996). Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels. J. Clin. Invest. 97, 2917-2923.
    • (1996) J. Clin. Invest. , vol.97 , pp. 2917-2923
    • Zhong, S.1    Sharp, D.S.2    Grove, J.S.3    Bruce, C.4    Yano, K.5    Curb, J.D.6    Tall, A.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.