-
1
-
-
84874194072
-
DNA methylation: Roles in mammalian development
-
Smith, Z. D. & Meissner, A. DNA methylation: roles in mammalian development. Nature Rev. Genet. 14, 204-220 (2013).
-
(2013)
Nature Rev. Genet.
, vol.14
, pp. 204-220
-
-
Smith, Z.D.1
Meissner, A.2
-
2
-
-
84878260646
-
TETonic shift: Biological roles of TET proteins in DNA demethylation and transcription
-
Pastor, W. A., Aravind, L. & Rao, A. TETonic shift: biological roles of TET proteins in DNA demethylation and transcription. Nature Rev. Mol. Cell. Biol. 14, 341-356 (2013).
-
(2013)
Nature Rev. Mol. Cell. Biol.
, vol.14
, pp. 341-356
-
-
Pastor, W.A.1
Aravind, L.2
Rao, A.3
-
3
-
-
84878282462
-
Histone variants in pluripotency and disease
-
Skene, P. J. & Henikoff, S. Histone variants in pluripotency and disease. Development 140, 2513-2524 (2013).
-
(2013)
Development
, vol.140
, pp. 2513-2524
-
-
Skene, P.J.1
Henikoff, S.2
-
4
-
-
84872172975
-
Switching cell fate, ncRNAs coming to play
-
Guan, D., Zhang, W., Zhang, W., Liu, G. H. & Belmonte, J. C. Switching cell fate, ncRNAs coming to play. Cell Death Dis. 4, e464 (2013).
-
(2013)
Cell Death Dis.
, vol.4
-
-
Guan, D.1
Zhang, W.2
Zhang, W.3
Liu, G.H.4
Belmonte, J.C.5
-
5
-
-
84890559595
-
Long non-coding RNAs: New players in cell differentiation and development
-
Fatica, A. & Bozzoni, I. Long non-coding RNAs: new players in cell differentiation and development. Nature Rev. Genet. 15, 7-21 (2014).
-
(2014)
Nature Rev. Genet.
, vol.15
, pp. 7-21
-
-
Fatica, A.1
Bozzoni, I.2
-
6
-
-
75749101495
-
Chromatin remodelling during development
-
Ho, L. & Crabtree, G. R. Chromatin remodelling during development. Nature 463, 474-484 (2010).
-
(2010)
Nature
, vol.463
, pp. 474-484
-
-
Ho, L.1
Crabtree, G.R.2
-
7
-
-
8544279982
-
Ultrastructure of human embryonic stem cells and spontaneous and retinoic acid-induced differentiating cells
-
Park, S. H., Kook, M. C., Kim, E. Y., Park, S. & Lim, J. H. Ultrastructure of human embryonic stem cells and spontaneous and retinoic acid-induced differentiating cells. Ultrastruct. Pathol. 28, 229-238 (2004).
-
(2004)
Ultrastruct. Pathol.
, vol.28
, pp. 229-238
-
-
Park, S.H.1
Kook, M.C.2
Kim, E.Y.3
Park, S.4
Lim, J.H.5
-
8
-
-
29744447772
-
Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells
-
Meshorer, E. et al. Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. Dev. Cell 10, 105-116 (2006).
-
(2006)
Dev. Cell
, vol.10
, pp. 105-116
-
-
Meshorer, E.1
-
9
-
-
33646872978
-
Chromatin signatures of pluripotent cell lines
-
Azuara, V. et al. Chromatin signatures of pluripotent cell lines. Nature Cell Biol. 8, 532-538 (2006).
-
(2006)
Nature Cell Biol.
, vol.8
, pp. 532-538
-
-
Azuara, V.1
-
10
-
-
34447098370
-
A chromatin landmark and transcription initiation at most promoters in human cells
-
Guenther, M. G., Levine, S. S., Boyer, L. A., Jaenisch, R. & Young, R. A. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 130, 77-88 (2007).
-
(2007)
Cell
, vol.130
, pp. 77-88
-
-
Guenther, M.G.1
Levine, S.S.2
Boyer, L.A.3
Jaenisch, R.4
Young, R.A.5
-
11
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
Meissner, A. et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 454, 766-770 (2008).
-
(2008)
Nature
, vol.454
, pp. 766-770
-
-
Meissner, A.1
-
12
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister, R. et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 462, 315-322 (2009).
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
-
13
-
-
42649094468
-
Global transcription in pluripotent embryonic stem cells
-
Efroni, S. et al. Global transcription in pluripotent embryonic stem cells. Cell Stem Cell 2, 437-447 (2008).
-
(2008)
Cell Stem Cell
, vol.2
, pp. 437-447
-
-
Efroni, S.1
-
14
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein, B. E. et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125, 315-326 (2006)
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
-
15
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
Mikkelsen, T. S. et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448, 553-560 (2007).
-
(2007)
Nature
, vol.448
, pp. 553-560
-
-
Mikkelsen, T.S.1
-
16
-
-
34548424709
-
Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells
-
Zhao, X. D. et al. Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells. Cell Stem Cell 1, 286-298 (2007).
-
(2007)
Cell Stem Cell
, vol.1
, pp. 286-298
-
-
Zhao, X.D.1
-
17
-
-
34548434716
-
Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells
-
Pan, G. et al. Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells. Cell Stem Cell 1, 299-312 (2007).
-
(2007)
Cell Stem Cell
, vol.1
, pp. 299-312
-
-
Pan, G.1
-
18
-
-
84867009687
-
Asymmetrically modified nucleosomes
-
Voigt, P. et al. Asymmetrically modified nucleosomes. Cell 151, 181-193 (2012).
-
(2012)
Cell
, vol.151
, pp. 181-193
-
-
Voigt, P.1
-
19
-
-
77955759070
-
Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment
-
Alder, O. et al. Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment. Development 137, 2483-2492 (2010).
