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Volumn 1207, Issue , 2010, Pages 89-96

Effect of intravenous administration of dipyridamole in a rat model of chronic cerebral ischemia

Author keywords

Chronic ischemia; Cognition tests; Dipyridamole; Neurological deficit; Two vessel occlusion

Indexed keywords

DIPYRIDAMOLE; NEUROPROTECTIVE AGENT;

EID: 78149263840     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2010.05732.x     Document Type: Article
Times cited : (33)

References (78)
  • 2
    • 0025944890 scopus 로고
    • Experimental basis of multi-infarct dementia: memory impairments in rodent models of ischemia
    • Naritomi, H. 1991. Experimental basis of multi-infarct dementia: memory impairments in rodent models of ischemia. Alzheimer Dis. Assoc. Disord. 5: 103-111.
    • (1991) Alzheimer Dis. Assoc. Disord. , vol.5 , pp. 103-111
    • Naritomi, H.1
  • 3
    • 33744989966 scopus 로고    scopus 로고
    • Progressive expression of vascular endothelial growth factor (VEGF) and angiogenesis after chronic ischemic hypoperfusion in rat
    • Ohtaki, H. et al. 2006. Progressive expression of vascular endothelial growth factor (VEGF) and angiogenesis after chronic ischemic hypoperfusion in rat. Acta Neurochir. Suppl. 96: 283-287.
    • (2006) Acta Neurochir. Suppl. , vol.96 , pp. 283-287
    • Ohtaki, H.1
  • 4
    • 34250832745 scopus 로고    scopus 로고
    • AT1 receptor blocker candesartaninduced attenuation of brain injury of rats subjected to chronic cerebral hypoperfusion
    • Ozacmak,VH.et al. 2007.AT1 receptor blocker candesartaninduced attenuation of brain injury of rats subjected to chronic cerebral hypoperfusion. Neurochem. Res. 32: 1314- 1321.
    • (2007) Neurochem. Res. , vol.32 , pp. 1314-1321
    • Ozacmak, V.H.1
  • 5
    • 0037111169 scopus 로고    scopus 로고
    • Cognitive impairment and chronic cerebral hypoperfusion: what can be learned from experimental models
    • Sarti, C. et al. 2002a. Cognitive impairment and chronic cerebral hypoperfusion: what can be learned from experimental models. J. Neurol. Sci. 203-204: 263-266.
    • (2002) J. Neurol. Sci. , vol.203-204 , pp. 263-266
    • Sarti, C.1
  • 6
    • 0028075147 scopus 로고
    • A chronic physiological rat model of dementia
    • de la Torre, J.C. & T. Fortin. 1994. A chronic physiological rat model of dementia. Behav. Brain Res. 63: 35-40.
    • (1994) Behav. Brain Res , vol.63 , pp. 35-40
    • de la Torre, J.C.1    Fortin, T.2
  • 7
    • 0026625139 scopus 로고
    • Chronic cerebrovascular insufficiency induces dementia-like deficits in aged rats
    • de la Torre, J.C. et al. 1992. Chronic cerebrovascular insufficiency induces dementia-like deficits in aged rats. Brain Res. 582: 186-195.
    • (1992) Brain Res , vol.582 , pp. 186-195
    • de la Torre, J.C.1
  • 8
    • 0024994784 scopus 로고
    • Learning impairment andmicrotubuleassociated protein 2 decrease in gerbils under chronic cerebral hypoperfusion
    • Kudo, T. et al. 1990. Learning impairment andmicrotubuleassociated protein 2 decrease in gerbils under chronic cerebral hypoperfusion. Stroke 21: 1205-1209.
    • (1990) Stroke , vol.21 , pp. 1205-1209
    • Kudo, T.1
  • 9
    • 0028141757 scopus 로고
    • Progressive cognitive impairment following chronic cerebral hypoperfusion induced by permanent occlusion of bilateral carotid arteries in rats
    • Ni, J. et al. 1994. Progressive cognitive impairment following chronic cerebral hypoperfusion induced by permanent occlusion of bilateral carotid arteries in rats. Brain Res. 653: 231-236.
    • (1994) Brain Res , vol.653 , pp. 231-236
    • Ni, J.1
  • 10
    • 0030825440 scopus 로고    scopus 로고
    • Chronic cerebral hypoperfusion by permanent internal carotid ligation produces learning impairment without brain damage in rats
    • Ohta, H. et al. 1997. Chronic cerebral hypoperfusion by permanent internal carotid ligation produces learning impairment without brain damage in rats. Neuroscience 79: 1039-1050.
