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Volumn 58, Issue 1, 2017, Pages 90-105

Murine models of sepsis and trauma: Can We bridge the gap?

Author keywords

Animal models; Inflammation; Mouse; Murine; Sepsis; Shock; Translational research; Trauma

Indexed keywords

ANIMAL; DISEASE MODEL; HUMAN; IMMUNOLOGY; INJURY; MOUSE; PATHOLOGY; SEPSIS;

EID: 85028360017     PISSN: 10842020     EISSN: 19306180     Source Type: Journal    
DOI: 10.1093/ilar/ilx007     Document Type: Article
Times cited : (118)

References (121)
  • 1
    • 0028924980 scopus 로고
    • Differential expression of interferon regulatory factor 1 (IRF-1), IRF-2, and interferon consensus sequence binding protein genes in lipopolysaccharide (LPS)-responsive and LPS-hyporesponsive macrophages
    • Barber SA, Fultz MJ, Salkowski CA, Vogel SN. 1995. Differential expression of interferon regulatory factor 1 (IRF-1), IRF-2, and interferon consensus sequence binding protein genes in lipopolysaccharide (LPS)-responsive and LPS-hyporesponsive macrophages. Infect Immun 63(2):601-608.
    • (1995) Infect Immun , vol.63 , Issue.2 , pp. 601-608
    • Barber, S.A.1    Fultz, M.J.2    Salkowski, C.A.3    Vogel, S.N.4
  • 3
    • 0034769118 scopus 로고    scopus 로고
    • Nitric oxide and the immune response
    • Bogdan C. 2001. Nitric oxide and the immune response. Nat Immunol 2(10):907-916.
    • (2001) Nat Immunol , vol.2 , Issue.10 , pp. 907-916
    • Bogdan, C.1
  • 4
    • 78549232989 scopus 로고    scopus 로고
    • Helicopters and the civilian trauma system: National utilization patterns demonstrate improved outcomes after traumatic injury
    • discussion 1034-1036
    • Brown JB, Stassen NA, Bankey PE, Sangosanya AT, Cheng JD, Gestring ML. 2010. Helicopters and the civilian trauma system: National utilization patterns demonstrate improved outcomes after traumatic injury. J Trauma 69(5):1030-1034; discussion 1034-1036.
    • (2010) J Trauma , vol.69 , Issue.5 , pp. 1030-1034
    • Brown, J.B.1    Stassen, N.A.2    Bankey, P.E.3    Sangosanya, A.T.4    Cheng, J.D.5    Gestring, M.L.6
  • 8
    • 0031938868 scopus 로고    scopus 로고
    • Adaptation of the fluid percussion injury model to the mouse
    • Carbonell WS, Maris DO, McCall T, Grady MS. 1998. Adaptation of the fluid percussion injury model to the mouse. J Neurotrauma 15(3):217-229.
    • (1998) J Neurotrauma , vol.15 , Issue.3 , pp. 217-229
    • Carbonell, W.S.1    Maris, D.O.2    McCall, T.3    Grady, M.S.4
  • 10
    • 0029671119 scopus 로고    scopus 로고
    • Ageassociated differences in TNF-alpha and nitric oxide production in endotoxic mice
    • Chorinchath BB, Kong LY, Mao L, McCallum RE. 1996. Ageassociated differences in TNF-alpha and nitric oxide production in endotoxic mice. J Immunol 156(4):1525-1530.
    • (1996) J Immunol , vol.156 , Issue.4 , pp. 1525-1530
    • Chorinchath, B.B.1    Kong, L.Y.2    Mao, L.3    McCallum, R.E.4
  • 11
    • 0035105387 scopus 로고    scopus 로고
    • Laparotomy potentiates cytokine release and impairs pulmonary function after hemorrhage and resuscitation in mice
    • Claridge JA, Weed AC, Enelow R, Young JS. 2001. Laparotomy potentiates cytokine release and impairs pulmonary function after hemorrhage and resuscitation in mice. J Trauma 50(2):244-252.
    • (2001) J Trauma , vol.50 , Issue.2 , pp. 244-252
    • Claridge, J.A.1    Weed, A.C.2    Enelow, R.3    Young, J.S.4
  • 13
    • 84893351797 scopus 로고    scopus 로고
    • Policy: NIH plans to enhance reproducibility
    • Collins FS, Tabak LA. 2014. Policy: NIH plans to enhance reproducibility. Nature 505(7485):612-613.
