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Volumn 117, Issue , 2020, Pages 198-210

Prenatal stress and epigenetics

Author keywords

DNA methylation; DOHaD; Epigenetics; Prenatal stress

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; HYDROCORTISONE; SEROTONIN TRANSPORTER;

EID: 85020462270     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2017.05.016     Document Type: Review
Times cited : (136)

References (170)
  • 1
    • 85047694610 scopus 로고    scopus 로고
    • Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression
    • Alikhani-Koopaei, R., Fouladkou, F., Frey, F.J., Frey, B.M., Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression. J. Clin. Invest. 114 (2004), 1146–1157, 10.1172/JCI21647.
    • (2004) J. Clin. Invest. , vol.114 , pp. 1146-1157
    • Alikhani-Koopaei, R.1    Fouladkou, F.2    Frey, F.J.3    Frey, B.M.4
  • 2
    • 0025358336 scopus 로고
    • Diurnal salivary cortisol patterns during pregnancy and after delivery: relationship to plasma corticotrophin-releasing-hormone
    • Allolio, B., Hoffmann, J., Linton, E.A., Winkelmann, W., Kusche, M., Schulte, H.M., Diurnal salivary cortisol patterns during pregnancy and after delivery: relationship to plasma corticotrophin-releasing-hormone. Clin. Endocrinol. (Oxf.) 33 (1990), 279–289.
    • (1990) Clin. Endocrinol. (Oxf.) , vol.33 , pp. 279-289
    • Allolio, B.1    Hoffmann, J.2    Linton, E.A.3    Winkelmann, W.4    Kusche, M.5    Schulte, H.M.6
  • 3
    • 84883550548 scopus 로고    scopus 로고
    • Patterning in placental 11-B hydroxysteroid dehydrogenase methylation according to prenatal socioeconomic adversity
    • Appleton, A.A., Armstrong, D.A., Lesseur, C., Lee, J., Padbury, J.F., Lester, B.M., Marsit, C.J., Patterning in placental 11-B hydroxysteroid dehydrogenase methylation according to prenatal socioeconomic adversity. PLoS One, 8, 2013, e74691, 10.1371/journal.pone.0074691.
    • (2013) PLoS One , vol.8 , pp. e74691
    • Appleton, A.A.1    Armstrong, D.A.2    Lesseur, C.3    Lee, J.4    Padbury, J.F.5    Lester, B.M.6    Marsit, C.J.7
  • 5
    • 84913580377 scopus 로고    scopus 로고
    • Stress-induced perinatal and transgenerational epigenetic programming of brain development and mental health
    • Babenko, O., Kovalchuk, I., Metz, G.A.S., Stress-induced perinatal and transgenerational epigenetic programming of brain development and mental health. Neurosci. Biobehav. Rev. 48 (2015), 70–91, 10.1016/j.neubiorev.2014.11.013.
    • (2015) Neurosci. Biobehav. Rev. , vol.48 , pp. 70-91
    • Babenko, O.1    Kovalchuk, I.2    Metz, G.A.S.3
  • 7
    • 0025081078 scopus 로고
    • The fetal and infant origins of adult disease
    • Barker, D.J., The fetal and infant origins of adult disease. Br. Med. J., 301, 1990, 1111.
    • (1990) Br. Med. J. , vol.301 , pp. 1111
    • Barker, D.J.1
  • 8
    • 0029082045 scopus 로고
    • The fetal and infant origins of disease
    • Barker, D.J., The fetal and infant origins of disease. Eur. J. Clin. Invest. 25 (1995), 457–463.
    • (1995) Eur. J. Clin. Invest. , vol.25 , pp. 457-463
    • Barker, D.J.1
  • 9
    • 11844250659 scopus 로고    scopus 로고
    • The developmental origins of adult disease
    • Barker, D.J.P., The developmental origins of adult disease. J. Am. Coll. Nutr. 23 (2004), 588S–595S.
    • (2004) J. Am. Coll. Nutr. , vol.23 , pp. 588S-595S
    • Barker, D.J.P.1
  • 10
    • 0023020183 scopus 로고
    • The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations
    • Baron, R.H., Kenny, D.A., The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J. Pers. Soc. Psychol. 51 (1986), 1173–1182.
    • (1986) J. Pers. Soc. Psychol. , vol.51 , pp. 1173-1182
    • Baron, R.H.1    Kenny, D.A.2
  • 11
    • 0025274810 scopus 로고
    • Expressed emotion and first-admission schizophrenia: nine-month follow-up in a French cultural environment
    • Barrelet, L., Ferrero, F., Szigethy, L., Giddey, C., Pellizzer, G., Expressed emotion and first-admission schizophrenia: nine-month follow-up in a French cultural environment. Br. J. Psychiatry 156 (1990), 357–362.
    • (1990) Br. J. Psychiatry , vol.156 , pp. 357-362
    • Barrelet, L.1    Ferrero, F.2    Szigethy, L.3    Giddey, C.4    Pellizzer, G.5
  • 12
    • 84945462482 scopus 로고    scopus 로고
    • Severe childhood obesity: an under-recognised and growing health problem
    • Bass, R., Eneli, I., Severe childhood obesity: an under-recognised and growing health problem. Postgrad. Med. J., 2015, 10.1136/postgradmedj-2014-133033.
    • (2015) Postgrad. Med. J.
    • Bass, R.1    Eneli, I.2
  • 13
    • 0032554555 scopus 로고    scopus 로고
    • Understanding human parturition
    • Benediktsson, R., Seckl, J.R., Understanding human parturition. Lancet 351 (1998), 913–914, 10.1016/S0140-6736(05)70335-4.
    • (1998) Lancet , vol.351 , pp. 913-914
    • Benediktsson, R.1    Seckl, J.R.2
  • 14
    • 0027509970 scopus 로고
    • Glucocorticoid exposure in utero: new model for adult hypertension
    • Benediktsson, R., Lindsay, R.S., Noble, J., Seckl, J.R., Edwards, C.R., Glucocorticoid exposure in utero: new model for adult hypertension. Lancet 341 (1993), 339–341.
    • (1993) Lancet , vol.341 , pp. 339-341
    • Benediktsson, R.1    Lindsay, R.S.2    Noble, J.3    Seckl, J.R.4    Edwards, C.R.5
  • 15
    • 84920896517 scopus 로고    scopus 로고
    • Prenatal stress induces spatial memory deficits and epigenetic changes in the hippocampus indicative of heterochromatin formation and reduced gene expression
    • Benoit, J.D., Rakic, P., Frick, K.M., Prenatal stress induces spatial memory deficits and epigenetic changes in the hippocampus indicative of heterochromatin formation and reduced gene expression. Behav. Brain Res. 281 (2015), 1–8, 10.1016/j.bbr.2014.12.001.
    • (2015) Behav. Brain Res. , vol.281 , pp. 1-8
    • Benoit, J.D.1    Rakic, P.2    Frick, K.M.3
  • 16
    • 0021927762 scopus 로고
    • Tissue-specific hypomethylation and expression of rat phosphoenolpyruvate carboxykinase gene induced by in vivo treatment of fetuses and neonates with 5-azacytidine
    • Benvenisty, N., Szyf, M., Mencher, D., Razin, A., Reshef, L., Tissue-specific hypomethylation and expression of rat phosphoenolpyruvate carboxykinase gene induced by in vivo treatment of fetuses and neonates with 5-azacytidine. Biochemistry 24 (1985), 5015–5019.
    • (1985) Biochemistry , vol.24 , pp. 5015-5019
    • Benvenisty, N.1    Szyf, M.2    Mencher, D.3    Razin, A.4    Reshef, L.5
  • 17
    • 48749105928 scopus 로고    scopus 로고
    • Physical and mental health outcomes of prenatal maternal stress in human and animal studies: a review of recent evidence
    • Beydoun, H., Saftlas, A.F., Physical and mental health outcomes of prenatal maternal stress in human and animal studies: a review of recent evidence. Paediatr. Perinat. Epidemiol. 22 (2008), 438–466.
