The chromatin accessibility signature of human immune aging stems from CD8+ T cells

Journal of Experimental Medicine

Volumn 214, Issue 10, 2017, Pages 3123-3144

  Ucar, Duygu ^a,d   Márquez, Eladio J ^a   Chung, Cheng Han ^a,b   Marches, Radu ^a   Rossi, Robert J ^a   Uyar, Asli ^a   Wu, Te Chia ^a   George, Joshy ^a   Stitzel, Michael L ^a,d   Karolina Palucka, A ^a   Kuchel, George A ^c   Banchereau, Jacques ^a  

^a JACKSON LABORATORY   (United States)

^b BAYLOR UNIVERSITY   (United States)

^c UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^d UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 7; STAT PROTEIN; TRANSCRIPTOME; BIOLOGICAL MARKER; CHROMATIN; IL7 PROTEIN, HUMAN; IL7R PROTEIN, HUMAN; INTERLEUKIN 7 RECEPTOR ALPHA;

AGED; ARTICLE; CD8+ T LYMPHOCYTE; CELL AGING; CHROMATIN; CONTROLLED STUDY; ENHANCER REGION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOLOGY; INTRACELLULAR SIGNALING; MONOCYTE; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; T LYMPHOCYTE; ADULT; AGING; FEMALE; GENETIC EPIGENESIS; MALE; MONONUCLEAR CELL; PHYSIOLOGY; SIGNAL TRANSDUCTION; YOUNG ADULT;

ADULT; AGED; AGING; BIOMARKERS; CD8-POSITIVE T-LYMPHOCYTES; CHROMATIN; EPIGENESIS, GENETIC; FEMALE; HUMANS; INTERLEUKIN-7; INTERLEUKIN-7 RECEPTOR ALPHA SUBUNIT; LEUKOCYTES, MONONUCLEAR; MALE; SIGNAL TRANSDUCTION; YOUNG ADULT;

EID: 85030632976     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20170416     Document Type: Article

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