    • (2014) Nature , vol.505 , Issue.7485 , pp. 612-613
    • Collins, F.S.1    Tabak, L.A.2
  • 14
    • 12544254834 scopus 로고    scopus 로고
    • Acute inflammatory response to endotoxin in mice and humans
    • Copeland S, Warren HS, Lowry SF, Calvano SE, Remick DInflammation, the Host Response to Injury I. 2005. Acute inflammatory response to endotoxin in mice and humans. Clin Diagn Lab Immunol 12(1):60-67.
    • (2005) Clin Diagn Lab Immunol , vol.12 , Issue.1 , pp. 60-67
    • Copeland, S.1    Warren, H.S.2    Lowry, S.F.3    Calvano, S.E.4
  • 16
    • 0027281370 scopus 로고
    • Choice of bacteria in animal models of sepsis
    • Cross AS, Opal SM, Sadoff JC, Gemski P. 1993. Choice of bacteria in animal models of sepsis. Infect Immun 61(7):2741-2747.
    • (1993) Infect Immun , vol.61 , Issue.7 , pp. 2741-2747
    • Cross, A.S.1    Opal, S.M.2    Sadoff, J.C.3    Gemski, P.4
  • 18
    • 0030929805 scopus 로고    scopus 로고
    • Fc receptor biology
    • Daeron M. 1997. Fc receptor biology. Annu Rev Immunol 15: 203-234.
    • (1997) Annu Rev Immunol , vol.15 , pp. 203-234
    • Daeron, M.1
  • 20
    • 11844267259 scopus 로고    scopus 로고
    • Genetic determinants influencing the response to injury, inflammation, and sepsis
    • De Maio A, Torres MB, Reeves RH. 2005. Genetic determinants influencing the response to injury, inflammation, and sepsis. Shock 23(1):11-17.
    • (2005) Shock , vol.23 , Issue.1 , pp. 11-17
    • De Maio, A.1    Torres, M.B.2    Reeves, R.H.3
  • 21
    • 0031606321 scopus 로고    scopus 로고
    • Animal models of sepsis and shock: A review and lessons learned
    • Deitch EA. 1998. Animal models of sepsis and shock: A review and lessons learned. Shock 9(1):1-11.
    • (1998) Shock , vol.9 , Issue.1 , pp. 1-11
    • Deitch, E.A.1
  • 23
    • 1342277259 scopus 로고    scopus 로고
    • Gender dimorphism in differential peripheral blood leukocyte counts in mice using cardiac, tail, foot, and saphenous vein puncture methods
    • Doeing DC, Borowicz JL, Crockett ET. 2003. Gender dimorphism in differential peripheral blood leukocyte counts in mice using cardiac, tail, foot, and saphenous vein puncture methods. BMC Clin Pathol 3(1):3.
    • (2003) BMC Clin Pathol , vol.3 , Issue.1 , pp. 3
    • Doeing, D.C.1    Borowicz, J.L.2    Crockett, E.T.3
  • 24
    • 84949033387 scopus 로고    scopus 로고
    • Men and mice: Relating their ages
    • Dutta S, Sengupta P. 2016. Men and mice: Relating their ages. Life Sci 152:244-248.
    • (2016) Life Sci , vol.152 , pp. 244-248
    • Dutta, S.1    Sengupta, P.2
  • 25
    • 58849093274 scopus 로고    scopus 로고
    • Animal models of sepsis: Why does preclinical efficacy fail to translate to the clinical setting?
    • Dyson A, Singer M. 2009. Animal models of sepsis: Why does preclinical efficacy fail to translate to the clinical setting? Crit Care Med 37(1 Suppl):S30-S37.
    • (2009) Crit Care Med , vol.37 , Issue.1 , pp. S30-S37
    • Dyson, A.1    Singer, M.2
  • 26
    • 84940117266 scopus 로고    scopus 로고
    • The future of murine sepsis and trauma research models
    • Efron PA, Mohr AM, Moore FA, Moldawer LL. 2015. The future of murine sepsis and trauma research models. J Leukoc Biol 98 (6):945-952.
