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Volumn 33, Issue 4, 2011, Pages 353-367

Contribution of the immune system to the chemotherapeutic response

Author keywords

Cancer chemotherapy 2; T lymphocytes 3; Tumor immunity 1

Indexed keywords

ANTINEOPLASTIC AGENT;

EID: 85027939228     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-011-0246-z     Document Type: Review
Times cited : (29)

References (137)
  • 1
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • PID: 10647931, COI: 1:CAS:528:DC%2BD3cXks1CktA%3D%3D
    • Hanahan D, Weinberg R (2000) The hallmarks of cancer. Cell 100:57–70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.2
  • 2
    • 33748987908 scopus 로고    scopus 로고
    • Cancer despite immunosurveillance: immunoselection and immunosubversion
    • PID: 16977338, COI: 1:CAS:528:DC%2BD28XhtVSgurnM
    • Zitvogel L, Tesniere A, Kroemer G (2006) Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat Rev Immunol 6:715–727
    • (2006) Nat Rev Immunol , vol.6 , pp. 715-727
    • Zitvogel, L.1    Tesniere, A.2    Kroemer, G.3
  • 3
    • 34248193253 scopus 로고    scopus 로고
    • Immune surveillance of tumors
    • PID: 17476343, COI: 1:CAS:528:DC%2BD2sXlt1Omtr0%3D
    • Swann J, Smyth M (2007) Immune surveillance of tumors. J Clin Invest 117:1137–1146
    • (2007) J Clin Invest , vol.117 , pp. 1137-1146
    • Swann, J.1    Smyth, M.2
  • 4
    • 0029925375 scopus 로고    scopus 로고
    • Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma
    • PID: 8608507, COI: 1:STN:280:DyaK287pslChtA%3D%3D
    • Clemente CG, Mihm MC Jr, Bufalino R, Zurrida S, Collini P, Cascinelli N (1996) Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma. Cancer 77:1303–1310
    • (1996) Cancer , vol.77 , pp. 1303-1310
    • Clemente, C.G.1    Mihm, M.C.2    Bufalino, R.3    Zurrida, S.4    Collini, P.5    Cascinelli, N.6
  • 7
    • 40949089575 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes and perforation in colon cancer predict positive response to 5-fluorouracil chemotherapy
    • PID: 18316563, COI: 1:CAS:528:DC%2BD1cXislSrsL8%3D
    • Morris M, Platell C, Iacopetta B (2008) Tumor-infiltrating lymphocytes and perforation in colon cancer predict positive response to 5-fluorouracil chemotherapy. Clin Cancer Res 14:1413–1417
    • (2008) Clin Cancer Res , vol.14 , pp. 1413-1417
    • Morris, M.1    Platell, C.2    Iacopetta, B.3
  • 8
    • 33846444354 scopus 로고    scopus 로고
    • High number of intraepithelial CD8+ tumor-infiltrating lymphocytes is associated with the absence of lymph node metastases in patients with large early-stage cervical cancer
    • PID: 17210718, COI: 1:CAS:528:DC%2BD2sXisFSqsg%3D%3D
    • Piersma S, Jordanova E, Poelgeest V, Mie K, Kmc VD, Hulst J, Drijfhout J, Melief C, Kenter G, Fleuren G, Offringa R, Van Der Burg SH (2007) High number of intraepithelial CD8+ tumor-infiltrating lymphocytes is associated with the absence of lymph node metastases in patients with large early-stage cervical cancer. Cancer Res 67:354–361
    • (2007) Cancer Res , vol.67 , pp. 354-361
    • Piersma, S.1    Jordanova, E.2    Poelgeest, V.3    Mie, K.4    Kmc, V.D.5    Hulst, J.6    Drijfhout, J.7    Melief, C.8    Kenter, G.9    Fleuren, G.10    Offringa, R.11    Van Der Burg, S.H.12
  • 9
    • 0030787373 scopus 로고    scopus 로고
    • Prognostic value of tumour-infiltrating lymphocytes (TILs) in colorectal cancer
    • Ropponen KM, Eskelinen MJ, Lipponen PK, Alhava E, Kosma VM (1997) Prognostic value of tumour-infiltrating lymphocytes (TILs) in colorectal cancer. J Pathol 182(3):318–324
    • (1997) J Pathol , vol.182 , Issue.3 , pp. 318-324
    • Ropponen, K.M.1    Eskelinen, M.J.2    Lipponen, P.K.3    Alhava, E.4    Kosma, V.M.5
  • 11
    • 0033504907 scopus 로고    scopus 로고
    • Innate immune induction of the adaptive immune response
    • PID: 11232318, COI: 1:CAS:528:DC%2BD3cXktVWhsb4%3D
    • Medzhitov R, Janeway CA Jr (1999) Innate immune induction of the adaptive immune response. Cold Spring Harb Symp Quant Biol 64:429–435
    • (1999) Cold Spring Harb Symp Quant Biol , vol.64 , pp. 429-435
    • Medzhitov, R.1    Janeway, C.A.2
  • 12
    • 53549123079 scopus 로고    scopus 로고
    • Immune-mediated dormancy: an equilibrium with cancer
    • PID: 18515327, COI: 1:CAS:528:DC%2BD1cXht1amsbvJ
    • Teng M, Swann J, Koebel C, Schreiber R, Smyth M (2008) Immune-mediated dormancy: an equilibrium with cancer. J Leukoc Biol 84:988–993
    • (2008) J Leukoc Biol , vol.84 , pp. 988-993
    • Teng, M.1    Swann, J.2    Koebel, C.3    Schreiber, R.4    Smyth, M.5
  • 13
    • 0027531749 scopus 로고
    • Analysis of T cell receptor variability in tumor-infiltrating lymphocytes from a human regressive melanoma. Evidence for in situ T cell clonal expansion
    • PID: 8450047, COI: 1:CAS:528:DyaK3sXitlaisLk%3D
    • Ferradini L, Mackensen A, Genevee C, Bosq J, Duvillard P, Avril M, Hercend T (1993) Analysis of T cell receptor variability in tumor-infiltrating lymphocytes from a human regressive melanoma. Evidence for in situ T cell clonal expansion. J Clin Invest 91:1183–1190
    • (1993) J Clin Invest , vol.91 , pp. 1183-1190
    • Ferradini, L.1    Mackensen, A.2    Genevee, C.3    Bosq, J.4    Duvillard, P.5    Avril, M.6    Hercend, T.7
  • 14
    • 0033029559 scopus 로고    scopus 로고
    • A natural cytotoxic T cell response in a spontaneously regressing human melanoma targets a neoantigen resulting from a somatic point mutation
    • PID: 10064075, COI: 1:CAS:528:DyaK1MXhsVamsrc%3D
    • Zorn E, Hercend T (1999) A natural cytotoxic T cell response in a spontaneously regressing human melanoma targets a neoantigen resulting from a somatic point mutation. Eur J Immunol 29:592–601
    • (1999) Eur J Immunol , vol.29 , pp. 592-601
    • Zorn, E.1    Hercend, T.2
  • 17
    • 38649133581 scopus 로고    scopus 로고
    • Prognostic significance of CD3+ tumor-infiltrating lymphocytes in ovarian carcinoma
    • PID: 18037158
    • Tomsová M, Melichar B, Sedláková I, Steiner I (2008) Prognostic significance of CD3+ tumor-infiltrating lymphocytes in ovarian carcinoma. Gynecol Oncol 108:415–420
    • (2008) Gynecol Oncol , vol.108 , pp. 415-420
    • Tomsová, M.1    Melichar, B.2    Sedláková, I.3    Steiner, I.4
  • 18
    • 33745083070 scopus 로고    scopus 로고
    • CD8+ T-cell memory in tumor immunology and immunotherapy
    • PID: 16824130, COI: 1:CAS:528:DC%2BD28Xot1Grsbw%3D
    • Klebanoff C, Gattinoni L, Restifo N (2006) CD8+ T-cell memory in tumor immunology and immunotherapy. Immunol Rev 211:214–224
    • (2006) Immunol Rev , vol.211 , pp. 214-224
    • Klebanoff, C.1    Gattinoni, L.2    Restifo, N.3
  • 19
    • 41149097574 scopus 로고    scopus 로고
    • Adoptive cell transfer: a clinical path to effective cancer immunotherapy
    • PID: 18354418, COI: 1:CAS:528:DC%2BD1cXjsFCmsLg%3D
    • Rosenberg S, Restifo N, Yang J, Morgan R, Dudley M (2008) Adoptive cell transfer: a clinical path to effective cancer immunotherapy. Nat Rev Cancer 8:299–308
