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Volumn 6, Issue , 2015, Pages

Widespread seasonal gene expression reveals annual differences in human immunity and physiology

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 6 RECEPTOR; MESSENGER RNA; ARNTL PROTEIN, HUMAN; TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTOME;

EID: 84964294900     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8000     Document Type: Article
Times cited : (358)

References (70)
  • 1
    • 84863980440 scopus 로고    scopus 로고
    • Seasonal bone growth and physiology in endotherms shed light on dinosaur physiology
    • Kohler, M., Marin-Moratalla, N., Jordana, X. & Aanes, R. Seasonal bone growth and physiology in endotherms shed light on dinosaur physiology. Nature 487, 358-361 (2012).
    • (2012) Nature , vol.487 , pp. 358-361
    • Kohler, M.1    Marin-Moratalla, N.2    Jordana, X.3    Aanes, R.4
  • 2
    • 0037136548 scopus 로고    scopus 로고
    • Molecular basis of seasonal time measurement in Arabidopsis
    • Yanovsky, M. J. & Kay, S. A. Molecular basis of seasonal time measurement in Arabidopsis. Nature 419, 308-312 (2002).
    • (2002) Nature , vol.419 , pp. 308-312
    • Yanovsky, M.J.1    Kay, S.A.2
  • 3
    • 84901919930 scopus 로고    scopus 로고
    • On the value of seasonal mammals for identifying mechanisms underlying the control of food intake and body weight
    • Ebling, F. J. On the value of seasonal mammals for identifying mechanisms underlying the control of food intake and body weight. Horm. Behav. 66, 56-65 (2014).
    • (2014) Horm. Behav , vol.66 , pp. 56-65
    • Ebling, F.J.1
  • 4
    • 84993907194 scopus 로고
    • Seasonal conditions determine the manner of skin rejection in reptiles
    • Afifi, A., Mohamed, E. R. & Ridi, R. E. Seasonal conditions determine the manner of skin rejection in reptiles. J. Exp. Zool. 265, 459-468 (1993).
    • (1993) J. Exp. Zool , vol.265 , pp. 459-468
    • Afifi, A.1    Mohamed, E.R.2    Ridi, R.E.3
  • 5
    • 0017886310 scopus 로고
    • Seasonal variations in gonadal hormones and social behavior in squirrel monkeys
    • Mendoza, S. P., Lowe, E. L., Resko, J. A. & Levine, S. Seasonal variations in gonadal hormones and social behavior in squirrel monkeys. Physiol. Behav. 20, 515-522 (1978).
    • (1978) Physiol. Behav , vol.20 , pp. 515-522
    • Mendoza, S.P.1    Lowe, E.L.2    Resko, J.A.3    Levine, S.4
  • 6
    • 0032718409 scopus 로고    scopus 로고
    • Seasonal variations in coronary heart disease
    • Pell, J. P. & Cobbe, S. M. Seasonal variations in coronary heart disease. QJM 92, 689-696 (1999).
    • (1999) QJM , vol.92 , pp. 689-696
    • Pell, J.P.1    Cobbe, S.M.2
  • 7
    • 0032727580 scopus 로고    scopus 로고
    • Seasonal variations in out of hospital cardiopulmonary arrest
    • Pell, J. P., Sirel, J., Marsden, A. K. & Cobbe, S. M. Seasonal variations in out of hospital cardiopulmonary arrest. Heart 82, 680-683 (1999).
    • (1999) Heart , vol.82 , pp. 680-683
    • Pell, J.P.1    Sirel, J.2    Marsden, A.K.3    Cobbe, S.M.4
  • 8
    • 34347270615 scopus 로고    scopus 로고
    • What's in season for rheumatoid arthritis patients? Seasonal fluctuations in disease activity
    • Iikuni, N. et al. What's in season for rheumatoid arthritis patients? Seasonal fluctuations in disease activity. Rheumatology 46, 846-848 (2007).
    • (2007) Rheumatology , vol.46 , pp. 846-848
    • Iikuni, N.1
  • 9
    • 67649756856 scopus 로고    scopus 로고
    • Seasonal variation of diagnosis of Type 1 diabetes mellitus in children worldwide
    • Moltchanova, E. V., Schreier, N., Lammi, N. & Karvonen, M. Seasonal variation of diagnosis of Type 1 diabetes mellitus in children worldwide. Diabet. Med. 26, 673-678 (2009).
