-
1
-
-
0026724481
-
The ACCP-SCCM consensus conference on sepsis and organ failure
-
Bone RC, Sibbald WJ, Sprung CL. The ACCP-SCCM Consensus Conference on sepsis and organ failure. Chest 1992; 101:1481-1483.
-
(1992)
Chest
, vol.101
, pp. 1481-1483
-
-
Bone, R.C.1
Sibbald, W.J.2
Sprung, C.L.3
-
3
-
-
84857090358
-
Sepsis, systemic inflammatory response, and multiple organ dysfunction: The mystery continues
-
Fry DE. Sepsis, systemic inflammatory response, and multiple organ dysfunction: The mystery continues. Am Surg 2012;78:1-8.
-
(2012)
Am Surg
, vol.78
, pp. 1-8
-
-
Fry, D.E.1
-
4
-
-
0023491364
-
Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia
-
DOI 10.1038/330662a0
-
Tracey KJ, Fong Y, Hesse DG, et al. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature 1987;330:662-664. (Pubitemid 18005583)
-
(1987)
Nature
, vol.330
, Issue.6149
, pp. 662-664
-
-
Tracey, K.J.1
Fong, Y.2
Hesse, D.G.3
Manogue, K.R.4
Lee, A.T.5
Kuo, G.C.6
Lowry, S.F.7
Cerami, A.8
-
5
-
-
0026772736
-
Interleukin-1 receptor blockade improves survival and hemodynamic performance in Escherichia coli septic shock, but fails to alter host responses to sublethal endotoxemia
-
Fischer E, Marano MA, Van Zee KJ, et al. Interleukin-1 receptor blockade improves survival and hemodynamic performance in Escherichia coli septic shock, but fails to alter host responses to sublethal endotoxemia. J Clin Invest 1992;89: 1551-1557.
-
(1992)
J Clin Invest
, vol.89
, pp. 1551-1557
-
-
Fischer, E.1
Marano, M.A.2
Van Zee, K.J.3
-
6
-
-
81855185336
-
Advances in the management of sepsis and the understanding of key immunologic defects
-
Skrupky LP, Kerby PW, Hotchkiss RS. Advances in the management of sepsis and the understanding of key immunologic defects. Anesthesiology 2011;115:1349-1362.
-
(2011)
Anesthesiology
, vol.115
, pp. 1349-1362
-
-
Skrupky, L.P.1
Kerby, P.W.2
Hotchkiss, R.S.3
-
7
-
-
0025354406
-
Laboratory models of sepsis and septic shock
-
DOI 10.1016/0022-4804(90)90260-9
-
Fink MP, Heard SO. Laboratory models of sepsis and septic shock. J Surg Res 1990;49:186-196. (Pubitemid 20241651)
-
(1990)
Journal of Surgical Research
, vol.49
, Issue.2
, pp. 186-196
-
-
Fink, M.P.1
Heard, S.O.2
-
8
-
-
0031606321
-
Animal models of sepsis and shock: A review and lessons learned
-
Deitch EA. Animal models of sepsis and shock: A review and lessons learned. Shock 1998;9:1-11. (Pubitemid 128463868)
-
(1998)
Shock
, vol.9
, Issue.1
, pp. 1-11
-
-
Deitch, E.A.1
-
9
-
-
0036948953
-
Animal and human models for sepsis
-
Schultz MJ, van der Poll T. Animal and human models for sepsis. Ann Med 2002;34:573-581. (Pubitemid 36113816)
-
(2002)
Annals of Medicine
, vol.34
, Issue.7-8
, pp. 573-581
-
-
Schultz, M.J.1
Van Der Poll, T.2
-
10
-
-
27644577000
-
Model organisms: Animal models of sepsis: Setting the stage
-
DOI 10.1038/nrd1854, PII N1854
-
Buras JA, Holzmann B, Sitkovsky M. Animal models of sepsis: Setting the stage. Nat Rev Drug Discov 2005;4: 854-865. (Pubitemid 41553966)
-
(2005)
Nature Reviews Drug Discovery
, vol.4
, Issue.10
, pp. 854-865
-
-
Buras, J.A.1
Holzmann, B.2
Sitkovsky, M.3
-
12
-
-
58849093274
-
Animal models of sepsis: Why does preclinical efficacy fail to translate to the clinical setting?
