A detailed characterization of the dysfunctional immunity and abnormal myelopoiesis induced by severe shock and trauma in the aged

Journal of Immunology

Volumn 195, Issue 5, 2015, Pages 2396-2407

  Nacionales, Dina C ^a   Szpila, Benjamin ^a   Ungaro, Ricardo ^a   Lopez, M Cecilia ^b   Zhang, Jianyi ^a   Gentile, Lori F ^a   Cuenca, Angela L ^a   Vanzant, Erin ^a   Mathias, Brittany ^a   Jyot, Jeevan ^b   Westerveld, Donevan ^a   Bihorac, Azra ^b   Joseph, Anna ^b   Mohr, Alicia ^a   Duckworth, Lizette V ^b   Moore, Frederick A ^a   Baker, Henry V ^b   Leeuwenburgh, Christiaan ^b   Moldawer, Lyle L ^a   Brakenridge, Scott ^a   Efron, Philip A ^a   more..

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA6 INTEGRIN; CD74 ANTIGEN; CHEMOKINE RECEPTOR CCR9; COLONY STIMULATING FACTOR 1; CXCL13 CHEMOKINE; HAPTOGLOBIN; INTERLEUKIN 1; INTERLEUKIN 12; INTERLEUKIN 7; MATRIX METALLOPROTEINASE; RANTES; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TRANSCRIPTOME;

ADAPTIVE IMMUNITY; ADULT; AGE DISTRIBUTION; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BONE MARROW EXAMINATION; COHORT ANALYSIS; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; FEMALE; GENE EXPRESSION REGULATION; GERIATRIC PATIENT; HEMORRHAGIC SHOCK; HIGH RISK POPULATION; HUMAN; IMMUNE DYSREGULATION; IMMUNOREGULATION; INFECTION RISK; INJURY SEVERITY; INNATE IMMUNITY; LUNG INJURY; LUNG LAVAGE; LYMPHOCYTE ACTIVATION; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; MORTALITY; MOUSE; MYELOPOIESIS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; PSEUDOMONAS PNEUMONIA; PUP (RODENT); SECONDARY INFECTION; UPREGULATION; VENTILATOR ASSOCIATED PNEUMONIA; AGE; ANIMAL; BRONCHOALVEOLAR LAVAGE FLUID; C57BL MOUSE; CELL CULTURE; COMPLICATION; CYTOLOGY; DNA MICROARRAY; GENETICS; IMMUNITY; IMMUNOLOGY; INJURY; LEUKOCYTE; METABOLISM; MIDDLE AGED; PNEUMONIA, VENTILATOR-ASSOCIATED; PSEUDOMONAS INFECTION; SURVIVAL RATE;

ADULT; AGE FACTORS; AGED; AGING; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; COHORT STUDIES; FEMALE; HUMANS; IMMUNITY; LEUKOCYTES; MALE; MICE, INBRED C57BL; MIDDLE AGED; MYELOPOIESIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PNEUMONIA, VENTILATOR-ASSOCIATED; PSEUDOMONAS INFECTIONS; SHOCK, HEMORRHAGIC; SURVIVAL RATE; TRANSCRIPTOME; WOUNDS AND INJURIES;

EID: 84940118145     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500984     Document Type: Article

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