    • (2015) J Leukoc Biol , vol.98 , Issue.6 , pp. 945-952
    • Efron, P.A.1    Mohr, A.M.2    Moore, F.A.3    Moldawer, L.L.4
  • 27
    • 85010430759 scopus 로고    scopus 로고
    • Incidence and etiology of mortality in polytrauma patients in a Dutch level I trauma center
    • El Mestoui Z, Jalalzadeh H, Giannakopoulos GF, Zuidema WP. 2015. Incidence and etiology of mortality in polytrauma patients in a Dutch level I trauma center. Eur J Emerg Med 24 (1):49-54.
    • (2015) Eur J Emerg Med , vol.24 , Issue.1 , pp. 49-54
    • El Mestoui, Z.1    Jalalzadeh, H.2    Giannakopoulos, G.F.3    Zuidema, W.P.4
  • 28
    • 0035159584 scopus 로고    scopus 로고
    • Distinct T cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of ZAP-70
    • Elder ME, Skoda-Smith S, Kadlecek TA, Wang F, Wu J, Weiss A. 2001. Distinct T cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of ZAP-70. J Immunol 166(1):656-661.
    • (2001) J Immunol , vol.166 , Issue.1 , pp. 656-661
    • Elder, M.E.1    Skoda-Smith, S.2    Kadlecek, T.A.3    Wang, F.4    Wu, J.5    Weiss, A.6
  • 29
    • 85006066279 scopus 로고    scopus 로고
    • Mouse Genome Informatics (MGI): resources for mining mouse genetic, genomic, and biological data in support of primary and translational research
    • Eppig JT, Smith CL, Blake JA, Ringwald M, Kadin JA, Richardson JE, Bult CJ. 2017. Mouse Genome Informatics (MGI): resources for mining mouse genetic, genomic, and biological data in support of primary and translational research. Methods Mol Biol 1488:47-73.
    • (2017) Methods Mol Biol , vol.1488 , pp. 47-73
    • Eppig, J.T.1    Smith, C.L.2    Blake, J.A.3    Ringwald, M.4    Kadin, J.A.5    Richardson, J.E.6    Bult, C.J.7
  • 30
    • 0034231339 scopus 로고    scopus 로고
    • Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2
    • Farrar JD, Smith JD, Murphy TL, Leung S, Stark GR, Murphy KM. 2000. Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2. Nat Immunol 1(1):65-69.
    • (2000) Nat Immunol , vol.1 , Issue.1 , pp. 65-69
    • Farrar, J.D.1    Smith, J.D.2    Murphy, T.L.3    Leung, S.4    Stark, G.R.5    Murphy, K.M.6
  • 31
    • 84890861186 scopus 로고    scopus 로고
    • Animal models of sepsis
    • Fink MP. 2014. Animal models of sepsis. Virulence 5(1):143-153.
    • (2014) Virulence , vol.5 , Issue.1 , pp. 143-153
    • Fink, M.P.1
  • 32
    • 0025354406 scopus 로고
    • Laboratory models of sepsis and septic shock
    • Fink MP, Heard SO. 1990. Laboratory models of sepsis and septic shock. J Surg Res 49(2):186-196.
    • (1990) J Surg Res , vol.49 , Issue.2 , pp. 186-196
    • Fink, M.P.1    Heard, S.O.2
  • 33
    • 0022593215 scopus 로고
    • Regional blood flow during continuous low-dose endotoxin infusion
    • Fish RE, Lang CH, Spitzer JA. 1986. Regional blood flow during continuous low-dose endotoxin infusion. Circ Shock 18(4): 267-275.
    • (1986) Circ Shock , vol.18 , Issue.4 , pp. 267-275
    • Fish, R.E.1    Lang, C.H.2    Spitzer, J.A.3
  • 36
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich DI, Nagaraj S. 2009. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 9(3):162-174.
    • (2009) Nat Rev Immunol , vol.9 , Issue.3 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 41
    • 15044359591 scopus 로고    scopus 로고
    • Insights into severe sepsis in older patients: From epidemiology to evidence-based management
    • Girard TD, Opal SM, Ely EW. 2005. Insights into severe sepsis in older patients: From epidemiology to evidence-based management. Clin Infect Dis 40(5):719-727.
    • (2005) Clin Infect Dis , vol.40 , Issue.5 , pp. 719-727
    • Girard, T.D.1    Opal, S.M.2    Ely, E.W.3
  • 43
    • 67649664210 scopus 로고    scopus 로고
    • Advances in the establishment of defined mouse models for the study of fracture healing and bone regeneration
    • Holstein JH, Garcia P, Histing T, Kristen A, Scheuer C, Menger MD, Pohlemann T. 2009. Advances in the establishment of defined mouse models for the study of fracture healing and bone regeneration. J Orthop Trauma 23(5 Suppl):S31-S38.