-
(2010)
Development
, vol.137
, pp. 2483-2492
-
-
Alder, O.1
-
20
-
-
77949407420
-
Histone H3 lysine 27 methylation asymmetry on developmentally-regulated promoters distinguish the first two lineages in mouse preimplantation embryos
-
Dahl, J. A., Reiner, A. H., Klungland, A., Wakayama, T. & Collas, P. Histone H3 lysine 27 methylation asymmetry on developmentally-regulated promoters distinguish the first two lineages in mouse preimplantation embryos. PLoS ONE 5, e9150 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Dahl, J.A.1
Reiner, A.H.2
Klungland, A.3
Wakayama, T.4
Collas, P.5
-
21
-
-
77954630809
-
Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo
-
Rugg-Gunn, P. J., Cox, B. J., Ralston, A. & Rossant, J. Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo. Proc. Natl Acad. Sci. USA 107, 10783-10790 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 10783-10790
-
-
Rugg-Gunn, P.J.1
Cox, B.J.2
Ralston, A.3
Rossant, J.4
-
22
-
-
58049191558
-
Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation
-
Cui, K. et al. Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation. Cell Stem Cell 4, 80-93 (2009).
-
(2009)
Cell Stem Cell
, vol.4
, pp. 80-93
-
-
Cui, K.1
-
23
-
-
77950866717
-
Chromatin signature of embryonic pluripotency is established during genome activation
-
Vastenhouw, N. L. et al. Chromatin signature of embryonic pluripotency is established during genome activation. Nature 464, 922-926 (2010).
-
(2010)
Nature
, vol.464
, pp. 922-926
-
-
Vastenhouw, N.L.1
-
24
-
-
69949156902
-
A hierarchy of H3K4me3 and H3K27me3 acquisition in spatial gene regulation in Xenopus embryos
-
Akkers, R. C. et al. A hierarchy of H3K4me3 and H3K27me3 acquisition in spatial gene regulation in Xenopus embryos. Dev. Cell 17, 425-434 (2009).
-
(2009)
Dev. Cell
, vol.17
, pp. 425-434
-
-
Akkers, R.C.1
-
25
-
-
58849088872
-
Functional anatomy of Polycomb and Trithorax chromatin landscapes in Drosophila embryos
-
Schuettengruber, B. et al. Functional anatomy of Polycomb and Trithorax chromatin landscapes in Drosophila embryos. PLoS Biol. 7, e13 (2009).
-
(2009)
PLoS Biol.
, vol.7
-
-
Schuettengruber, B.1
-
26
-
-
80052298366
-
Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage
-
Lien, W. H. et al. Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage. Cell Stem Cell 9, 219-232 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 219-232
-
-
Lien, W.H.1
-
27
-
-
33750488431
-
The genomic landscape of histone modifications in human T cells
-
Roh, T. Y., Cuddapah, S., Cui, K. & Zhao, K. The genomic landscape of histone modifications in human T cells. Proc. Natl Acad. Sci. USA 103, 15782-15787 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 15782-15787
-
-
Roh, T.Y.1
Cuddapah, S.2
Cui, K.3
Zhao, K.4
-
28
-
-
51649129596
-
Lineage-specific Polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors
-
Mohn, F. et al. Lineage-specific Polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol. Cell 30, 755-766 (2008).
-
(2008)
Mol. Cell
, vol.30
, pp. 755-766
-
-
Mohn, F.1
-
29
-
-
53049092465
-
Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states
-
Hayashi, K., Lopes, S. M., Tang, F. & Surani, M. A. Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states. Cell Stem Cell 3, 391-401 (2008).
-
(2008)
Cell Stem Cell
, vol.3
, pp. 391-401
-
-
Hayashi, K.1
Lopes, S.M.2
Tang, F.3
Surani, M.A.4
-
30
-
-
42149192008
-
Identification and characterization of subpopulations in undifferentiated ES cell culture
-
Toyooka, Y., Shimosato, D., Murakami, K., Takahashi, K. & Niwa, H. Identification and characterization of subpopulations in undifferentiated ES cell culture. Development 135, 909-918 (2008).
-
(2008)
Development
, vol.135
, pp. 909-918
-
-
Toyooka, Y.1
Shimosato, D.2
Murakami, K.3
Takahashi, K.4
Niwa, H.5
-
31
-
-
79960009805
-
Cell fate potential of human pluripotent stem cells is encoded by histone modifications
-
Hong, S. H. et al. Cell fate potential of human pluripotent stem cells is encoded by histone modifications. Cell Stem Cell 9, 24-36 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 24-36
-
-
Hong, S.H.1
-
32
-
-
66049117813
-
Naive and primed pluripotent states
-
Nichols, J. & Smith, A. Naive and primed pluripotent states. Cell Stem Cell 4, 487-492 (2009).
-
(2009)
Cell Stem Cell
, vol.4
, pp. 487-492
-
-
Nichols, J.1
Smith, A.2
-
33
-
-
84860351082
-
The transcriptional and epigenomic foundations of ground state pluripotency
-
Marks, H. et al. The transcriptional and epigenomic foundations of ground state pluripotency. Cell 149, 590-604 (2012).
-
(2012)
Cell
, vol.149
, pp. 590-604
-
-
Marks, H.1
-
34
-
-
59149083658
-
Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells
-
Wen, B., Wu, H., Shinkai, Y., Irizarry, R. A. & Feinberg, A. P. Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells. Nature Genet. 41, 246-250 (2009).
-
(2009)
Nature Genet.
, vol.41
, pp. 246-250
-
-
Wen, B.1
Wu, H.2
Shinkai, Y.3
Irizarry, R.A.4
Feinberg, A.P.5
-
35
-
-
59949085939
-
H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome
-
Pauler, F. M. et al. H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome. Genome Res. 19, 221-233 (2009).
-
(2009)
Genome Res.
, vol.19
, pp. 221-233
-
-
Pauler, F.M.1
-
36
-
-
84873310426
-
Genome-wide chromatin state transitions associated with developmental and environmental cues
-
Zhu, J. et al. Genome-wide chromatin state transitions associated with developmental and environmental cues. Cell 152, 642-654 (2013).