    • (2008) Paediatr. Perinat. Epidemiol. , vol.22 , pp. 438-466
    • Beydoun, H.1    Saftlas, A.F.2
  • 19
    • 84941349141 scopus 로고    scopus 로고
    • Maternal prenatal depressive symptoms predict infant NR3C1 1F and BDNF IV DNA methylation
    • Braithwaite, E.C., Kundakovic, M., Ramchandani, P.G., Murphy, S.E., Champagne, F.A., Maternal prenatal depressive symptoms predict infant NR3C1 1F and BDNF IV DNA methylation. Epigenetics 10 (2015), 408–417, 10.1080/15592294.2015.1039221.
    • (2015) Epigenetics , vol.10 , pp. 408-417
    • Braithwaite, E.C.1    Kundakovic, M.2    Ramchandani, P.G.3    Murphy, S.E.4    Champagne, F.A.5
  • 20
    • 84907187132 scopus 로고    scopus 로고
    • DNA methylation signatures triggered by prenatal maternal stress exposure to a natural disaster: project ice storm
    • Cao-Lei, L., Massart, R., Suderman, M.J., Machnes, Z., Elgbeili, G., Laplante, D.P., Szyf, M., King, S., DNA methylation signatures triggered by prenatal maternal stress exposure to a natural disaster: project ice storm. PLoS One, 9, 2014, e107653, 10.1371/journal.pone.0107653.
    • (2014) PLoS One , vol.9 , pp. e107653
    • Cao-Lei, L.1    Massart, R.2    Suderman, M.J.3    Machnes, Z.4    Elgbeili, G.5    Laplante, D.P.6    Szyf, M.7    King, S.8
  • 21
    • 84943775007 scopus 로고    scopus 로고
    • DNA methylation mediates the impact of exposure to prenatal maternal stress on BMI and central adiposity in children at age 13(1/2) years: project Ice Storm
    • Cao-Lei, L., Dancause, K.N., Elgbeili, G., Massart, R., Szyf, M., Liu, A., Laplante, D.P., King, S., DNA methylation mediates the impact of exposure to prenatal maternal stress on BMI and central adiposity in children at age 13(1/2) years: project Ice Storm. Epigenetics 10 (2015), 749–761, 10.1080/15592294.2015.1063771.
    • (2015) Epigenetics , vol.10 , pp. 749-761
    • Cao-Lei, L.1    Dancause, K.N.2    Elgbeili, G.3    Massart, R.4    Szyf, M.5    Liu, A.6    Laplante, D.P.7    King, S.8
  • 22
    • 84927759279 scopus 로고    scopus 로고
    • Pregnant women's cognitive appraisal from a natural disaster affects DNA methylation in their children 13 years later: project Ice Storm
    • Cao-Lei, L., Elgbeili, G., Massart, R., Laplante, D.P., Szyf, M., King, S., Pregnant women's cognitive appraisal from a natural disaster affects DNA methylation in their children 13 years later: project Ice Storm. Transl. Psychiatry, 5, 2015, 10.1038/tp.2015.13.
    • (2015) Transl. Psychiatry , vol.5
    • Cao-Lei, L.1    Elgbeili, G.2    Massart, R.3    Laplante, D.P.4    Szyf, M.5    King, S.6
  • 23
    • 84990060770 scopus 로고    scopus 로고
    • Pregnant women's cognitive appraisal of a natural disaster affects their children's BMI and central adiposity via DNA methylation: project Ice Storm
    • Cao-Lei, L., Dancause, K.N., Elgbeili, G., Laplante, D.P., Szyf, M., King, S., Pregnant women's cognitive appraisal of a natural disaster affects their children's BMI and central adiposity via DNA methylation: project Ice Storm. Early Hum. Dev. 103 (2016), 189–192, 10.1016/j.earlhumdev.2016.09.013.
    • (2016) Early Hum. Dev. , vol.103 , pp. 189-192
    • Cao-Lei, L.1    Dancause, K.N.2    Elgbeili, G.3    Laplante, D.P.4    Szyf, M.5    King, S.6
  • 24
    • 84971500451 scopus 로고    scopus 로고
    • DNA methylation mediates the effect of exposure to prenatal maternal stress on cytokine production in children at age 13½ years: project Ice Storm
    • Cao-Lei, L., Veru, F., Elgbeili, G., Szyf, M., Laplante, D.P., King, S., DNA methylation mediates the effect of exposure to prenatal maternal stress on cytokine production in children at age 13½ years: project Ice Storm. Clin. Epigenet. 8 (2016), 1–15, 10.1186/s13148-016-0219-0.
    • (2016) Clin. Epigenet. , vol.8 , pp. 1-15
    • Cao-Lei, L.1    Veru, F.2    Elgbeili, G.3    Szyf, M.4    Laplante, D.P.5    King, S.6
  • 26
    • 0026536665 scopus 로고
    • The concept of stress and stress systems disorders
    • Chrousos, G.P., Gold, P.W., The concept of stress and stress systems disorders. J. Am. Med. Assoc. 267 (1992), 1244–1252.
    • (1992) J. Am. Med. Assoc. , vol.267 , pp. 1244-1252
    • Chrousos, G.P.1    Gold, P.W.2
  • 27
    • 0037372162 scopus 로고    scopus 로고
    • Programming of rat muscle and fat metabolism by in utero overexposure to glucocorticoids
    • Cleasby, M.E., Kelly, P.A., Walker, B.R., Seckl, J.R., Programming of rat muscle and fat metabolism by in utero overexposure to glucocorticoids. Endocrinology 144 (2003), 999–1007, 10.1210/en.2002-220559.
    • (2003) Endocrinology , vol.144 , pp. 999-1007
    • Cleasby, M.E.1    Kelly, P.A.2    Walker, B.R.3    Seckl, J.R.4
  • 29
    • 84888796582 scopus 로고    scopus 로고
    • The roles of DNA methylation of NR3C1 and 11beta-HSD2 and exposure to maternal mood disorder in utero on newborn neurobehavior
    • Conradt, E., Lester, B.M., Appleton, A.A., Armstrong, D.A., Marsit, C.J., The roles of DNA methylation of NR3C1 and 11beta-HSD2 and exposure to maternal mood disorder in utero on newborn neurobehavior. Epigenetics 8 (2013), 1321–1329, 10.4161/epi.26634.
    • (2013) Epigenetics , vol.8 , pp. 1321-1329
    • Conradt, E.1    Lester, B.M.2    Appleton, A.A.3    Armstrong, D.A.4    Marsit, C.J.5
  • 30
    • 0018649823 scopus 로고
    • Maternal anxiety and obstetric complications
    • Crandon, A.J., Maternal anxiety and obstetric complications. J. Psychosom. Res. 23 (1979), 109–111.
    • (1979) J. Psychosom. Res. , vol.23 , pp. 109-111
    • Crandon, A.J.1
  • 31
    • 84862743106 scopus 로고    scopus 로고
    • Prenatal synthetic glucocorticoid treatment changes DNA methylation states in male organ systems: multigenerational effects
    • Crudo, A., Petropoulos, S., Moisiadis, V.G., Iqbal, M., Kostaki, A., Machnes, Z., Szyf, M., Matthews, S.G., Prenatal synthetic glucocorticoid treatment changes DNA methylation states in male organ systems: multigenerational effects. Endocrinology 153 (2012), 3269–3283, 10.1210/en.2011-2160.
    • (2012) Endocrinology , vol.153 , pp. 3269-3283
    • Crudo, A.1    Petropoulos, S.2    Moisiadis, V.G.3    Iqbal, M.4    Kostaki, A.5    Machnes, Z.6    Szyf, M.7    Matthews, S.G.8
  • 32
    • 84886454386 scopus 로고    scopus 로고
    • Effects of antenatal synthetic glucocorticoid on glucocorticoid receptor binding, DNA methylation, and genome-wide mRNA levels in the fetal male hippocampus
    • Crudo, A., Petropoulos, S., Suderman, M., Moisiadis, V.G., Kostaki, A., Hallett, M., Szyf, M., Matthews, S.G., Effects of antenatal synthetic glucocorticoid on glucocorticoid receptor binding, DNA methylation, and genome-wide mRNA levels in the fetal male hippocampus. Endocrinology 154 (2013), 4170–4181, 10.1210/en. 2013-1484.