    • (2008) Nat Rev Cancer , vol.8 , pp. 299-308
    • Rosenberg, S.1    Restifo, N.2    Yang, J.3    Morgan, R.4    Dudley, M.5
  • 20
    • 38549096234 scopus 로고    scopus 로고
    • Shaping and reshaping CD8+ T-cell memory
    • PID: 18219309, COI: 1:CAS:528:DC%2BD1cXhtVGis74%3D
    • Harty J, Badovinac V (2008) Shaping and reshaping CD8+ T-cell memory. Nat Rev Immunol 8:107–119
    • (2008) Nat Rev Immunol , vol.8 , pp. 107-119
    • Harty, J.1    Badovinac, V.2
  • 21
    • 43449101541 scopus 로고    scopus 로고
    • Dendritic cells: driving the differentiation programme of T cells in viral infections
    • PID: 18347609, COI: 1:CAS:528:DC%2BD1cXlsFCltL8%3D
    • Masson F, Mount A, Wilson N, Belz G (2008) Dendritic cells: driving the differentiation programme of T cells in viral infections. Immunol Cell Biol 86:333–342
    • (2008) Immunol Cell Biol , vol.86 , pp. 333-342
    • Masson, F.1    Mount, A.2    Wilson, N.3    Belz, G.4
  • 22
    • 0034097041 scopus 로고    scopus 로고
    • CD8+ T cell effector mechanisms in resistance to infection
    • PID: 10837060, COI: 1:CAS:528:DC%2BD3cXjs1Gmsb0%3D
    • Harty J, Tvinnereim A, White D (2000) CD8+ T cell effector mechanisms in resistance to infection. Annu Rev Immunol 18:275–308
    • (2000) Annu Rev Immunol , vol.18 , pp. 275-308
    • Harty, J.1    Tvinnereim, A.2    White, D.3
  • 23
    • 0032797272 scopus 로고    scopus 로고
    • Chemokines and cell migration in secondary lymphoid organs
    • PID: 10617422, COI: 1:CAS:528:DyaK1MXotFGlsLY%3D
    • Cyster J (1999) Chemokines and cell migration in secondary lymphoid organs. Science 286:2098–2102
    • (1999) Science , vol.286 , pp. 2098-2102
    • Cyster, J.1
  • 24
    • 0035425351 scopus 로고    scopus 로고
    • Antigen presentation to CD8+ T cells: cross-priming in infectious diseases
    • Den Haan JM, Bevan MJ (2001) Antigen presentation to CD8+ T cells: cross-priming in infectious diseases. Curr Opin Immunol 13:437–441
    • (2001) Curr Opin Immunol , vol.13 , pp. 437-441
    • Den Haan, J.M.1    Bevan, M.J.2
  • 25
    • 0033006011 scopus 로고    scopus 로고
    • Development and maturation of secondary lymphoid tissues
    • PID: 10358764, COI: 1:CAS:528:DyaK1MXjtVWgu7g%3D
    • Fu YX, Chaplin D (1999) Development and maturation of secondary lymphoid tissues. Annu Rev Immunol 17:399–433
    • (1999) Annu Rev Immunol , vol.17 , pp. 399-433
    • Fu, Y.X.1    Chaplin, D.2
  • 26
    • 47949091237 scopus 로고    scopus 로고
    • Defective MHC class II presentation by Dendritic Cells Limits CD4 T Cell Help for antitumor CD8 T cell responses
    • PID: 18566380, COI: 1:CAS:528:DC%2BD1cXnsVGjsL8%3D
    • Gerner M, Casey K, Mescher M (2008) Defective MHC class II presentation by Dendritic Cells Limits CD4 T Cell Help for antitumor CD8 T cell responses. J Immunol 181:155–164
    • (2008) J Immunol , vol.181 , pp. 155-164
    • Gerner, M.1    Casey, K.2    Mescher, M.3
  • 27
    • 0033563121 scopus 로고    scopus 로고
    • Tumor antigens are constitutively presented in the draining lymph nodes
    • PID: 10229818, COI: 1:CAS:528:DyaK1MXjt12ltLw%3D
    • Marzo A, Lake R, Lo D, Sherman L, Mcwilliam A, Nelson D, Robinson B, Scott B (1999) Tumor antigens are constitutively presented in the draining lymph nodes. J Immunol 162:5838–5845
    • (1999) J Immunol , vol.162 , pp. 5838-5845
    • Marzo, A.1    Lake, R.2    Lo, D.3    Sherman, L.4    Mcwilliam, A.5    Nelson, D.6    Robinson, B.7    Scott, B.8
  • 28
    • 0035340761 scopus 로고    scopus 로고
    • Tumor progression despite efficient tumor antigen cross-presentation and effective “arming” of tumor antigen-specific CTL
    • PID: 11313395, COI: 1:CAS:528:DC%2BD3MXjtFyrurw%3D
    • Nelson D, Mukherjee S, Bundell C, Fisher S, Van Hagen D, Robinson B (2001) Tumor progression despite efficient tumor antigen cross-presentation and effective “arming” of tumor antigen-specific CTL. J Immunol 166:5557–5566
    • (2001) J Immunol , vol.166 , pp. 5557-5566
    • Nelson, D.1    Mukherjee, S.2    Bundell, C.3    Fisher, S.4    Van Hagen, D.5    Robinson, B.6
  • 30
    • 33751503177 scopus 로고    scopus 로고
    • The generation and modulation of antigen-specific memory CD8 T cell responses
    • PID: 16684891, COI: 1:CAS:528:DC%2BD28XmvVGluro%3D
    • Jabbari A, Harty J (2006) The generation and modulation of antigen-specific memory CD8 T cell responses. J Leukoc Biol 80:16–23
    • (2006) J Leukoc Biol , vol.80 , pp. 16-23
    • Jabbari, A.1    Harty, J.2
  • 34
    • 0037025944 scopus 로고    scopus 로고
    • Uncoupling of proliferative potential and gain of effector function by CD8+ T Cells responding to self-antigens
    • PID: 12163561, COI: 1:CAS:528:DC%2BD38XmtVOhtLw%3D
    • Hernandez J, Aung S, Marquardt K, Sherman L (2002) Uncoupling of proliferative potential and gain of effector function by CD8+ T Cells responding to self-antigens. J Exp Med 196:323–333
    • (2002) J Exp Med , vol.196 , pp. 323-333
    • Hernandez, J.1    Aung, S.2    Marquardt, K.3    Sherman, L.4
  • 35
    • 15244355148 scopus 로고    scopus 로고
    • Peripheral tolerance of CD8 T lymphocytes
    • PID: 15780985, COI: 1:CAS:528:DC%2BD2MXjt1Ohsbw%3D
    • Redmond W, Sherman L (2005) Peripheral tolerance of CD8 T lymphocytes. Immunity 22:275–284
    • (2005) Immunity , vol.22 , pp. 275-284
    • Redmond, W.1    Sherman, L.2
  • 36
    • 0029163387 scopus 로고
    • CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
    • PID: 7621080, COI: 1:CAS:528:DyaK2MXntVeqsLg%3D
    • Boise Lh, Minn A, Noel P, June Ch, Accavitti M, Lindsten T, Thompson C (1995) CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity 3:87–98
    • (1995) Immunity , vol.3 , pp. 87-98
    • Boise, L.1    Minn, A.2    Noel, P.3    June, C.4    Accavitti, M.5    Lindsten, T.6    Thompson, C.7
  • 37
    • 51349123892 scopus 로고    scopus 로고
    • Cancer immunotherapy by dendritic cells
    • PID: 18799145, COI: 1:CAS:528:DC%2BD1cXhtF2jtLvF
    • Melief C (2008) Cancer immunotherapy by dendritic cells. Immunity 29:372–383
    • (2008) Immunity , vol.29 , pp. 372-383
    • Melief, C.1
  • 38
    • 33745632047 scopus 로고    scopus 로고
    • Tumor progression despite massive influx of activated CD8+ T cells in a patient with malignant melanoma ascites
    • PID: 16468035, COI: 1:CAS:528:DC%2BD28Xmtl2qurc%3D
    • Harlin H, Kuna T, Peterson A, Meng Y, Gajewski T (2006) Tumor progression despite massive influx of activated CD8+ T cells in a patient with malignant melanoma ascites. Cancer Immunol Immunother 55:1185–1197
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 1185-1197
    • Harlin, H.1    Kuna, T.2    Peterson, A.3    Meng, Y.4    Gajewski, T.5
  • 41
    • 0034283019 scopus 로고    scopus 로고
    • Natural T-cell response against MHC class I epitopes of epithelial cell adhesion molecule, her-2/neu, and carcinoembryonic antigen in patients with colorectal cancer
    • PID: 10987297, COI: 1:CAS:528:DC%2BD3cXmsFWhsL8%3D