-
(2013)
Cell
, vol.152
, pp. 642-654
-
-
Zhu, J.1
-
37
-
-
79959853781
-
Genomic prevalence of heterochromatic H3K9me2 and transcription do not discriminate pluripotent from terminally differentiated cells
-
Lienert, F. et al. Genomic prevalence of heterochromatic H3K9me2 and transcription do not discriminate pluripotent from terminally differentiated cells. PLoS Genet. 7, e1002090 (2011).
-
(2011)
PLoS Genet.
, vol.7
-
-
Lienert, F.1
-
38
-
-
78650758676
-
Histone H3K27ac separates active from poised enhancers and predicts developmental state
-
Creyghton, M. P. et al. Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc. Natl Acad. Sci. USA 107, 21931-21936 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 21931-21936
-
-
Creyghton, M.P.1
-
39
-
-
79951516056
-
A unique chromatin signature uncovers early developmental enhancers in humans
-
Rada-Iglesias, A. et al. A unique chromatin signature uncovers early developmental enhancers in humans. Nature 470, 279-283 (2011).
-
(2011)
Nature
, vol.470
, pp. 279-283
-
-
Rada-Iglesias, A.1
-
40
-
-
84867073340
-
Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage
-
Wamstad, J. A. et al. Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage. Cell 151, 206-220 (2012).
-
(2012)
Cell
, vol.151
, pp. 206-220
-
-
Wamstad, J.A.1
-
41
-
-
84867095528
-
A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development
-
Paige, S. L. et al. A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development. Cell 151, 221-232 (2012).
-
(2012)
Cell
, vol.151
, pp. 221-232
-
-
Paige, S.L.1
-
42
-
-
84868484735
-
Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest
-
Rada-Iglesias, A. et al. Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest. Cell Stem Cell 11, 633-648 (2012).
-
(2012)
Cell Stem Cell
, vol.11
, pp. 633-648
-
-
Rada-Iglesias, A.1
-
43
-
-
84873702810
-
Dynamic chromatin remodeling mediated by Polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells
-
Xie, R. et al. Dynamic chromatin remodeling mediated by Polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells. Cell Stem Cell 12, 224-237 (2013).
-
(2013)
Cell Stem Cell
, vol.12
, pp. 224-237
-
-
Xie, R.1
-
44
-
-
84878292277
-
Transcriptional and epigenetic dynamics during specification of human embryonic stem cells
-
Gifford, C. A. et al. Transcriptional and epigenetic dynamics during specification of human embryonic stem cells. Cell 153, 1149-1163 (2013).
-
(2013)
Cell
, vol.153
, pp. 1149-1163
-
-
Gifford, C.A.1
-
45
-
-
84878282421
-
Epigenomic analysis of multilineage differentiation of human embryonic stem cells
-
Xie, W. et al. Epigenomic analysis of multilineage differentiation of human embryonic stem cells. Cell 153, 1134-1148 (2013).
-
(2013)
Cell
, vol.153
, pp. 1134-1148
-
-
Xie, W.1
-
46
-
-
77957220857
-
Comparative epigenomic analysis of murine and human adipogenesis
-
Mikkelsen, T. S. et al. Comparative epigenomic analysis of murine and human adipogenesis. Cell 143, 156-169 (2010).
-
(2010)
Cell
, vol.143
, pp. 156-169
-
-
Mikkelsen, T.S.1
-
47
-
-
77953521548
-
Promoter DNA methylation patterns of differentiated cells are largely programmed at the progenitor stage
-
Sorensen, A. L., Jacobsen, B. M., Reiner, A. H., Andersen, I. S. & Collas, P. Promoter DNA methylation patterns of differentiated cells are largely programmed at the progenitor stage. Mol. Biol. Cell 21, 2066-2077 (2010).
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 2066-2077
-
-
Sorensen, A.L.1
Jacobsen, B.M.2
Reiner, A.H.3
Andersen, I.S.4
Collas, P.5
-
48
-
-
84873732990
-
Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells
-
Herlofsen, S. R. et al. Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells. BMC Genomics 14, 105 (2013).
-
(2013)
BMC Genomics
, vol.14
, pp. 105
-
-
Herlofsen, S.R.1
-
49
-
-
84865369147
-
DNA methylation dynamics during in vivo differentiation of blood and skin stem cells
-
Bock, C. et al. DNA methylation dynamics during in vivo differentiation of blood and skin stem cells. Mol. Cell 47, 633-647 (2012).
-
(2012)
Mol. Cell
, vol.47
, pp. 633-647
-
-
Bock, C.1
-
50
-
-
0032582513
-
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
-
Nichols, J. et al. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95, 379-391 (1998).
-
(1998)
Cell
, vol.95
, pp. 379-391
-
-
Nichols, J.1
-
51
-
-
28344436489
-
Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation
-
Niwa, H. et al. Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation. Cell 123, 917-929 (2005).
-
(2005)
Cell
, vol.123
, pp. 917-929
-
-
Niwa, H.1
-
52
-
-
19744365010
-
Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst
-
Strumpf, D. et al. Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst. Development 132, 2093-2102 (2005).
-
(2005)
Development
, vol.132
, pp. 2093-2102
-
-
Strumpf, D.1
-
53
-
-
1542314243
-
Histone H3-K9 methyltransferase ESET is essential for early development
-
Dodge, J. E., Kang, Y. K., Beppu, H., Lei, H. & Li, E. Histone H3-K9 methyltransferase ESET is essential for early development. Mol. Cell. Biol. 24, 2478-2486 (2004).
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 2478-2486
-
-
Dodge, J.E.1
Kang, Y.K.2
Beppu, H.3
Lei, H.4
Li, E.5
-
54
-
-
70350686180
-
SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state
-
Bilodeau, S., Kagey, M. H., Frampton, G. M., Rahl, P. B. & Young, R. A. SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state. Genes Dev. 23, 2484-2489 (2009).