    • (2013) Endocrinology , vol.154 , pp. 4170-4181
    • Crudo, A.1    Petropoulos, S.2    Suderman, M.3    Moisiadis, V.G.4    Kostaki, A.5    Hallett, M.6    Szyf, M.7    Matthews, S.G.8
  • 34
    • 84988221547 scopus 로고    scopus 로고
    • Relationship between expression and methylation of obesity-related genes in children
    • Dave, V., Yousefi, P., Huen, K., Volberg, V., Holland, N., Relationship between expression and methylation of obesity-related genes in children. Mutagenesis 30 (2015), 411–420, 10.1093/mutage/geu089.
    • (2015) Mutagenesis , vol.30 , pp. 411-420
    • Dave, V.1    Yousefi, P.2    Huen, K.3    Volberg, V.4    Holland, N.5
  • 35
    • 76749118188 scopus 로고    scopus 로고
    • The timing of prenatal exposure to maternal cortisol and psychosocial stress is associated with human infant cognitive development
    • Davis, E.P., Sandman, C.A., The timing of prenatal exposure to maternal cortisol and psychosocial stress is associated with human infant cognitive development. Child Dev. 81 (2010), 131–148.
    • (2010) Child Dev. , vol.81 , pp. 131-148
    • Davis, E.P.1    Sandman, C.A.2
  • 36
    • 78651487878 scopus 로고    scopus 로고
    • Prenatal maternal stress programs infant stress regulation
    • Davis, E.P., Glynn, L.M., Waffarn, F., Sandman, C.A., Prenatal maternal stress programs infant stress regulation. J. Child Psychol. Psychiatry 52 (2011), 119–129, 10.1111/j.1469-7610.2010.02314.x.
    • (2011) J. Child Psychol. Psychiatry , vol.52 , pp. 119-129
    • Davis, E.P.1    Glynn, L.M.2    Waffarn, F.3    Sandman, C.A.4
  • 38
    • 84875231925 scopus 로고    scopus 로고
    • Neonatal exposure to low dose corticosterone persistently modulates hippocampal mineralocorticoid receptor expression and improves locomotor/exploratory behaviour in a mouse model of Rett syndrome
    • De Filippis, B., Ricceri, L., Fuso, A., Laviola, G., Neonatal exposure to low dose corticosterone persistently modulates hippocampal mineralocorticoid receptor expression and improves locomotor/exploratory behaviour in a mouse model of Rett syndrome. Neuropharmacology 68 (2013), 174–183, 10.1016/j.neuropharm.2012.05.048.
    • (2013) Neuropharmacology , vol.68 , pp. 174-183
    • De Filippis, B.1    Ricceri, L.2    Fuso, A.3    Laviola, G.4
  • 39
    • 77957880665 scopus 로고    scopus 로고
    • Prenatal exposure to maternal depressed mood and the MTHFR C677T variant affect SLC6A4 methylation in infants at birth
    • (Electronic Resource)
    • Devlin, A.M., Brain, U., Austin, J., Oberlander, T.F., Prenatal exposure to maternal depressed mood and the MTHFR C677T variant affect SLC6A4 methylation in infants at birth. PLoS One, 5, 2010, e12201 (Electronic Resource).
    • (2010) PLoS One , vol.5 , pp. e12201
    • Devlin, A.M.1    Brain, U.2    Austin, J.3    Oberlander, T.F.4
  • 40
    • 2142779128 scopus 로고    scopus 로고
    • The role of prenatal maternal stress in child development
    • DiPietro, J.A., The role of prenatal maternal stress in child development. Curr. Direct. Psychol. Sci. 13 (2004), 71–74.
    • (2004) Curr. Direct. Psychol. Sci. , vol.13 , pp. 71-74
    • DiPietro, J.A.1
  • 41
    • 84893691607 scopus 로고    scopus 로고
    • Parental olfactory experience influences behavior and neural structure in subsequent generations
    • Dias, B.G., Ressler, K.J., Parental olfactory experience influences behavior and neural structure in subsequent generations. Nat. Neurosci. 17 (2014), 89–96, 10.1038/nn.3594.
    • (2014) Nat. Neurosci. , vol.17 , pp. 89-96
    • Dias, B.G.1    Ressler, K.J.2
  • 43
    • 84886396060 scopus 로고    scopus 로고
    • Changes in the maternal hypothalamic-pituitary-adrenal axis in pregnancy and postpartum: influences on maternal and fetal outcomes
    • Duthie, L., Reynolds, R.M., Changes in the maternal hypothalamic-pituitary-adrenal axis in pregnancy and postpartum: influences on maternal and fetal outcomes. Neuroendocrinology 98 (2013), 106–115, 10.1159/000354702.
    • (2013) Neuroendocrinology , vol.98 , pp. 106-115
    • Duthie, L.1    Reynolds, R.M.2
  • 44
    • 33845623786 scopus 로고    scopus 로고
    • Stress in pregnancy and infant HPA axis function: conceptual and methodological issues relating to the use of salivary cortisol as an outcome measure
    • Egliston, K.A., McMahon, C., Austin, M.P., Stress in pregnancy and infant HPA axis function: conceptual and methodological issues relating to the use of salivary cortisol as an outcome measure. Psychoneuroendocrinology 32 (2007), 1–13.
    • (2007) Psychoneuroendocrinology , vol.32 , pp. 1-13
    • Egliston, K.A.1    McMahon, C.2    Austin, M.P.3
  • 45
    • 84908455441 scopus 로고    scopus 로고
    • Independent and additive association of prenatal famine exposure and intermediary life conditions with adult mortality between age 18–63 years
    • Ekamper, P., van Poppel, F., Stein, A.D., Lumey, L.H., Independent and additive association of prenatal famine exposure and intermediary life conditions with adult mortality between age 18–63 years. Soc. Sci. Med. 119 (2014), 232–239, 10.1016/j.socscimed.2013.10.027.
    • (2014) Soc. Sci. Med. , vol.119 , pp. 232-239
    • Ekamper, P.1    van Poppel, F.2    Stein, A.D.3    Lumey, L.H.4
  • 46
    • 3042749817 scopus 로고    scopus 로고
    • Glucocorticoids and the Th1/Th2 balance
    • Elenkov, I.J., Glucocorticoids and the Th1/Th2 balance. Ann. N.Y. Acad. Sci. 1024 (2004), 138–146.
    • (2004) Ann. N.Y. Acad. Sci. , vol.1024 , pp. 138-146
    • Elenkov, I.J.1
  • 47
  • 48
    • 84867562587 scopus 로고    scopus 로고
    • Fetal programming of body composition, obesity, and metabolic function: the role of intrauterine stress and stress biology
    • Entringer, S., Buss, C., Swanson, J.M., Cooper, D.M., Wing, D.A., Waffarn, F., Wadhwa, P.D., Fetal programming of body composition, obesity, and metabolic function: the role of intrauterine stress and stress biology. J. Nutr. Metab., 63254, 2012, 8, 10.1155/2012/632548.
    • (2012) J. Nutr. Metab. , vol.63254 , pp. 8
    • Entringer, S.1    Buss, C.2    Swanson, J.M.3    Cooper, D.M.4    Wing, D.A.5    Waffarn, F.6    Wadhwa, P.D.7
  • 49
    • 28244484381 scopus 로고    scopus 로고
    • Early growth and adult health outcomes-lessons learned from the Helsinki Birth Cohort Study
    • Eriksson, J.G., Early growth and adult health outcomes-lessons learned from the Helsinki Birth Cohort Study. Matern. Child Nutr. 1 (2005), 149–154, 10.1111/j.1740-8709.2005.00017.x.
    • (2005) Matern. Child Nutr. , vol.1 , pp. 149-154
    • Eriksson, J.G.1
  • 50
    • 77957555449 scopus 로고    scopus 로고
    • Early programming of later health and disease: factors acting during prenatal life might have lifelong consequences
    • Eriksson, J.G., Early programming of later health and disease: factors acting during prenatal life might have lifelong consequences. Diabetes 59 (2010), 2349–2350, 10.2337/db10-0878.