    • Nagorsen D, Keilholz U, Rivoltini L, Schmittel A, Letsch A, Asemissen A, Berger G, Buhr H, Thiel E, Scheibenbogen C (2000) Natural T-cell response against MHC class I epitopes of epithelial cell adhesion molecule, her-2/neu, and carcinoembryonic antigen in patients with colorectal cancer. Cancer Res 60:4850–4854
    • (2000) Cancer Res , vol.60 , pp. 4850-4854
    • Nagorsen, D.1    Keilholz, U.2    Rivoltini, L.3    Schmittel, A.4    Letsch, A.5    Asemissen, A.6    Berger, G.7    Buhr, H.8    Thiel, E.9    Scheibenbogen, C.10
  • 42
    • 0037431561 scopus 로고    scopus 로고
    • Differences in T-cell immunity toward tumor-associated antigens in colorectal cancer and breast cancer patients
    • PID: 12673683, COI: 1:CAS:528:DC%2BD3sXjt12mtrY%3D
    • Nagorsen D, Scheibenbogen C, Schaller G, Leigh B, Schmittel A, Letsch A, Thiel E, Keilholz U (2003) Differences in T-cell immunity toward tumor-associated antigens in colorectal cancer and breast cancer patients. Int J Cancer 105:221–225
    • (2003) Int J Cancer , vol.105 , pp. 221-225
    • Nagorsen, D.1    Scheibenbogen, C.2    Schaller, G.3    Leigh, B.4    Schmittel, A.5    Letsch, A.6    Thiel, E.7    Keilholz, U.8
  • 44
    • 0141891468 scopus 로고    scopus 로고
    • Evaluation of pre-existent immunity in patients with primary breast cancer: molecular and cellular assays to quantify antigen-specific T lymphocytes in peripheral blood mononuclear cells
    • PID: 14555509, COI: 1:CAS:528:DC%2BD3sXotVShsb8%3D
    • Rentzsch C, Kayser S, Stumm S, Watermann I, Walter S, Stevanovic S, Wallwiener D, Guckel B (2003) Evaluation of pre-existent immunity in patients with primary breast cancer: molecular and cellular assays to quantify antigen-specific T lymphocytes in peripheral blood mononuclear cells. Clin Cancer Res 9:4376–4386
    • (2003) Clin Cancer Res , vol.9 , pp. 4376-4386
    • Rentzsch, C.1    Kayser, S.2    Stumm, S.3    Watermann, I.4    Walter, S.5    Stevanovic, S.6    Wallwiener, D.7    Guckel, B.8
  • 45
    • 0037013829 scopus 로고    scopus 로고
    • CD8(+) T cell tolerance to a tumor-associated antigen is maintained at the level of expansion rather than effector function
    • PID: 12045239, COI: 1:CAS:528:DC%2BD38XktlGhsLw%3D
    • Ohlen C, Kalos M, Cheng L, Shur A, Hong D, Carson B, Kokot N, Lerner C, Sather B, Huseby E, Greenberg P (2002) CD8(+) T cell tolerance to a tumor-associated antigen is maintained at the level of expansion rather than effector function. J Exp Med 195:1407–1418
    • (2002) J Exp Med , vol.195 , pp. 1407-1418
    • Ohlen, C.1    Kalos, M.2    Cheng, L.3    Shur, A.4    Hong, D.5    Carson, B.6    Kokot, N.7    Lerner, C.8    Sather, B.9    Huseby, E.10    Greenberg, P.11
  • 46
    • 74949125667 scopus 로고    scopus 로고
    • BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination
    • PID: 20038811, COI: 1:CAS:528:DC%2BC3cXislWnuw%3D%3D
    • Derre L, Rivals J-P, Jandus C, Pastor S, Rimoldi D, Romero P, Michielin O, Olive D, Speiser D (2010) BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination. J Clin Invest 120:157–167
    • (2010) J Clin Invest , vol.120 , pp. 157-167
    • Derre, L.1    Rivals, J.-P.2    Jandus, C.3    Pastor, S.4    Rimoldi, D.5    Romero, P.6    Michielin, O.7    Olive, D.8    Speiser, D.9
  • 47
    • 77957723967 scopus 로고    scopus 로고
    • Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients
    • PID: 20819923, COI: 1:CAS:528:DC%2BC3cXht1Cms73N
    • Fourcade J, Sun Z, Benallaoua M, Guillaume P, Luescher I, Sander C, Kirkwood J, Kuchroo V, Zarour H (2010) Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients. J Exp Med 207:2175–2186
    • (2010) J Exp Med , vol.207 , pp. 2175-2186
    • Fourcade, J.1    Sun, Z.2    Benallaoua, M.3    Guillaume, P.4    Luescher, I.5    Sander, C.6    Kirkwood, J.7    Kuchroo, V.8    Zarour, H.9
  • 48
    • 77957744369 scopus 로고    scopus 로고
    • Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
    • PID: 20819927, COI: 1:CAS:528:DC%2BC3cXht1Cms73O
    • Sakuishi K, Apetoh L, Sullivan J, Blazar B, Kuchroo V, Anderson A (2010) Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. J Exp Med 207:2187–2194
    • (2010) J Exp Med , vol.207 , pp. 2187-2194
    • Sakuishi, K.1    Apetoh, L.2    Sullivan, J.3    Blazar, B.4    Kuchroo, V.5    Anderson, A.6
  • 49
    • 44349150012 scopus 로고    scopus 로고
    • Inhibitory B7-family molecules in the tumour microenvironment
    • PID: 18500231, COI: 1:CAS:528:DC%2BD1cXmt1Ojt74%3D
    • Zou W, Chen L (2008) Inhibitory B7-family molecules in the tumour microenvironment. Nat Rev Immunol 8:467–477
    • (2008) Nat Rev Immunol , vol.8 , pp. 467-477
    • Zou, W.1    Chen, L.2
  • 50
    • 0032211082 scopus 로고    scopus 로고
    • Defective function of Langerhans cells in tumor-bearing animals is the result of defective maturation from hemopoietic progenitors
    • PID: 9794417, COI: 1:CAS:528:DyaK1cXntVWgur8%3D
    • Ishida T, Oyama T, Carbone D, Gabrilovich D (1998) Defective function of Langerhans cells in tumor-bearing animals is the result of defective maturation from hemopoietic progenitors. J Immunol 161:4842–4851
    • (1998) J Immunol , vol.161 , pp. 4842-4851
    • Ishida, T.1    Oyama, T.2    Carbone, D.3    Gabrilovich, D.4
  • 51
    • 0032956922 scopus 로고    scopus 로고
    • Progressor but not regressor skin tumours inhibit Langerhans’ cell migration from epidermis to local lymph nodes
    • PID: 10447724, COI: 1:CAS:528:DyaK1MXjt12nu74%3D
    • Lucas H (1999) Progressor but not regressor skin tumours inhibit Langerhans’ cell migration from epidermis to local lymph nodes. Immunology 97:130–137
    • (1999) Immunology , vol.97 , pp. 130-137
    • Lucas, H.1
  • 52
    • 29644438266 scopus 로고    scopus 로고
    • Tumor-infiltrating dendritic cells are potent antigen-presenting cells able to activate T cells and mediate tumor rejection
    • PID: 16365396, COI: 1:CAS:528:DC%2BD2MXhtlagtLrK
    • Preynat-Seauve O, Schuler P, Contassot E, Beermann F, Huard B, French L (2006) Tumor-infiltrating dendritic cells are potent antigen-presenting cells able to activate T cells and mediate tumor rejection. J Immunol 176:61–67
    • (2006) J Immunol , vol.176 , pp. 61-67
    • Preynat-Seauve, O.1    Schuler, P.2    Contassot, E.3    Beermann, F.4    Huard, B.5    French, L.6
  • 54
    • 51349095960 scopus 로고    scopus 로고
    • Tuning microenvironments: induction of regulatory T cells by dendritic cells
    • PID: 18799144, COI: 1:CAS:528:DC%2BD1cXhtF2jtLvE
    • Belkaid Y, Oldenhove G (2008) Tuning microenvironments: induction of regulatory T cells by dendritic cells. Immunity 29:362–371
    • (2008) Immunity , vol.29 , pp. 362-371
    • Belkaid, Y.1    Oldenhove, G.2
  • 55
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • PID: 19197294, COI: 1:CAS:528:DC%2BD1MXhsFeqsbw%3D
    • Gabrilovich D, Nagaraj S (2009) Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 9:162–174
    • (2009) Nat Rev Immunol , vol.9 , pp. 162-174
    • Gabrilovich, D.1    Nagaraj, S.2
