메뉴 건너뛰기




Volumn 94, Issue 1, 1999, Pages 185-192

Fragile X mouse: Strain effects of knockout phenotype and evidence suggesting deficient amygdala function

Author keywords

Conditional fear; Fragile X syndrome; Genetics; Long term potentiation; Mouse; Spatial learning

Indexed keywords

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FRAGILE X SYNDROME; GENETICS; INSTRUMENTAL CONDITIONING; KNOCKOUT MOUSE; LONG TERM POTENTIATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DENSITY; SPATIAL DISCRIMINATION; STRAIN DIFFERENCE;

EID: 0032881856     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00285-7     Document Type: Article
Times cited : (266)

References (54)
  • 2
    • 0027377580 scopus 로고
    • FMR1 protein: Conserved RNP family domains and selective RNA binding
    • Ashley C.T., Wilkinson K.D., Reines D., Warren S.T. FMR1 protein: conserved RNP family domains and selective RNA binding. Science. 262:1993;563-566.
    • (1993) Science , vol.262 , pp. 563-566
    • Ashley, C.T.1    Wilkinson, K.D.2    Reines, D.3    Warren, S.T.4
  • 3
    • 0028246435 scopus 로고
    • Fmr1 knockout mice: A model to study fragile X mental retardation
    • The Dutch-Belgian Fragile X Consortium
    • Bakker C.E., The Dutch-Belgian Fragile X Consortium. Fmr1 knockout mice: a model to study fragile X mental retardation. Cell. 78:1994;23-33.
    • (1994) Cell , vol.78 , pp. 23-33
    • Bakker, C.E.1
  • 8
    • 0029816723 scopus 로고    scopus 로고
    • The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals
    • Eberhart D.E., Malter H.E., Feng Y., Warren S.T. The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals. Hum. molec. Genet. 5:1996;1083-1091.
    • (1996) Hum. Molec. Genet. , vol.5 , pp. 1083-1091
    • Eberhart, D.E.1    Malter, H.E.2    Feng, Y.3    Warren, S.T.4
  • 9
    • 0025828597 scopus 로고
    • A strain-specific modifier on mouse chromosome 4 controls the methylation of independent transgene loci
    • Engler P., Haasch D., Pinkert C.A., Doglio L., Glymour M., Brinster R., Storb U. A strain-specific modifier on mouse chromosome 4 controls the methylation of independent transgene loci. Cell. 65:1991;939-947.
    • (1991) Cell , vol.65 , pp. 939-947
    • Engler, P.1    Haasch, D.2    Pinkert, C.A.3    Doglio, L.4    Glymour, M.5    Brinster, R.6    Storb, U.7
  • 10
    • 0031046778 scopus 로고    scopus 로고
    • Fragile X mental retardation protein: Nucleocytoplasmic shuttling and association with somatodendritic ribosomes
    • Feng Y., Gutekunst C.-A., Eberhart D.E., Yi H., Warren S.T., Hersch S.M. Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes. J. Neurosci. 17:1997;1539-1547.
    • (1997) J. Neurosci. , vol.17 , pp. 1539-1547
    • Feng, Y.1    Gutekunst, C.-A.2    Eberhart, D.E.3    Yi, H.4    Warren, S.T.5    Hersch, S.M.6
  • 11
    • 0031310667 scopus 로고    scopus 로고
    • FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association
    • Feng Y., Absher D., Eberhart D.E., Brown V., Malter H.E., Warrren S.T. FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association. Molec. Cell. 1:1997;109-118.
    • (1997) Molec. Cell , vol.1 , pp. 109-118
    • Feng, Y.1    Absher, D.2    Eberhart, D.E.3    Brown, V.4    Malter, H.E.5    Warrren, S.T.6
  • 12
    • 0023908218 scopus 로고
    • Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro
    • Frey U., Krug M., Reymann K.G., Matthies H. Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro. Brain Res. 452:1988;57-65.
    • (1988) Brain Res. , vol.452 , pp. 57-65
    • Frey, U.1    Krug, M.2    Reymann, K.G.3    Matthies, H.4
  • 13