    • (2010) Diabetes , vol.59 , pp. 2349-2350
    • Eriksson, J.G.1
  • 51
    • 84872942417 scopus 로고    scopus 로고
    • Epigenetic vestiges of early developmental adversity: childhood stress exposure and DNA methylation in adolescence
    • Essex, M.J., Boyce, W.T., Hertzman, C., Lam, L.L., Armstrong, J.M., Neumann, S.M., Kobor, M.S., Epigenetic vestiges of early developmental adversity: childhood stress exposure and DNA methylation in adolescence. Child Dev. 84 (2013), 58–75, 10.1111/j.1467-8624.2011.01641.x.
    • (2013) Child Dev. , vol.84 , pp. 58-75
    • Essex, M.J.1    Boyce, W.T.2    Hertzman, C.3    Lam, L.L.4    Armstrong, J.M.5    Neumann, S.M.6    Kobor, M.S.7
  • 52
    • 47149109800 scopus 로고    scopus 로고
    • Pregnant women's cortisol is elevated with anxiety and depression − but only when comorbid
    • Evans, L.M., Myers, M.M., Monk, C., Pregnant women's cortisol is elevated with anxiety and depression − but only when comorbid. Arch. Womens Ment. Health 11 (2008), 239–248, 10.1007/s00737-008-0019-4.
    • (2008) Arch. Womens Ment. Health , vol.11 , pp. 239-248
    • Evans, L.M.1    Myers, M.M.2    Monk, C.3
  • 53
    • 0022413940 scopus 로고
    • Effects of ultrasound feedback on pregnancy anxiety, fetal activity, and neonatal outcome
    • Field, T., Sandberg, D., Quetel, T.A., Garcia, R., Rosario, M., Effects of ultrasound feedback on pregnancy anxiety, fetal activity, and neonatal outcome. Obstet. Gynecol. 66 (1985), 525–528.
    • (1985) Obstet. Gynecol. , vol.66 , pp. 525-528
    • Field, T.1    Sandberg, D.2    Quetel, T.A.3    Garcia, R.4    Rosario, M.5
  • 55
    • 67349190274 scopus 로고    scopus 로고
    • Sexual dimorphism in environmental epigenetic programming
    • Gabory, A., Attig, L., Junien, C., Sexual dimorphism in environmental epigenetic programming. Mol. Cell. Endocrinol. 304 (2009), 8–18, 10.1016/j.mce.2009.02.015.
    • (2009) Mol. Cell. Endocrinol. , vol.304 , pp. 8-18
    • Gabory, A.1    Attig, L.2    Junien, C.3
  • 57
    • 0032578312 scopus 로고    scopus 로고
    • Fetal exposure to maternal cortisol
    • Gitau, R., Cameron, A., Fisk, N.M., Glover, V., Fetal exposure to maternal cortisol. Lancet 352 (1998), 707–708.
    • (1998) Lancet , vol.352 , pp. 707-708
    • Gitau, R.1    Cameron, A.2    Fisk, N.M.3    Glover, V.4
  • 58
    • 9944233595 scopus 로고    scopus 로고
    • Stress-associated immune dysregulation and its importance for human health: a personal history of psychoneuroimmunology Brain
    • Glaser, R., Stress-associated immune dysregulation and its importance for human health: a personal history of psychoneuroimmunology Brain. Behav. Immun. 19 (2005), 3–11.
    • (2005) Behav. Immun. , vol.19 , pp. 3-11
    • Glaser, R.1
  • 59
    • 79952683347 scopus 로고    scopus 로고
    • Annual Research Review: prenatal stress and the origins of psychopathology: an evolutionary perspective
    • Glover, V., Annual Research Review: prenatal stress and the origins of psychopathology: an evolutionary perspective. J. Child Psychol. Psychiatry 52 (2011), 356–367, 10.1111/j.1469-7610.2011.02371.x.
    • (2011) J. Child Psychol. Psychiatry , vol.52 , pp. 356-367
    • Glover, V.1
  • 60
    • 84926519306 scopus 로고    scopus 로고
    • Prenatal stress and its effects on the fetus and the child: possible underlying biological mechanisms
    • Glover, V., Prenatal stress and its effects on the fetus and the child: possible underlying biological mechanisms. Adv. Neurobiol. 10 (2015), 269–283, 10.1007/978-1-4939-1372-5_13.
    • (2015) Adv. Neurobiol. , vol.10 , pp. 269-283
    • Glover, V.1
  • 61
    • 84975889019 scopus 로고    scopus 로고
    • A conceptual framework for the developmental origins of health and disease
    • Gluckman, P.D., Hanson, M.A., Buklijas, T., A conceptual framework for the developmental origins of health and disease. J. Dev. Origins Health Dis. 1 (2010), 6–18, 10.1017/S2040174409990171.
    • (2010) J. Dev. Origins Health Dis. , vol.1 , pp. 6-18
    • Gluckman, P.D.1    Hanson, M.A.2    Buklijas, T.3
  • 62
    • 0010519166 scopus 로고
    • Psychological tension in pregnancy
    • Grimm, E.G., Psychological tension in pregnancy. Psychosom. Med. 23 (1961), 520–527.
    • (1961) Psychosom. Med. , vol.23 , pp. 520-527
    • Grimm, E.G.1
  • 63
    • 17844406663 scopus 로고    scopus 로고
    • Maternal prenatal stress and 4–6 year old children's salivary cortisol concentrations pre- and post-vaccination
    • Gutteling, B.M., de Weerth, C., Buitelaar, J.K., Maternal prenatal stress and 4–6 year old children's salivary cortisol concentrations pre- and post-vaccination. Stress 7 (2004), 257–260, 10.1080/10253890500044521.
    • (2004) Stress , vol.7 , pp. 257-260
    • Gutteling, B.M.1    de Weerth, C.2    Buitelaar, J.K.3
  • 64
    • 16244374298 scopus 로고    scopus 로고
    • Prenatal stress and children's cortisol reaction to the first day of school
    • Gutteling, B.M., de Weerth, C., Buitelaar, J.K., Prenatal stress and children's cortisol reaction to the first day of school. Psychoneuroendocrinology 30 (2005), 541–549.
    • (2005) Psychoneuroendocrinology , vol.30 , pp. 541-549
    • Gutteling, B.M.1    de Weerth, C.2    Buitelaar, J.K.3
  • 66
    • 84903733708 scopus 로고    scopus 로고
    • Prenatal adverse life events increase the risk for atopic diseases in children, which is enhanced in the absence of a maternal atopic predisposition
    • Hartwig, I.R., Sly, P.D., Schmidt, L.A., van Lieshout, R.J., Bienenstock, J., Holt, P.G., Arck, P.C., Prenatal adverse life events increase the risk for atopic diseases in children, which is enhanced in the absence of a maternal atopic predisposition. J. Allergy Clin. Immunol. 134 (2014), 160–169, 10.1016/j.jaci.2014.01.033.
    • (2014) J. Allergy Clin. Immunol. , vol.134 , pp. 160-169
    • Hartwig, I.R.1    Sly, P.D.2    Schmidt, L.A.3    van Lieshout, R.J.4    Bienenstock, J.5    Holt, P.G.6    Arck, P.C.7
  • 67
    • 84870854437 scopus 로고    scopus 로고
    • Introduction to Mediation, Moderation, and Conditional Process Analysis
    • The Guilford Press New York
    • Hayes, A.F., Introduction to Mediation, Moderation, and Conditional Process Analysis. 2013, The Guilford Press, New York.
    • (2013)
    • Hayes, A.F.1
  • 71
    • 0347568319 scopus 로고    scopus 로고
    • Prenatal stress and risk for psychopathology: specific effects or induction of general susceptibility?
    • Huizink, A.C., Mulder, E.J., Buitelaar, J.K., Prenatal stress and risk for psychopathology: specific effects or induction of general susceptibility?. Psychol. Bull. 130 (2004), 115–142.