    • (1997) Neuroscience , vol.79 , pp. 1039-1050
    • Ohta, H.1
  • 11
    • 0030021780 scopus 로고    scopus 로고
    • Chronic reduction of cerebral blood flowin the adult rat: late-emergingCA1cell loss andmemory dysfunction
    • Pappas, B.A. et al. 1996. Chronic reduction of cerebral blood flowin the adult rat: late-emergingCA1cell loss andmemory dysfunction. Brain Res. 708: 50-58.
    • (1996) Brain Res , vol.708 , pp. 50-58
    • Pappas, B.A.1
  • 12
    • 0037126173 scopus 로고    scopus 로고
    • Persistent impairment of gait performances andworkingmemory after bilateral commoncarotid artery occlusion inthe adultWistar rat
    • Sarti, C. et al. 2002b. Persistent impairment of gait performances andworkingmemory after bilateral commoncarotid artery occlusion inthe adultWistar rat. Behav.BrainRes. 136: 13-20.
    • (2002) Behav. BrainRes. , vol.136 , pp. 13-20
    • Sarti, C.1
  • 13
    • 31844454079 scopus 로고    scopus 로고
    • Minocycline attenuates white matter damage in a rat model of chronic cerebral hypoperfusion
    • Cho, K.O. et al. 2006. Minocycline attenuates white matter damage in a rat model of chronic cerebral hypoperfusion. J. Neurosci. Res. 83: 285-291.
    • (2006) J. Neurosci. Res. , vol.83 , pp. 285-291
    • Cho, K.O.1
  • 14
    • 0242353022 scopus 로고    scopus 로고
    • Ibudilast, a phosphodiesterase inhibitor, protects against white matter damage under chronic cerebral hypoperfusion in the rat
    • Wakita, H. et al. 2003. Ibudilast, a phosphodiesterase inhibitor, protects against white matter damage under chronic cerebral hypoperfusion in the rat. Brain Res. 992: 53-59.
    • (2003) Brain Res , vol.992 , pp. 53-59
    • Wakita, H.1
  • 15
    • 33947646259 scopus 로고    scopus 로고
    • Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseases
    • Farkas, E., P.G. Luiten & F. Bari. 2007. Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseases. Brain Res. Rev. 54: 162-180.
    • (2007) Brain Res. Rev , vol.54 , pp. 162-180
    • Farkas, E.1    Luiten, P.G.2    Bari, F.3
  • 16
    • 33947536948 scopus 로고    scopus 로고
    • Baicalein improves cognitive deficits induced by chronic cerebral hypoperfusion in rats
    • Liu, C. et al. 2007. Baicalein improves cognitive deficits induced by chronic cerebral hypoperfusion in rats. Pharmacol. Biochem. Behav. 86: 423-430.
    • (2007) Pharmacol. Biochem. Behav. , vol.86 , pp. 423-430
    • Liu, C.1
  • 17
    • 0142043020 scopus 로고    scopus 로고
    • Reperfusion enhances nitrotyrosine formation in rat focal cerebral ischemia
    • Takizawa, S. et al. 2003. Reperfusion enhances nitrotyrosine formation in rat focal cerebral ischemia. J. Stroke Cerebrovasc. Dis. 12: 196-200.
    • (2003) J. Stroke Cerebrovasc. Dis. , vol.12 , pp. 196-200
    • Takizawa, S.1
  • 18
    • 20444407153 scopus 로고    scopus 로고
    • Cognitive consequences of thalamic, basal ganglia, and deep white matter lacunes in brain aging and dementia
    • Gold, G. et al. 2005. Cognitive consequences of thalamic, basal ganglia, and deep white matter lacunes in brain aging and dementia. Stroke 36: 1184-1188.
    • (2005) Stroke , vol.36 , pp. 1184-1188
    • Gold, G.1
  • 19
    • 77649185157 scopus 로고    scopus 로고
    • Changes in pro-oxidant and antioxidant enzyme levels during cerebral hypoperfusion in rats
    • Mracskó, E. et al. 2010. Changes in pro-oxidant and antioxidant enzyme levels during cerebral hypoperfusion in rats. Brain Res. 1321: 13-19.
    • (2010) Brain Res , vol.1321 , pp. 13-19
    • Mracskó, E.1
  • 20
    • 76649110556 scopus 로고    scopus 로고
    • Minocycline reduces astrocytic reactivation and neuroinflammation in the hippocampus of a vascular cognitive impairment rat model
    • Cai, Z.Y., Y. Yan&R. Chen. 2010.Minocycline reduces astrocytic reactivation and neuroinflammation in the hippocampus of a vascular cognitive impairment rat model. Neurosci. Bull. 26: 28-36.
