A better understanding of why murine models of trauma do not recapitulate the human syndrome

Critical Care Medicine

Volumn 42, Issue 6, 2014, Pages 1406-1413

  Gentile, Lori F ^a   Nacionales, Dina C ^a   Lopez, M Cecilia ^a   Vanzant, Erin ^a   Cuenca, Angela ^a   Cuenca, Alex G ^a   Ungaro, Ricardo ^a   Baslanti, Tezcan Ozrazgat ^a   McKinley, Bruce A ^a   Bihorac, Azra ^a   Cuschieri, Joseph ^b   Maier, Ronald V ^b   Moore, Frederick A ^a   Leeuwenburgh, Christiaan ^a   Baker, Henry V ^a   Moldawer, Lyle L ^a   Efron, Philip A ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Blunt trauma; microarray; mouse model; shock

Indexed keywords

TRANSCRIPTOME;

ADAPTIVE IMMUNITY; ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION PROFILING; GENOME ANALYSIS; HUMAN; HUMAN CELL; INFLAMMATION; INJURY; INJURY SCALE; INJURY SEVERITY; INNATE IMMUNITY; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; MOUSE; MULTIGENE FAMILY; MULTIPLE TRAUMA; NEUTROPHIL; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; SHOCK; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; ANIMALS; CASE-CONTROL STUDIES; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INJURY SEVERITY SCORE; LEUKOCYTES; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; NEUTROPHILS; RETROSPECTIVE STUDIES; TRANSCRIPTOME; TRAUMA CENTERS; WOUNDS, NONPENETRATING;

EID: 84901494412     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000000222     Document Type: Article

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