    • (2004) Psychol. Bull. , vol.130 , pp. 115-142
    • Huizink, A.C.1    Mulder, E.J.2    Buitelaar, J.K.3
  • 72
    • 84893192328 scopus 로고    scopus 로고
    • Accounting for cellular heterogeneity is critical in epigenome-wide association studies
    • Jaffe, A.E., Irizarry, R.A., Accounting for cellular heterogeneity is critical in epigenome-wide association studies. Genome Biol., 15, 2014, R31, 10.1186/gb-2014-15-2-r31.
    • (2014) Genome Biol. , vol.15 , pp. R31
    • Jaffe, A.E.1    Irizarry, R.A.2
  • 74
    • 84862750379 scopus 로고    scopus 로고
    • Epigenetic effects of prenatal stress on 11beta-hydroxysteroid dehydrogenase-2 in the placenta and fetal brain
    • Jensen Pena, C., Monk, C., Champagne, F.A., Epigenetic effects of prenatal stress on 11beta-hydroxysteroid dehydrogenase-2 in the placenta and fetal brain. PLoS One, 7, 2012, e39791, 10.1371/journal.pone.0039791.
    • (2012) PLoS One , vol.7 , pp. e39791
    • Jensen Pena, C.1    Monk, C.2    Champagne, F.A.3
  • 75
    • 1342325346 scopus 로고    scopus 로고
    • DNA methylation may restrict but does not determine differential gene expression at the Sgy/Tead2 locus during mouse development
    • Kaneko, K.J., Rein, T., Guo, Z.S., Latham, K., DePamphilis, M.L., DNA methylation may restrict but does not determine differential gene expression at the Sgy/Tead2 locus during mouse development. Mol. Cell. Biol. 24 (2004), 1968–1982.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 1968-1982
    • Kaneko, K.J.1    Rein, T.2    Guo, Z.S.3    Latham, K.4    DePamphilis, M.L.5
  • 76
    • 40749107391 scopus 로고    scopus 로고
    • Fetal programming of hypothalamic-pituitary-adrenal (HPA) axis function and behavior by synthetic glucocorticoids
    • Kapoor, A., Petropoulos, S., Matthews, S.G., Fetal programming of hypothalamic-pituitary-adrenal (HPA) axis function and behavior by synthetic glucocorticoids. Brain Res. Rev. 57 (2008), 586–595.
    • (2008) Brain Res. Rev. , vol.57 , pp. 586-595
    • Kapoor, A.1    Petropoulos, S.2    Matthews, S.G.3
  • 77
    • 84940960421 scopus 로고    scopus 로고
    • Combined dyslipidemia in childhood
    • Kavey, R.E., Combined dyslipidemia in childhood. J. Clin. Lipidol. 9 (2015), S41–56, 10.1016/j.jacl.2015.06.008.
    • (2015) J. Clin. Lipidol. , vol.9 , pp. S41-56
    • Kavey, R.E.1
  • 79
    • 84969256736 scopus 로고    scopus 로고
    • Stress transgenerationally programs metabolic pathways linked to altered mental health
    • Kiss, D., Ambeskovic, M., Montina, T., Metz, G.A.S., Stress transgenerationally programs metabolic pathways linked to altered mental health. Cell. Mol. Life Sci., 2016, 1–11, 10.1007/s00018-016-2272-4.
    • (2016) Cell. Mol. Life Sci. , pp. 1-11
    • Kiss, D.1    Ambeskovic, M.2    Montina, T.3    Metz, G.A.S.4
  • 80
    • 0027195615 scopus 로고
    • The neurotrophic factor concept: a reexamination
    • Korsching, S., The neurotrophic factor concept: a reexamination. J. Neurosci. 13 (1993), 2739–2748.
    • (1993) J. Neurosci. , vol.13 , pp. 2739-2748
    • Korsching, S.1
  • 82
    • 0003704999 scopus 로고
    • Stress, Appraisal and Coping
    • Springer N.Y
    • Lazarus, R.S., Folkman, S., Stress, Appraisal and Coping. 1984, Springer, N.Y.
    • (1984)
    • Lazarus, R.S.1    Folkman, S.2
  • 83
    • 0003961932 scopus 로고
    • Psychological Stress and the Coping Process
    • McGraw-Hill New York
    • Lazarus, R.S., Psychological Stress and the Coping Process. 1966, McGraw-Hill, New York.
    • (1966)
    • Lazarus, R.S.1
  • 84
    • 2942530662 scopus 로고    scopus 로고
    • Prenatal stress induces intrauterine growth restriction and programmes glucose intolerance and feeding behaviour disturbances in the aged rat
    • Lesage, J., Del-Favero, F., Leonhardt, M., Louvart, H., Maccari, S., Vieau, D., Darnaudery, M., Prenatal stress induces intrauterine growth restriction and programmes glucose intolerance and feeding behaviour disturbances in the aged rat. J. Endocrinol. 181 (2004), 291–296, 10.1677/joe.0.1810291.
    • (2004) J. Endocrinol. , vol.181 , pp. 291-296
    • Lesage, J.1    Del-Favero, F.2    Leonhardt, M.3    Louvart, H.4    Maccari, S.5    Vieau, D.6    Darnaudery, M.7
  • 85
    • 84865523902 scopus 로고    scopus 로고
    • Prenatal exposure to bereavement and type-2 diabetes: a Danish longitudinal population based study
    • Li, J., Olsen, J., Vestergaard, M., Obel, C., Kristensen, J.K., Virk, J., Prenatal exposure to bereavement and type-2 diabetes: a Danish longitudinal population based study. PLoS One, 7, 2012, e43508, 10.1371/journal.pone.0043508.
    • (2012) PLoS One , vol.7 , pp. e43508
    • Li, J.1    Olsen, J.2    Vestergaard, M.3    Obel, C.4    Kristensen, J.K.5    Virk, J.6
  • 86
    • 0029989854 scopus 로고    scopus 로고
    • Prenatal glucocorticoid exposure leads to offspring hyperglycaemia in the rat: studies with the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone
    • Lindsay, R.S., Lindsay, R.M., Waddell, B.J., Seckl, J.R., Prenatal glucocorticoid exposure leads to offspring hyperglycaemia in the rat: studies with the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone. Diabetologia 39 (1996), 1299–1305.
    • (1996) Diabetologia , vol.39 , pp. 1299-1305
    • Lindsay, R.S.1    Lindsay, R.M.2    Waddell, B.J.3    Seckl, J.R.4
  • 88
    • 77951162858 scopus 로고    scopus 로고
    • Mediation analyses: applications in nutrition research and reading the literature
    • Lockwood, C.M., DeFrancesco, C.A., Elliot, D.L., Beresford, S.A., Toobert, D.J., Mediation analyses: applications in nutrition research and reading the literature. J. Am. Diet. Assoc. 110 (2010), 753–762, 10.1016/j.jada.2010.02.005.
    • (2010) J. Am. Diet. Assoc. , vol.110 , pp. 753-762
    • Lockwood, C.M.1    DeFrancesco, C.A.2    Elliot, D.L.3    Beresford, S.A.4    Toobert, D.J.5
  • 90
    • 79952858288 scopus 로고    scopus 로고
    • Prenatal famine and adult health
    • Lumey, L.H., Stein, A.D., Susser, E., Prenatal famine and adult health. Annu. Rev. Public Health 32 (2011), 237–262, 10.1146/annurev-publhealth-031210-101230.
    • (2011) Annu. Rev. Public Health , vol.32 , pp. 237-262
    • Lumey, L.H.1    Stein, A.D.2    Susser, E.3
  • 91
    • 84949979279 scopus 로고    scopus 로고
    • Sex-specific effects of prenatal stress on bdnf expression in response to an acute challenge in rats: a role for gadd45beta
    • Luoni, A., Berry, A., Raggi, C., Bellisario, V., Cirulli, F., Riva, M.A., Sex-specific effects of prenatal stress on bdnf expression in response to an acute challenge in rats: a role for gadd45beta. Mol. Neurobiol. 53 (2016), 7037–7047, 10.1007/s12035-015-9569-4.