    • 0030064318 scopus 로고    scopus 로고
    • Influence of actinomycin D, an RNA synthesis inhibitor, on long-term potentiation in rat hippocampal neurons in vivo and in vitro
    • Frey U., Frey S., Schollmeier F., Krug M. Influence of actinomycin D, an RNA synthesis inhibitor, on long-term potentiation in rat hippocampal neurons in vivo and in vitro. J. Physiol. 490:1996;703-711.
    • (1996) J. Physiol. , vol.490 , pp. 703-711
    • Frey, U.1    Frey, S.2    Schollmeier, F.3    Krug, M.4
  • 14
    • 0031024891 scopus 로고    scopus 로고
    • Synaptic tagging and long-term potentiation
    • Frey U., Morris R.G.M. Synaptic tagging and long-term potentiation. Science. 385:1997;533-536.
    • (1997) Science , vol.385 , pp. 533-536
    • Frey, U.1    Morris, R.G.M.2
  • 16
    • 0002355832 scopus 로고    scopus 로고
    • Clinical and diagnostic aspects of fragile X syndrome
    • (eds Wells R. D. and Warren S. T.), Academic, San Diego
    • Hagerman R. (1998) Clinical and diagnostic aspects of fragile X syndrome. In Genetic Instabilities and Hereditary Neurological Diseases (eds Wells R. D. and Warren S. T.), pp. 15-25. Academic, San Diego.
    • (1998) In Genetic Instabilities and Hereditary Neurological Diseases , pp. 15-25
    • Hagerman, R.1
  • 18
    • 0027397928 scopus 로고
    • Tissue specific expression of FMR1 provides evidence for a functional role in fragile X syndrome
    • Hinds H.L., Ashley C.T., Nelson D.L., Warren S.T., Housman D.E., Shalling M. Tissue specific expression of FMR1 provides evidence for a functional role in fragile X syndrome. Nature Genet. 3:1993;36-43.
    • (1993) Nature Genet. , vol.3 , pp. 36-43
    • Hinds, H.L.1    Ashley, C.T.2    Nelson, D.L.3    Warren, S.T.4    Housman, D.E.5    Shalling, M.6
  • 19
    • 0001299954 scopus 로고    scopus 로고
    • FMR1 and mutations in fragile X syndrome: Molecular biology, biochemistry and genetics
    • (eds Wells R. D. and Warren S. T.), Academic, San Diego
    • Imbert G., Feng Y., Nelson D. L., Warren S. T. and Mandel J.-L. (1998) FMR1 and mutations in fragile X syndrome: molecular biology, biochemistry and genetics. In Genetic Instabilities and Hereditary Neurological Diseases (eds Wells R. D. and Warren S. T.), pp. 27-53. Academic, San Diego.
    • (1998) In Genetic Instabilities and Hereditary Neurological Diseases , pp. 27-53
    • Imbert, G.1    Feng, Y.2    Nelson, D.L.3    Warren, S.T.4    Mandel, J.-L.5
  • 22
    • 0030059545 scopus 로고    scopus 로고
    • The fragile X mental retardation protein is associated with ribosomes
    • Khandjian E.W., Corbin F., Woerly S., Rousseau F. The fragile X mental retardation protein is associated with ribosomes. Nature Genet. 12:1996;91-93.
    • (1996) Nature Genet. , vol.12 , pp. 91-93
    • Khandjian, E.W.1    Corbin, F.2    Woerly, S.3    Rousseau, F.4
  • 23
    • 0027723577 scopus 로고
    • Effects of amygdala, hippocampus and periaqueductal gray lesions on short- And long-term contextual fear
    • Kim J.J., Rison R.A., Fanselow M.S. Effects of amygdala, hippocampus and periaqueductal gray lesions on short- and long-term contextual fear. Behav. Neurosci. 107:1993;1093-1098.
    • (1993) Behav. Neurosci. , vol.107 , pp. 1093-1098
    • Kim, J.J.1    Rison, R.A.2    Fanselow, M.S.3
  • 24
    • 0031777166 scopus 로고    scopus 로고
    • Induction of gut mucosal immune responses: Importance of genetic background and Th1/Th2 cross-regulation
    • Kjerrulf M., Grdic D., Kopf M., Lycke N. Induction of gut mucosal immune responses: importance of genetic background and Th1/Th2 cross-regulation. Scand. J. Immun. 47:1998;401-407.
