메뉴 건너뛰기




Volumn 103, Issue 6, 2002, Pages 587-594

Cholesteryl ester transfer protein inhibitor (JTT-705) and the development of atherosclerosis in rabbits with severe hypercholesterolaemia

Author keywords

Atherosclerosis; CETP; Chemical inhibitor; HDL; Rabbit

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; 2 METHYLPROPANETHIOIC ACID S [2 [1 (2 ETHYLBUTYL)CYCLOHEXYLCARBOXAMIDO]PHENYL] ESTER; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN LIPASE; LIVER TRIACYLGLYCEROL LIPASE; LOW DENSITY LIPOPROTEIN; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN;

EID: 0036907139     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs1030587     Document Type: Article
Times cited : (110)

References (19)
  • 1
    • 0027275449 scopus 로고
    • Plasma cholesteryl ester transfer protein
    • Tall, A. R. (1993) Plasma cholesteryl ester transfer protein. J. Lipid Res. 34, 1255-1274
    • (1993) J. Lipid Res. , vol.34 , pp. 1255-1274
    • Tall, A.R.1
  • 2
    • 0028887870 scopus 로고
    • Molecular physiology of reverse cholesterol transport
    • Fielding, C. J. and Fielding, P. E. (1995) Molecular physiology of reverse cholesterol transport. J. Lipid Res. 36, 211-228
    • (1995) J. Lipid Res. , vol.36 , pp. 211-228
    • Fielding, C.J.1    Fielding, P.E.2
  • 3
    • 0025104275 scopus 로고
    • Increased high density lipoprotein caused by a common cholesteryl ester transfer protein gene mutation
    • Inazu, A., Brown, M. L., Hesler, C. B. et al. (1990) Increased high density lipoprotein caused by a common cholesteryl ester transfer protein gene mutation. N. Engl. J. Med. 323, 1234-1238
    • (1990) N. Engl. J. Med. , vol.323 , pp. 1234-1238
    • Inazu, A.1    Brown, M.L.2    Hesler, C.B.3
  • 4
    • 17444448251 scopus 로고    scopus 로고
    • A low prevalence of coronary heart disease among subjects with increased high-density lipoprotein cholesterol levels, including those with plasma cholesteryl ester transfer protein deficiency
    • Moriyama, Y., Okamura, T., Inazu, A. et al. (1998) A low prevalence of coronary heart disease among subjects with increased high-density lipoprotein cholesterol levels, including those with plasma cholesteryl ester transfer protein deficiency. Prev. Med. 27, 659-667
    • (1998) Prev. Med. , vol.27 , pp. 659-667
    • Moriyama, Y.1    Okamura, T.2    Inazu, A.3
  • 5
    • 0029948968 scopus 로고    scopus 로고
    • Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels
    • Zhong, S., Sharp, D. S., Grove, J. S., Bruce, C., Yano, K., Curb, J. D. and Tall, A. R. (1996) Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels. J. Clin. Invest. 97, 2917-2923
    • (1996) J. Clin. Invest. , vol.97 , pp. 2917-2923
    • Zhong, S.1    Sharp, D.S.2    Grove, J.S.3    Bruce, C.4    Yano, K.5    Curb, J.D.6    Tall, A.R.7
  • 6
    • 0031942155 scopus 로고    scopus 로고
    • Relationship of HDL and coronary heart disease to a common amino acid polymorphism in the cholesteryl ester transfer protein in men with and without hypertriglyceridemia
    • Bruce, C., Sharp, D. S. and Tall, A. R. (1998) Relationship of HDL and coronary heart disease to a common amino acid polymorphism in the cholesteryl ester transfer protein in men with and without hypertriglyceridemia. J. Lipid Res. 39, 1071-1078
    • (1998) J. Lipid Res. , vol.39 , pp. 1071-1078
    • Bruce, C.1    Sharp, D.S.2    Tall, A.R.3
  • 7
    • 0030798832 scopus 로고    scopus 로고
    • Clinical characteristics of double heterozygotes with familial hypercholesterolemia and cholesteryl ester transfer protein deficiency
    • Haraki, T., Inazu, A., Yagi, K., Kajinami, K., Koizumi, J. and Mabuchi, H. (1997) Clinical characteristics of double heterozygotes with familial hypercholesterolemia and cholesteryl ester transfer protein deficiency. Atherosclerosis 132, 229-236
    • (1997) Atherosclerosis , vol.132 , pp. 229-236
    • Haraki, T.1    Inazu, A.2    Yagi, K.3    Kajinami, K.4    Koizumi, J.5    Mabuchi, H.6
  • 8
    • 0032570684 scopus 로고    scopus 로고
    • Effect of antisense oligonucleotides against cholesteryl ester transfer protein on the development of atherosclerosis in cholesterol-fed rabbits
    • Sugano, M., Makino, N., Sawada, S. et al. (1998) Effect of antisense oligonucleotides against cholesteryl ester transfer protein on the development of atherosclerosis in cholesterol-fed rabbits. J. Biol. Chem. 273, 5033-5036
    • (1998) J. Biol. Chem. , vol.273 , pp. 5033-5036
    • Sugano, M.1    Makino, N.2    Sawada, S.3
  • 9
    • 0033822810 scopus 로고    scopus 로고
    • Vaccine-induced antibodies inhibit CETP activity in vivo and reduce aortic lesions in a rabbit model of atherosclerosis