    • (2016) Mol. Neurobiol. , vol.53 , pp. 7037-7047
    • Luoni, A.1    Berry, A.2    Raggi, C.3    Bellisario, V.4    Cirulli, F.5    Riva, M.A.6
  • 93
    • 84858164821 scopus 로고    scopus 로고
    • Placental 11-beta hydroxysteroid dehydrogenase methylation is associated with newborn growth and a measure of neurobehavioral outcome
    • Marsit, C.J., Maccani, M.A., Padbury, J.F., Lester, B.M., Placental 11-beta hydroxysteroid dehydrogenase methylation is associated with newborn growth and a measure of neurobehavioral outcome. PLoS One, 7, 2012, e33794, 10.1371/journal.pone.0033794.
    • (2012) PLoS One , vol.7 , pp. e33794
    • Marsit, C.J.1    Maccani, M.A.2    Padbury, J.F.3    Lester, B.M.4
  • 94
    • 33645953010 scopus 로고    scopus 로고
    • Fetal programming: causes and consequences as revealed by studies of dietary manipulation in rates − a review
    • McArdle, H.J., Andersen, H.S., Jones, H., Gambling, L., Fetal programming: causes and consequences as revealed by studies of dietary manipulation in rates − a review. Placenta 27 (2006), S56–S60.
    • (2006) Placenta , vol.27 , pp. S56-S60
    • McArdle, H.J.1    Andersen, H.S.2    Jones, H.3    Gambling, L.4
  • 95
  • 96
    • 84929504855 scopus 로고    scopus 로고
    • Ancestral experience as a game changer in stress vulnerability and disease outcomes
    • Metz, G.A.S., Ancestral experience as a game changer in stress vulnerability and disease outcomes. Bioessays 37 (2015), 602–611.
    • (2015) Bioessays , vol.37 , pp. 602-611
    • Metz, G.A.S.1
  • 97
    • 84874338943 scopus 로고    scopus 로고
    • Epigenetic memory in mammals
    • Migicovsky, Z., Kovalchuk, I., Epigenetic memory in mammals. Front. Genet., 2, 2011, 28, 10.3389/fgene.2011.00028.
    • (2011) Front. Genet. , vol.2 , pp. 28
    • Migicovsky, Z.1    Kovalchuk, I.2
  • 98
    • 84903218041 scopus 로고    scopus 로고
    • Glucocorticoids and fetal programming part 2: Mechanisms
    • Moisiadis, V.G., Matthews, S.G., Glucocorticoids and fetal programming part 2: Mechanisms. Nat. Rev. Endocrinol. 10 (2014), 403–411, 10.1038/nrendo.2014.74.
    • (2014) Nat. Rev. Endocrinol. , vol.10 , pp. 403-411
    • Moisiadis, V.G.1    Matthews, S.G.2
  • 99
    • 84991262656 scopus 로고    scopus 로고
    • Distress during pregnancy: epigenetic regulation of placenta glucocorticoid-related genes and fetal neurobehavior
    • Monk, C., Feng, T., Lee, S., Krupska, I., Champagne, F.A., Tycko, B., Distress during pregnancy: epigenetic regulation of placenta glucocorticoid-related genes and fetal neurobehavior. Am. J. Psychiatry 173 (2016), 705–713, 10.1176/appi.ajp.2015.15091171.
    • (2016) Am. J. Psychiatry , vol.173 , pp. 705-713
    • Monk, C.1    Feng, T.2    Lee, S.3    Krupska, I.4    Champagne, F.A.5    Tycko, B.6
  • 100
    • 80051724610 scopus 로고    scopus 로고
    • Early prenatal stress epigenetically programs dysmasculinization in second-generation offspring via the paternal lineage
    • Morgan, C.P., Bale, T.L., Early prenatal stress epigenetically programs dysmasculinization in second-generation offspring via the paternal lineage. J. Neurosci. 31 (2011), 11748–11755, 10.1523/JNEUROSCI.1887–11.2011.
    • (2011) J. Neurosci. , vol.31 , pp. 11748-11755
    • Morgan, C.P.1    Bale, T.L.2
  • 102
    • 54049086269 scopus 로고    scopus 로고
    • Sex-specific programming of offspring emotionality after stress early in pregnancy
    • Mueller, B.R., Bale, T.L., Sex-specific programming of offspring emotionality after stress early in pregnancy. J. Neurosci. 28 (2008), 9055–9065.
    • (2008) J. Neurosci. , vol.28 , pp. 9055-9065
    • Mueller, B.R.1    Bale, T.L.2
  • 103
    • 84864723143 scopus 로고    scopus 로고
    • Methylation changes at NR3C1 in newborns associate with maternal prenatal stress exposure and newborn birth weight
    • Mulligan, C., D'Errico, N., Stees, J., Hughes, D., Methylation changes at NR3C1 in newborns associate with maternal prenatal stress exposure and newborn birth weight. Epigenetics, 7, 2012.
    • (2012) Epigenetics , vol.7
    • Mulligan, C.1    D'Errico, N.2    Stees, J.3    Hughes, D.4
  • 104
    • 84928883695 scopus 로고    scopus 로고
    • Effects of prenatal and postnatal depression, and maternal stroking, at the glucocorticoid receptor gene
    • Murgatroyd, C., Quinn, J.P., Sharp, H.M., Pickles, A., Hill, J., Effects of prenatal and postnatal depression, and maternal stroking, at the glucocorticoid receptor gene. Transl. Psychiatry, 5, 2015, e560, 10.1038/tp.2014.140.
    • (2015) Transl. Psychiatry , vol.5 , pp. e560
    • Murgatroyd, C.1    Quinn, J.P.2    Sharp, H.M.3    Pickles, A.4    Hill, J.5
  • 105
    • 0036016617 scopus 로고    scopus 로고
    • Reduced 11beta-hydroxysteroid dehydrogenase type 2 activity is associated with decreased birth weight centile in pregnancies complicated by asthma
    • Murphy, V.E., Zakar, T., Smith, R., Giles, W.B., Gibson, P.G., Clifton, V.L., Reduced 11beta-hydroxysteroid dehydrogenase type 2 activity is associated with decreased birth weight centile in pregnancies complicated by asthma. J. Clin. Endocrinol. Metab. 87 (2002), 1660–1668, 10.1210/jcem.87.4.8377.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 1660-1668
    • Murphy, V.E.1    Zakar, T.2    Smith, R.3    Giles, W.B.4    Gibson, P.G.5    Clifton, V.L.6
  • 106
    • 84859101516 scopus 로고    scopus 로고
    • Prenatal stress produces sexually dimorphic and regionally specific changes in gene expression in hippocampus and frontal cortex of developing rat offspring
    • Mychasiuk, R., Gibb, R., Kolb, B., Prenatal stress produces sexually dimorphic and regionally specific changes in gene expression in hippocampus and frontal cortex of developing rat offspring. Dev. Neurosci. 33 (2011), 531–538, 10.1159/000335524.
    • (2011) Dev. Neurosci. , vol.33 , pp. 531-538
    • Mychasiuk, R.1    Gibb, R.2    Kolb, B.3
  • 107
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex [see comments]
    • Nan, X., Ng, H.H., Johnson, C.A., Laherty, C.D., Turner, B.M., Eisenman, R.N., Bird, A., Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex [see comments]. Nature 393 (1998), 386–389.
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1    Ng, H.H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6    Bird, A.7
  • 108
    • 0037701826 scopus 로고    scopus 로고
    • Proopiomelanocortin gene expression and DNA methylation: implications for Cushing's syndrome and beyond
    • Newell-Price, J., Proopiomelanocortin gene expression and DNA methylation: implications for Cushing's syndrome and beyond. J. Endocrinol. 177 (2003), 365–372.
    • (2003) J. Endocrinol. , vol.177 , pp. 365-372
    • Newell-Price, J.1
  • 109
    • 42949100803 scopus 로고    scopus 로고
    • The hypothalamic-pituitary-adrenal-axis in the regulation of energy balance
    • Nieuwenhuizen, A.G., Rutters, F., The hypothalamic-pituitary-adrenal-axis in the regulation of energy balance. Physiol. Behav. 94 (2008), 169–177, 10.1016/j.physbeh.2007.12.011.
