Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation

Cell

Volumn 171, Issue 4, 2017, Pages 877-889.e17

  Yoon, Ki Jun ^a,b   Ringeling, Francisca Rojas ^b   Vissers, Caroline ^b   Jacob, Fadi ^b   Pokrass, Michael ^b   Jimenez Cyrus, Dennisse ^b   Su, Yijing ^a   Kim, Nam Shik ^a,b   Zhu, Yunhua ^b   Zheng, Lily ^b   Kim, Sunghan ^b   Wang, Xinyuan ^a   Doré, Louis C ^c   Jin, Peng ^d   Regot, Sergi ^b   Zhuang, Xiaoxi ^e   Canzar, Stefan ^f   He, Chuan ^c   Ming, Guo li ^a,b,g   Song, Hongjun ^a,b,g  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CHICAGO   (United States)

^f UNIVERSITY OF MUNICH   (Germany)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

autism; epitranscriptomics; human organoid; m6A; Mettl14; neurogenesis; radial glia cell; RNA methylation; schizophrenia; transcriptional prepatterning

Indexed keywords

6 N METHYLADENOSINE; EOMESODERMIN; MESSENGER RNA; METHYLTRANSFERASE; NESTIN; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX2; METTL14 PROTEIN, HUMAN; METTL14 PROTEIN, MOUSE; METTL3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; CELL CYCLE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EMBRYO; FETUS; GENE SILENCING; GLIA CELL; HUMAN; HUMAN TISSUE; MAMMAL; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN METHYLATION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE; TRANSCRIPTOMICS; ANIMAL; CYTOLOGY; EMBRYOLOGY; FOREBRAIN; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; METHYLATION; NERVOUS SYSTEM DEVELOPMENT; ORGANOID; RNA PROCESSING; RNA STABILITY;

ANIMALS; CELL CYCLE; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; HUMANS; METHYLATION; METHYLTRANSFERASES; MICE; MICE, KNOCKOUT; NEURAL STEM CELLS; NEUROGENESIS; ORGANOIDS; PROSENCEPHALON; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA STABILITY; RNA, MESSENGER;

EID: 85030682434     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.09.003     Document Type: Article

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