  • 56
    • 78049276260 scopus 로고    scopus 로고
    • Selective depletion of Foxp3+ regulatory T cells improves effective therapeutic vaccination against established melanoma
    • PID: 20924102, COI: 1:CAS:528:DC%2BC3cXht1yqs7jN
    • Klages K, Mayer C, Lahl K, Loddenkemper C, Teng M, Ngiow S, Smyth M, Hamann A, Huehn J, Sparwasser T (2010) Selective depletion of Foxp3+ regulatory T cells improves effective therapeutic vaccination against established melanoma. Cancer Res 70:7788–7799
    • (2010) Cancer Res , vol.70 , pp. 7788-7799
    • Klages, K.1    Mayer, C.2    Lahl, K.3    Loddenkemper, C.4    Teng, M.5    Ngiow, S.6    Smyth, M.7    Hamann, A.8    Huehn, J.9    Sparwasser, T.10
  • 57
    • 77956680680 scopus 로고    scopus 로고
    • A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers
    • PID: 20702612, COI: 1:CAS:528:DC%2BC3cXhtFGqs7bF
    • Kodumudi K, Woan K, Gilvary D, Sahakian E, Wei S, Djeu J (2010) A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers. Clin Cancer Res 16:4583–4594
    • (2010) Clin Cancer Res , vol.16 , pp. 4583-4594
    • Kodumudi, K.1    Woan, K.2    Gilvary, D.3    Sahakian, E.4    Wei, S.5    Djeu, J.6
  • 58
    • 78649557780 scopus 로고    scopus 로고
    • Efficient Treg depletion induces T-cell infiltration and rejection of large tumors
    • PID: 21072887, COI: 1:CAS:528:DC%2BC3cXhsVOktbnO
    • Li X, Kostareli E, Suffner J, Garbi N, Hämmerling G (2010) Efficient Treg depletion induces T-cell infiltration and rejection of large tumors. Eur J Immunol 40:3325–3335
    • (2010) Eur J Immunol , vol.40 , pp. 3325-3335
    • Li, X.1    Kostareli, E.2    Suffner, J.3    Garbi, N.4    Hämmerling, G.5
  • 59
    • 77951086882 scopus 로고    scopus 로고
    • Five-fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T Cell–dependent antitumor immunity
    • PID: 20388795, COI: 1:CAS:528:DC%2BC3cXkslShsLk%3D
    • Vincent J, Mignot GG, Chalmin F, Ladoire S, Bruchard ML, Chevriaux AL, Martin FO, Apetoh L, RéBé CD, Ghiringhelli FO (2010) Five-fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T Cell–dependent antitumor immunity. Cancer Res 70:3052–3061
    • (2010) Cancer Res , vol.70 , pp. 3052-3061
    • Vincent, J.1    Mignot, G.G.2    Chalmin, F.3    Ladoire, S.4    Bruchard, M.L.5    Chevriaux, A.L.6    Martin, F.O.7    Apetoh, L.8    RéBé, C.9    Ghiringhelli, F.O.10
  • 60
    • 50549088118 scopus 로고    scopus 로고
    • Immunogenic anti-cancer chemotherapy as an emerging concept
    • COI: 1:CAS:528:DC%2BD1cXhtVyltbfN
    • Haynes NM, Van Der Most RG, Lake RA, Smyth MJ (2008) Immunogenic anti-cancer chemotherapy as an emerging concept. Curr Op Immunol 20:545–557
    • (2008) Curr Op Immunol , vol.20 , pp. 545-557
    • Haynes, N.M.1    Van Der Most, R.G.2    Lake, R.A.3    Smyth, M.J.4
  • 62
    • 0038326676 scopus 로고    scopus 로고
    • Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, cross-priming rather than cross-tolerizing host tumor-specific CD8 T cells
    • PID: 12734333, COI: 1:CAS:528:DC%2BD3sXjsVGqsro%3D
    • Nowak A, Lake R, Marzo A, Scott B, Heath W, Collins E, Frelinger J, Robinson B (2003) Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, cross-priming rather than cross-tolerizing host tumor-specific CD8 T cells. J Immunol 170:4905–4913
    • (2003) J Immunol , vol.170 , pp. 4905-4913
    • Nowak, A.1    Lake, R.2    Marzo, A.3    Scott, B.4    Heath, W.5    Collins, E.6    Frelinger, J.7    Robinson, B.8
  • 63
    • 31544448260 scopus 로고    scopus 로고
    • Cranking the immunologic engine with chemotherapy: using context to drive tumor antigen cross-presentation towards useful antitumor immunity
    • PID: 16423984
    • Van Der Most RG, Currie A, Robinson BW, Lake RA (2006) Cranking the immunologic engine with chemotherapy: using context to drive tumor antigen cross-presentation towards useful antitumor immunity. Cancer Res 66:601–604
    • (2006) Cancer Res , vol.66 , pp. 601-604
    • Van Der Most, R.G.1    Currie, A.2    Robinson, B.W.3    Lake, R.A.4
  • 65
    • 37549032137 scopus 로고    scopus 로고
    • Immunological aspects of cancer chemotherapy
    • PID: 18097448, COI: 1:CAS:528:DC%2BD2sXhsVKrsLnP
    • Zitvogel L, Apetoh L, Ghiringhelli F, Kroemer G (2008) Immunological aspects of cancer chemotherapy. Nat Rev Immunol 8:59–73
    • (2008) Nat Rev Immunol , vol.8 , pp. 59-73
    • Zitvogel, L.1    Apetoh, L.2    Ghiringhelli, F.3    Kroemer, G.4
  • 67
    • 0014649984 scopus 로고
    • Modification of tumor regression by immunologic means
    • PID: 5387264, COI: 1:STN:280:DyaE3c3ptFWkug%3D%3D
    • Mihich E (1969) Modification of tumor regression by immunologic means. Cancer Res 29:2345–2350
    • (1969) Cancer Res , vol.29 , pp. 2345-2350
    • Mihich, E.1
  • 68
    • 0014492975 scopus 로고
    • Combined effects of chemotherapy and immunity against leukemia L1210 in DBA-2 mice
    • PID: 4887203, COI: 1:CAS:528:DyaF1MXpsVyluw%3D%3D
    • Mihich E (1969) Combined effects of chemotherapy and immunity against leukemia L1210 in DBA-2 mice. Cancer Res 29:848–854
    • (1969) Cancer Res , vol.29 , pp. 848-854
    • Mihich, E.1
  • 69
    • 0014067487 scopus 로고
    • Antitumor effects of kethoxal-bis(thiosemicarbazone) and 6-mercaptopurine in neonatally thymectomized mice
    • PID: 6023437, COI: 1:CAS:528:DyaF2sXhtVeqsr4%3D
    • Ferrer J, Mihich E (1967) Antitumor effects of kethoxal-bis(thiosemicarbazone) and 6-mercaptopurine in neonatally thymectomized mice. Proc Soc Exp Biol Med 124:939–944
    • (1967) Proc Soc Exp Biol Med , vol.124 , pp. 939-944
    • Ferrer, J.1    Mihich, E.2
  • 70
    • 0015846828 scopus 로고
    • Adriamycin and daunorubicin: a comparison of antitumor activities and tissue uptake in mice following immunosuppression
    • PID: 4720795, COI: 1:CAS:528:DyaE2cXit1eksg%3D%3D
    • Schwartz H, Grindey G (1973) Adriamycin and daunorubicin: a comparison of antitumor activities and tissue uptake in mice following immunosuppression. Cancer Res 33:1837–1844
    • (1973) Cancer Res , vol.33 , pp. 1837-1844
    • Schwartz, H.1    Grindey, G.2
  • 73
    • 67349133537 scopus 로고    scopus 로고
    • Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4 T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice
    • COI: 1:CAS:528:DC%2BD1MXms1Orsrk%3D
    • Le H, Graham L, Cha E, Morales J, Manjili Mh, Bear H (2009) Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4 T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice. Int Immunopharm 9:900–909
    • (2009) Int Immunopharm , vol.9 , pp. 900-909
    • Le, H.1    Graham, L.2    Cha, E.3    Morales, J.4    Manjili, M.5    Bear, H.6
  • 74
    • 38549148416 scopus 로고    scopus 로고
    • Gemcitabine has significant immunomodulatory activity in murine tumor models independent of its cytotoxic effects
    • PID: 17582217, COI: 1:CAS:528:DC%2BD2sXht1yktrnP
    • Suzuki E, Sun J, Kapoor V, Jassar A, Albelda S (2007) Gemcitabine has significant immunomodulatory activity in murine tumor models independent of its cytotoxic effects. Cancer Biol Ther 6:880–885