    • (2009) J Orthop Trauma , vol.23 , Issue.5 , pp. S31-S38
    • Holstein, J.H.1    Garcia, P.2    Histing, T.3    Kristen, A.4    Scheuer, C.5    Menger, M.D.6    Pohlemann, T.7
  • 45
    • 34548668886 scopus 로고    scopus 로고
    • Toll-like receptor 2 participates in the response to lung injury in a murine model of pulmonary contusion
    • Hoth JJ, Hudson WP, Brownlee NA, Yoza BK, Hiltbold EM, Meredith JW, McCall CE. 2007. Toll-like receptor 2 participates in the response to lung injury in a murine model of pulmonary contusion. Shock 28(4):447-452.
    • (2007) Shock , vol.28 , Issue.4 , pp. 447-452
    • Hoth, J.J.1    Hudson, W.P.2    Brownlee, N.A.3    Yoza, B.K.4    Hiltbold, E.M.5    Meredith, J.W.6    McCall, C.E.7
  • 46
    • 84862201892 scopus 로고    scopus 로고
    • Population burden of long-term survivorship after severe sepsis in older Americans
    • Iwashyna TJ, Cooke CR, Wunsch H, Kahn JM. 2012. Population burden of long-term survivorship after severe sepsis in older Americans. J Am Geriatr Soc 60(6):1070-1077.
    • (2012) J Am Geriatr Soc , vol.60 , Issue.6 , pp. 1070-1077
    • Iwashyna, T.J.1    Cooke, C.R.2    Wunsch, H.3    Kahn, J.M.4
  • 47
    • 0031683605 scopus 로고    scopus 로고
    • Transgenic mice in the study of ALS: The role of neurofilaments
    • Julien JP, Couillard-Despres S, Meier J. 1998. Transgenic mice in the study of ALS: The role of neurofilaments. Brain Pathol 8 (4):759-769.
    • (1998) Brain Pathol , vol.8 , Issue.4 , pp. 759-769
    • Julien, J.P.1    Couillard-Despres, S.2    Meier, J.3
  • 49
    • 0036144034 scopus 로고    scopus 로고
    • Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis
    • Knöferl MW, Angele MK, Diodato MD, Schwacha MG, Ayala A, Cioffi WG, Bland KI, Chaudry IH. 2002. Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis. Ann Surg 235(1):105-112.
    • (2002) Ann Surg , vol.235 , Issue.1 , pp. 105-112
    • Knöferl, M.W.1    Angele, M.K.2    Diodato, M.D.3    Schwacha, M.G.4    Ayala, A.5    Cioffi, W.G.6    Bland, K.I.7    Chaudry, I.H.8
  • 50
    • 84455162523 scopus 로고    scopus 로고
    • High tidal volume mechanical ventilation-induced lung injury in rats is greater after acid instillation than after sepsis-induced acute lung injury, but does not increase systemic inflammation: An experimental study
    • Kuiper JW, Plotz FB, Groeneveld AJ, Haitsma JJ, Jothy S, Vaschetto R, Zhang H, Slutsky AS. 2011. High tidal volume mechanical ventilation-induced lung injury in rats is greater after acid instillation than after sepsis-induced acute lung injury, but does not increase systemic inflammation: An experimental study. BMC Anesthesiol 11:26.
    • (2011) BMC Anesthesiol , vol.11 , pp. 26
    • Kuiper, J.W.1    Plotz, F.B.2    Groeneveld, A.J.3    Haitsma, J.J.4    Jothy, S.5    Vaschetto, R.6    Zhang, H.7    Slutsky, A.S.8
  • 54
    • 82055162848 scopus 로고    scopus 로고
    • Transgenic mice as a model for Alzheimer's disease
    • Lithner CU, Hedberg MM, Nordberg A. 2011. Transgenic mice as a model for Alzheimer's disease. Curr Alzheimer Res 8(8):818-831.
    • (2011) Curr Alzheimer Res , vol.8 , Issue.8 , pp. 818-831
    • Lithner, C.U.1    Hedberg, M.M.2    Nordberg, A.3
  • 59
    • 84892960440 scopus 로고    scopus 로고
    • Lost in translation: Animal models and clinical trials in cancer treatment
    • Mak IW, Evaniew N, Ghert M. 2014. Lost in translation: Animal models and clinical trials in cancer treatment. Am J Transl Res 6(2):114-118.
