The stroke-prone spontaneously hypertensive rat: Still a useful model for post-GWAS genetic studies?

Hypertension Research

Volumn 35, Issue 5, 2012, Pages 477-484

  Nabika, Toru ^a   Ohara, Hiroki ^a   Kato, Norihiro ^b   Isomura, Minoru ^a  

^a SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

Cerebral stroke; Genetics; Hypertension; QTL; SHRSP

Indexed keywords

CD36 ANTIGEN; EPOXIDE HYDROLASE; EPOXIDE HYDROLASE 2; EPOXYICOSATRIENOIC ACID; GLUTATHIONE TRANSFERASE M1; MESSENGER RNA; SODIUM PHOSPHATE COTRANSPORTER 2A; UNCLASSIFIED DRUG;

BLOOD BRAIN BARRIER; BLOOD PRESSURE; BRAIN HEMORRHAGE; BRAIN INFARCTION; CEREBROVASCULAR ACCIDENT; DISEASE PREDISPOSITION; DISEASE SEVERITY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETIC ANALYSIS; GENETIC ASSOCIATION; HUMAN; HYPERTENSION; INCIDENCE; NONHUMAN; PATHOGENESIS; PHENOTYPE; QUANTITATIVE TRAIT LOCUS; RAT; REVIEW; SIMPLE SEQUENCE REPEAT; SINGLE NUCLEOTIDE POLYMORPHISM; STRAIN DIFFERENCE; STROKE PRONE SPONTANEOUSLY HYPERTENSIVE RAT; SYMPATHETIC NERVE; VASODILATATION;

ANIMALS; ANTIGENS, CD36; EPOXIDE HYDROLASES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GLUTATHIONE TRANSFERASE; HUMANS; HYPERTENSION; MALE; MODELS, GENETIC; QUANTITATIVE TRAIT LOCI; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS, TYPE IIA; STROKE; SYMPATHETIC NERVOUS SYSTEM;

EID: 84860726297     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2012.30     Document Type: Review

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