-
(2009)
Genes Dev.
, vol.23
, pp. 2484-2489
-
-
Bilodeau, S.1
Kagey, M.H.2
Frampton, G.M.3
Rahl, P.B.4
Young, R.A.5
-
55
-
-
70350686165
-
Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells
-
Yuan, P. et al. Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells. Genes Dev. 23, 2507-2520 (2009).
-
(2009)
Genes Dev.
, vol.23
, pp. 2507-2520
-
-
Yuan, P.1
-
56
-
-
77149144362
-
ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage
-
Yeap, L. S., Hayashi, K. & Surani, M. A. ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage. Epigenetics Chromatin 2, 12 (2009).
-
(2009)
Epigenetics Chromatin
, vol.2
, pp. 12
-
-
Yeap, L.S.1
Hayashi, K.2
Surani, M.A.3
-
57
-
-
77149138834
-
KMT1E mediated H3K9 methylation is required for the maintenance of embryonic stem cells by repressing trophectoderm differentiation
-
Lohmann, F. et al. KMT1E mediated H3K9 methylation is required for the maintenance of embryonic stem cells by repressing trophectoderm differentiation. Stem Cells 28, 201-212 (2010).
-
(2010)
Stem Cells
, vol.28
, pp. 201-212
-
-
Lohmann, F.1
-
58
-
-
34247333474
-
A component of the NuRD co-repressor complex, is required for development of pluripotent cells
-
Kaji, K., Nichols, J. & Hendrich, B. Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells. Development 134, 1123-1132 (2007).
-
(2007)
Development
, vol.134
, pp. 1123-1132
-
-
Kaji, K.1
Nichols, J.2
Mbd, H.B.3
-
59
-
-
33644764030
-
The NuRD component Mbd3 is required for pluripotency of embryonic stem cells
-
Kaji, K. et al. The NuRD component Mbd3 is required for pluripotency of embryonic stem cells. Nature Cell Biol. 8, 285-292 (2006).
-
(2006)
Nature Cell Biol.
, vol.8
, pp. 285-292
-
-
Kaji, K.1
-
60
-
-
70449552878
-
Mbd3, a component of NuRD/Mi-2 complex, helps maintain pluripotency of mouse embryonic stem cells by repressing trophectoderm differentiation
-
Zhu, D., Fang, J., Li, Y. & Zhang, J. Mbd3, a component of NuRD/Mi-2 complex, helps maintain pluripotency of mouse embryonic stem cells by repressing trophectoderm differentiation. PLoS ONE 4, e7684 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Zhu, D.1
Fang, J.2
Li, Y.3
Zhang, J.4
-
61
-
-
84964871806
-
NuRD-dependent DNA methylation prevents ES cells from accessing a trophectoderm fate
-
Latos, P. A. et al. NuRD-dependent DNA methylation prevents ES cells from accessing a trophectoderm fate. Biol. Open 1, 341-352 (2012).
-
(2012)
Biol. Open
, vol.1
, pp. 341-352
-
-
Latos, P.A.1
-
62
-
-
84860647928
-
NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment
-
Reynolds, N. et al. NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment. Cell Stem Cell 10, 583-594 (2012).
-
(2012)
Cell Stem Cell
, vol.10
, pp. 583-594
-
-
Reynolds, N.1
-
63
-
-
84856431427
-
NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb repressive complex 2 to direct gene repression
-
Reynolds, N. et al. NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb repressive complex 2 to direct gene repression. EMBO J. 31, 593-605 (2012).
-
(2012)
EMBO J.
, vol.31
, pp. 593-605
-
-
Reynolds, N.1
-
64
-
-
84455167621
-
Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells
-
Yildirim, O. et al. Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells. Cell 147, 1498-1510 (2011).
-
(2011)
Cell
, vol.147
, pp. 1498-1510
-
-
Yildirim, O.1
-
65
-
-
37549014206
-
The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis
-
Gupta, A. et al. The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis. Mol. Cell. Biol. 28, 397-409 (2008).
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 397-409
-
-
Gupta, A.1
-
66
-
-
49449109503
-
Mof (MYST1 or KAT8) is essential for progression of embryonic development past the blastocyst stage and required for normal chromatin architecture
-
Thomas, T., Dixon, M. P., Kueh, A. J. & Voss, A. K. Mof (MYST1 or KAT8) is essential for progression of embryonic development past the blastocyst stage and required for normal chromatin architecture. Mol. Cell. Biol. 28, 5093-5105 (2008).
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 5093-5105
-
-
Thomas, T.1
Dixon, M.P.2
Kueh, A.J.3
Voss, A.K.4
-
67
-
-
70350743144
-
Homozygous disruption of the Tip60 gene causes early embryonic lethality
-
Hu, Y. et al. Homozygous disruption of the Tip60 gene causes early embryonic lethality. Dev. Dyn. 238, 2912-2921 (2009).
-
(2009)
Dev. Dyn.
, vol.238
, pp. 2912-2921
-
-
Hu, Y.1
-
68
-
-
0034790436
-
Disruption of Trrap causes early embryonic lethality and defects in cell cycle progression
-
Herceg, Z. et al. Disruption of Trrap causes early embryonic lethality and defects in cell cycle progression. Nature Genet. 29, 206-211 (2001).
-
(2001)
Nature Genet.
, vol.29
, pp. 206-211
-
-
Herceg, Z.1
-
69
-
-
84864601941
-
The histone acetyltransferase MOF is a key regulator of the embryonic stem cell core transcriptional network
-
Li, X. et al. The histone acetyltransferase MOF is a key regulator of the embryonic stem cell core transcriptional network. Cell Stem Cell 11, 163-178 (2012).