    • (2014) Am J Transl Res , vol.6 , Issue.2 , pp. 114-118
    • Mak, I.W.1    Evaniew, N.2    Ghert, M.3
  • 60
    • 84893637270 scopus 로고    scopus 로고
    • One mouse, one patient paradigm: New avatars of personalized cancer therapy
    • Malaney P, Nicosia SV, Dave V. 2014. One mouse, one patient paradigm: New avatars of personalized cancer therapy. Cancer Lett 344(1):1-12.
    • (2014) Cancer Lett , vol.344 , Issue.1 , pp. 1-12
    • Malaney, P.1    Nicosia, S.V.2    Dave, V.3
  • 61
    • 16644376326 scopus 로고    scopus 로고
    • Characterization of a closed femur fracture model in mice
    • Manigrasso MB, O'Connor JP. 2004. Characterization of a closed femur fracture model in mice. J Orthop Trauma 18(10): 687-695.
    • (2004) J Orthop Trauma , vol.18 , Issue.10 , pp. 687-695
    • Manigrasso, M.B.1    O'Connor, J.P.2
  • 62
    • 84899640120 scopus 로고    scopus 로고
    • Emergency granulopoiesis
    • Manz MG, Boettcher S. 2014. Emergency granulopoiesis. Nat Rev Immunol 14(5):302-314.
    • (2014) Nat Rev Immunol , vol.14 , Issue.5 , pp. 302-314
    • Manz, M.G.1    Boettcher, S.2
  • 64
    • 0031602351 scopus 로고    scopus 로고
    • Is IgG2a a good Th1 marker in mice?
    • Martin RM, Lew AM. 1998. Is IgG2a a good Th1 marker in mice? Immunol Today 19(1):49.
    • (1998) Immunol Today , vol.19 , Issue.1 , pp. 49
    • Martin, R.M.1    Lew, A.M.2
  • 66
    • 0034830650 scopus 로고    scopus 로고
    • Essential role for estrogen in protection against Vibrio vulnificus-induced endotoxic shock
    • Merkel SM, Alexander S, Zufall E, Oliver JD, Huet-Hudson YM. 2001. Essential role for estrogen in protection against Vibrio vulnificus-induced endotoxic shock. Infect Immun 69(10): 6119-6122.
    • (2001) Infect Immun , vol.69 , Issue.10 , pp. 6119-6122
    • Merkel, S.M.1    Alexander, S.2    Zufall, E.3    Oliver, J.D.4    Huet-Hudson, Y.M.5
  • 67
    • 1342303482 scopus 로고    scopus 로고
    • Of mice and not men: Differences between mouse and human immunology
    • Mestas J, Hughes CC. 2004. Of mice and not men: Differences between mouse and human immunology. J Immunol 172(5): 2731-2738.
    • (2004) J Immunol , vol.172 , Issue.5 , pp. 2731-2738
    • Mestas, J.1    Hughes, C.C.2
  • 72
    • 77957227475 scopus 로고    scopus 로고
    • Model organisms-A historical perspective
    • Muller B, Grossniklaus U. 2010. Model organisms-A historical perspective. J Proteomics 73(11):2054-2063.
    • (2010) J Proteomics , vol.73 , Issue.11 , pp. 2054-2063
    • Muller, B.1    Grossniklaus, U.2
  • 75
    • 84980126487 scopus 로고
    • A quantitative method for the production of experimental traumatic shock without h ae morrhage in unanaesthetized animals
    • Noble RL, Collip JB. 1942. A quantitative method for the production of experimental traumatic shock without h ae morrhage in unanaesthetized animals. Q J Exp Physiol Cogn Med Sci 31:187-199.
    • (1942) Q J Exp Physiol Cogn Med Sci , vol.31 , pp. 187-199
    • Noble, R.L.1    Collip, J.B.2
  • 77
    • 0035152225 scopus 로고    scopus 로고
    • Experimental models of gramnegative sepsis
    • Parker SJ, Watkins PE. 2001. Experimental models of gramnegative sepsis. Br J Surg 88(1):22-30.
    • (2001) Br J Surg , vol.88 , Issue.1 , pp. 22-30
    • Parker, S.J.1    Watkins, P.E.2
  • 78
    • 57549093082 scopus 로고    scopus 로고
    • Creation of "humanized" mice to study human immunity
    • Chapter 15:Unit 15.21.