    • (2007) Cancer Biol Ther , vol.6 , pp. 880-885
    • Suzuki, E.1    Sun, J.2    Kapoor, V.3    Jassar, A.4    Albelda, S.5
  • 77
    • 34249650184 scopus 로고    scopus 로고
    • Bortezomib enhances dendritic cell (DC) mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications
    • PID: 17299090, COI: 1:CAS:528:DC%2BD2sXmt1Ogurk%3D
    • Spisek R, Charalambous A, Mazumder A, Vesole Dh, Jagannath S, Dhodapkar M (2007) Bortezomib enhances dendritic cell (DC) mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications. Blood 109:4839–4845
    • (2007) Blood , vol.109 , pp. 4839-4845
    • Spisek, R.1    Charalambous, A.2    Mazumder, A.3    Vesole, D.4    Jagannath, S.5    Dhodapkar, M.6
  • 81
    • 3442885649 scopus 로고    scopus 로고
    • Uric acid promotes tumor immune rejection
    • PID: 15289304, COI: 1:CAS:528:DC%2BD2cXmtF2mt74%3D
    • Hu D-E, Moore A, Thomsen L, Brindle K (2004) Uric acid promotes tumor immune rejection. Cancer Res 64:5059–5062
    • (2004) Cancer Res , vol.64 , pp. 5059-5062
    • Hu, D.-E.1    Moore, A.2    Thomsen, L.3    Brindle, K.4
  • 82
    • 0141998606 scopus 로고    scopus 로고
    • Molecular identification of a danger signal that alerts the immune system to dying cells
    • PID: 14520412, COI: 1:CAS:528:DC%2BD3sXnslSis7g%3D
    • Shi Y, Evans J, Rock K (2003) Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425:516–521
    • (2003) Nature , vol.425 , pp. 516-521
    • Shi, Y.1    Evans, J.2    Rock, K.3
  • 84
    • 70149089227 scopus 로고    scopus 로고
    • Classification of chemotherapeutic agents based on their differential in vitro effects on dendritic cells
    • PID: 19706756, COI: 1:CAS:528:DC%2BD1MXhtVOmtLrN
    • Tanaka H, Matsushima H, Mizumoto N, Takashima A (2009) Classification of chemotherapeutic agents based on their differential in vitro effects on dendritic cells. Cancer Res 69:6978–6986
    • (2009) Cancer Res , vol.69 , pp. 6978-6986
    • Tanaka, H.1    Matsushima, H.2    Mizumoto, N.3    Takashima, A.4
  • 85
    • 70149097098 scopus 로고    scopus 로고
    • Dual therapeutic efficacy of vinblastine as a unique chemotherapeutic agent capable of inducing dendritic cell maturation
    • PID: 19706755, COI: 1:CAS:528:DC%2BD1MXhtVOmtLrI
    • Tanaka H, Matsushima H, Nishibu A, Clausen B, Takashima A (2009) Dual therapeutic efficacy of vinblastine as a unique chemotherapeutic agent capable of inducing dendritic cell maturation. Cancer Res 69:6987–6994
    • (2009) Cancer Res , vol.69 , pp. 6987-6994
    • Tanaka, H.1    Matsushima, H.2    Nishibu, A.3    Clausen, B.4    Takashima, A.5
  • 86
    • 68349123372 scopus 로고    scopus 로고
    • Chemotherapeutic agents in noncytotoxic concentrations increase antigen presentation by Dendritic Cells via an IL-12-dependent mechanism
    • PID: 19535620, COI: 1:CAS:528:DC%2BD1MXnsVOrtb8%3D
    • Shurin G, Tourkova I, Kaneno R, Shurin M (2009) Chemotherapeutic agents in noncytotoxic concentrations increase antigen presentation by Dendritic Cells via an IL-12-dependent mechanism. J Immunol 183:137–144
    • (2009) J Immunol , vol.183 , pp. 137-144
    • Shurin, G.1    Tourkova, I.2    Kaneno, R.3    Shurin, M.4
  • 87
    • 68349083269 scopus 로고    scopus 로고
    • Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations
    • Kaneno R, Shurin G, Tourkova I, Shurin M (2009) Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations. J Trans Med 7:58
    • (2009) J Trans Med , vol.7 , pp. 58
    • Kaneno, R.1    Shurin, G.2    Tourkova, I.3    Shurin, M.4
  • 89
    • 70449474686 scopus 로고    scopus 로고
    • A distinct subset of self-renewing human memory CD8+ T cells survives cytotoxic chemotherapy
    • PID: 19879163, COI: 1:CAS:528:DC%2BD1MXhsFylsbjF
    • Turtle C, Swanson H, Fujii N, Estey Eh, Riddell S (2009) A distinct subset of self-renewing human memory CD8+ T cells survives cytotoxic chemotherapy. Immunity 31:834–844
    • (2009) Immunity , vol.31 , pp. 834-844
    • Turtle, C.1    Swanson, H.2    Fujii, N.3    Estey, E.4    Riddell, S.5
  • 90
    • 33947704281 scopus 로고    scopus 로고
    • Infiltration of a mesothelioma by IFN-gamma-producing cells and tumor rejection after depletion of regulatory T cells
    • PID: 17371963, COI: 1:CAS:528:DC%2BD2sXjt1WltLs%3D
    • Rudge G, Barrett SP, Scott B, Van Driel IR (2007) Infiltration of a mesothelioma by IFN-gamma-producing cells and tumor rejection after depletion of regulatory T cells. J Immunol 178:4089–4096
    • (2007) J Immunol , vol.178 , pp. 4089-4096
    • Rudge, G.1    Barrett, S.P.2    Scott, B.3    Van Driel, I.R.4
  • 91
    • 78049243425 scopus 로고    scopus 로고
    • Conditional regulatory T-cell depletion releases adaptive immunity preventing carcinogenesis and suppressing established tumor growth
    • PID: 20924111, COI: 1:CAS:528:DC%2BC3cXht1yqs7jO
    • Teng M, Ngiow S, Von Scheidt B, Mclaughlin N, Sparwasser T, Smyth M (2010) Conditional regulatory T-cell depletion releases adaptive immunity preventing carcinogenesis and suppressing established tumor growth. Cancer Res 70:7800–7809
    • (2010) Cancer Res , vol.70 , pp. 7800-7809
    • Teng, M.1    Ngiow, S.2    Von Scheidt, B.3    Mclaughlin, N.4    Sparwasser, T.5    Smyth, M.6
  • 92
    • 67349250111 scopus 로고    scopus 로고
    • Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cells: a role for cycling TNFR2-expressing effector-suppressor T cells in limiting effective chemotherapy
    • PID: 19052741
    • Van Der Most R, Currie A, Mahendran S, Prosser A, Darabi A, Robinson B, Nowak A, Lake R (2009) Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cells: a role for cycling TNFR2-expressing effector-suppressor T cells in limiting effective chemotherapy. Cancer Immunol Immunother 58:1219–1228
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1219-1228
    • Van Der Most, R.1    Currie, A.2    Mahendran, S.3    Prosser, A.4    Darabi, A.5    Robinson, B.6    Nowak, A.7    Lake, R.8
  • 93
    • 77955725489 scopus 로고    scopus 로고
    • Accumulation of foxp3+ T regulatory cells in draining lymph nodes correlates with disease progression and immune suppression in colorectal cancer patients
    • PID: 20682706, COI: 1:CAS:528:DC%2BC3cXhtVajs7zL
    • Deng L, Zhang H, Luan Y, Zhang J, Xing Q, Dong S, Wu X, Liu M, Wang S (2010) Accumulation of foxp3+ T regulatory cells in draining lymph nodes correlates with disease progression and immune suppression in colorectal cancer patients. Clin Cancer Res 16:4105–4112
    • (2010) Clin Cancer Res , vol.16 , pp. 4105-4112
    • Deng, L.1    Zhang, H.2    Luan, Y.3    Zhang, J.4    Xing, Q.5    Dong, S.6    Wu, X.7    Liu, M.8    Wang, S.9
  • 94
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
    • PID: 12193750, COI: 1:CAS:528:DC%2BD38XmsF2ns7k%3D
    • Liyanage U, Moore T, Joo H, Tanaka Y, Herrmann V, Doherty G, Drebin J, Strasberg S, Eberlein T, Goedegebuure P, Linehan D (2002) Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J Immunol 169:2756–2761