-
(2012)
Cell Stem Cell
, vol.11
, pp. 163-178
-
-
Li, X.1
-
70
-
-
84876544529
-
Histone acetyltransferase cofactor Trrap maintains self-renewal and restricts differentiation of embryonic stem cells
-
Sawan, C. et al. Histone acetyltransferase cofactor Trrap maintains self-renewal and restricts differentiation of embryonic stem cells. Stem Cells 31, 979-991 (2013).
-
(2013)
Stem Cells
, vol.31
, pp. 979-991
-
-
Sawan, C.1
-
71
-
-
46149110511
-
An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity
-
Fazzio, T. G., Huff, J. T. & Panning, B. An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity. Cell 134, 162-174 (2008).
-
(2008)
Cell
, vol.134
, pp. 162-174
-
-
Fazzio, T.G.1
Huff, J.T.2
Panning, B.3
-
72
-
-
79954414897
-
Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network
-
Ang, Y. S. et al. Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell 145, 183-197 (2011).
-
(2011)
Cell
, vol.145
, pp. 183-197
-
-
Ang, Y.S.1
-
73
-
-
0031970236
-
Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein
-
LeGouy, E., Thompson, E. M., Muchardt, C. & Renard, J. P. Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein. Dev. Dyn. 212, 38-48 (1998).
-
(1998)
Dev. Dyn.
, vol.212
, pp. 38-48
-
-
Legouy, E.1
Thompson, E.M.2
Muchardt, C.3
Renard, J.P.4
-
74
-
-
33745619776
-
Maternal BRG1 regulates zygotic genome activation in the mouse
-
Bultman, S. J. et al. Maternal BRG1 regulates zygotic genome activation in the mouse. Genes Dev. 20, 1744-1754 (2006).
-
(2006)
Genes Dev.
, vol.20
, pp. 1744-1754
-
-
Bultman, S.J.1
-
75
-
-
0034502484
-
A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes
-
Bultman, S. et al. A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes. Mol. Cell 6, 1287-1295 (2000).
-
(2000)
Mol. Cell
, vol.6
, pp. 1287-1295
-
-
Bultman, S.1
-
76
-
-
0034572885
-
The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression
-
Klochendler-Yeivin, A. et al. The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression. EMBO Rep. 1, 500-506 (2000).
-
(2000)
EMBO Rep.
, vol.1
, pp. 500-506
-
-
Klochendler-Yeivin, A.1
-
77
-
-
0034769937
-
Srg3, a mouse homolog of yeast SWI3, is essential for early embryogenesis and involved in brain development
-
Kim, J. K. et al. Srg3, a mouse homolog of yeast SWI3, is essential for early embryogenesis and involved in brain development. Mol. Cell. Biol. 21, 7787-7795 (2001).
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 7787-7795
-
-
Kim, J.K.1
-
78
-
-
62549095522
-
SWI/SNF-Brg1 regulates self-renewal and occupies core pluripotency-related genes in embryonic stem cells
-
Kidder, B. L., Palmer, S. & Knott, J. G. SWI/SNF-Brg1 regulates self-renewal and occupies core pluripotency-related genes in embryonic stem cells. Stem Cells 27, 317-328 (2009).
-
(2009)
Stem Cells
, vol.27
, pp. 317-328
-
-
Kidder, B.L.1
Palmer, S.2
Knott, J.G.3
-
79
-
-
65249180173
-
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency
-
Ho, L. et al. An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency. Proc. Natl Acad. Sci. USA 106, 5181-5186 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 5181-5186
-
-
Ho, L.1
-
80
-
-
65249173999
-
An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network
-
Ho, L. et al. An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network. Proc. Natl Acad. Sci. USA 106, 5187-5191 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 5187-5191
-
-
Ho, L.1
-
81
-
-
79961002967
-
EsBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function
-
Ho, L. et al. esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function. Nature Cell Biol. 13, 903-913 (2011).
-
(2011)
Nature Cell Biol.
, vol.13
, pp. 903-913
-
-
Ho, L.1
-
82
-
-
0034977239
-
The Polycomb-group gene Ezh2 is required for early mouse development
-
O'Carroll, D. et al. The Polycomb-group gene Ezh2 is required for early mouse development. Mol. Cell. Biol. 21, 4330-4336 (2001).
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4330-4336
-
-
O'Carroll, D.1
-
83
-
-
0028910338
-
The eed mutation disrupts anterior mesoderm production in mice
-
Faust, C., Schumacher, A., Holdener, B. & Magnuson, T. The eed mutation disrupts anterior mesoderm production in mice. Development 121, 273-285 (1995).
-
(1995)
Development
, vol.121
, pp. 273-285
-
-
Faust, C.1
Schumacher, A.2
Holdener, B.3
Magnuson, T.4
-
84
-
-
8144230178
-
Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
-
Pasini, D., Bracken, A. P., Jensen, M. R., Lazzerini Denchi, E. & Helin, K. Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity. EMBO J. 23, 4061-4071 (2004).
-
(2004)
EMBO J.
, vol.23
, pp. 4061-4071
-
-
Pasini, D.1
Bracken, A.P.2
Jensen, M.R.3
Lazzerini Denchi, E.4
Helin, K.5
-
85
-
-
0345269795
-
Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition
-
Voncken, J. W. et al. Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition. Proc. Natl Acad. Sci. USA 100, 2468-2473 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 2468-2473
-
-
Voncken, J.W.1
-
86
-
-
23344450667
-
Rybp/DEDAF is required for early postimplantation and for central nervous system development
-
Pirity, M. K., Locker, J. & Schreiber-Agus, N. Rybp/DEDAF is required for early postimplantation and for central nervous system development. Mol. Cell. Biol. 25, 7193-7202 (2005).
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 7193-7202
-
-
Pirity, M.K.1
Locker, J.2
Schreiber-Agus, N.3
-
87
-
-
84866139087
-
The Polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development
-
Qin, J. et al. The Polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development. Cell Stem Cell 11, 319-332 (2012).