    • Pearson T, Greiner DL, Shultz LD. 2008. Creation of "humanized" mice to study human immunity. Curr Protoc Immunol Chapter 15:Unit 15.21.
    • (2008) Curr Protoc Immunol
    • Pearson, T.1    Greiner, D.L.2    Shultz, L.D.3
  • 80
    • 70350050250 scopus 로고    scopus 로고
    • Breeding and housing laboratory rats and mice in the same room does not affect the growth or reproduction of either species
    • Pritchett-Corning KR, Chang FT, Festing MF. 2009. Breeding and housing laboratory rats and mice in the same room does not affect the growth or reproduction of either species. J Am Assoc Lab Anim Sci 48(5):492-498.
    • (2009) J Am Assoc Lab Anim Sci , vol.48 , Issue.5 , pp. 492-498
    • Pritchett-Corning, K.R.1    Chang, F.T.2    Festing, M.F.3
  • 82
    • 0026695229 scopus 로고
    • Protective effects of preheparinization on the microvasculature during and after hemorrhagic shock
    • Rana MW, Singh G, Wang P, Ayala A, Zhou M, Chaudry IH. 1992. Protective effects of preheparinization on the microvasculature during and after hemorrhagic shock. J Trauma 32(4): 420-426.
    • (1992) J Trauma , vol.32 , Issue.4 , pp. 420-426
    • Rana, M.W.1    Singh, G.2    Wang, P.3    Ayala, A.4    Zhou, M.5    Chaudry, I.H.6
  • 83
    • 0028358843 scopus 로고
    • In vivo characterization of zymosan-induced mouse peritoneal inflammation
    • Rao TS, Currie JL, Shaffer AF, Isakson PC. 1994. In vivo characterization of zymosan-induced mouse peritoneal inflammation. J Pharmacol Exp Ther 269(3):917-925.
    • (1994) J Pharmacol Exp Ther , vol.269 , Issue.3 , pp. 917-925
    • Rao, T.S.1    Currie, J.L.2    Shaffer, A.F.3    Isakson, P.C.4
  • 84
    • 0034132796 scopus 로고    scopus 로고
    • Comparison of the mortality and inflammatory response of two models of sepsis: Lipopolysaccharide vs
    • Remick DG, Newcomb DE, Bolgos GL, Call DR. 2000. Comparison of the mortality and inflammatory response of two models of sepsis: Lipopolysaccharide vs. cecal ligation and puncture. Shock 13(2):110-116.
    • (2000) cecal ligation and puncture. Shock , vol.13 , Issue.2 , pp. 110-116
    • Remick, D.G.1    Newcomb, D.E.2    Bolgos, G.L.3    Call, D.R.4
  • 86
    • 0033664277 scopus 로고    scopus 로고
    • Leukocyte antimicrobial peptides: Multifunctional effector molecules of innate immunity
    • Risso A. 2000. Leukocyte antimicrobial peptides: Multifunctional effector molecules of innate immunity. J Leukoc Biol 68(6): 785-792.
    • (2000) J Leukoc Biol , vol.68 , Issue.6 , pp. 785-792
    • Risso, A.1
  • 89
    • 0030978084 scopus 로고    scopus 로고
    • Role of gamma interferon in the pathogenesis of bacteremic pneumococcal pneumonia
    • Rubins JB, Pomeroy C. 1997. Role of gamma interferon in the pathogenesis of bacteremic pneumococcal pneumonia. Infect Immun 65(7):2975-2977.
    • (1997) Infect Immun , vol.65 , Issue.7 , pp. 2975-2977
    • Rubins, J.B.1    Pomeroy, C.2
  • 91
    • 84855381793 scopus 로고    scopus 로고
    • Immunological variation between inbred laboratory mouse strains: Points to consider in phenotyping genetically immunomodified mice
    • Sellers RS, Clifford CB, Treuting PM, Brayton C. 2012. Immunological variation between inbred laboratory mouse strains: Points to consider in phenotyping genetically immunomodified mice. Vet Pathol 49(1):32-43.
    • (2012) Vet Pathol , vol.49 , Issue.1 , pp. 32-43
    • Sellers, R.S.1    Clifford, C.B.2    Treuting, P.M.3    Brayton, C.4
  • 93
    • 1542308211 scopus 로고    scopus 로고
    • Interaction between the innate and adaptive immune systems is required to survive sepsis and control inflammation after injury
    • Shelley O, Murphy T, Paterson H, Mannick JA, Lederer JA. 2003. Interaction between the innate and adaptive immune systems is required to survive sepsis and control inflammation after injury. Shock 20(2):123-129.