    • (2010) Neurosci. Bull. , vol.26 , pp. 28-36
    • Cai, Z.Y.1    Yan, Y.2    Chen, R.3
  • 21
    • 76549112494 scopus 로고    scopus 로고
    • Huperzine a improves chronic inflammation and cognitive decline in rats with cerebral hypoperfusion
    • Wang, J., H.Y. Zhang & X.C. Tang. 2010. Huperzine a improves chronic inflammation and cognitive decline in rats with cerebral hypoperfusion. J. Neurosci. Res. 88: 807- 815.
    • (2010) J. Neurosci. Res. , vol.88 , pp. 807-815
    • Wang, J.1    Zhang, H.Y.2    Tang, X.C.3
  • 22
    • 16644398901 scopus 로고    scopus 로고
    • Diazoxide and dimethyl sulphoxide alleviate experimental cerebral hypoperfusion-induced white matter injury in the rat brain
    • Farkas, E. et al. 2005. Diazoxide and dimethyl sulphoxide alleviate experimental cerebral hypoperfusion-induced white matter injury in the rat brain. Neurosci. Lett. 373: 195-199.
    • (2005) Neurosci. Lett. , vol.373 , pp. 195-199
    • Farkas, E.1
  • 23
    • 58149389909 scopus 로고    scopus 로고
    • Astroglial and cognitive effects of chronic cerebral hypoperfusion in the rat
    • Vicente, E. et al. 2009. Astroglial and cognitive effects of chronic cerebral hypoperfusion in the rat. Brain Res. 1251: 204-212.
    • (2009) Brain Res , vol.1251 , pp. 204-212
    • Vicente, E.1
  • 24
    • 33745153095 scopus 로고    scopus 로고
    • Cilostazol protects against brain white matter damage and cognitive impairment in a rat model of chronic cerebral hypoperfusion
    • Watanabe, T. et al. 2006. Cilostazol protects against brain white matter damage and cognitive impairment in a rat model of chronic cerebral hypoperfusion. Stroke 37: 1539- 1545.
    • (2006) Stroke , vol.37 , pp. 1539-1545
    • Watanabe, T.1
  • 25
    • 77952674708 scopus 로고    scopus 로고
    • Osthole improves chronic cerebral hypoperfusion induced cognitive deficits and neuronal damage in hippocampus
    • Ji,H.J. et al. 2010. Osthole improves chronic cerebral hypoperfusion induced cognitive deficits and neuronal damage in hippocampus. Eur. J. Pharmacol. 636: 96-101.
    • (2010) Eur. J. Pharmacol. , vol.636 , pp. 96-101
    • Ji, H.J.1
  • 26
    • 0032712051 scopus 로고    scopus 로고
    • Chronic dipyridamole therapy produces sustained protection against cardiac ischemiareperfusion injury
    • Figueredo, V.M. et al. 1999. Chronic dipyridamole therapy produces sustained protection against cardiac ischemiareperfusion injury. Am. J. Physiol. 277: H2091-H2097.
    • (1999) Am. J. Physiol. , vol.277
    • Figueredo, V.M.1
  • 27
    • 21844439777 scopus 로고    scopus 로고
    • Oral therapywith dipyridamole limits ischemia-reperfusion injury in humans
    • Riksen,N.P. et al. 2005. Oral therapywith dipyridamole limits ischemia-reperfusion injury in humans. Clin. Pharmacol. Ther. 78: 52-59.
    • (2005) Clin. Pharmacol. Ther. , vol.78 , pp. 52-59
    • Riksen, N.P.1
  • 28
    • 10544237133 scopus 로고
    • Mode of action of adenosine-potentiating vasodilators
    • R.M. Berne, T.W. Frall & R. Rubio, Eds.. Nijhoff. Boston
    • Henrichs, K.J., H. Matsuoka & W. Schaper. 1983. Mode of action of adenosine-potentiating vasodilators. In: Regulatory Function of Adenosine. R.M. Berne, T.W. Frall & R. Rubio, Eds.: 517-523. Nijhoff. Boston.
    • (1983) Regulatory Function of Adenosine , pp. 517-523
    • Henrichs, K.J.1    Matsuoka, H.2    Schaper, W.3
  • 29
    • 20344374724 scopus 로고    scopus 로고
    • Adenosine and adenine nucleotides as regulators of cerebral blood flow: roles of acidosis, cell swelling, and KATP channels
    • Phillis, J.W. 2004. Adenosine and adenine nucleotides as regulators of cerebral blood flow: roles of acidosis, cell swelling, and KATP channels. Crit. Rev. Neurobiol. 16: 237-270.