    • (2009) Diabet. Med , vol.26 , pp. 673-678
    • Moltchanova, E.V.1    Schreier, N.2    Lammi, N.3    Karvonen, M.4
  • 10
    • 0021346858 scopus 로고
    • Seasonal affective disorder. A description of the syndrome and preliminary findings with light therapy
    • Rosenthal, N. E. et al. Seasonal affective disorder. A description of the syndrome and preliminary findings with light therapy. Arch. Gen. Psychiatry 41, 72-80 (1984).
    • (1984) Arch. Gen. Psychiatry , vol.41 , pp. 72-80
    • Rosenthal, N.E.1
  • 11
    • 0037237575 scopus 로고    scopus 로고
    • Seasonality of symptom onset in first-episode schizophrenia
    • Owens, N. & McGorry, P. D. Seasonality of symptom onset in first-episode schizophrenia. Psychol. Med. 33, 163-167 (2003).
    • (2003) Psychol. Med , vol.33 , pp. 163-167
    • Owens, N.1    McGorry, P.D.2
  • 12
    • 0021366176 scopus 로고
    • Schizophrenic birth seasonality in relation to the incidence of infectious diseases and temperature extremes
    • Watson, C. G., Kucala, T., Tilleskjor, C. & Jacobs, L. Schizophrenic birth seasonality in relation to the incidence of infectious diseases and temperature extremes. Arch. Gen. Psychiatry 41, 85-90 (1984).
    • (1984) Arch. Gen. Psychiatry , vol.41 , pp. 85-90
    • Watson, C.G.1    Kucala, T.2    Tilleskjor, C.3    Jacobs, L.4
  • 13
    • 34249742034 scopus 로고    scopus 로고
    • Seasonality of infectious diseases
    • Fisman, D. N. Seasonality of infectious diseases. Annu. Rev. Public Health 28, 127-143 (2007).
    • (2007) Annu. Rev. Public Health , vol.28 , pp. 127-143
    • Fisman, D.N.1
  • 14
    • 0035348082 scopus 로고    scopus 로고
    • Seasonal variation in host susceptibility and cycles of certain infectious diseases
    • Dowell, S. F. Seasonal variation in host susceptibility and cycles of certain infectious diseases. Emerg. Infect. Dis. 7, 369-374 (2001).
    • (2001) Emerg. Infect. Dis , vol.7 , pp. 369-374
    • Dowell, S.F.1
  • 15
    • 84879255715 scopus 로고    scopus 로고
    • Serum seasonality in the United States
    • Kasahara, A. K., Singh, R. J. & Noymer, A. Vitamin D (25OHD) serum seasonality in the United States. PloS ONE 8, e65785 (2013).
    • (2013) PloS ONE , vol.8
    • Kasahara, A.K.1    Singh, R.J.2
  • 16
    • 0034704203 scopus 로고    scopus 로고
    • Mop3 is an essential component of the master circadian pacemaker in mammals
    • Bunger, M. K. et al. Mop3 is an essential component of the master circadian pacemaker in mammals. Cell 103, 1009-1017 (2000).
    • (2000) Cell , vol.103 , pp. 1009-1017
    • Bunger, M.K.1
  • 17
    • 33746191906 scopus 로고    scopus 로고
    • Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock
    • Kondratov, R. V., Kondratova, A. A., Gorbacheva, V. Y., Vykhovanets, O. V. & Antoch, M. P. Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock. Genes Dev. 20, 1868-1873 (2006).
    • (2006) Genes Dev , vol.20 , pp. 1868-1873
    • Kondratov, R.V.1    Kondratova, A.A.2    Gorbacheva, V.Y.3    Vykhovanets, O.V.4    Antoch, M.P.5
  • 18
    • 0034671791 scopus 로고    scopus 로고
    • Orchestrated transcription of key pathways in Arabidopsis by the circadian clock
    • Harmer, S. L. et al. Orchestrated transcription of key pathways in Arabidopsis by the circadian clock. Science 290, 2110-2113 (2000).
    • (2000) Science , vol.290 , pp. 2110-2113
    • Harmer, S.L.1
  • 19
    • 78650030217 scopus 로고    scopus 로고
    • Daily and seasonal adaptation of the circadian clock requires plasticity of the SCN neuronal network
    • Meijer, J. H., Michel, S., Vanderleest, H. T. & Rohling, J. H. Daily and seasonal adaptation of the circadian clock requires plasticity of the SCN neuronal network. Eur. J. Neurosci. 32, 2143-2151 (2010).