    • Rittershaus, C. W., Miller, D. P., Thomas, L. J. et al. (2000) Vaccine-induced antibodies inhibit CETP activity in vivo and reduce aortic lesions in a rabbit model of atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 20, 2106-2112
    • (2000) Arterioscler. Thromb. Vasc. Biol. , vol.20 , pp. 2106-2112
    • Rittershaus, C.W.1    Miller, D.P.2    Thomas, L.J.3
  • 10
    • 0034644214 scopus 로고    scopus 로고
    • A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits
    • Okamoto, H., Yonemori, F., Wakitani, K., Minowa, T., Maeda, K. and Shinkai, H. (2000) A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits. Nature (London) 406, 203-207
    • (2000) Nature (London) , vol.406 , pp. 203-207
    • Okamoto, H.1    Yonemori, F.2    Wakitani, K.3    Minowa, T.4    Maeda, K.5    Shinkai, H.6
  • 11
    • 0018954886 scopus 로고
    • A selective decline of post-heparin plasma hepatic triglyceride lipase in hypothyroid rats
    • Murase, T. and Uchiyama, H. (1980) A selective decline of post-heparin plasma hepatic triglyceride lipase in hypothyroid rats. Metab. Clin. Exp. 29, 797-801
    • (1980) Metab. Clin. Exp. , vol.29 , pp. 797-801
    • Murase, T.1    Uchiyama, H.2
  • 12
    • 0030482548 scopus 로고    scopus 로고
    • Hypercholesterolemia in the rabbit induced by feeding graded amounts of low-level cholesterol. Methodological considerations regarding individual variability in response to dietary cholesterol and development of lesion type
    • Kolodgie, F. D., Katocs, Jr, A. S., Largis, E. E. et al. (1996) Hypercholesterolemia in the rabbit induced by feeding graded amounts of low-level cholesterol. Methodological considerations regarding individual variability in response to dietary cholesterol and development of lesion type. Arterioscler. Thromb. Vasc. Biol. 16, 1454-1464
    • (1996) Arterioscler. Thromb. Vasc. Biol. , vol.16 , pp. 1454-1464
    • Kolodgie, F.D.1    Katocs A.S., Jr.2    Largis, E.E.3
  • 13
    • 0344429365 scopus 로고    scopus 로고
    • High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase
    • Berard, A. M., Foger, B., Remaley, A. et al. (1997) High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase. Nat. Med. (N.Y.) 3, 744-749
    • (1997) Nat. Med. (N.Y.) , vol.3 , pp. 744-749
    • Berard, A.M.1    Foger, B.2    Remaley, A.3
  • 14
    • 16044372278 scopus 로고    scopus 로고
    • Overexpression of lecithin: Cholesterol acyltransferase in transgenic rabbits prevents diet-induced atherosclerosis
    • Hoeg, J. M., Santamarina-Fojo, S., Berard, A. M. et al. (1996) Overexpression of lecithin: Cholesterol acyltransferase in transgenic rabbits prevents diet-induced atherosclerosis. Proc. Natl. Acad. Sci. U.S.A. 93, 11448-11453
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 11448-11453
    • Hoeg, J.M.1    Santamarina-Fojo, S.2    Berard, A.M.3
  • 15
    • 0036226511 scopus 로고    scopus 로고
    • Effect of HDL, from Japanese white rabbit administered a new cholesteryl ester transfer protein inhibitor JTT-705, on cholesteryl ester accumulation induced by acetylated low density lipoprotein in J774 macrophages
    • Kobayashi, J., Okamoto, H., Otabe, M., Bujo, H. and Saito, Y. (2002) Effect of HDL, from Japanese white rabbit administered a new cholesteryl ester transfer protein inhibitor JTT-705, on cholesteryl ester accumulation induced by acetylated low density lipoprotein in J774 macrophages. Atherosclerosis 162, 131-135
    • (2002) Atherosclerosis , vol.162 , pp. 131-135
    • Kobayashi, J.1    Okamoto, H.2    Otabe, M.3    Bujo, H.4    Saito, Y.5
  • 16
    • 0028784246 scopus 로고
    • Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene
    • Hayek, T., Masucci-Magoulas, L., Jiang, X. et al. (1995) Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene. J. Clin. Invest. 96, 2071-2074
    • (1995) J. Clin. Invest. , vol.96 , pp. 2071-2074
    • Hayek, T.1    Masucci-Magoulas, L.2    Jiang, X.3
  • 17
    • 0025832067 scopus 로고
    • Rabbit hepatic lipase cDNA sequence: Low activity is associated with low messenger RNA levels
    • Warren, R. J., Ebert, D. L., Mitchell, A. and Barter, P. J. (1991) Rabbit hepatic lipase cDNA sequence: Low activity is associated with low messenger RNA levels. J. Lipid Res. 32, 1333-1339
    • (1991) J. Lipid Res. , vol.32 , pp. 1333-1339
    • Warren, R.J.1    Ebert, D.L.2    Mitchell, A.3    Barter, P.J.4
  • 19
    • 0037035459 scopus 로고    scopus 로고
    • Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: A randomized phase II dose-response study
    • de Grooth, G. J., Kuivenhoven, J. A., Stalenhoef, A. F. et al. (2002) Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: A randomized phase II dose-response study. Circulation 105, 2159-2165
    • (2002) Circulation , vol.105 , pp. 2159-2165
    • De Grooth, G.J.1    Kuivenhoven, J.A.2    Stalenhoef, A.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.