    • (2004) Crit. Rev. Neurobiol. , vol.16 , pp. 237-270
    • Phillis, J.W.1
  • 30
    • 77950520471 scopus 로고    scopus 로고
    • Role of adenosine A2 receptors in regulation of cerebral blood flow during induced hypotension
    • Kusano, Y. et al. 2010. Role of adenosine A2 receptors in regulation of cerebral blood flow during induced hypotension. J. Cereb. Blood Flow Metab. 30: 808-815.
    • (2010) J. Cereb. Blood Flow Metab. , vol.30 , pp. 808-815
    • Kusano, Y.1
  • 31
    • 0040157914 scopus 로고
    • Inhibition of the aggregation of blood platelets by substances related to adenosine diphosphate
    • Born, G.V.R. & M.J. Cross. 1963. Inhibition of the aggregation of blood platelets by substances related to adenosine diphosphate. J. Physiol. 166: 29P-30P.
    • (1963) J. Physiol. , vol.166
    • Born, G.V.R.1    Cross, M.J.2
  • 32
    • 0022919535 scopus 로고
    • Inhibition of platelet aggregation in whole blood by dipyridamole and aspirin
    • Heptinstall, S. et al. 1986. Inhibition of platelet aggregation in whole blood by dipyridamole and aspirin. Thromb. Res. 42: 215-223.
    • (1986) Thromb. Res. , vol.42 , pp. 215-223
    • Heptinstall, S.1
  • 33
    • 0014403961 scopus 로고
    • Effect of a pyrimido-pyrimidine compound on platelet behaviour in vitro and in vivo
    • Elkeles, R.S. et al. 1968. Effect of a pyrimido-pyrimidine compound on platelet behaviour in vitro and in vivo. Lancet. 2: 751-754.
    • (1968) Lancet , vol.2 , pp. 751-754
    • Elkeles, R.S.1
  • 34
    • 0018864096 scopus 로고
    • Anticoagulant vs anti-platelet therapy as prophylactic against cerebral infarction in transient ischemic attacks
    • Olsson, J.E. et al. 1980. Anticoagulant vs anti-platelet therapy as prophylactic against cerebral infarction in transient ischemic attacks. Stroke 11: 4-9.
    • (1980) Stroke , vol.11 , pp. 4-9
    • Olsson, J.E.1
  • 35
    • 0020679929 scopus 로고
    • " AICLA" controlled trial of aspirin and dipyridamole in the secondary prevention of atherothrombotic cerebral ischemia
    • Bousser, M.G. et al. 1983. " AICLA" controlled trial of aspirin and dipyridamole in the secondary prevention of atherothrombotic cerebral ischemia. Stroke 14: 5-14.
    • (1983) Stroke , vol.14 , pp. 5-14
    • Bousser, M.G.1
  • 36
    • 0021848170 scopus 로고
    • American-Canadian Co-Operative Study Group. Persantine aspirin trial in cerebral ischemia. Part II: Endpoint results
    • American-Canadian Co-Operative Study Group. 1985. Persantine aspirin trial in cerebral ischemia. Part II: Endpoint results. Stroke 16: 406-415.
    • (1985) Stroke , vol.16 , pp. 406-415
  • 37
    • 33646596912 scopus 로고    scopus 로고
    • The ESPRIT Study Group. Aspirin plus dipyridamole versus aspirin alone after cerebral ischemia of arterial origin (ESPRIT): randomised controlled trial
    • The ESPRIT Study Group. 2006. Aspirin plus dipyridamole versus aspirin alone after cerebral ischemia of arterial origin (ESPRIT): randomised controlled trial. Lancet 367: 1665- 1673.
    • (2006) Lancet , vol.367 , pp. 1665-1673
  • 38
    • 0030864167 scopus 로고    scopus 로고
    • European stroke prevention study 2 dipyridamole and acetylsalicylic acid in the secondary prevention of stroke
    • Forbes, C.D. 1997. European stroke prevention study 2: dipyridamole and acetylsalicylic acid in the secondary prevention of stroke. Int. J. Clin. Pract. 51: 205-208.
    • (1997) Int. J. Clin. Pract. , vol.51 , pp. 205-208
    • Forbes, C.D.1
  • 39
    • 33749047067 scopus 로고    scopus 로고
    • Comparison between aspirin combined with dipyridamole versus aspirin alone within 48 hours after ischemic stroke event for prevention of recurrent stroke and improvement of neurological function: a preliminary study
    • Chairangsarit, P. et al. 2005. Comparison between aspirin combined with dipyridamole versus aspirin alone within 48 hours after ischemic stroke event for prevention of recurrent stroke and improvement of neurological function: a preliminary study. J. Med. Assoc. Thai. 88: S148-S154.