    • (2010) Eur. J. Neurosci , vol.32 , pp. 2143-2151
    • Meijer, J.H.1    Michel, S.2    Vanderleest, H.T.3    Rohling, J.H.4
  • 20
    • 77951889295 scopus 로고    scopus 로고
    • The mammalian circadian timing system: Organization and coordination of central and peripheral clocks
    • Dibner, C., Schibler, U. & Albrecht, U. The mammalian circadian timing system: organization and coordination of central and peripheral clocks. Annu. Rev. Physiol. 72, 517-549 (2010).
    • (2010) Annu. Rev. Physiol , vol.72 , pp. 517-549
    • Dibner, C.1    Schibler, U.2    Albrecht, U.3
  • 21
    • 84896727522 scopus 로고    scopus 로고
    • Circadian behavior is light-reprogrammed by plastic DNA methylation
    • Azzi, A. et al. Circadian behavior is light-reprogrammed by plastic DNA methylation. Nat. Neurosci. 17, 377-382 (2014).
    • (2014) Nat. Neurosci , vol.17 , pp. 377-382
    • Azzi, A.1
  • 22
    • 84895128336 scopus 로고    scopus 로고
    • Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock
    • Dyar, K. A. et al. Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock. Mol. Metabol. 3, 29-41 (2014).
    • (2014) Mol. Metabol , vol.3 , pp. 29-41
    • Dyar, K.A.1
  • 23
    • 84909592563 scopus 로고    scopus 로고
    • A circadian gene expression atlas in mammals: Implications for biology and medicine
    • Zhang, R., Lahens, N. F., Ballance, H. I., Hughes, M. E. & Hogenesch, J. B. A circadian gene expression atlas in mammals: Implications for biology and medicine. Proc. Natl Acad. Sci.USA 111, 16219-16224 (2014).
    • (2014) Proc. Natl Acad. Sci.USA , vol.111 , pp. 16219-16224
    • Zhang, R.1    Lahens, N.F.2    Ballance, H.I.3    Hughes, M.E.4    Hogenesch, J.B.5
  • 24
    • 0015861965 scopus 로고
    • Periodicity of susceptibility to pneumococcal infection: Influence of light and adrenocortical secretions
    • Shackelford, P. G. & Feigin, R. D. Periodicity of susceptibility to pneumococcal infection: influence of light and adrenocortical secretions. Science 182, 285-287 (1973).
    • (1973) Science , vol.182 , pp. 285-287
    • Shackelford, P.G.1    Feigin, R.D.2
  • 26
    • 84857388082 scopus 로고    scopus 로고
    • The circadian clock controls toll-like receptor 9-mediated innate and adaptive immunity
    • Silver, A. C., Arjona, A., Walker, W. E. & Fikrig, E. The circadian clock controls toll-like receptor 9-mediated innate and adaptive immunity. Immunity 36, 251-261 (2012).
    • (2012) Immunity , vol.36 , pp. 251-261
    • Silver, A.C.1    Arjona, A.2    Walker, W.E.3    Fikrig, E.4
  • 27
    • 0037007625 scopus 로고    scopus 로고
    • Extensive and divergent circadian gene expression in liver and heart
    • Storch, K. F. et al. Extensive and divergent circadian gene expression in liver and heart. Nature 417, 78-83 (2002).
    • (2002) Nature , vol.417 , pp. 78-83
    • Storch, K.F.1
  • 28
    • 84885573359 scopus 로고    scopus 로고
    • Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes
    • Nguyen, K. D. et al. Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes. Science 341, 1483-1488 (2013).
    • (2013) Science , vol.341 , pp. 1483-1488
    • Nguyen, K.D.1
  • 29
    • 84883497410 scopus 로고    scopus 로고
    • Respiratory infections in early life and the development of islet autoimmunity in children at increased type 1 diabetes risk: Evidence from the BABYDIET Study
    • Beyerlein, A., Wehweck, F., Ziegler, A. G. & Pflueger, M. Respiratory infections in early life and the development of islet autoimmunity in children at increased type 1 diabetes risk: evidence from the BABYDIET Study. JAMA Pediatr. 167, 800-807 (2013).
