Reduction of BDNF expression in Fmr1 knockout mice worsens cognitive deficits but improves hyperactivity and sensorimotor deficits

Genes, Brain and Behavior

Volumn 11, Issue 5, 2012, Pages 513-523

  Uutela, M ^a   Lindholm, J ^a   Louhivuori, V ^a   Wei, H ^a   Louhivuori, L M ^a   Pertovaara, A ^a   Akerman K ^a   Castren E ^a,b   Castren M L ^a,c  

^a UNIVERSITY OF HELSINKI   (Finland)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c Rinnekoti Foundation Finland   (Finland)

Author keywords

ADHD; Autism; FMRP; Fragile X syndrome; Hippocampus; Hyperactivity; Neurites; Rotarod test; Startle reflex; Water maze learning

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; FRAGILE X MENTAL RETARDATION PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BDNF GENE; CELL SURVIVAL; COGNITIVE DEFECT; CONTROLLED STUDY; FEMALE; FRAGILE X SYNDROME; GENE; GENE DELETION; HIPPOCAMPUS; HYPERACTIVITY; KNOCKOUT MOUSE; MALE; MOUSE; NOCICEPTION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SENSORIMOTOR FUNCTION;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; COGNITION DISORDERS; CONDITIONING (PSYCHOLOGY); FEAR; FRAGILE X MENTAL RETARDATION PROTEIN; GAIT DISORDERS, NEUROLOGIC; HIPPOCAMPUS; HYPERKINESIS; MAZE LEARNING; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; NEURAL STEM CELLS; NEURONS; STARTLE REACTION;

ANIMALIA; MUS;

EID: 84863209197     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/j.1601-183X.2012.00784.x     Document Type: Article

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