    • (2005) J. Med. Assoc. Thai. , vol.88
    • Chairangsarit, P.1
  • 40
    • 33750942726 scopus 로고    scopus 로고
    • How much esprit is in ESPRIT
    • Diener, H.C. 2006. How much esprit is in ESPRIT? Stroke 37: 2856-2857.
    • (2006) Stroke , vol.37 , pp. 2856-2857
    • Diener, H.C.1
  • 41
    • 33645737200 scopus 로고    scopus 로고
    • Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline
    • Sacco, R.L. et al. 2006. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline. Circulation 113: e409-e449.
    • (2006) Circulation , vol.113
    • Sacco, R.L.1
  • 42
    • 0037335810 scopus 로고    scopus 로고
    • Dipyridamole enhances NO/cGMPmediated vasodilator-stimulated phosphoprotein phosphorylation and signaling in human platelets: in vitro and in vivo/ex vivo studies
    • Aktas, B. et al. 2003. Dipyridamole enhances NO/cGMPmediated vasodilator-stimulated phosphoprotein phosphorylation and signaling in human platelets: in vitro and in vivo/ex vivo studies. Stroke 34: 764-769.
    • (2003) Stroke , vol.34 , pp. 764-769
    • Aktas, B.1
  • 43
    • 0006016786 scopus 로고    scopus 로고
    • Dipyridamole
    • Ed. Academic Press. London
    • Eisert, W. 2002. Dipyridamole. In Platelets. A. Michelson, Ed.: 803-815. Academic Press. London.
    • (2002) Platelets. A. Michelson , pp. 803-815
    • Eisert, W.1
  • 44
    • 0347899378 scopus 로고    scopus 로고
    • Dipyridamole is neuroprotective for cultured rat embryonic cortical neurons
    • Blake, A.D. 2004. Dipyridamole is neuroprotective for cultured rat embryonic cortical neurons. Biochem. Biophys. Res. Commun. 314: 501-504.
    • (2004) Biochem. Biophys. Res. Commun. , vol.314 , pp. 501-504
    • Blake, A.D.1
  • 45
    • 0028896760 scopus 로고
    • A potent chain-breaking antioxidant activity of the cardiovascular drug dipyridamole
    • Iuliano, L. et al. 1995. A potent chain-breaking antioxidant activity of the cardiovascular drug dipyridamole. Free Radic. Biol. Med. 18: 239-247.
    • (1995) Free Radic. Biol. Med. , vol.18 , pp. 239-247
    • Iuliano, L.1
  • 46
    • 0345307304 scopus 로고    scopus 로고
    • Antioxidant properties of dipyridamole as assessed by chemiluminescence
    • Vargas, F. et al. 2003.Antioxidant properties of dipyridamole as assessed by chemiluminescence. Pharmazie 58: 817-823.
    • (2003) Pharmazie , vol.58 , pp. 817-823
    • Vargas, F.1
  • 47
    • 33847160003 scopus 로고    scopus 로고
    • TNF- alpha and IL-8 in acute stroke and the modulation of these cytokines by antiplatelet agents
    • Al-Bahrani, A. et al. 2007. TNF-alpha and IL-8 in acute stroke and the modulation of these cytokines by antiplatelet agents. Curr. Neurovasc. Res. 4: 31-37.
    • (2007) Curr. Neurovasc. Res. , vol.4 , pp. 31-37
    • Al-Bahrani, A.1
  • 48
    • 13444281904 scopus 로고    scopus 로고
    • Dipyridamole selectively inhibits inflammatory gene expression in platelet-monocyte aggregates
    • Weyrich, A.S. et al. 2005. Dipyridamole selectively inhibits inflammatory gene expression in platelet-monocyte aggregates. Circulation 111: 633-642.
    • (2005) Circulation , vol.111 , pp. 633-642
    • Weyrich, A.S.1
  • 49
    • 33745127751 scopus 로고    scopus 로고
    • Dipyridamole activation of mitogenactivated protein kinase phosphatase-1 mediates inhibition of lipopolysaccharide-induced cyclooxygenase-2 expression in RAW264.7 cells
    • Chen, T.H. et al. 2006. Dipyridamole activation of mitogenactivated protein kinase phosphatase-1 mediates inhibition of lipopolysaccharide-induced cyclooxygenase-2 expression in RAW264.7 cells. Eur. J. Pharmacol. 541: 138-146.