    • (2013) JAMA Pediatr , vol.167 , pp. 800-807
    • Beyerlein, A.1    Wehweck, F.2    Ziegler, A.G.3    Pflueger, M.4
  • 30
    • 16244408025 scopus 로고    scopus 로고
    • Coupling of human circadian and cell cycles by the timeless protein
    • Unsal-Kacmaz, K., Mullen, T. E., Kaufmann, W. K. & Sancar, A. Coupling of human circadian and cell cycles by the timeless protein. Mol.Cell Biol. 25, 3109-3116 (2005).
    • (2005) Mol.Cell Biol , vol.25 , pp. 3109-3116
    • Unsal-Kacmaz, K.1    Mullen, T.E.2    Kaufmann, W.K.3    Sancar, A.4
  • 31
    • 84887275003 scopus 로고    scopus 로고
    • TH17 cell differentiation is regulated by the circadian clock
    • Yu, X. et al. TH17 cell differentiation is regulated by the circadian clock. Science 342, 727-730 (2013).
    • (2013) Science , vol.342 , pp. 727-730
    • Yu, X.1
  • 32
    • 0031862891 scopus 로고    scopus 로고
    • Anti-inflammatory actions of glucocorticoids: Molecular mechanisms
    • Barnes, P. J. Anti-inflammatory actions of glucocorticoids: molecular mechanisms. Clin. Sci. 94, 557-572 (1998).
    • (1998) Clin. Sci , vol.94 , pp. 557-572
    • Barnes, P.J.1
  • 33
    • 84255206549 scopus 로고    scopus 로고
    • Cryptochromes mediate rhythmic repression of the glucocorticoid receptor
    • Lamia, K. A. et al. Cryptochromes mediate rhythmic repression of the glucocorticoid receptor. Nature 480, 552-556 (2011).
    • (2011) Nature , vol.480 , pp. 552-556
    • Lamia, K.A.1
  • 34
    • 79960309646 scopus 로고    scopus 로고
    • Pathways activated during human asthma exacerbation as revealed by gene expression patterns in blood
    • Bjornsdottir, U. S. et al. Pathways activated during human asthma exacerbation as revealed by gene expression patterns in blood. PloS ONE 6, e21902 (2011).
    • (2011) PloS ONE , vol.6
    • Bjornsdottir, U.S.1
  • 35
    • 84903188015 scopus 로고    scopus 로고
    • A type i interferon transcriptional signature precedes autoimmunity in children genetically at-risk of type 1 diabetes
    • Ferreira, R. C. et al. A type I interferon transcriptional signature precedes autoimmunity in children genetically at-risk of type 1 diabetes. Diabetes 63, 2538-2550 (2014).
    • (2014) Diabetes , vol.63 , pp. 2538-2550
    • Ferreira, R.C.1
  • 36
    • 2542488342 scopus 로고    scopus 로고
    • Are humans seasonally photoperiodic?
    • Bronson, F. H. Are humans seasonally photoperiodic? J. Biol. Rhythms 19, 180-192 (2004).
    • (2004) J. Biol. Rhythms , vol.19 , pp. 180-192
    • Bronson, F.H.1
  • 37
    • 33847330324 scopus 로고    scopus 로고
    • Estrogen receptor alpha regulates expression of the breast cancer 1 associated ring domain 1 (BARD1) gene through intronic DNA sequence
    • Creekmore, A. L., Ziegler, Y. S., Boney, J. L. & Nardulli, A. M. Estrogen receptor alpha regulates expression of the breast cancer 1 associated ring domain 1 (BARD1) gene through intronic DNA sequence. Mol.Cell Endocrinol. 267, 106-115 (2007).
    • (2007) Mol.Cell Endocrinol , vol.267 , pp. 106-115
    • Creekmore, A.L.1    Ziegler, Y.S.2    Boney, J.L.3    Nardulli, A.M.4
  • 38
    • 67749112023 scopus 로고    scopus 로고
    • Deconvolution of blood microarray data identifies cellular activation patterns in systemic lupus erythematosus
    • Abbas, A. R., Wolslegel, K., Seshasayee, D., Modrusan, Z. & Clark, H. F. Deconvolution of blood microarray data identifies cellular activation patterns in systemic lupus erythematosus. PLoS ONE 4, e6098 (2009).
    • (2009) PLoS ONE , vol.4
    • Abbas, A.R.1    Wolslegel, K.2    Seshasayee, D.3    Modrusan, Z.4    Clark, H.F.5
  • 39
    • 84898790496 scopus 로고    scopus 로고
    • Seasonal changes in gene expression represent cell-type composition in whole blood
    • De Jong, S. et al. Seasonal changes in gene expression represent cell-type composition in whole blood. Hum. Mol. Genet. 23, 2721-2728 (2014).
