Conserved hippocampal cellular pathophysiology but distinct behavioural deficits in a new rat model of FXS

Human Molecular Genetics

Volumn 24, Issue 21, 2015, Pages 5977-5984

  Till, Sally M ^a,b   Asiminas, Antonis ^a,b   Jackson, Adam D ^b,c   Katsanevaki, Danai ^a,b   Barnes, Stephanie A ^a,b   Osterweil, Emily K ^a,b,d   Bear, Mark F ^d   Chattarji, Sumantra ^a,c,e   Wood, Emma R ^a,b   Wyllie, David J A ^a,b,c   Kind, Peter C ^a,b,c  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c Institute for Stem Cell Biology and Regenerative Medicine   (India)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

FRAGILE X MENTAL RETARDATION PROTEIN; METABOTROPIC RECEPTOR; FMR1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSOCIATIVE MEMORY; ASSOCIATIVE RECOGNITION MEMORY; BEHAVIOR DISORDER; COGNITIVE DEFECT; CONTROLLED STUDY; CYTOPATHOLOGY; DENDRITE; DENDRITIC SPINE; DENSITY; FEMALE; FRAGILE X SYNDROME; GENE DELETION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; KNOCKOUT RAT; LEARNING; LONG TERM DEPRESSION; MALE; MAZE TEST; MEMORY DISORDER; NERVE CELL PLASTICITY; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PYRAMIDAL NERVE CELL; RAT; RAT MODEL; REFERENCE MEMORY; SPATIAL REFERENCE MEMORY; SPECIES DIFFERENCE; TASK PERFORMANCE; ANIMAL; DISEASE MODEL; GENE INACTIVATION; GENETICS; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; FRAGILE X MENTAL RETARDATION PROTEIN; FRAGILE X SYNDROME; GENE KNOCKOUT TECHNIQUES; HIPPOCAMPUS; MALE; MAZE LEARNING; MEMORY DISORDERS; NEURONAL PLASTICITY; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY;

EID: 84946930735     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv299     Document Type: Article

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