    • (2006) Eur. J. Pharmacol. , vol.541 , pp. 138-146
    • Chen, T.H.1
  • 50
    • 65749106380 scopus 로고    scopus 로고
    • Effects of monocyte chemoattractant protein 1 on blood-borne cell recruitment after transient focal cerebral ischemia in mice
    • Schilling, M. et al. 2009. Effects of monocyte chemoattractant protein 1 on blood-borne cell recruitment after transient focal cerebral ischemia in mice. Neuroscience 161: 806-812.
    • (2009) Neuroscience , vol.161 , pp. 806-812
    • Schilling, M.1
  • 51
    • 0036194439 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 deficiency is protective in a murine stroke model
    • Hughes, P.M. et al. 2002. Monocyte chemoattractant protein-1 deficiency is protective in a murine stroke model. J. Cereb. Blood Flow Metab. 22: 308-317.
    • (2002) J. Cereb. Blood Flow Metab. , vol.22 , pp. 308-317
    • Hughes, P.M.1
  • 52
    • 34247874753 scopus 로고    scopus 로고
    • Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice
    • Dimitrijevic, O.B. et al. 2007. Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice. Stroke 38: 1345-1353.
    • (2007) Stroke , vol.38 , pp. 1345-1353
    • Dimitrijevic, O.B.1
  • 53
    • 43849097254 scopus 로고    scopus 로고
    • Dipyridamole, cerebrovascular disease, and the vasculature
    • Chakrabarti, S. & J.E. Freedmans 2008. Dipyridamole, cerebrovascular disease, and the vasculature. Vascul. Pharmacol. 48: 143-149.
    • (2008) Vascul. Pharmacol. , vol.48 , pp. 143-149
    • Chakrabarti, S.1    Freedmans, J.E.2
  • 54
    • 76749112482 scopus 로고    scopus 로고
    • Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/ nitric oxide-dependent pathway
    • Venkatesh, P.K. et al. 2010. Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/ nitric oxide-dependent pathway. Cardiovasc. Res. 85: 661-670.
    • (2010) Cardiovasc. Res. , vol.85 , pp. 661-670
    • Venkatesh, P.K.1
  • 55
    • 76349124646 scopus 로고    scopus 로고
    • Adenosine up-regulates vascular endothelial growth factor in human macrophages
    • Ernens, I. et al. 2010. Adenosine up-regulates vascular endothelial growth factor in human macrophages. Biochem. Biophys. Res. Commun. 392: 351-356.
    • (2010) Biochem. Biophys. Res. Commun. , vol.392 , pp. 351-356
    • Ernens, I.1
  • 56
    • 77953493495 scopus 로고    scopus 로고
    • Dipyridamole suppresses high glucose-induced osteopontin secretion and mRNA expression in rat aortic smooth muscle cells
    • Hsieh, M.S. et al. 2010. Dipyridamole suppresses high glucose-induced osteopontin secretion and mRNA expression in rat aortic smooth muscle cells. Circ. J. 74: 1242- 1250.
    • (2010) Circ. J. , vol.74 , pp. 1242-1250
    • Hsieh, M.S.1
  • 57
    • 0033038246 scopus 로고    scopus 로고
    • Inhibition by dipyridamole of neutrophil adhesion to vascular endothelium during coronary bypass surgery
    • Chello, M. et al. 1999. Inhibition by dipyridamole of neutrophil adhesion to vascular endothelium during coronary bypass surgery. Ann. Thorac. Surg. 67: 1277-1282.
    • (1999) Ann. Thorac. Surg. , vol.67 , pp. 1277-1282
    • Chello, M.1
  • 58
    • 0022974995 scopus 로고
    • The effect of the nucleoside transport inhibitor dipyridamole on the incorporation of [3H]thymidine in the rat
    • Newell, D.R. et al. 1986. The effect of the nucleoside transport inhibitor dipyridamole on the incorporation of [3H]thymidine in the rat. Biochem. Pharmacol. 35: 3871- 3877.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 3871-3877
    • Newell, D.R.1
  • 59
    • 70449381345 scopus 로고    scopus 로고
    • Distribution of dipyridamole in blood components among post-stroke patients treated with extended release formulation
    • Serebruany, V. et al. 2009. Distribution of dipyridamole in blood components among post-stroke patients treated with extended release formulation. Thromb. Haemost. 102: 538- 543.