    • (2014) Hum. Mol. Genet , vol.23 , pp. 2721-2728
    • De Jong, S.1
  • 40
    • 33749026923 scopus 로고    scopus 로고
    • Effect of month of vaccine administration on antibody responses in the Gambia and Pakistan
    • Moore, S. E. et al. Effect of month of vaccine administration on antibody responses in The Gambia and Pakistan. Trop. Med. Int. Health 11, 1529-1541 (2006).
    • (2006) Trop. Med. Int. Health , vol.11 , pp. 1529-1541
    • Moore, S.E.1
  • 41
    • 84875921547 scopus 로고    scopus 로고
    • Spatio-temporal malaria transmission patterns in Navrongo demographic surveillance site, northern Ghana
    • Kasasa, S. et al. Spatio-temporal malaria transmission patterns in Navrongo demographic surveillance site, northern Ghana. Malaria J. 12, 63 (2013).
    • (2013) Malaria J , vol.12 , pp. 63
    • Kasasa, S.1
  • 42
    • 0033060864 scopus 로고    scopus 로고
    • Early expression and high prevalence of islet autoantibodies for DR3/4 heterozygous and DR4/4 homozygous offspring of parents with Type i diabetes: The German BABYDIAB study
    • Schenker, M. et al. Early expression and high prevalence of islet autoantibodies for DR3/4 heterozygous and DR4/4 homozygous offspring of parents with Type I diabetes: the German BABYDIAB study. Diabetologia 42, 671-677 (1999).
    • (1999) Diabetologia , vol.42 , pp. 671-677
    • Schenker, M.1
  • 43
    • 0034960582 scopus 로고    scopus 로고
    • Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation
    • Hurst, S. M. et al. Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity 14, 705-714 (2001).
    • (2001) Immunity , vol.14 , pp. 705-714
    • Hurst, S.M.1
  • 44
    • 0035164602 scopus 로고    scopus 로고
    • The soluble interleukin 6 receptor: Mechanisms of production and implications in disease
    • Jones, S. A., Horiuchi, S., Topley, N., Yamamoto, N. & Fuller, G. M. The soluble interleukin 6 receptor: mechanisms of production and implications in disease. FASEB J. 15, 43-58 (2001).
    • (2001) FASEB J , vol.15 , pp. 43-58
    • Jones, S.A.1    Horiuchi, S.2    Topley, N.3    Yamamoto, N.4    Fuller, G.M.5
  • 45
    • 84876828211 scopus 로고    scopus 로고
    • Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases
    • Ferreira, R. C. et al. Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases. PLoS Genet. 9, e1003444 (2013).
    • (2013) PLoS Genet , vol.9
    • Ferreira, R.C.1
  • 46
    • 52149099504 scopus 로고    scopus 로고
    • IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: Results from a 24-week multicentre randomised placebo-controlled trial
    • Emery, P. et al. IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial. Ann. Rheum. Dis. 67, 1516-1523 (2008).
    • (2008) Ann. Rheum. Dis , vol.67 , pp. 1516-1523
    • Emery, P.1
  • 47
    • 80052399113 scopus 로고    scopus 로고
    • Rheumatoid arthritis: Circadian and circannual rhythms in RA
    • Cutolo, M. Rheumatoid arthritis: circadian and circannual rhythms in RA. Nat. Rev. Rheumatol. 7, 500-502 (2011).
    • (2011) Nat. Rev. Rheumatol , vol.7 , pp. 500-502
    • Cutolo, M.1
  • 48
    • 31444451575 scopus 로고    scopus 로고
    • Environmental triggers and determinants of type 1 diabetes
    • Knip, M. et al. Environmental triggers and determinants of type 1 diabetes. Diabetes 54(Suppl 2): S125-S136 (2005).
    • (2005) Diabetes , vol.54 , pp. S125-S136
    • Knip, M.1
  • 49
    • 0033081409 scopus 로고    scopus 로고
    • The physiological structure of human C-reactive protein and its complex with phosphocholine
    • Thompson, D., Pepys, M. B. & Wood, S. P. The physiological structure of human C-reactive protein and its complex with phosphocholine. Structure 7, 169-177 (1999).