-
Dyson A, Singer M. Animal models of sepsis: Why does preclinical efficacy fail to translate to the clinical setting? Crit Care Med 2009;37(Suppl 1):S30-S37.
-
(2009)
Crit Care Med
, vol.37
, Issue.SUPPL. 1
-
-
Dyson, A.1
Singer, M.2
-
14
-
-
0032754358
-
Relationship between plasma levels of lipopolysaccharide (LPS) and LPS- binding protein in patients with severe sepsis and septic shock
-
DOI 10.1086/315093
-
Opal SM, Scannon PJ, Vincent JL, et al. Relationship between plasma levels of lipopolysaccharide (LPS) and LPS-binding protein in patients with severe sepsis and septic shock. J Infect Dis 1999;180:1584-1589. (Pubitemid 29506461)
-
(1999)
Journal of Infectious Diseases
, vol.180
, Issue.5
, pp. 1584-1589
-
-
Opal, S.M.1
Scannon, P.J.2
Vincent, J.-L.3
White, M.4
Carroll, S.F.5
Palardy, J.E.6
Parejo, N.A.7
Pribble, J.P.8
Lemke, J.H.9
-
15
-
-
3042785468
-
Diagnostic and prognostic implications of endotoxemia in critical illness: Results of the MEDIC study
-
DOI 10.1086/422254
-
Marshall JC, Foster D, Vincent JL, et al. Diagnostic and prognostic implications of endotoxemia in critical illness: Results of the MEDIC study. J Infect Dis 2004;190:527-534. (Pubitemid 38982092)
-
(2004)
Journal of Infectious Diseases
, vol.190
, Issue.3
, pp. 527-534
-
-
Marshall, J.C.1
Foster, D.2
Vincent, J.-L.3
Cook, D.J.4
Cohen, J.5
Dellinger, R.P.6
Opal, S.7
Abraham, E.8
Brett, S.J.9
Smith, T.10
Mehta, S.11
Derzko, A.12
Romaschin, A.13
-
16
-
-
33646786804
-
Neutralization of tumor necrosis factor in preclinical models of sepsis
-
Lorente JA, Marshall JC. Neutralization of tumor necrosis factor in preclinical models of sepsis. Shock 2005;24(Suppl 1):S107-S119.
-
(2005)
Shock
, vol.24
, Issue.SUPPL. 1
-
-
Lorente, J.A.1
Marshall, J.C.2
-
17
-
-
0035677992
-
Human models of innate immunity: Local and systemic inflammatory responses
-
DOI 10.1179/096805101101532963
-
Fiuza C, Suffredini AF. Human models of innate immunity: Local and systemic inflammatory responses. J Endotoxin Res 2001;7:385-388. (Pubitemid 34048540)
-
(2001)
Journal of Endotoxin Research
, vol.7
, Issue.5
, pp. 385-388
-
-
Fiuza, C.1
Suffredini, A.F.2
-
18
-
-
33646817775
-
Human endotoxemia: A model for mechanistic insight and therapeutic targeting
-
Lowry SF. Human endotoxemia: A model for mechanistic insight and therapeutic targeting. Shock 2005;24(Suppl 1):S94-S100.
-
(2005)
Shock
, vol.24
, Issue.SUPPL. 1
-
-
Lowry, S.F.1
-
20
-
-
0034923010
-
Staging of the pathophysiologic responses of the primate microvasculature to Escherichia coli and endotoxin: Examination of the elements of the compensated response and their links to the corresponding uncompensated lethal variants
-
Taylor FB Jr. Staging of the pathophysiologic responses of the primate microvasculature to Escherichia coli and endotoxin: Examination of the elements of the compensated response and their links to the corresponding uncompensated lethal variants. Crit Care Med 2001;29(Suppl 7):S78-S89.
-
(2001)
Crit Care Med
, vol.29
, Issue.SUPPL. 7
-
-
Taylor Jr., F.B.1
-
21
-
-
0035495804
-
Immunotherapy of sepsis
-
DOI 10.1016/S1473-3099(01)00093-7, PII S1473309901000937
-
van der Poll T. Immunotherapy of sepsis. Lancet Infect Dis 2001;1:165-174. (Pubitemid 33586050)
-
(2001)
Lancet Infectious Diseases
, vol.1
, Issue.3
, pp. 165-174
-
-
Van Der Poll, T.1
-
22
-
-
74949117097
-
Inflammation and coagulation
-
Levi M, van der Poll T. Inflammation and coagulation. Crit Care Med 2010;38(Suppl 2):S26-S34.