    • (2009) Thromb. Haemost. , vol.102 , pp. 538-543
    • Serebruany, V.1
  • 60
    • 0028258248 scopus 로고
    • Measurement of coronary blood flow velocity in conscious rats
    • Jones, L.F., S.K. Landas & A.K. Johnson. 1994.Measurement of coronary blood flow velocity in conscious rats. Am. J. Physiol. 266: H840-H845.
    • (1994) Am. J. Physiol.
    • Jones, L.F.1    Landas, S.K.2    Johnson, A.K.3
  • 61
    • 0035019827 scopus 로고    scopus 로고
    • Dipyridamole inhibits human peritoneal mesothelial cell proliferation in vitro and attenuates rat peritoneal fibrosis in vivo
    • Hung, K.Y. et al. 2001. Dipyridamole inhibits human peritoneal mesothelial cell proliferation in vitro and attenuates rat peritoneal fibrosis in vivo. Kidney Int. 59: 2316-2324.
    • (2001) Kidney Int , vol.59 , pp. 2316-2324
    • Hung, K.Y.1
  • 62
    • 2942731288 scopus 로고    scopus 로고
    • Chronic mild stress exacerbates the effects of permanent bilateral common carotid artery occlusion on CA1 neurons
    • Ritchie, L.J.,M. De Butte & B.A. Pappas. 2004. Chronic mild stress exacerbates the effects of permanent bilateral common carotid artery occlusion on CA1 neurons. Brain Res. 1014: 228-235.
    • (2004) Brain Res , vol.1014 , pp. 228-235
    • Ritchie, L.J.1    De Butte, M.2    Pappas, B.A.3
  • 63
    • 33846272150 scopus 로고    scopus 로고
    • Effect of the flavonoid, oroxylin A, on transient cerebral hypoperfusion-induced memory impairment in mice
    • Kim, D.H. et al. 2006. Effect of the flavonoid, oroxylin A, on transient cerebral hypoperfusion-induced memory impairment in mice. Pharmacol. Biochem. Behav. 85: 658-668.
    • (2006) Pharmacol. Biochem. Behav. , vol.85 , pp. 658-668
    • Kim, D.H.1
  • 64
    • 34548495793 scopus 로고    scopus 로고
    • Pre- treatment and post-treatment with alpha-tocopherol attenuates hippocampal neuronal damage in experimental cerebral hypoperfusion
    • Annaházi, A. et al. 2007. Pre-treatment and post-treatment with alpha-tocopherol attenuates hippocampal neuronal damage in experimental cerebral hypoperfusion. Eur. J. Pharmacol. 571: 120-128.
    • (2007) Eur. J. Pharmacol. , vol.571 , pp. 120-128
    • Annaházi, A.1
  • 65
    • 57349116897 scopus 로고    scopus 로고
    • Cell cycle proteins preceded neuronal death after chronic cerebral hypoperfusion in rats
    • Xu, L., Q. Di & Y. Zhang. 2008. Cell cycle proteins preceded neuronal death after chronic cerebral hypoperfusion in rats. Neurol. Res. 30: 932-939.
    • (2008) Neurol. Res. , vol.30 , pp. 932-939
    • Xu, L.1    Di, Q.2    Zhang, Y.3
  • 66
    • 0345307205 scopus 로고    scopus 로고
    • Chronic cerebral hypoperfusion induces white matter lesions and loss of oligodendroglia with DNA fragmentation in the rat
    • Tomimoto, H. et al. 2003. Chronic cerebral hypoperfusion induces white matter lesions and loss of oligodendroglia with DNA fragmentation in the rat. Acta Neuropathol. 106: 527-534
    • (2003) Acta Neuropathol , vol.106 , pp. 527-534
    • Tomimoto, H.1
  • 67
    • 64649102029 scopus 로고    scopus 로고
    • Doxycycline inhibits matrix metalloproteinase-9 and laminin degradation after transient global cerebral ischemia
    • Lee, H. et al. 2009. Doxycycline inhibits matrix metalloproteinase-9 and laminin degradation after transient global cerebral ischemia. Neurobiol. Dis. 34: 189-198.
    • (2009) Neurobiol. Dis. , vol.34 , pp. 189-198
    • Lee, H.1
  • 68
    • 0028988718 scopus 로고
    • A potential use of a 123I-labelled benzodiazepine receptor antagonist as a predictor of neuronal cell viability: comparisonswith 14C-labelled 2-deoxyglucose autoradiography and histopathological examination
    • Odano, I. et al. 1995. A potential use of a 123I-labelled benzodiazepine receptor antagonist as a predictor of neuronal cell viability: comparisonswith 14C-labelled 2-deoxyglucose autoradiography and histopathological examination. Nucl. Med. Commun. 16: 443-446.