    • (1999) Structure , vol.7 , pp. 169-177
    • Thompson, D.1    Pepys, M.B.2    Wood, S.P.3
  • 50
    • 57849085182 scopus 로고    scopus 로고
    • Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans
    • Querec, T. D. et al. Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans. Nat. Immunol. 10, 116-125 (2009).
    • (2009) Nat. Immunol , vol.10 , pp. 116-125
    • Querec, T.D.1
  • 51
    • 84896345445 scopus 로고    scopus 로고
    • Molecular signatures of antibody responses derived from a systems biology study of five human vaccines
    • Li, S. et al. Molecular signatures of antibody responses derived from a systems biology study of five human vaccines. Nat. Immunol. 15, 195-204 (2014).
    • (2014) Nat. Immunol , vol.15 , pp. 195-204
    • Li, S.1
  • 52
    • 80051989398 scopus 로고    scopus 로고
    • Systems biology of vaccination for seasonal influenza in humans
    • Nakaya, H. I. et al. Systems biology of vaccination for seasonal influenza in humans. Nat. Immunol. 12, 786-795 (2011).
    • (2011) Nat. Immunol , vol.12 , pp. 786-795
    • Nakaya, H.I.1
  • 53
    • 84866871814 scopus 로고    scopus 로고
    • Mapping cis- and trans-regulatory effects across multiple tissues in twins
    • Grundberg, E. et al. Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat. Genet. 44, 1084-1089 (2012).
    • (2012) Nat. Genet , vol.44 , pp. 1084-1089
    • Grundberg, E.1
  • 54
    • 0030735542 scopus 로고    scopus 로고
    • Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo
    • Mohamed-Ali, V. et al. Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo. J. Clin. Endocrinol. Metab. 82, 4196-4200 (1997).
    • (1997) J. Clin. Endocrinol. Metab , vol.82 , pp. 4196-4200
    • Mohamed-Ali, V.1
  • 55
    • 84929162992 scopus 로고    scopus 로고
    • The genetic architecture of the human immune system: A bioresource for autoimmunity and disease pathogenesis
    • Roederer, M. et al. The genetic architecture of the human immune system: a bioresource for autoimmunity and disease pathogenesis. Cell 161, 387-403 (2015).
    • (2015) Cell , vol.161 , pp. 387-403
    • Roederer, M.1
  • 56
    • 84884878742 scopus 로고    scopus 로고
    • Genetic variants regulating immune cell levels in health and disease
    • Orru, V. et al. Genetic variants regulating immune cell levels in health and disease. Cell 155, 242-256 (2013).
    • (2013) Cell , vol.155 , pp. 242-256
    • Orru, V.1
  • 57
    • 84874056953 scopus 로고    scopus 로고
    • ELevated c-reactive protein levels psychological distress and depression in 73 131 individuals
    • Wium-Andersen, M., Ørsted, D., Nielsen, S. & Nordestgaard, B. ELevated c-reactive protein levels, psychological distress, and depression in 73 131 individuals. JAMA Psychiatry 70, 176-184 (2013).
    • (2013) JAMA Psychiatry , vol.70 , pp. 176-184
    • Wium-Andersen, M.1    Ørsted, D.2    Nielsen, S.3    Nordestgaard, B.4
  • 58
    • 84907776303 scopus 로고    scopus 로고
    • Association of serum interleukin 6 and c-reactive protein in childhood with depression and psychosis in young adult life: A population-based longitudinal study
    • Khandaker, G. M., Pearson, R. M., Zammit, S., Lewis, G. & Jones, P. B. Association of serum interleukin 6 and c-reactive protein in childhood with depression and psychosis in young adult life: A population-based longitudinal study. JAMA Psychiatry 71, 1121-1128 (2014).
    • (2014) JAMA Psychiatry , vol.71 , pp. 1121-1128
    • Khandaker, G.M.1    Pearson, R.M.2    Zammit, S.3    Lewis, G.4    Jones, P.B.5
  • 59
    • 84879966712 scopus 로고    scopus 로고
    • A systems analysis identifies a feedforward inflammatory circuit leading to lethal influenza infection
    • Brandes, M., Klauschen, F., Kuchen, S. & Germain, R. N. A systems analysis identifies a feedforward inflammatory circuit leading to lethal influenza infection. Cell 154, 197-212 (2013).