    • (2008) Physiol. Behav. , vol.94 , pp. 169-177
    • Nieuwenhuizen, A.G.1    Rutters, F.2
  • 110
    • 0032524014 scopus 로고    scopus 로고
    • Glucocorticoid exposure in late gestation permanently programs rat hepatic phosphoenolpyruvate carboxykinase and glucocorticoid receptor expression and causes glucose intolerance in adult offspring
    • Nyirenda, M.J., Lindsay, R.S., Kenyon, C.J., Burchell, A., Seckl, J.R., Glucocorticoid exposure in late gestation permanently programs rat hepatic phosphoenolpyruvate carboxykinase and glucocorticoid receptor expression and causes glucose intolerance in adult offspring. J. Clin. Invest. 101 (1998), 2174–2181, 10.1172/JCI1567.
    • (1998) J. Clin. Invest. , vol.101 , pp. 2174-2181
    • Nyirenda, M.J.1    Lindsay, R.S.2    Kenyon, C.J.3    Burchell, A.4    Seckl, J.R.5
  • 111
    • 0036260295 scopus 로고    scopus 로고
    • Maternal antenatal anxiety and children's behavioural/emotional problems at 4 years
    • O'Connor, T.G., Heron, J., Golding, J., Beveridge, M., Glover, V., Maternal antenatal anxiety and children's behavioural/emotional problems at 4 years. Br. J. Psychiatry 180 (2002), 502–508.
    • (2002) Br. J. Psychiatry , vol.180 , pp. 502-508
    • O'Connor, T.G.1    Heron, J.2    Golding, J.3    Beveridge, M.4    Glover, V.5
  • 112
    • 0141887058 scopus 로고    scopus 로고
    • Maternal antenatal anxiety and behavioural/emtional problems in children: a test of a programming hypothesis
    • O'Connor, T.G., Heron, J., Golding, J., Glover, V., Team, A.S., Maternal antenatal anxiety and behavioural/emtional problems in children: a test of a programming hypothesis. J. Child Psychol. Psychiatry 44 (2003), 1025–1036.
    • (2003) J. Child Psychol. Psychiatry , vol.44 , pp. 1025-1036
    • O'Connor, T.G.1    Heron, J.2    Golding, J.3    Glover, V.4    Team, A.S.5
  • 113
    • 85016926246 scopus 로고    scopus 로고
    • Fetal origins of mental health: the developmental origins of health and disease hypothesis
    • appiajp201616020138
    • O'Donnell, K.J., Meaney, M.J., Fetal origins of mental health: the developmental origins of health and disease hypothesis. Am. J. Psychiatry, 2016, 10.1176/appi.ajp.2016.16020138 appiajp201616020138.
    • (2016) Am. J. Psychiatry
    • O'Donnell, K.J.1    Meaney, M.J.2
  • 114
    • 37249031342 scopus 로고    scopus 로고
    • Infant serotonin transporter (SLC6A4) promoter genotype is associated with adverse neonatal outcomes after prenatal exposure to serotonin reuptake inhibitor medications
    • Oberlander, T.F., Bonaguro, R.J., Misri, S., Papsdorf, M., Ross, C.J., Simpson, E.M., Infant serotonin transporter (SLC6A4) promoter genotype is associated with adverse neonatal outcomes after prenatal exposure to serotonin reuptake inhibitor medications. Mol. Psychiatry 13 (2008), 65–73.
    • (2008) Mol. Psychiatry , vol.13 , pp. 65-73
    • Oberlander, T.F.1    Bonaguro, R.J.2    Misri, S.3    Papsdorf, M.4    Ross, C.J.5    Simpson, E.M.6
  • 115
    • 47149100122 scopus 로고    scopus 로고
    • Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses
    • Oberlander, T.F., Weinberg, J., Papsdorf, M., Grunau, R., Misri, S., Devlin, A.M., Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics 3 (2008), 97–106, 10.4161/epi.3.2.6034.
    • (2008) Epigenetics , vol.3 , pp. 97-106
    • Oberlander, T.F.1    Weinberg, J.2    Papsdorf, M.3    Grunau, R.4    Misri, S.5    Devlin, A.M.6
  • 116
    • 0142186764 scopus 로고    scopus 로고
    • Fetal origins of obesity
    • Oken, E., Gillman, M.W., Fetal origins of obesity. Obes. Res. 11 (2003), 496–506.
    • (2003) Obes. Res. , vol.11 , pp. 496-506
    • Oken, E.1    Gillman, M.W.2
  • 117
    • 84978646614 scopus 로고    scopus 로고
    • Prenatal stress fearfulness, and the epigenome: exploratory analysis of sex differences in DNA methylation of the glucocorticoid receptor gene
    • Ostlund, B.D., Conradt, E., Crowell, S.E., Tyrka, A.R., Marsit, C.J., Lester, B.M., Prenatal stress fearfulness, and the epigenome: exploratory analysis of sex differences in DNA methylation of the glucocorticoid receptor gene. Front. Behav. Neurosci., 10, 2016, 147, 10.3389/fnbeh.2016.00147.
    • (2016) Front. Behav. Neurosci. , vol.10 , pp. 147
    • Ostlund, B.D.1    Conradt, E.2    Crowell, S.E.3    Tyrka, A.R.4    Marsit, C.J.5    Lester, B.M.6
  • 119
    • 0041765653 scopus 로고    scopus 로고
    • How stress influences the immune response
    • Padgett, D.A., Glaser, R., How stress influences the immune response. Trends Immunol. 24 (2003), 444–448.
    • (2003) Trends Immunol. , vol.24 , pp. 444-448
    • Padgett, D.A.1    Glaser, R.2
  • 120
    • 49649092218 scopus 로고    scopus 로고
    • Transgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later life
    • Painter, R.C., Osmond, C., Gluckman, P., Hanson, M., Phillips, D.I., Roseboom, T.J., Transgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later life. BJOG 115 (2008), 1243–1249, 10.1111/j.1471-0528.2008.01822.x.
    • (2008) BJOG , vol.115 , pp. 1243-1249
    • Painter, R.C.1    Osmond, C.2    Gluckman, P.3    Hanson, M.4    Phillips, D.I.5    Roseboom, T.J.6
  • 122
    • 84905851457 scopus 로고    scopus 로고
    • Placental FKBP5 genetic and epigenetic variation is associated with infant neurobehavioral outcomes in the RICHS cohort
    • Paquette, A.G., Lester, B.M., Koestler, D.C., Lesseur, C., Armstrong, D.A., Marsit, C.J., Placental FKBP5 genetic and epigenetic variation is associated with infant neurobehavioral outcomes in the RICHS cohort. PLoS One, 9, 2014, e104913, 10.1371/journal.pone.0104913.
    • (2014) PLoS One , vol.9 , pp. e104913
    • Paquette, A.G.1    Lester, B.M.2    Koestler, D.C.3    Lesseur, C.4    Armstrong, D.A.5    Marsit, C.J.6
  • 125
    • 80053979591 scopus 로고    scopus 로고
    • Maternal depression and anxiety are associated with altered gene expression in the human placenta without modification by antidepressant use: implications for fetal programming
    • Ponder, K.L., Salisbury, A., McGonnigal, B., Laliberte, A., Lester, B., Padbury, J.F., Maternal depression and anxiety are associated with altered gene expression in the human placenta without modification by antidepressant use: implications for fetal programming. Dev. Psychobiol. 53 (2011), 711–723, 10.1002/dev.20549.
    • (2011) Dev. Psychobiol. , vol.53 , pp. 711-723
    • Ponder, K.L.1    Salisbury, A.2    McGonnigal, B.3    Laliberte, A.4    Lester, B.5    Padbury, J.F.6
  • 126
    • 84984780842 scopus 로고    scopus 로고
    • SLC6A4 methylation as an epigenetic marker of life adversity exposures in humans: a systematic review of literature
    • Provenzi, L., Giorda, R., Beri, S., Montirosso, R., SLC6A4 methylation as an epigenetic marker of life adversity exposures in humans: a systematic review of literature. Neurosci. Biobehav. Rev. 71 (2016), 7–20, 10.1016/j.neubiorev.2016.08.021.