    • (1995) Nucl. Med. Commun. , vol.16 , pp. 443-446
    • Odano, I.1
  • 69
    • 0028959038 scopus 로고
    • Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats
    • Garcia, J.H. et al. 1995. Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation. Stroke 26: 627-634.
    • (1995) Statistical validation. Stroke , vol.26 , pp. 627-634
    • Garcia, J.H.1
  • 70
    • 15244351970 scopus 로고    scopus 로고
    • The protective effect of adenosine A2A receptor antagonism in cerebral ischemia
    • Pedata, F. et al. 2005. The protective effect of adenosine A2A receptor antagonism in cerebral ischemia. Neurol. Res. 27: 169-174.
    • (2005) Neurol. Res. , vol.27 , pp. 169-174
    • Pedata, F.1
  • 71
    • 0030479855 scopus 로고    scopus 로고
    • Citicoline for treatment of experimental focal ischemia: histologic and behavioral outcome
    • Aronowski, J., R. Strong & J.C. Grotta. 1996. Citicoline for treatment of experimental focal ischemia: histologic and behavioral outcome. Neurol. Res. 18: 570-574.
    • (1996) Neurol. Res. , vol.18 , pp. 570-574
    • Aronowski, J.1    Strong, R.2    Grotta, J.C.3
  • 72
    • 0033526576 scopus 로고    scopus 로고
    • Interrelation between cerebral energy metabolism and behaviour in a rat model of permanent brain vessel occlusion
    • Plaschke, K. et al. 1999. Interrelation between cerebral energy metabolism and behaviour in a rat model of permanent brain vessel occlusion. Brain Res. 830: 320-329.
    • (1999) Brain Res , vol.830 , pp. 320-329
    • Plaschke, K.1
  • 73
    • 1542343843 scopus 로고    scopus 로고
    • Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity
    • Weinstock, M. & S. Shoham. 2004. Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity. J. Neural. Transm. 111: 347-366.
    • (2004) J. Neural. Transm. , vol.111 , pp. 347-366
    • Weinstock, M.1    Shoham, S.2
  • 74
    • 0036402443 scopus 로고    scopus 로고
    • Why do neuroprotective drugs that are so promising in animals fail in the clinic? An industry perspective
    • Green, A.R. 2002.Why do neuroprotective drugs that are so promising in animals fail in the clinic? An industry perspective. Clin. Exp. Pharmacol. Physiol. 29: 1030-1034.
    • (2002) Clin. Exp. Pharmacol. Physiol. , vol.29 , pp. 1030-1034
    • Green, A.R.1
  • 75
    • 0028887364 scopus 로고
    • YM796, a novel muscarinic agonist, improves the impairment of learning behavior in a rat model of chronic focal cerebral ischemia
    • Yamaguchi, T., M. Suzuki & M. Yamamoto. 1995. YM796, a novel muscarinic agonist, improves the impairment of learning behavior in a rat model of chronic focal cerebral ischemia. Brain Res. 669: 107-114.
    • (1995) Brain Res , vol.669 , pp. 107-114
    • Yamaguchi, T.1    Suzuki, M.2    Yamamoto, M.3
  • 76
    • 0029991601 scopus 로고    scopus 로고
    • Intracisternal basic fibroblast growth factor (bFGF) enhances behavioral recovery following focal cerebral infarction in the rat
    • Kawamata, T. et al. 1996. Intracisternal basic fibroblast growth factor (bFGF) enhances behavioral recovery following focal cerebral infarction in the rat. J. Cereb. Blood Flow Metab. 16: 542-547.
    • (1996) J. Cereb. Blood Flow Metab. , vol.16 , pp. 542-547
    • Kawamata, T.1
  • 77
    • 0035168782 scopus 로고    scopus 로고
    • A comparison of long-termfunctional outcome after 2 middle cerebral artery occlusion models in rats
    • Roof, R.L. et al. 2001. A comparison of long-termfunctional outcome after 2 middle cerebral artery occlusion models in rats. Stroke 32: 2648-2657.
    • (2001) Stroke , vol.32 , pp. 2648-2657
    • Roof, R.L.1
  • 78
    • 34249852075 scopus 로고    scopus 로고
    • Acute ischemic stroke: overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia
    • Durukan A. & T. Tatlisumak. 2007. Acute ischemic stroke: overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia. Pharmacol. Biochem. Behav. 87: 179-197.
    • (2007) Pharmacol. Biochem. Behav. , vol.87 , pp. 179-197
    • Durukan, A.1    Tatlisumak, T.2


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