    • (2003) Shock , vol.20 , Issue.2 , pp. 123-129
    • Shelley, O.1    Murphy, T.2    Paterson, H.3    Mannick, J.A.4    Lederer, J.A.5
  • 94
    • 0003999762 scopus 로고
    • Mouse Genetics: Concepts and Applications
    • Oxford: Oxford University Press.
    • Silver LM. 1995. Mouse Genetics: Concepts and Applications. Oxford: Oxford University Press.
    • (1995)
    • Silver, L.M.1
  • 96
    • 84921727957 scopus 로고    scopus 로고
    • Genomic responses in mouse models greatly mimic human inflammatory diseases
    • Takao K, Miyakawa T. 2015. Genomic responses in mouse models greatly mimic human inflammatory diseases. Proc Natl Acad Sci USA 112(4):1167-1172.
    • (2015) Proc Natl Acad Sci USA , vol.112 , Issue.4 , pp. 1167-1172
    • Takao, K.1    Miyakawa, T.2
  • 97
    • 0030038450 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced lethality and cytokine production in aged mice
    • Tateda K, Matsumoto T, Miyazaki S, Yamaguchi K. 1996. Lipopolysaccharide-induced lethality and cytokine production in aged mice. Infect Immun 64(3):769-774.
    • (1996) Infect Immun , vol.64 , Issue.3 , pp. 769-774
    • Tateda, K.1    Matsumoto, T.2    Miyazaki, S.3    Yamaguchi, K.4
  • 99
    • 84928584867 scopus 로고    scopus 로고
    • Impact of obesity on sepsis mortality: A systematic review
    • Trivedi V, Bavishi C, Jean R. 2015. Impact of obesity on sepsis mortality: A systematic review. J Crit Care 30(3):518-524.
    • (2015) J Crit Care , vol.30 , Issue.3 , pp. 518-524
    • Trivedi, V.1    Bavishi, C.2    Jean, R.3
  • 101
    • 58849151806 scopus 로고    scopus 로고
    • Animal models for trauma research: what are the options?
    • Tsukamoto T, Pape HC. 2009. Animal models for trauma research: what are the options? Shock 31(1):3-10.
    • (2009) Shock , vol.31 , Issue.1 , pp. 3-10
    • Tsukamoto, T.1    Pape, H.C.2
  • 104
    • 69449084286 scopus 로고    scopus 로고
    • Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice
    • Unsinger J, McDonough JS, Shultz LD, Ferguson TA, Hotchkiss RS. 2009. Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice. J Leukoc Biol 86 (2):219-227.
    • (2009) J Leukoc Biol , vol.86 , Issue.2 , pp. 219-227
    • Unsinger, J.1    McDonough, J.S.2    Shultz, L.D.3    Ferguson, T.A.4    Hotchkiss, R.S.5
  • 105
    • 84869840966 scopus 로고    scopus 로고
    • Preclinical sepsis models
    • van der Poll T. 2012. Preclinical sepsis models. Surg Infect (Larchmt) 13(5):287-292.
    • (2012) Surg Infect (Larchmt) , vol.13 , Issue.5 , pp. 287-292
    • van der Poll, T.1
  • 107
    • 16244372427 scopus 로고    scopus 로고
    • Zymosan-induced generalized inflammation: Experimental studies into mechanisms leading to multiple organ dysfunction syndrome
    • Volman TJ, Hendriks T, Goris RJ. 2005. Zymosan-induced generalized inflammation: Experimental studies into mechanisms leading to multiple organ dysfunction syndrome. Shock 23(4):291-297.
    • (2005) Shock , vol.23 , Issue.4 , pp. 291-297
    • Volman, T.J.1    Hendriks, T.2    Goris, R.J.3
  • 108
    • 0025094416 scopus 로고
    • Tumour necrosis factor alpha (TNF-alpha) and interleukin 6 in a zymosan-induced shock model
    • von Asmuth EJ, Maessen JG, van der Linden CJ, Buurman WA. 1990. Tumour necrosis factor alpha (TNF-alpha) and interleukin 6 in a zymosan-induced shock model. Scand J Immunol 32(4):313-319.