-
(2010)
Crit Care Med
, vol.38
, Issue.SUPPL. 2
-
-
Levi, M.1
Van Der Poll, T.2
-
23
-
-
0023757465
-
Antithrombin-III prevents the lethal effects of Escherichia coli infusion in baboons
-
Taylor FB Jr, Emerson TE Jr, Jordan R, et al. Antithrombin-III prevents the lethal effects of Escherichia coli infusion in baboons. Circ Shock 1988;26:227-235. (Pubitemid 18268347)
-
(1988)
Circulatory Shock
, vol.26
, Issue.3
, pp. 227-235
-
-
Taylor Jr., F.B.1
Emerson Jr., T.E.2
Jordan, R.3
Chang, A.K.4
Blick, K.E.5
-
24
-
-
0023122016
-
Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon
-
Taylor FB Jr, Chang A, Esmon CT, et al. Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon. J Clin Invest 1987;79:918-925. (Pubitemid 17050920)
-
(1987)
Journal of Clinical Investigation
, vol.79
, Issue.3
, pp. 918-925
-
-
Taylor Jr., F.B.1
Chang, A.2
Esmon, C.T.3
-
25
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
DOI 10.1056/NEJM200103083441001
-
Bernard GR, Vincent JL, Laterre PF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001;344:699-709. (Pubitemid 32204987)
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.10
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.-L.2
Laterre, P.-F.3
LaRosa, S.P.4
Dhainaut, J.-F.5
Lopez-Rodriguez, A.6
Steingrub, J.S.7
Garber, G.E.8
Helterbrand, J.D.9
Ely, E.W.10
Fisher, C.J.11
-
26
-
-
84856559847
-
Drotrecogin alfa (activated).A sad final fizzle to a roller-coaster party
-
Angus DC. Drotrecogin alfa (activated).A sad final fizzle to a roller-coaster party. Crit Care 2012;16:107.
-
(2012)
Crit Care
, vol.16
, pp. 107
-
-
Angus, D.C.1
-
27
-
-
84861665800
-
Drotrecogin alfa (activated) in adults with septic shock
-
Ranieri VM, Thompson BT, Barie PS, et al. Drotrecogin alfa (activated) in adults with septic shock. N Engl J Med 2012; 366:2055-2064.
-
(2012)
N Engl J Med
, vol.366
, pp. 2055-2064
-
-
Ranieri, V.M.1
Thompson, B.T.2
Barie, P.S.3
-
28
-
-
31344461826
-
Sepsis in European intensive care units: Results of the SOAP study
-
DOI 10.1097/01.CCM.0000194725.48928.3A
-
Vincent JL, Sakr Y, Sprung CL, et al. Sepsis in European intensive care units: Results of the SOAP study. Crit Care Med 2006;34:344-353. (Pubitemid 43145611)
-
(2006)
Critical Care Medicine
, vol.34
, Issue.2
, pp. 344-353
-
-
Vincent, J.-L.1
Sakr, Y.2
Sprung, C.L.3
Ranieri, V.M.4
Reinhart, K.5
Gerlach, H.6
Moreno, R.7
Carlet, J.8
Le Gall, J.-R.9
Payen, D.10
-
29
-
-
77953079396
-
Update in community-acquired and nosocomial pneumonia 2009
-
Torres A, Rello J. Update in community-acquired and nosocomial pneumonia 2009. Am J Respir Crit Care Med 2010; 181:782-787.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 782-787
-
-
Torres, A.1
Rello, J.2
-
30
-
-
33646795338
-
Pneumonia models and innate immunity to respiratory bacterial pathogens
-
Knapp S, Schultz MJ, van der Poll T. Pneumonia models and innate immunity to respiratory bacterial pathogens. Shock 2005;24(Suppl 1):S12-S18.