    • (2013) Cell , vol.154 , pp. 197-212
    • Brandes, M.1    Klauschen, F.2    Kuchen, S.3    Germain, R.N.4
  • 60
    • 84885623978 scopus 로고    scopus 로고
    • Mice genetically deficient in vasopressin V1a and V1b receptors are resistant to jet lag
    • Yamaguchi, Y. et al. Mice genetically deficient in vasopressin V1a and V1b receptors are resistant to jet lag. Science 342, 85-90 (2013).
    • (2013) Science , vol.342 , pp. 85-90
    • Yamaguchi, Y.1
  • 61
    • 0037136537 scopus 로고    scopus 로고
    • The effect of infections on susceptibility to autoimmune and allergic diseases
    • Bach, J. F. The effect of infections on susceptibility to autoimmune and allergic diseases. N. Engl. J. Med. 347, 911-920 (2002).
    • (2002) N. Engl. J. Med , vol.347 , pp. 911-920
    • Bach, J.F.1
  • 62
    • 84893836563 scopus 로고    scopus 로고
    • Mistimed sleep disrupts circadian regulation of the human transcriptome
    • Archer, S. N. et al. Mistimed sleep disrupts circadian regulation of the human transcriptome. Proc. Natl Acad. Sci. USA 111, E682-E691 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. E682-E691
    • Archer, S.N.1
  • 63
    • 0021890408 scopus 로고
    • Melatonin: A coordinating signal for mammalian reproduction?
    • Tamarkin, L., Baird, C. J. & Almeida, O. F. Melatonin: a coordinating signal for mammalian reproduction? Science 227, 714-720 (1985).
    • (1985) Science , vol.227 , pp. 714-720
    • Tamarkin, L.1    Baird, C.J.2    Almeida, O.F.3
  • 64
    • 77949472878 scopus 로고    scopus 로고
    • A circadian clock is not required in an arctic mammal
    • Lu, W., Meng, Q. J., Tyler, N. J., Stokkan, K. A. & Loudon, A. S. A circadian clock is not required in an arctic mammal. Curr. Biol. 20, 533-537 (2010).
    • (2010) Curr. Biol , vol.20 , pp. 533-537
    • Lu, W.1    Meng, Q.J.2    Tyler, N.J.3    Stokkan, K.A.4    Loudon, A.S.5
  • 65
    • 84904040901 scopus 로고    scopus 로고
    • A circannual clock drives expression of genes central for seasonal reproduction
    • Saenz de Miera, C. et al. A circannual clock drives expression of genes central for seasonal reproduction. Curr. Biol. 24, 1500-1506 (2014).
    • (2014) Curr. Biol , vol.24 , pp. 1500-1506
    • Saenz De Miera, C.1
  • 66
    • 84877145117 scopus 로고    scopus 로고
    • Genome wide association study of age at menarche in the Japanese population
    • Tanikawa, C. et al. Genome wide association study of age at menarche in the Japanese population. PloS ONE 8, e63821 (2013).
    • (2013) PloS ONE , vol.8
    • Tanikawa, C.1
  • 67
    • 84908024873 scopus 로고    scopus 로고
    • Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
    • Perry, J. R. et al. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature 514, 92-97 (2014).
    • (2014) Nature , vol.514 , pp. 92-97
    • Perry, J.R.1
  • 68
    • 66549115458 scopus 로고    scopus 로고
    • Serum amyloid A, C-reactive protein, and retinal microvascular changes in hypertensive diabetic and nondiabetic individuals: An Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) substudy
    • Stettler, C. et al. Serum amyloid A, C-reactive protein, and retinal microvascular changes in hypertensive diabetic and nondiabetic individuals: an Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) substudy. Diabetes Care 32, 1098-1100 (2009).
    • (2009) Diabetes Care , vol.32 , pp. 1098-1100
    • Stettler, C.1
  • 69
    • 60549111634 scopus 로고    scopus 로고
    • WGCNA: An R package for weighted correlation network analysis
    • Langfelder, P. & Horvath, S. WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics 9, 559 (2008).
    • (2008) BMC Bioinformatics , vol.9 , pp. 559
    • Langfelder, P.1    Horvath, S.2
  • 70
    • 84880617636 scopus 로고    scopus 로고
    • WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): Update 2013
    • Wang, J., Duncan, D., Shi, Z. & Zhang, B. WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013. Nucleic Acids Res. 41, W77-W83 (2013).
    • (2013) Nucleic Acids Res , vol.41 , pp. W77-W83
    • Wang, J.1    Duncan, D.2    Shi, Z.3    Zhang, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.