Deconstruction of the ras switching cycle through saturation mutagenesis

eLife

Volumn 6, Issue , 2017, Pages

  Bandaru, Pradeep ^a,b   Shah, Neel H ^a,b   Bhattacharyya, Moitrayee ^a,b   Barton, John P ^c,d   Kondo, Yasushi ^a,b   Cofsky, Joshua C ^a,b   Gee, Christine L ^a,b   Chakraborty, Arup K ^c,d   Kortemme, Tanja ^e   Ranganathan, Rama ^f,g   Kuriyan, John ^a,b,h  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d Massachusetts Institute of Technology Cambridge   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^g UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^h LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; RAS PROTEIN;

ARTICLE; BIOCHEMICAL ANALYSIS; COMPARATIVE STUDY; CONCEPTUAL FRAMEWORK; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA ISOLATION; DYNAMICS; ESCHERICHIA COLI; GENE SWITCHING; GENETIC VARIABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; ION EXCHANGE CHROMATOGRAPHY; MUTAGENESIS; NONHUMAN; PLASMID; POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SIMULATION; SOMATIC MUTATION; THERMODYNAMICS; TISSUE OXYGENATION; CONSERVED SEQUENCE; DNA MUTATIONAL ANALYSIS; GENETICS; HUMAN; METABOLISM; MOLECULAR EVOLUTION; PROTEIN PROTEIN INTERACTION;

CONSERVED SEQUENCE; DNA MUTATIONAL ANALYSIS; EVOLUTION, MOLECULAR; HUMANS; MUTAGENESIS; PROTEIN INTERACTION MAPS; RAS PROTEINS;

EID: 85026911695     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.27810     Document Type: Article

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