YTHDF2 destabilizes m 6 A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex

Nature Communications

Volumn 7, Issue , 2016, Pages

  Du, Hao ^a,b,c   Zhao, Ya ^a,b,c   He, Jinqiu ^d   Zhang, Yao ^e   Xi, Hairui ^a,b,c,f   Liu, Mofang ^c   Ma, Jinbiao ^d   Wu, Ligang ^a,b,c  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^d FUDAN UNIVERSITY   (China)

^e SHANGHAI INSTITUTE OF PLANNED PARENTHOOD RESEARCH   (China)

^f SHANGHAI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; CHEMOKINE RECEPTOR CCR4; CHROMATIN ASSEMBLY FACTOR 1; EXORIBONUCLEASE; LONG UNTRANSLATED RNA; PROTEIN; UNCLASSIFIED DRUG; YTHDF2 PROTEIN; CCR4 PROTEIN, HUMAN; CNOT1 PROTEIN, HUMAN; CNOT8 PROTEIN, HUMAN; MESSENGER RNA; MRNA DEADENYLASE; PROTEIN BINDING; RECOMBINANT PROTEIN; RIBONUCLEASE; RNA BINDING PROTEIN; TRANSCRIPTION FACTOR; YTHDF2 PROTEIN, HUMAN;

AMINO ACID; CELLS AND CELL COMPONENTS; DEGRADATION; ENZYME ACTIVITY; EUKARYOTE; GENE EXPRESSION; MAMMAL; METHYLATION; RNA;

ARTICLE; CONTROLLED STUDY; GENOMIC FRAGMENT; HEK293 CELL LINE; MAMMAL CELL; NONHUMAN; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; RNA DEGRADATION; RNA METHYLATION; SACCHAROMYCES CEREVISIAE; GENETICS; HELA CELL LINE; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; METHYLATION; POLYADENYLATION; PROTEIN DOMAIN; RNA STABILITY;

EUKARYOTA; MAMMALIA;

ADENOSINE; HEK293 CELLS; HELA CELLS; HUMANS; METHYLATION; POLYADENYLATION; PROTEIN BINDING; PROTEIN DOMAINS; RECEPTORS, CCR4; RECOMBINANT PROTEINS; RIBONUCLEASES; RNA STABILITY; RNA, MESSENGER; RNA-BINDING PROTEINS; TRANSCRIPTION FACTORS;

EID: 84983728274     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms12626     Document Type: Article

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