-
(2005)
Shock
, vol.24
, Issue.SUPPL. 1
-
-
Knapp, S.1
Schultz, M.J.2
Van Der Poll, T.3
-
31
-
-
0032933560
-
IL-10 is a major mediator of sepsis-induced impairment in lung antibacterial host defense
-
Steinhauser ML, Hogaboam CM, Kunkel SL, et al. IL-10 is a major mediator of sepsis-induced impairment in lung antibacterial host defense. J Immunol 1999;162:392-399. (Pubitemid 29018946)
-
(1999)
Journal of Immunology
, vol.162
, Issue.1
, pp. 392-399
-
-
Steinhauser, M.L.1
Hogaboam, C.M.2
Kunkel, S.L.3
Lukacs, N.W.4
Strieter, R.M.5
Standiford, T.J.6
-
32
-
-
33748317968
-
Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M
-
DOI 10.1172/JCI28054
-
Deng JC, Cheng G, Newstead MW, et al. Sepsis-induced suppression of lung innate immunity is mediated by IRAKM. J Clin Invest 2006;116:2532-2542. (Pubitemid 44330152)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.9
, pp. 2532-2542
-
-
Deng, J.C.1
Cheng, G.2
Newstead, M.W.3
Zeng, X.4
Kobayashi, K.5
Flavell, R.A.6
Standiford, T.J.7
-
33
-
-
0042886941
-
Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell Type 1-like immunostimulation
-
DOI 10.1084/jem.20021098
-
Prass K, Meisel C, Hoflich C, et al. Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation. J Exp Med 2003;198:725-736. (Pubitemid 37087772)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.5
, pp. 725-736
-
-
Prass, K.1
Meisel, C.2
Hoflich, C.3
Braun, J.4
Halle, E.5
Wolf, T.6
Ruscher, K.7
Victorov, I.V.8
Priller, J.9
Dirnagl, U.10
Volk, H.-D.11
Meisel, A.12
-
34
-
-
38549154462
-
Acute phase response impairs host defense against Pseudomonas aeruginosa pneumonia in mice
-
DOI 10.1097/01.CCM.0B013E3181620652, PII 0000324620080200000030
-
Renckens R, van Westerloo DJ, Roelofs JJ, et al. Acute phase response impairs host defense against Pseudomonas aeruginosa pneumonia in mice. Crit Care Med 2008;36:580-587. (Pubitemid 351158636)
-
(2008)
Critical Care Medicine
, vol.36
, Issue.2
, pp. 580-587
-
-
Renckens, R.1
Van Westerloo, D.J.2
Roelofs, J.J.T.H.3
Pater, J.M.4
Schultz, M.J.5
Florquin, S.6
Van Der Poll, T.7
-
35
-
-
5644233698
-
Acute pancreatitis in mice impairs bacterial clearance from the lungs, whereas concurrent pneumonia prolongs the course of pancreatitis
-
DOI 10.1097/01.CCM.0000142658.22254.74
-
van Westerloo DJ, Schultz MJ, Bruno MJ, et al. Acute pancreatitis in mice impairs bacterial clearance from the lungs, whereas concurrent pneumonia prolongs the course of pancreatitis. Crit Care Med 2004;32:1997-2001. (Pubitemid 39372531)
-
(2004)
Critical Care Medicine
, vol.32
, Issue.10
, pp. 1997-2001
-
-
Van Westerloo, D.J.1
Schultz, M.J.2
Bruno, M.J.3
De Vos, A.F.4
Florquin, S.5
Van Der Poll, T.6
-
36
-
-
16644385124
-
Cecal ligation and puncture versus colon ascendens stent peritonitis: Two distinct animal models for polymicrobial sepsis
-
Maier S, Traeger T, Entleutner M, et al. Cecal ligation and puncture versus colon ascendens stent peritonitis: Two distinct animal models for polymicrobial sepsis. Shock 2004; 21:505-511.
-
(2004)
Shock
, vol.21
, pp. 505-511
-
-
Maier, S.1
Traeger, T.2
Entleutner, M.3
-
37
-
-
0035152225
-
Experimental models of gramnegative sepsis
-
Parker SJ, Watkins PE. Experimental models of gramnegative sepsis. Br J Surg 2001;88:22-30.
-
(2001)
Br J Surg
, vol.88
, pp. 22-30
-
-
Parker, S.J.1
Watkins, P.E.2
-
38
-
-
79953292076
-
Cecal ligation and puncture: The gold standard model for polymicrobial sepsis?
-
Dejager L, Pinheiro I, Dejonckheere E, Libert C. Cecal ligation and puncture: The gold standard model for polymicrobial sepsis? Trends Microbiol 2011;19:198-208.
-
(2011)
Trends Microbiol
, vol.19
, pp. 198-208
-
-
Dejager, L.1
Pinheiro, I.2
Dejonckheere, E.3
Libert, C.4
-
39
-
-
77953082550
-
Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis
-
van Zoelen MA, Achouiti A, Schmidt AM, et al. Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis. Crit Care Med 2010;38: 1414-1422.