-
(2012)
Cell Stem Cell
, vol.11
, pp. 319-332
-
-
Qin, J.1
-
88
-
-
33646882068
-
Polycomb complexes repress developmental regulators in murine embryonic stem cells
-
Boyer, L. A. et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441, 349-353 (2006).
-
(2006)
Nature
, vol.441
, pp. 349-353
-
-
Boyer, L.A.1
-
89
-
-
34248169728
-
The Polycomb group protein Suz12 is required for embryonic stem cell differentiation
-
Pasini, D., Bracken, A. P., Hansen, J. B., Capillo, M. & Helin, K. The Polycomb group protein Suz12 is required for embryonic stem cell differentiation. Mol. Cell. Biol. 27, 3769-3779 (2007).
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 3769-3779
-
-
Pasini, D.1
Bracken, A.P.2
Hansen, J.B.3
Capillo, M.4
Helin, K.5
-
90
-
-
55949124844
-
EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency
-
Shen, X. et al. EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. Mol. Cell 32, 491-502 (2008).
-
(2008)
Mol. Cell
, vol.32
, pp. 491-502
-
-
Shen, X.1
-
91
-
-
76149142791
-
Polycomb complexes act redundantly to repress genomic repeats and genes
-
Leeb, M. et al. Polycomb complexes act redundantly to repress genomic repeats and genes. Genes Dev. 24, 265-276 (2010).
-
(2010)
Genes Dev.
, vol.24
, pp. 265-276
-
-
Leeb, M.1
-
92
-
-
84857845592
-
RYBP represses endogenous retroviruses and preimplantation-and germ line-specific genes in mouse embryonic stem cells
-
Hisada, K. et al. RYBP represses endogenous retroviruses and preimplantation-and germ line-specific genes in mouse embryonic stem cells. Mol. Cell. Biol. 32, 1139-1149 (2012).
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 1139-1149
-
-
Hisada, K.1
-
93
-
-
0037099413
-
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis
-
Tachibana, M. et al. G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev. 16, 1779-1791 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 1779-1791
-
-
Tachibana, M.1
-
94
-
-
84862565769
-
Protein kinase A determines timing of early differentiation through epigenetic regulation with G9a
-
Yamamizu, K. et al. Protein kinase A determines timing of early differentiation through epigenetic regulation with G9a. Cell Stem Cell 10, 759-770 (2012).
-
(2012)
Cell Stem Cell
, vol.10
, pp. 759-770
-
-
Yamamizu, K.1
-
95
-
-
33645132331
-
G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis
-
Feldman, N. et al. G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis. Nature Cell Biol. 8, 188-194 (2006).
-
(2006)
Nature Cell Biol.
, vol.8
, pp. 188-194
-
-
Feldman, N.1
-
96
-
-
55549145072
-
De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes
-
Epsztejn-Litman, S. et al. De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes. Nature Struct. Mol. Biol. 15, 1176-1183 (2008).
-
(2008)
Nature Struct. Mol. Biol.
, vol.15
, pp. 1176-1183
-
-
Epsztejn-Litman, S.1
-
97
-
-
54349095323
-
G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription
-
Tachibana, M., Matsumura, Y., Fukuda, M., Kimura, H. & Shinkai, Y. G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription. EMBO J. 27, 2681-2690 (2008).
-
(2008)
EMBO J.
, vol.27
, pp. 2681-2690
-
-
Tachibana, M.1
Matsumura, Y.2
Fukuda, M.3
Kimura, H.4
Shinkai, Y.5
-
98
-
-
54349114603
-
DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity
-
Dong, K. B. et al. DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity. EMBO J. 27, 2691-2701 (2008).
-
(2008)
EMBO J.
, vol.27
, pp. 2691-2701
-
-
Dong, K.B.1
-
99
-
-
37549015214
-
Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog
-
Li, J. Y. et al. Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog. Mol. Cell. Biol. 27, 8748-8759 (2007).
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 8748-8759
-
-
Li, J.Y.1
-
100
-
-
0033623238
-
Loss of Gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development
-
Xu, W. et al. Loss of Gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development. Nature Genet. 26, 229-232 (2000).
-
(2000)
Nature Genet.
, vol.26
, pp. 229-232
-
-
Xu, W.1
-
101
-
-
0034633644
-
Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis
-
Yamauchi, T. et al. Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis. Proc. Natl Acad. Sci. USA 97, 11303-11306 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 11303-11306
-
-
Yamauchi, T.1
-
102
-
-
34250676810
-
-/-embryonic stem cells in vivo and in vitro
-
-/-embryonic stem cells in vivo and in vitro. Dev. Dyn. 236, 1547-1557 (2007).
-
(2007)
Dev. Dyn.
, vol.236
, pp. 1547-1557
-
-
Lin, W.1
-
103
-
-
34247646897
-
Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos
-
Bu, P., Evrard, Y. A., Lozano, G. & Dent, S. Y. Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos. Mol. Cell. Biol. 27, 3405-3416 (2007).
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 3405-3416
-
-
Bu, P.1
Evrard, Y.A.2
Lozano, G.3
Dent, S.Y.4
-
104
-
-
68349133311
-
Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance
-
Atanassov, B. S. et al. Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance. Mol. Cell 35, 352-364 (2009).
-
(2009)
Mol. Cell
, vol.35
, pp. 352-364
-
-
Atanassov, B.S.1
-
105
-
-
80052281618
-
USP22 regulates cell proliferation by deubiquitinating the transcriptional regulator FBP1
-
Atanassov, B. S. & Dent, S. Y. USP22 regulates cell proliferation by deubiquitinating the transcriptional regulator FBP1. EMBO Rep. 12, 924-930 (2011).
-
(2011)
EMBO Rep.
, vol.12
, pp. 924-930
-
-
Atanassov, B.S.1
Dent, S.Y.2
-
106
-
-
84861968321
-
RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation
-
Fuchs, G. et al. RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation. Mol. Cell 46, 662-673 (2012).
