A natural cytotoxic T cell response in a spontaneously regressing human melanoma targets a neoantigen resulting from a somatic point mutation

European Journal of Immunology

Volumn 29, Issue 2, 1999, Pages 592-601

  Zorn, Emmanuel ^a,b   Hercend, Thierry ^a,c  

^a HÔPITAL PAUL BROUSSE   (France)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c Vertex Pharmaceuticals Ltd   (United Kingdom)

Author keywords

Immunosurveillance; Mutated tumor antigen; Myosin class I; Regressive melanoma; Tumor infiltrating lymphocyte

Indexed keywords

CD8 ANTIGEN; MYOSIN; TUMOR ANTIGEN;

AGED; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CASE REPORT; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; FEMALE; GENE SEQUENCE; HUMAN; HUMAN CELL; LYMPHOCYTE CLONE; MELANOMA; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; SOMATIC MUTATION; TUMOR ASSOCIATED LEUKOCYTE;

AGED; AMINO ACID SEQUENCE; ANTIGENS, NEOPLASM; CYTOTOXICITY, IMMUNOLOGIC; DNA, COMPLEMENTARY; FEMALE; HUMANS; LYMPHOCYTES, TUMOR-INFILTRATING; MELANOMA; MOLECULAR SEQUENCE DATA; NEOPLASM REGRESSION, SPONTANEOUS; POINT MUTATION; SKIN NEOPLASMS; T-LYMPHOCYTES; TUMOR CELLS, CULTURED;

EID: 0033029559     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199902)29:02<592::AID-IMMU592>3.0.CO;2-2     Document Type: Article

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