Loss of FMRP impaired hippocampal long-term plasticity and spatial learning in rats

Frontiers in Molecular Neuroscience

Volumn 10, Issue , 2017, Pages

  Tian, Yonglu ^a,b   Yang, Chaojuan ^a   Shang, Shujiang ^a   Cai, Yijun ^c   Deng, Xiaofei ^d   Zhang, Jian ^a   Shao, Feng ^b   Zhu, Desheng ^a   Liu, Yunbo ^e   Chen, Guiquan ^f   Liang, Jing ^d   Sun, Qiang ^c   Qiu, Zilong ^c   Zhang, Chen ^a,b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b PEKING UNIVERSITY   (China)

^c INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^d INSTITUTE OF PSYCHOLOGY   (China)

^e INSTITUTE OF LABORATORY ANIMAL SCIENCE   (China)

^f NANJING UNIVERSITY   (China)

Author keywords

FXS; Hippocampus; Intellectual disability; Long term plasticity; Spatial learning

Indexed keywords

FRAGILE X MENTAL RETARDATION 1 PROTEIN; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CRISPR CAS SYSTEM; DIAGNOSTIC PROCEDURE; DNA DETERMINATION; ELECTROPHYSIOLOGY; ELEVATED PLUS MAZE TEST; FMR1 GENE; FRAGILE X SYNDROME; GENE; GENOTYPING TECHNIQUE; HIPPOCAMPUS; HISTOLOGY; HUMAN; INTELLECTUAL IMPAIRMENT; LONG TERM DEPRESSION; MORRIS WATER MAZE TEST; MOTOR ACTIVITY; NERVE CELL PLASTICITY; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SOCIABILITY TEST; SPATIAL LEARNING; SYNAPTIC TRANSMISSION; WESTERN BLOTTING;

EID: 85032335602     PISSN: 16625099     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnmol.2017.00269     Document Type: Article

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