-
(2012)
Mol. Cell
, vol.46
, pp. 662-673
-
-
Fuchs, G.1
-
107
-
-
84861994785
-
The histone H2B monoubiquitination regulatory pathway is required for differentiation of multipotent stem cells
-
Karpiuk, O. et al. The histone H2B monoubiquitination regulatory pathway is required for differentiation of multipotent stem cells. Mol. Cell 46, 705-713 (2012).
-
(2012)
Mol. Cell
, vol.46
, pp. 705-713
-
-
Karpiuk, O.1
-
108
-
-
84865765333
-
Histone H2B lysine 120 monoubiquitination is required for embryonic stem cell differentiation
-
Chen, S., Li, J., Wang, D. L. & Sun, F. L. Histone H2B lysine 120 monoubiquitination is required for embryonic stem cell differentiation. Cell Res. 22, 1402-1405 (2012).
-
(2012)
Cell Res.
, vol.22
, pp. 1402-1405
-
-
Chen, S.1
Li, J.2
Wang, D.L.3
Sun, F.L.4
-
109
-
-
84859259227
-
Histone ubiquitylation and chromatin dynamics
-
Wright, D. E., Wang, C. Y. & Kao, C. F. Histone ubiquitylation and chromatin dynamics. Front. Biosci. 17, 1051-1078 (2012).
-
(2012)
Front. Biosci.
, vol.17
, pp. 1051-1078
-
-
Wright, D.E.1
Wang, C.Y.2
Kao, C.F.3
-
110
-
-
84877001348
-
Brg1 governs a positive feedback circuit in the hair follicle for tissue regeneration and repair
-
Xiong, Y. et al. Brg1 governs a positive feedback circuit in the hair follicle for tissue regeneration and repair. Dev. Cell 25, 169-181 (2013).
-
(2013)
Dev. Cell
, vol.25
, pp. 169-181
-
-
Xiong, Y.1
-
111
-
-
84864841050
-
Dnmt3a regulates both proliferation and differentiation of mouse neural stem cells
-
Wu, Z. et al. Dnmt3a regulates both proliferation and differentiation of mouse neural stem cells. J. Neurosci. Res. 90, 1883-1891 (2012).
-
(2012)
J. Neurosci. Res.
, vol.90
, pp. 1883-1891
-
-
Wu, Z.1
-
112
-
-
84881178902
-
Tet1 regulates adult hippocampal neurogenesis and cognition
-
Zhang, R. R. et al. Tet1 regulates adult hippocampal neurogenesis and cognition. Cell Stem Cell 13, 237-245 (2013).
-
(2013)
Cell Stem Cell
, vol.13
, pp. 237-245
-
-
Zhang, R.R.1
-
113
-
-
79961139741
-
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development
-
Dawlaty, M. M. et al. Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development. Cell Stem Cell 9, 166-175 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 166-175
-
-
Dawlaty, M.M.1
-
114
-
-
14044259362
-
Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage
-
Szutorisz, H. et al. Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage. Mol. Cell. Biol. 25, 1804-1820 (2005).
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 1804-1820
-
-
Szutorisz, H.1
-
115
-
-
79956326274
-
Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas
-
Xu, C. R. et al. Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas. Science 332, 963-966 (2011).
-
(2011)
Science
, vol.332
, pp. 963-966
-
-
Xu, C.R.1
-
116
-
-
84887852466
-
Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming
-
Apostolou, E. et al. Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming. Cell Stem Cell 12, 699-712 (2013).
-
(2013)
Cell Stem Cell
, vol.12
, pp. 699-712
-
-
Apostolou, E.1
-
117
-
-
84887835943
-
Klf4 organizes long-range chromosomal interactions with the Oct4 locus in reprogramming and pluripotency
-
Wei, Z. et al. Klf4 organizes long-range chromosomal interactions with the Oct4 locus in reprogramming and pluripotency. Cell Stem Cell 13, 36-47 (2013).
-
(2013)
Cell Stem Cell
, vol.13
, pp. 36-47
-
-
Wei, Z.1
-
118
-
-
80455144479
-
Pioneer transcription factors: Establishing competence for gene expression
-
Zaret, K. S. & Carroll, J. S. Pioneer transcription factors: establishing competence for gene expression. Genes Dev. 25, 2227-2241 (2011).
-
(2011)
Genes Dev.
, vol.25
, pp. 2227-2241
-
-
Zaret, K.S.1
Carroll, J.S.2
-
119
-
-
84857367297
-
RYBP-PRC1 complexes mediate H2A ubiquitylation at Polycomb target sites independently of PRC2 and H3K27me3
-
Tavares, L. et al. RYBP-PRC1 complexes mediate H2A ubiquitylation at Polycomb target sites independently of PRC2 and H3K27me3. Cell 148, 664-678 (2012).
-
(2012)
Cell
, vol.148
, pp. 664-678
-
-
Tavares, L.1
-
120
-
-
84863011309
-
PCGF homologs CBX proteins and RYBP define functionally distinct PRC1 family complexes
-
Gao, Z. et al. PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes. Mol. Cell 45, 344-356 (2012).
-
(2012)
Mol. Cell
, vol.45
, pp. 344-356
-
-
Gao, Z.1
-
121
-
-
84875799835
-
Fbxl10/Kdm2b recruits Polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation
-
Wu, X., Johansen, J. V. & Helin, K. Fbxl10/Kdm2b recruits Polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation. Mol. Cell 49, 1134-1146 (2013).
-
(2013)
Mol. Cell
, vol.49
, pp. 1134-1146
-
-
Wu, X.1
Johansen, J.V.2
Helin, K.3
-
122
-
-
84876497474
-
Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes
-
He, J. et al. Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes. Nature Cell Biol. 15, 373-384 (2013).
-
(2013)
Nature Cell Biol.
, vol.15
, pp. 373-384
-
-
He, J.1
-
123
-
-
84862908896
-
MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation
-
O'Loghlen, A. et al. MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation. Cell Stem Cell 10, 33-46 (2012).