    • (2002) J Immunol , vol.169 , pp. 2756-2761
    • Liyanage, U.1    Moore, T.2    Joo, H.3    Tanaka, Y.4    Herrmann, V.5    Doherty, G.6    Drebin, J.7    Strasberg, S.8    Eberlein, T.9    Goedegebuure, P.10    Linehan, D.11
  • 95
    • 63249123219 scopus 로고    scopus 로고
    • CD4(+)CD25(+)CD127(low/-) regulatory T cells express Foxp3 and suppress effector T cell proliferation and contribute to gastric cancers progression
    • PID: 19153062, COI: 1:CAS:528:DC%2BD1MXktFWktbs%3D
    • Shen L, Wang J, Shen D, Yuan X, Dong P, Li M, Xue J, Zhang F, Ge H, Xu D (2009) CD4(+)CD25(+)CD127(low/-) regulatory T cells express Foxp3 and suppress effector T cell proliferation and contribute to gastric cancers progression. Clin Immunol 131:109–118
    • (2009) Clin Immunol , vol.131 , pp. 109-118
    • Shen, L.1    Wang, J.2    Shen, D.3    Yuan, X.4    Dong, P.5    Li, M.6    Xue, J.7    Zhang, F.8    Ge, H.9    Xu, D.10
  • 97
    • 77958118358 scopus 로고    scopus 로고
    • Molecular mechanisms of regulatory T cell development and suppressive function
    • PID: 20800825, COI: 1:CAS:528:DC%2BC3cXhsFGht77J
    • Kim J (2010) Molecular mechanisms of regulatory T cell development and suppressive function. Prog Mol Biol Transl Sci 92:279–314
    • (2010) Prog Mol Biol Transl Sci , vol.92 , pp. 279-314
    • Kim, J.1
  • 98
    • 1642378018 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative
    • PID: 14768038, COI: 1:CAS:528:DC%2BD2cXhsFals7k%3D
    • Ghiringhelli F, Larmonier N, Schmitt E, Parcellier A, Cathelin D, Garrido C, Chauffert B, Solary E, Bonnotte B, Martin F (2004) CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative. Eur J Immunol 34:336–344
    • (2004) Eur J Immunol , vol.34 , pp. 336-344
    • Ghiringhelli, F.1    Larmonier, N.2    Schmitt, E.3    Parcellier, A.4    Cathelin, D.5    Garrido, C.6    Chauffert, B.7    Solary, E.8    Bonnotte, B.9    Martin, F.10
  • 99
    • 33847368549 scopus 로고    scopus 로고
    • Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients
    • PID: 16960692, COI: 1:CAS:528:DC%2BD2sXisVaqtbY%3D
    • Ghiringhelli F, Menard C, Puig P, Ladoire S, Roux S, Martin F, Solary E, Le Cesne A, Zitvogel L, Chauffert B (2007) Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients. Cancer Immunol Immunother 56:641–648
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 641-648
    • Ghiringhelli, F.1    Menard, C.2    Puig, P.3    Ladoire, S.4    Roux, S.5    Martin, F.6    Solary, E.7    Le Cesne, A.8    Zitvogel, L.9    Chauffert, B.10
  • 100
    • 0034653477 scopus 로고    scopus 로고
    • Cyclophosphamide induces type I interferon and augments the number of CD44hi T lymphocytes in mice: implications for strategies of chemoimmunotherapy of cancer
    • PID: 10706870, COI: 1:CAS:528:DC%2BD3cXhvVGgsL0%3D
    • Schiavoni G, Mattei F, Di Pucchio T, Santini S, Bracci L, Belardelli F, Proietti E (2000) Cyclophosphamide induces type I interferon and augments the number of CD44hi T lymphocytes in mice: implications for strategies of chemoimmunotherapy of cancer. Blood 95:2024–2030
    • (2000) Blood , vol.95 , pp. 2024-2030
    • Schiavoni, G.1    Mattei, F.2    Di Pucchio, T.3    Santini, S.4    Bracci, L.5    Belardelli, F.6    Proietti, E.7
  • 101
    • 45549102822 scopus 로고    scopus 로고
    • Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor-infiltrating T regulatory cells
    • PID: 18453563, COI: 1:CAS:528:DC%2BD1cXltlCkt70%3D
    • Chen X, Subleski JJ, Kopf H, Howard OMZ, Mãnnel DN, Oppenheim JJ (2008) Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor-infiltrating T regulatory cells. J Immunol 180:6467–6471
    • (2008) J Immunol , vol.180 , pp. 6467-6471
    • Chen, X.1    Subleski, J.J.2    Kopf, H.3    Howard, O.M.Z.4    Mãnnel, D.N.5    Oppenheim, J.J.6
  • 102
    • 2942692037 scopus 로고    scopus 로고
    • CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion
    • PID: 15184501, COI: 1:CAS:528:DC%2BD2cXkvV2jsLY%3D
    • Herman A, Freeman G, Mathis D, Benoist C (2004) CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion. J Exp Med 199:1479–1489
    • (2004) J Exp Med , vol.199 , pp. 1479-1489
    • Herman, A.1    Freeman, G.2    Mathis, D.3    Benoist, C.4
  • 104
    • 70350108862 scopus 로고    scopus 로고
    • Cyclophosphamide resets dendritic cell homeostasis and enhances antitumor immunity through effects that extend beyond regulatory T cell elimination
    • PID: 19590872, COI: 1:CAS:528:DC%2BD1MXht1OnsL7L
    • Radojcic V, Bezak K, Skarica M, Pletneva M, Yoshimura K, Schulick R, Luznik L (2010) Cyclophosphamide resets dendritic cell homeostasis and enhances antitumor immunity through effects that extend beyond regulatory T cell elimination. Cancer Immunol Immunother 59:137–148
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 137-148
    • Radojcic, V.1    Bezak, K.2    Skarica, M.3    Pletneva, M.4    Yoshimura, K.5    Schulick, R.6    Luznik, L.7
  • 105
    • 15944410592 scopus 로고    scopus 로고
    • Inhibition of CD4 + 25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide
    • PID: 15591121, COI: 1:CAS:528:DC%2BD2MXivFGmtLw%3D
    • Lutsiak M, Semnani R, De Pascalis R, Kashmiri S, Schlom J, Sabzevari H (2005) Inhibition of CD4 + 25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide. Blood 105:2862–2868
    • (2005) Blood , vol.105 , pp. 2862-2868
    • Lutsiak, M.1    Semnani, R.2    De Pascalis, R.3    Kashmiri, S.4    Schlom, J.5    Sabzevari, H.6
  • 106
    • 20444467321 scopus 로고    scopus 로고
    • Immunostimulatory effects of low-dose cyclophosphamide are controlled by inducible nitric oxide synthase
    • PID: 15958544, COI: 1:CAS:528:DC%2BD2MXltFemtLk%3D
    • Loeffler M, KrãGer JRA, Reisfeld RA (2005) Immunostimulatory effects of low-dose cyclophosphamide are controlled by inducible nitric oxide synthase. Cancer Res 65:5027–5030
    • (2005) Cancer Res , vol.65 , pp. 5027-5030
    • Loeffler, M.1    KrãGer, J.R.A.2    Reisfeld, R.A.3
  • 107
    • 77953730756 scopus 로고    scopus 로고
    • Selective depletion of CD4+CD25 + Foxp3+ regulatory T cells by low-dose cyclophosphamide is explained by reduced intracellular ATP levels
    • PID: 20501849, COI: 1:CAS:528:DC%2BC3cXntlKltrc%3D
    • Zhao J, Cao Y, Lei Z, Yang Z, Zhang B, Huang B (2010) Selective depletion of CD4+CD25 + Foxp3+ regulatory T cells by low-dose cyclophosphamide is explained by reduced intracellular ATP levels. Cancer Res 70:4850–4858
    • (2010) Cancer Res , vol.70 , pp. 4850-4858
    • Zhao, J.1    Cao, Y.2    Lei, Z.3    Yang, Z.4    Zhang, B.5    Huang, B.6
  • 108
    • 0023930413 scopus 로고
    • Effect of low dose cyclophosphamide on the immune system of cancer patients: depletion of CD4+, 2 H4+ suppressor-inducer T-cells
    • PID: 2830969, COI: 1:STN:280:DyaL1c7ltVyitQ%3D%3D
    • Berd D, Mastrangelo M (1988) Effect of low dose cyclophosphamide on the immune system of cancer patients: depletion of CD4+, 2 H4+ suppressor-inducer T-cells. Cancer Res 48:1671–1675