-
(2010)
Crit Care Med
, vol.38
, pp. 1414-1422
-
-
Van Zoelen, M.A.1
Achouiti, A.2
Schmidt, A.M.3
-
40
-
-
0033935120
-
An improved clinically relevant sepsis model in the conscious rat
-
Mathiak G, Szewczyk D, Abdullah F, et al. An improved clinically relevant sepsis model in the conscious rat. Crit Care Med 2000;28:1947-1952. (Pubitemid 30428756)
-
(2000)
Critical Care Medicine
, vol.28
, Issue.6
, pp. 1947-1952
-
-
Mathiak, G.1
Szewczyk, D.2
Abdullah, F.3
Ovadia, P.4
Feuerstein, G.5
Rabinovici, R.6
-
41
-
-
33646788082
-
Porcine models of severe sepsis: Emphasis on porcine peritonitis
-
Goldfarb RD, Dellinger RP, Parrillo JE. Porcine models of severe sepsis: Emphasis on porcine peritonitis. Shock 2005;24(Suppl 1):S75-S81.
-
(2005)
Shock
, vol.24
, Issue.SUPPL. 1
-
-
Goldfarb, R.D.1
Dellinger, R.P.2
Parrillo, J.E.3
-
42
-
-
0035500644
-
TNF-α compensates for the impaired host defense of IL-1 type I receptor-deficient mice during pneumococcal pneumonia
-
Rijneveld AW, Florquin S, Branger J, et al. TNF-alpha compensates for the impaired host defense of IL-1 type I receptor-deficient mice during pneumococcal pneumonia. J Immunol 2001;167:5240-5246. (Pubitemid 33009761)
-
(2001)
Journal of Immunology
, vol.167
, Issue.9
, pp. 5240-5246
-
-
Rijneveld, A.W.1
Florquin, S.2
Branger, J.3
Speelman, P.4
Van Deventer, S.J.H.5
Van Der Poll, T.6
-
43
-
-
0027478367
-
Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia
-
Gerard C, Bruyns C,Marchant A, et al. Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia. J Exp Med 1993;177:547-550. (Pubitemid 23117107)
-
(1993)
Journal of Experimental Medicine
, vol.177
, Issue.2
, pp. 547-550
-
-
Gerard, C.1
Bruyns, C.2
Marchant, A.3
Abramowicz, D.4
Vandenabeele, P.5
Delvaux, A.6
Fiers, W.7
Goldman, M.8
Velu, T.9
-
44
-
-
0029958178
-
Interleukin-10 impairs host defense in murine pneumococcal pneumonia
-
van der Poll T, Marchant A, Keogh CV, et al. Interleukin-10 impairs host defense in murine pneumococcal pneumonia. J Infect Dis 1996;174:994-1000. (Pubitemid 26357461)
-
(1996)
Journal of Infectious Diseases
, vol.174
, Issue.5
, pp. 994-1000
-
-
Van Der Poll, T.1
Marchant, A.2
Keogh, C.V.3
Goldman, M.4
Lowry, S.F.5
-
45
-
-
40649102666
-
Recombinant human activated protein C: Current insights into its mechanism of action
-
Levi M, van der Poll T. Recombinant human activated protein C: Current insights into its mechanism of action. Crit Care 2007;11(Suppl 5):S3.
-
(2007)
Crit Care
, vol.11
, Issue.SUPPL. 5
-
-
Levi, M.1
Van Der Poll, T.2
-
46
-
-
0141567620
-
Recombinant human activated protein C (rhAPC; drotrecogin alfa [activated]) has minimal effect on markers of coagulation, fibrinolysis, and inflammation in acute human endotoxemia
-
DOI 10.1182/blood-2003-02-0416
-
Derhaschnig U, Reiter R, Knobl P, et al. Recombinant human activated protein C (rhAPC; drotrecogin alfa [activated]) has minimal effect on markers of coagulation, fibrinolysis, and inflammation in acute human endotoxemia. Blood 2003;102: 2093-2098. (Pubitemid 37122385)
-
(2003)
Blood
, vol.102
, Issue.6
, pp. 2093-2098
-
-
Derhaschnig, U.1
Reiter, R.2
Knobl, P.3
Baumgartner, M.4
Keen, P.5
Jilma, B.6
|