-
(2012)
Cell Stem Cell
, vol.10
, pp. 33-46
-
-
O'Loghlen, A.1
-
124
-
-
84855516244
-
Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells
-
Morey, L. et al. Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells. Cell Stem Cell 10, 47-62 (2012).
-
(2012)
Cell Stem Cell
, vol.10
, pp. 47-62
-
-
Morey, L.1
-
125
-
-
69449102464
-
Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes
-
Wang, Z. et al. Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes. Cell 138, 1019-1031 (2009).
-
(2009)
Cell
, vol.138
, pp. 1019-1031
-
-
Wang, Z.1
-
126
-
-
34249099730
-
Combined action of PHD and chromo domains directs the Rpd3S HDAC to transcribed chromatin
-
Li, B. et al. Combined action of PHD and chromo domains directs the Rpd3S HDAC to transcribed chromatin. Science 316, 1050-1054 (2007).
-
(2007)
Science
, vol.316
, pp. 1050-1054
-
-
Li, B.1
-
127
-
-
84875125402
-
Epigenetics of reprogramming to induced pluripotency
-
Papp, B. & Plath, K. Epigenetics of reprogramming to induced pluripotency. Cell 152, 1324-1343 (2013).
-
(2013)
Cell
, vol.152
, pp. 1324-1343
-
-
Papp, B.1
Plath, K.2
-
128
-
-
46449094276
-
Dissecting direct reprogramming through integrative genomic analysis
-
Mikkelsen, T. S. et al. Dissecting direct reprogramming through integrative genomic analysis. Nature 454, 49-55 (2008).
-
(2008)
Nature
, vol.454
, pp. 49-55
-
-
Mikkelsen, T.S.1
-
129
-
-
77953727663
-
Chromatin-remodeling components of the BAF complex facilitate reprogramming
-
Singhal, N. et al. Chromatin-remodeling components of the BAF complex facilitate reprogramming. Cell 141, 943-955 (2010).
-
(2010)
Cell
, vol.141
, pp. 943-955
-
-
Singhal, N.1
-
130
-
-
84859218238
-
Chromatin-modifying enzymes as modulators of reprogramming
-
Onder, T. T. et al. Chromatin-modifying enzymes as modulators of reprogramming. Nature 483, 598-602 (2012).
-
(2012)
Nature
, vol.483
, pp. 598-602
-
-
Onder, T.T.1
-
131
-
-
84870058502
-
Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome
-
Soufi, A., Donahue, G. & Zaret, K. S. Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome. Cell 151, 994-1004 (2012).
-
(2012)
Cell
, vol.151
, pp. 994-1004
-
-
Soufi, A.1
Donahue, G.2
Zaret, K.S.3
-
132
-
-
84871990064
-
H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs
-
Chen, J. et al. H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nature Genet. 45, 34-42 (2013).
-
(2013)
Nature Genet.
, vol.45
, pp. 34-42
-
-
Chen, J.1
-
133
-
-
84885619736
-
Deterministic direct reprogramming of somatic cells to pluripotency
-
Rais, Y. et al. Deterministic direct reprogramming of somatic cells to pluripotency. Nature 502, 65-70 (2013).
-
(2013)
Nature
, vol.502
, pp. 65-70
-
-
Rais, Y.1
-
134
-
-
58149522909
-
Making copies of chromatin: The challenge of nucleosomal organization and epigenetic information
-
Corpet, A. & Almouzni, G. Making copies of chromatin: the challenge of nucleosomal organization and epigenetic information. Trends Cell Biol. 19, 29-41 (2009).
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 29-41
-
-
Corpet, A.1
Almouzni, G.2
-
135
-
-
84865681429
-
TrxG and PcG proteins but not methylated histones remain associated with DNA through replication
-
Petruk, S. et al. TrxG and PcG proteins but not methylated histones remain associated with DNA through replication. Cell 150, 922-933 (2012).
-
(2012)
Cell
, vol.150
, pp. 922-933
-
-
Petruk, S.1
-
136
-
-
63049138876
-
Polycomb proteins remain bound to chromatin and DNA during DNA replication in vitro
-
Francis, N. J., Follmer, N. E., Simon, M. D., Aghia, G. & Butler, J. D. Polycomb proteins remain bound to chromatin and DNA during DNA replication in vitro. Cell 137, 110-122 (2009).
-
(2009)
Cell
, vol.137
, pp. 110-122
-
-
Francis, N.J.1
Follmer, N.E.2
Simon, M.D.3
Aghia, G.4
Butler, J.D.5
-
137
-
-
80052942443
-
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
-
Tan, M. et al. Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell 146, 1016-1028 (2011).
-
(2011)
Cell
, vol.146
, pp. 1016-1028
-
-
Tan, M.1
-
138
-
-
34447528757
-
New cell lines from mouse epiblast share defining features with human embryonic stem cells
-
Tesar, P. J. et al. New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 448, 196-199 (2007).
-
(2007)
Nature
, vol.448
, pp. 196-199
-
-
Tesar, P.J.1
-
139
-
-
84874116331
-
Chromatin: Receiver and quarterback for cellular signals
-
Johnson, D. G. & Dent, S. Y. Chromatin: receiver and quarterback for cellular signals. Cell 152, 685-689 (2013).
-
(2013)
Cell
, vol.152
, pp. 685-689
-
-
Johnson, D.G.1
Dent, S.Y.2
-
140
-
-
84863621527
-
Cancer epigenetics: From mechanism to therapy
-
Dawson, M. A. & Kouzarides, T. Cancer epigenetics: from mechanism to therapy. Cell 150, 12-27 (2012).
-
(2012)
Cell
, vol.150
, pp. 12-27
-
-
Dawson, M.A.1
Kouzarides, T.2
-
141
-
-
79955972412
-
L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure
-
Trojer, P. et al. L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure. Mol. Cell 42, 438-450 (2011).
-
(2011)
Mol. Cell
, vol.42
, pp. 438-450
-
-
Trojer, P.1
|