    • (1990) Scand J Immunol , vol.32 , Issue.4 , pp. 313-319
    • von Asmuth, E.J.1    Maessen, J.G.2    van der Linden, C.J.3    Buurman, W.A.4
  • 109
    • 0027411590 scopus 로고
    • Traumahemorrhage and resuscitation in the mouse: effects on cardiac output and organ blood flow
    • Wang P, Ba ZF, Burkhardt J, Chaudry IH. 1993. Traumahemorrhage and resuscitation in the mouse: effects on cardiac output and organ blood flow. Am J Physiol 264(4 Pt 2): H1166-H1173.
    • (1993) Am J Physiol , vol.264 , Issue.4 , pp. H1166-H1173
    • Wang, P.1    Ba, Z.F.2    Burkhardt, J.3    Chaudry, I.H.4
  • 111
    • 0031784643 scopus 로고    scopus 로고
    • Nitric oxide production and nitric oxide synthase type 2 expression by human mononuclear phagocytes: A review
    • Weinberg JB. 1998. Nitric oxide production and nitric oxide synthase type 2 expression by human mononuclear phagocytes: A review. Mol Med 4(9):557-591.
    • (1998) Mol Med , vol.4 , Issue.9 , pp. 557-591
    • Weinberg, J.B.1
  • 113
    • 0018964280 scopus 로고
    • Sepsis and septic shock-a review of laboratory models and a proposal
    • Wichterman KA, Baue AE, Chaudry IH. 1980. Sepsis and septic shock-a review of laboratory models and a proposal. J Surg Res 29(2):189-201.
    • (1980) J Surg Res , vol.29 , Issue.2 , pp. 189-201
    • Wichterman, K.A.1    Baue, A.E.2    Chaudry, I.H.3
  • 114
    • 0141791248 scopus 로고    scopus 로고
    • High tidal volume upregulates intrapulmonary cytokines in an in vivo mouse model of ventilator-induced lung injury
    • Wilson MR, Choudhury S, Goddard ME, O'Dea KP, Nicholson AG, Takata M. 2003. High tidal volume upregulates intrapulmonary cytokines in an in vivo mouse model of ventilator-induced lung injury. J Appl Physiol (1985) 95(4): 1385-1393.
    • (2003) J Appl Physiol (1985) , vol.95 , Issue.4 , pp. 1385-1393
    • Wilson, M.R.1    Choudhury, S.2    Goddard, M.E.3    O'Dea, K.P.4    Nicholson, A.G.5    Takata, M.6
  • 117
    • 33748072117 scopus 로고    scopus 로고
    • Mechanisms of mortality in early and late sepsis
    • Xiao H, Siddiqui J, Remick DG. 2006. Mechanisms of mortality in early and late sepsis. Infect Immun 74(9):5227-5235.
    • (2006) Infect Immun , vol.74 , Issue.9 , pp. 5227-5235
    • Xiao, H.1    Siddiqui, J.2    Remick, D.G.3
  • 120
    • 0031924789 scopus 로고    scopus 로고
    • Essential role of gamma interferon in survival of colon ascendens stent peritonitis, a novel murine model of abdominal sepsis
    • Zantl N, Uebe A, Neumann B, Wagner H, Siewert JR, Holzmann B, Heidecke CD, Pfeffer K. 1998. Essential role of gamma interferon in survival of colon ascendens stent peritonitis, a novel murine model of abdominal sepsis. Infect Immun 66(5):2300-2309.
    • (1998) Infect Immun , vol.66 , Issue.5 , pp. 2300-2309
    • Zantl, N.1    Uebe, A.2    Neumann, B.3    Wagner, H.4    Siewert, J.R.5    Holzmann, B.6    Heidecke, C.D.7    Pfeffer, K.8
  • 121
    • 0031012356 scopus 로고    scopus 로고
    • Females in proestrus state maintain splenic immune functions and tolerate sepsis better than males
    • Zellweger R, Wichmann MW, Ayala A, Stein S, DeMaso CM, Chaudry IH. 1997. Females in proestrus state maintain splenic immune functions and tolerate sepsis better than males. Crit Care Med 25(1):106-110.
    • (1997) Crit Care Med , vol.25 , Issue.1 , pp. 106-110
    • Zellweger, R.1    Wichmann, M.W.2    Ayala, A.3    Stein, S.4    DeMaso, C.M.5    Chaudry, I.H.6


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