    • (1998) Scand. J. Immun. , vol.47 , pp. 401-407
    • Kjerrulf, M.1    Grdic, D.2    Kopf, M.3    Lycke, N.4
  • 27
    • 0022483381 scopus 로고
    • Induction of synaptic potentiation in hippocampus by patterned stimulation involves two events
    • Larson J., Lynch G. Induction of synaptic potentiation in hippocampus by patterned stimulation involves two events. Science. 232:1986;985-988.
    • (1986) Science , vol.232 , pp. 985-988
    • Larson, J.1    Lynch, G.2
  • 28
    • 0031782695 scopus 로고    scopus 로고
    • Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene
    • LeCouter J., Kablar B., Hardy W.R., Ying C., Megeney L.A., May L.L., Rudnicki M.A. Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene. Molec. cell. Biol. 18:1998;7455-7465.
    • (1998) Molec. Cell. Biol. , vol.18 , pp. 7455-7465
    • Lecouter, J.1    Kablar, B.2    Hardy, W.R.3    Ying, C.4    Megeney, L.A.5    May, L.L.6    Rudnicki, M.A.7
  • 29
    • 0029107645 scopus 로고
    • Emotion: Clues from the brain
    • LeDoux J. Emotion: clues from the brain. A. Rev. Psychol. 46:1995;209-235.
    • (1995) A. Rev. Psychol. , vol.46 , pp. 209-235
    • Ledoux, J.1
  • 30
    • 0028295792 scopus 로고
    • Cognitive functioning and information processing of adult mentally retarded men with fragile X syndrome
    • Maes B., Fryns J.P., Vanwalleghem M., Vandenberghe H. Cognitive functioning and information processing of adult mentally retarded men with fragile X syndrome. Am. J. Med. Genet. 50:1994;190-200.
    • (1994) Am. J. Med. Genet. , vol.50 , pp. 190-200
    • Maes, B.1    Fryns, J.P.2    Vanwalleghem, M.3    Vandenberghe, H.4
  • 31
    • 0029066116 scopus 로고
    • CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP
    • Mayford M., Wang J., Kandel E.R., O'Dell T.J. CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP. Cell. 81:1995;891-904.
    • (1995) Cell , vol.81 , pp. 891-904
    • Mayford, M.1    Wang, J.2    Kandel, E.R.3    O'Dell, T.J.4
  • 32
    • 0032564337 scopus 로고    scopus 로고
    • Effect of reduced myristolated alanine-rich C kinase substrate expression on hippocampal mossy fiber development and spatial learning in mutant mice: Transgenic rescue and interactions with gene background
    • McNamara R.K., Stumpo D.J., Morel L.M., Lewis M.H., Wakeland E.K., Blackshear P.J., Lenox R.H. Effect of reduced myristolated alanine-rich C kinase substrate expression on hippocampal mossy fiber development and spatial learning in mutant mice: transgenic rescue and interactions with gene background. Proc. natn. Acad. Sci. U.S.A. 95:1998;14,517-14,522.
    • (1998) Proc. Natn. Acad. Sci. U.S.A. , vol.95 , pp. 14
    • McNamara, R.K.1    Stumpo, D.J.2    Morel, L.M.3    Lewis, M.H.4    Wakeland, E.K.5    Blackshear, P.J.6    Lenox, R.H.7
  • 33
    • 0005535917 scopus 로고
    • Spatial localization does not require the presence of local cues
    • Morris R.G.M. Spatial localization does not require the presence of local cues. Learn. Motiv. 12:1981;239-260.
    • (1981) Learn. Motiv. , vol.12 , pp. 239-260
    • Morris, R.G.M.1
  • 35
    • 0028038057 scopus 로고
    • Requirement of a critical period of transcription for induction of a late phase of LTP
    • Nguyen P.V., Abel T., Kandel E.R. Requirement of a critical period of transcription for induction of a late phase of LTP. Science. 265:1994;1104-1107.
    • (1994) Science , vol.265 , pp. 1104-1107
    • Nguyen, P.V.1    Abel, T.2    Kandel, E.R.3
  • 38
    • 0024831236 scopus 로고
    • Inhibition of protein synthesis in the dentate gyrus, but not the entorhinal cortex, blocks maintenance of long-term potentiation in rats