    • (1988) Cancer Res , vol.48 , pp. 1671-1675
    • Berd, D.1    Mastrangelo, M.2
  • 109
    • 0025006629 scopus 로고
    • Suppressor cell activity in a randomized trial of patients receiving active specific immunotherapy with melanoma cell vaccine and low dosages of cyclophosphamide
    • PID: 2143687, COI: 1:STN:280:DyaK3czlt1Gktw%3D%3D
    • Hoon D, Foshag L, Nizze A, Bohman R, Morton D (1990) Suppressor cell activity in a randomized trial of patients receiving active specific immunotherapy with melanoma cell vaccine and low dosages of cyclophosphamide. Cancer Res 50:5358–5364
    • (1990) Cancer Res , vol.50 , pp. 5358-5364
    • Hoon, D.1    Foshag, L.2    Nizze, A.3    Bohman, R.4    Morton, D.5
  • 111
    • 0022597114 scopus 로고
    • Induction of Cell-mediated Immunity to Autologous Melanoma Cells and Regression of Metastases after Treatment with a Melanoma Cell Vaccine Preceded by Cyclophosphamide
    • PID: 3697996, COI: 1:STN:280:DyaL287ovFGkug%3D%3D
    • Berd D, Maguire H, Mastrangelo M (1986) Induction of Cell-mediated Immunity to Autologous Melanoma Cells and Regression of Metastases after Treatment with a Melanoma Cell Vaccine Preceded by Cyclophosphamide. Cancer Res 46:2572–2577
    • (1986) Cancer Res , vol.46 , pp. 2572-2577
    • Berd, D.1    Maguire, H.2    Mastrangelo, M.3
  • 112
    • 0029787977 scopus 로고    scopus 로고
    • Enhancing the effect of THERATOPE STn-KLH cancer vaccine in patients with metastatic breast cancer by pretreatment with low-dose intravenous cyclophosphamide
    • PID: 8877724, COI: 1:CAS:528:DyaK28XlvFOgtL0%3D
    • Maclean G, Miles D, Rubens R, Reddish M, Longenecker B (1996) Enhancing the effect of THERATOPE STn-KLH cancer vaccine in patients with metastatic breast cancer by pretreatment with low-dose intravenous cyclophosphamide. J Immunother Emphasis Tumor Immunol 19:309–316
    • (1996) J Immunother Emphasis Tumor Immunol , vol.19 , pp. 309-316
    • Maclean, G.1    Miles, D.2    Rubens, R.3    Reddish, M.4    Longenecker, B.5
  • 113
    • 77649148760 scopus 로고    scopus 로고
    • Low-dose cyclophosphamide treatment impairs regulatory T cells and unmasks AFP-specific CD4+ T-cell responses in patients with advanced HCC
    • PID: 20139774, COI: 1:CAS:528:DC%2BC3cXitlWisrk%3D
    • Greten T, Ormandy L, Fikuart A, Hochst B, Henschen S, Horning M, Manns M, Korangy F (2010) Low-dose cyclophosphamide treatment impairs regulatory T cells and unmasks AFP-specific CD4+ T-cell responses in patients with advanced HCC. J Immunother 33:211–218
    • (2010) J Immunother , vol.33 , pp. 211-218
    • Greten, T.1    Ormandy, L.2    Fikuart, A.3    Hochst, B.4    Henschen, S.5    Horning, M.6    Manns, M.7    Korangy, F.8
  • 114
    • 59449100645 scopus 로고    scopus 로고
    • Paclitaxel reduces regulatory T cell numbers and inhibitory function and enhances the anti-tumor effects of the TLR9 agonist PF-3512676 in the mouse
    • PID: 18802696, COI: 1:CAS:528:DC%2BD1MXht1Olsbk%3D
    • Vicari A, Luu R, Zhang N, Patel S, Makinen S, Hanson D, Weeratna R, Krieg A (2009) Paclitaxel reduces regulatory T cell numbers and inhibitory function and enhances the anti-tumor effects of the TLR9 agonist PF-3512676 in the mouse. Cancer Immunol Immunother 58:615–628
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 615-628
    • Vicari, A.1    Luu, R.2    Zhang, N.3    Patel, S.4    Makinen, S.5    Hanson, D.6    Weeratna, R.7    Krieg, A.8
  • 115
    • 54049093133 scopus 로고    scopus 로고
    • Differential impairment of regulatory T cells rather than effector T cells by paclitaxel-based chemotherapy
    • PID: 18771959, COI: 1:CAS:528:DC%2BD1cXht1Kgt7zE
    • Zhang L, Dermawan K, Jin M, Liu R, Zheng H, Xu L, Zhang Y, Cai Y, Chu Y, Xiong S (2008) Differential impairment of regulatory T cells rather than effector T cells by paclitaxel-based chemotherapy. Clin Immunol 129:219–229
    • (2008) Clin Immunol , vol.129 , pp. 219-229
    • Zhang, L.1    Dermawan, K.2    Jin, M.3    Liu, R.4    Zheng, H.5    Xu, L.6    Zhang, Y.7    Cai, Y.8    Chu, Y.9    Xiong, S.10
  • 116
    • 0035164478 scopus 로고    scopus 로고
    • Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer
    • PID: 11123353, COI: 1:CAS:528:DC%2BD3MXis1elsw%3D%3D
    • Almand B, Clark J, Nikitina E, Van Beynen J, English N, Knight S, Carbone D, Gabrilovich D (2001) Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J Immunol 166:678–689
    • (2001) J Immunol , vol.166 , pp. 678-689
    • Almand, B.1    Clark, J.2    Nikitina, E.3    Van Beynen, J.4    English, N.5    Knight, S.6    Carbone, D.7    Gabrilovich, D.8
  • 117
    • 54849440346 scopus 로고    scopus 로고
    • Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
    • PID: 18446337, COI: 1:CAS:528:DC%2BD1cXht1yqs7bN
    • Diaz-Montero C, Salem M, Nishimura M, Garrett-Mayer E, Cole D, Montero A (2009) Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol Immunother 58:49–59
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 49-59
    • Diaz-Montero, C.1    Salem, M.2    Nishimura, M.3    Garrett-Mayer, E.4    Cole, D.5    Montero, A.6
  • 118
    • 41149148269 scopus 로고    scopus 로고
    • Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives
    • PID: 18364002, COI: 1:CAS:528:DC%2BD1cXlsFejt78%3D
    • Rodriguez P, Ochoa A (2008) Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives. Immunol Rev 222:180–191
    • (2008) Immunol Rev , vol.222 , pp. 180-191
    • Rodriguez, P.1    Ochoa, A.2
  • 119
    • 75149123468 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine
    • PID: 20028852, COI: 1:CAS:528:DC%2BC3cXltVaj
    • Srivastava M, Sinha P, Clements V, Rodriguez P, Ostrand-Rosenberg S (2010) Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine. Cancer Res 70:68–77
    • (2010) Cancer Res , vol.70 , pp. 68-77
    • Srivastava, M.1    Sinha, P.2    Clements, V.3    Rodriguez, P.4    Ostrand-Rosenberg, S.5
  • 120
    • 75149179545 scopus 로고    scopus 로고
    • Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer
    • PID: 19996287, COI: 1:CAS:528:DC%2BC3cXltVan
    • Pan P, Ma G, Weber K, Ozao-Choy J, Wang G, Yin B, Divino C, Chen Sh (2010) Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer. Cancer Res 70:99–108
    • (2010) Cancer Res , vol.70 , pp. 99-108
    • Pan, P.1    Ma, G.2    Weber, K.3    Ozao-Choy, J.4    Wang, G.5    Yin, B.6    Divino, C.7    Chen, S.8
  • 121
    • 33746115391 scopus 로고    scopus 로고
    • CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1 + CD11b+ myeloid cells
    • PID: 16818658, COI: 1:CAS:528:DC%2BD28XmsVals7c%3D
    • Yang R, Cai Z, Zhang Y, Yutzy W, Roby K, Roden R (2006) CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1 + CD11b+ myeloid cells. Cancer Res 66:6807–6815
    • (2006) Cancer Res , vol.66 , pp. 6807-6815
    • Yang, R.1    Cai, Z.2    Zhang, Y.3    Yutzy, W.4    Roby, K.5    Roden, R.6
  • 122
    • 31544446571 scopus 로고    scopus 로고
    • Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • PID: 16424049, COI: 1:CAS:528:DC%2BD28XlsFOgug%3D%3D
    • Huang B, Pan P, Li Q, Sato A, Levy D, Bromberg J, Divino C, Chen Sh (2006) Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res 66:1123–1131
    • (2006) Cancer Res , vol.66 , pp. 1123-1131
    • Huang, B.1    Pan, P.2    Li, Q.3    Sato, A.4    Levy, D.5    Bromberg, J.6    Divino, C.7    Chen, S.8
  • 123
    • 78049479930 scopus 로고    scopus 로고
    • Chemotherapy delivered after viral immunogene therapy augments antitumor efficacy via multiple immune-mediated mechanisms
    • PID: 20683443, COI: 1:CAS:528:DC%2BC3cXpsF2rt7g%3D
    • Fridlender Z, Sun J, Singhal S, Kapoor V, Cheng G, Suzuki E, Albelda S (2010) Chemotherapy delivered after viral immunogene therapy augments antitumor efficacy via multiple immune-mediated mechanisms. Mol Ther 18:1947–1959
    • (2010) Mol Ther , vol.18 , pp. 1947-1959
    • Fridlender, Z.1    Sun, J.2    Singhal, S.3    Kapoor, V.4    Cheng, G.5    Suzuki, E.6    Albelda, S.7
  • 124
    • 34547630506 scopus 로고    scopus 로고
    • A Combination of Chemoimmunotherapies Can Efficiently Break Self-Tolerance and Induce Antitumor Immunity in a Tolerogenic Murine Tumor Model
    • PID: 17671218, COI: 1:CAS:528:DC%2BD2sXosVemtb8%3D
    • Ko H-J, Kim Y-J, Kim Y-S, Chang W-S, Ko S-Y, Chang S-Y, Sakaguchi S, Kang C-Y (2007) A Combination of Chemoimmunotherapies Can Efficiently Break Self-Tolerance and Induce Antitumor Immunity in a Tolerogenic Murine Tumor Model. Cancer Res 67:7477–7486
    • (2007) Cancer Res , vol.67 , pp. 7477-7486
    • Ko, H.-J.1    Kim, Y.-J.2    Kim, Y.-S.3    Chang, W.-S.4    Ko, S.-Y.5    Chang, S.-Y.6    Sakaguchi, S.7    Kang, C.-Y.8
  • 125
    • 34548805636 scopus 로고    scopus 로고
    • Cross-Talk between Myeloid-Derived Suppressor Cells and Macrophages Subverts Tumor Immunity toward a Type 2 Response
    • PID: 17617589, COI: 1:CAS:528:DC%2BD2sXnt1Wmtbs%3D
    • Sinha P, Clements V, Bunt S, Albelda S, Ostrand-Rosenberg S (2007) Cross-Talk between Myeloid-Derived Suppressor Cells and Macrophages Subverts Tumor Immunity toward a Type 2 Response. J Immunol 179:977–983
    • (2007) J Immunol , vol.179 , pp. 977-983
    • Sinha, P.1    Clements, V.2    Bunt, S.3    Albelda, S.4    Ostrand-Rosenberg, S.5
  • 126
    • 25144466458 scopus 로고    scopus 로고
    • Gemcitabine Selectively Eliminates Splenic Gr-1+/CD11b+ Myeloid Suppressor Cells in Tumor-Bearing Animals and Enhances Antitumor Immune Activity
    • PID: 16166452, COI: 1:CAS:528:DC%2BD2MXhtVShsb3O
    • Suzuki E, Kapoor V, Jassar A, Kaiser L, Albelda S (2005) Gemcitabine Selectively Eliminates Splenic Gr-1+/CD11b+ Myeloid Suppressor Cells in Tumor-Bearing Animals and Enhances Antitumor Immune Activity. Clin Cancer Res 11:6713–6721
    • (2005) Clin Cancer Res , vol.11 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.3    Kaiser, L.4    Albelda, S.5
  • 127
    • 0042591416 scopus 로고    scopus 로고
    • Synergy between Chemotherapy and Immunotherapy in the Treatment of Established Murine Solid Tumors
    • PID: 12907622, COI: 1:CAS:528:DC%2BD3sXmtFersrY%3D
    • Nowak A, Robinson B, Lake R (2003) Synergy between Chemotherapy and Immunotherapy in the Treatment of Established Murine Solid Tumors. Cancer Res 63:4490–4496
    • (2003) Cancer Res , vol.63 , pp. 4490-4496
    • Nowak, A.1    Robinson, B.2    Lake, R.3
  • 128
    • 22244489353 scopus 로고    scopus 로고
    • Effect of gemcitabine on immune cells in subjects with adenocarcinoma of the pancreas
    • PID: 15782312, COI: 1:CAS:528:DC%2BD2MXlvVyns7o%3D
    • Plate J, Plate A, Shott S, Bograd S, Harris J (2005) Effect of gemcitabine on immune cells in subjects with adenocarcinoma of the pancreas. Cancer Immunol Immunother 54:915–925
    • (2005) Cancer Immunol Immunother , vol.54 , pp. 915-925
    • Plate, J.1    Plate, A.2    Shott, S.3    Bograd, S.4    Harris, J.5
  • 132
    • 67649422143 scopus 로고    scopus 로고
    • Impact of surgery and chemotherapy on cellular immunity in pancreatic carcinoma patients in view of an integration of standard cancer treatment with immunotherapy
    • PID: 19424589, COI: 1:CAS:528:DC%2BD1MXmsVCiu74%3D
    • Bellone G, Novarino A, Vizio B, Brondino G, Addeo A, Prati A, Giacobino A, Campra D, Fronda G, Ciuffreda L (2009) Impact of surgery and chemotherapy on cellular immunity in pancreatic carcinoma patients in view of an integration of standard cancer treatment with immunotherapy. Int J Oncol 34:1701–1715
    • (2009) Int J Oncol , vol.34 , pp. 1701-1715
    • Bellone, G.1    Novarino, A.2    Vizio, B.3    Brondino, G.4    Addeo, A.5    Prati, A.6    Giacobino, A.7    Campra, D.8    Fronda, G.9    Ciuffreda, L.10
  • 133
    • 14844293666 scopus 로고    scopus 로고
    • Recovery of CD8+ T-cell function during systemic chemotherapy in advanced ovarian cancer
    • PID: 16061686, COI: 1:CAS:528:DC%2BD2MXmvFSlu7o%3D
    • Coleman S, Clayton A, Mason M, Jasani B, Adams M, Tabi Z (2005) Recovery of CD8+ T-cell function during systemic chemotherapy in advanced ovarian cancer. Cancer Res 65:7000–7006
    • (2005) Cancer Res , vol.65 , pp. 7000-7006
    • Coleman, S.1    Clayton, A.2    Mason, M.3    Jasani, B.4    Adams, M.5    Tabi, Z.6
  • 134
    • 67650034945 scopus 로고    scopus 로고
    • Effects of the conventional antitumor therapies surgery, chemotherapy, radiotherapy and immunotherapy on regulatory T lymphocytes in cancer patients
    • PID: 19443415, COI: 1:CAS:528:DC%2BD1MXos1Wnurw%3D
    • Lissoni P, Brivio F, Fumagalli L, Messina G, Meregalli S, Porro G, Rovelli F, Vigore L, Tisi E, D’amico G (2009) Effects of the conventional antitumor therapies surgery, chemotherapy, radiotherapy and immunotherapy on regulatory T lymphocytes in cancer patients. Anticancer Res 29:1847–1852
    • (2009) Anticancer Res , vol.29 , pp. 1847-1852
    • Lissoni, P.1    Brivio, F.2    Fumagalli, L.3    Messina, G.4    Meregalli, S.5    Porro, G.6    Rovelli, F.7    Vigore, L.8    Tisi, E.9    D’amico, G.10
  • 135
    • 71849088755 scopus 로고    scopus 로고
    • The immunologic aspects in advanced ovarian cancer patients treated with paclitaxel and carboplatin chemotherapy
    • PID: 19727719, COI: 1:CAS:528:DC%2BD1MXhsVajurvO
    • Wu X, Feng Q, Wang Y, Shi J, Ge H, Di W (2010) The immunologic aspects in advanced ovarian cancer patients treated with paclitaxel and carboplatin chemotherapy. Cancer Immunol Immunother 59:279–291
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 279-291
    • Wu, X.1    Feng, Q.2    Wang, Y.3    Shi, J.4    Ge, H.5    Di, W.6
  • 137
    • 77951258833 scopus 로고    scopus 로고
    • Features of responding T cells in cancer and chronic infection
    • PID: 20207527, COI: 1:CAS:528:DC%2BC3cXks1Srsbc%3D
    • Kim P, Ahmed R (2010) Features of responding T cells in cancer and chronic infection. Curr Opin Immunol 22:223–230
    • (2010) Curr Opin Immunol , vol.22 , pp. 223-230
    • Kim, P.1    Ahmed, R.2


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