    • Otani S., Abraham W.C. Inhibition of protein synthesis in the dentate gyrus, but not the entorhinal cortex, blocks maintenance of long-term potentiation in rats. Neurosci. Lett. 106:1989;175-180.
    • (1989) Neurosci. Lett. , vol.106 , pp. 175-180
    • Otani, S.1    Abraham, W.C.2
  • 39
    • 0030740829 scopus 로고    scopus 로고
    • Assessment of learning by the Morris water task and fear conditioning in inbred mouse strains and F1 hybrids: Implications of genetic background for single gene mutations and quantitative trait loci analysis
    • Owen E.H., Logue S.F., Rasmussen D.L., Wehner J.M. Assessment of learning by the Morris water task and fear conditioning in inbred mouse strains and F1 hybrids: implications of genetic background for single gene mutations and quantitative trait loci analysis. Neuroscience. 80:1997;1087-1099.
    • (1997) Neuroscience , vol.80 , pp. 1087-1099
    • Owen, E.H.1    Logue, S.F.2    Rasmussen, D.L.3    Wehner, J.M.4
  • 40
    • 0028016082 scopus 로고
    • DBA/2 and C57BL/6 mice differ in contextual fear but not auditory fear conditioning
    • Paylor R., Tracy R., Wehner J., Rudy J.W. DBA/2 and C57BL/6 mice differ in contextual fear but not auditory fear conditioning. Behav. Neurosci. 108:1994;810-817.
    • (1994) Behav. Neurosci. , vol.108 , pp. 810-817
    • Paylor, R.1    Tracy, R.2    Wehner, J.3    Rudy, J.W.4
  • 41
    • 0026635574 scopus 로고
    • Differential contribution of the amygdala and hippocampus to cued and contextual fear conditioning
    • Phillips R.G., LeDoux J.E. Differential contribution of the amygdala and hippocampus to cued and contextual fear conditioning. Behav. Neurosci. 106:1992;274-285.
    • (1992) Behav. Neurosci. , vol.106 , pp. 274-285
    • Phillips, R.G.1    Ledoux, J.E.2
  • 43
    • 0026649793 scopus 로고
    • Behavioral phenotype of fragile X syndrome: DSM-III-R autistic behavior in male children
    • Reiss A., Freund L. Behavioral phenotype of fragile X syndrome: DSM-III-R autistic behavior in male children. Am. J. Med. Genet. 43:1992;35-46.
    • (1992) Am. J. Med. Genet. , vol.43 , pp. 35-46
    • Reiss, A.1    Freund, L.2
  • 44
    • 0026637195 scopus 로고
    • Deficient hippocampal long-term potentiation in calcium-calmodulin kinase II mutant mice
    • Silva A.J., Stevens C.F., Tonegawa S., Wang Y. Deficient hippocampal long-term potentiation in calcium-calmodulin kinase II mutant mice. Science. 257:1992;201-206.
    • (1992) Science , vol.257 , pp. 201-206
    • Silva, A.J.1    Stevens, C.F.2    Tonegawa, S.3    Wang, Y.4
  • 46
    • 0023485206 scopus 로고
    • Stable hippocampal long-term potentiation elicited by "theta" pattern stimulation
    • Stäubli U., Lynch G. Stable hippocampal long-term potentiation elicited by "theta" pattern stimulation. Brain Res. 435:1987;227-234.
    • (1987) Brain Res. , vol.435 , pp. 227-234
    • Stäubli, U.1    Lynch, G.2
  • 49
    • 0031153983 scopus 로고    scopus 로고
    • Genealogy of the 129 strains: 129/SvJ is a contaminated inbred strain
    • Threadgill D.W., Yee D., Matin A., Nadeau J.H., Magnuson T. Genealogy of the 129 strains: 129/SvJ is a contaminated inbred strain. Mamm. Genome. 8:1997;390-393.
    • (1997) Mamm. Genome , vol.8 , pp. 390-393
    • Threadgill, D.W.1    Yee, D.2    Matin, A.3    Nadeau, J.H.4    Magnuson, T.5
  • 54
    • 0024600340 scopus 로고
    • Short-term synaptic plasticity
    • Zucker R.S. Short-term synaptic plasticity. A. Rev. Neurosci. 12:1989;13-31.
    • (1989) A. Rev. Neurosci. , vol.12 , pp. 13-31
    • Zucker, R.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.