    • (2016) Neurosci. Biobehav. Rev. , vol.71 , pp. 7-20
    • Provenzi, L.1    Giorda, R.2    Beri, S.3    Montirosso, R.4
  • 127
    • 79960649740 scopus 로고    scopus 로고
    • Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor
    • Radtke, K.M., Ruf, M., Gunter, H.M., Dohrmann, K., Schauer, M., Meyer, A., Elbert, T., Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor. Transl. Psychiatry, 1, 2011, e21, 10.1038/tp.2011.21.
    • (2011) Transl. Psychiatry , vol.1 , pp. e21
    • Radtke, K.M.1    Ruf, M.2    Gunter, H.M.3    Dohrmann, K.4    Schauer, M.5    Meyer, A.6    Elbert, T.7
  • 129
    • 0021168535 scopus 로고
    • DNA methylation patterns: formation and function
    • Razin, A., Szyf, M., DNA methylation patterns: formation and function. Biochim. Biophys. Acta 782 (1984), 331–342.
    • (1984) Biochim. Biophys. Acta , vol.782 , pp. 331-342
    • Razin, A.1    Szyf, M.2
  • 132
    • 80052572090 scopus 로고    scopus 로고
    • Hungry in the womb: what are the consequences? Lessons from the Dutch famine
    • Roseboom, T.J., Painter, R.C., van Abeelen, A.F., Veenendaal, M.V., de Rooij, S.R., Hungry in the womb: what are the consequences? Lessons from the Dutch famine. Maturitas 70 (2011), 141–145, 10.1016/j.maturitas.2011.06.017.
    • (2011) Maturitas , vol.70 , pp. 141-145
    • Roseboom, T.J.1    Painter, R.C.2    van Abeelen, A.F.3    Veenendaal, M.V.4    de Rooij, S.R.5
  • 133
    • 84943594609 scopus 로고    scopus 로고
    • Sex-Specific placental responses in fetal development
    • Rosenfeld, C.S., Sex-Specific placental responses in fetal development. Endocrinology 156 (2015), 3422–3434, 10.1210/en.2015-1227.
    • (2015) Endocrinology , vol.156 , pp. 3422-3434
    • Rosenfeld, C.S.1
  • 134
    • 0033085618 scopus 로고    scopus 로고
    • The measurement of stress in pregnancy
    • Ruiz, R.J., Fullerton, J.T., The measurement of stress in pregnancy. Nurs. Health Sci. 1 (1999), 19–25.
    • (1999) Nurs. Health Sci. , vol.1 , pp. 19-25
    • Ruiz, R.J.1    Fullerton, J.T.2
  • 136
    • 33646775989 scopus 로고    scopus 로고
    • Elevated maternal cortisol early in pregnancy predicts third trimester levels of placental corticotropin releasing hormone (CRH): priming the placental clock
    • Sandman, C.A., Glynn, L., Schetter, C.D., Wadhwa, P., Garite, T., Chicz-DeMet, A., Hobel, C., Elevated maternal cortisol early in pregnancy predicts third trimester levels of placental corticotropin releasing hormone (CRH): priming the placental clock. Peptides 27 (2006), 1457–1463, 10.1016/j.peptides.2005.10.002.
    • (2006) Peptides , vol.27 , pp. 1457-1463
    • Sandman, C.A.1    Glynn, L.2    Schetter, C.D.3    Wadhwa, P.4    Garite, T.5    Chicz-DeMet, A.6    Hobel, C.7
  • 137
    • 33745603236 scopus 로고    scopus 로고
    • Maternal anxiety at amniocentesis and plasma cortisol
    • Sarkar, P., Bergman, K., Fisk, N.M., Glover, V., Maternal anxiety at amniocentesis and plasma cortisol. Prenat. Diagn. 26 (2006), 505–509, 10.1002/pd.1444.
    • (2006) Prenat. Diagn. , vol.26 , pp. 505-509
    • Sarkar, P.1    Bergman, K.2    Fisk, N.M.3    Glover, V.4
  • 138
    • 0000178642 scopus 로고    scopus 로고
    • Effect of prenatal stress on development: a nonhuman primate model
    • C. Nelson Lawrence Erlbaum Hillsdale, NJ
    • Schneider, M.L., Moore, C.F., Effect of prenatal stress on development: a nonhuman primate model. Nelson, C., (eds.) Minnesota Symposium on Child Psychology, 2000, Lawrence Erlbaum, Hillsdale, NJ, 201–243.
    • (2000) Minnesota Symposium on Child Psychology , pp. 201-243
    • Schneider, M.L.1    Moore, C.F.2
  • 139
    • 0031588509 scopus 로고    scopus 로고
    • Understanding human parturition
    • Schwartz, L.B., Understanding human parturition. Lancet 350 (1997), 1792–1793, 10.1016/S0140-6736(05)63632-X.
    • (1997) Lancet , vol.350 , pp. 1792-1793
    • Schwartz, L.B.1
  • 140
    • 34249316880 scopus 로고    scopus 로고
    • Mechanisms of disease: glucocorticoids, their placental metabolism and fetal ‘programming' of adult pathophysiology. Nature Clinical Practice
    • Seckl, J.R., Holmes, M.C., Mechanisms of disease: glucocorticoids, their placental metabolism and fetal ‘programming' of adult pathophysiology. Nature Clinical Practice. Endocrinol. Metab. 3 (2007), 479–488, 10.1038/ncpendmet0515.
    • (2007) Endocrinol. Metab. , vol.3 , pp. 479-488
    • Seckl, J.R.1    Holmes, M.C.2
  • 141
    • 36248940166 scopus 로고    scopus 로고
    • Glucocorticoids, developmental ‘programming' and the risk of affective dysfunction
    • Seckl, J.R., Glucocorticoids, developmental ‘programming' and the risk of affective dysfunction. Prog. Brain Res. 167 (2008), 17–34, 10.1016/S0079-6123(07)67002-2.
    • (2008) Prog. Brain Res. , vol.167 , pp. 17-34
    • Seckl, J.R.1
  • 142
    • 84971473615 scopus 로고    scopus 로고
    • Long-term effects of early life stress exposure: role of epigenetic mechanisms
    • Silberman, D.M., Acosta, G.B., Zorrilla Zubilete, M.A., Long-term effects of early life stress exposure: role of epigenetic mechanisms. Pharmacol. Res. 109 (2016), 64–73, 10.1016/j.phrs.2015.12.033.
    • (2016) Pharmacol. Res. , vol.109 , pp. 64-73
    • Silberman, D.M.1    Acosta, G.B.2    Zorrilla Zubilete, M.A.3
  • 143
    • 78649455759 scopus 로고    scopus 로고
    • Environmental signals and transgenerational epigenetics
    • Skinner, M.K., Guerrero-Bosagna, C., Environmental signals and transgenerational epigenetics. Epigenomics 1 (2009), 111–117, 10.2217/epi.09.11.
    • (2009) Epigenomics , vol.1 , pp. 111-117
    • Skinner, M.K.1    Guerrero-Bosagna, C.2
  • 144
    • 56749170156 scopus 로고    scopus 로고
    • Transgenerational epigenetic programming of the brain transcriptome and anxiety behavior
    • Skinner, M.K., Anway, M.D., Savenkova, M.I., Gore, A.C., Crews, D., Transgenerational epigenetic programming of the brain transcriptome and anxiety behavior. PLoS One, 3, 2008, e3745, 10.1371/journal.pone.0003745.
    • (2008) PLoS One , vol.3 , pp. e3745
    • Skinner, M.K.1    Anway, M.D.2    Savenkova, M.I.3    Gore, A.C.4    Crews, D.5
  • 145
    • 37349004800 scopus 로고    scopus 로고
    • What is an epigenetic transgenerational phenotype? F3 or F2
    • Skinner, M.K., What is an epigenetic transgenerational phenotype? F3 or F2. Reprod. Toxicol. 25 (2008), 2–6, 10.1016/j.reprotox.2007.09.001.
    • (2008) Reprod. Toxicol. , vol.25 , pp. 2-6
    • Skinner, M.K.1
  • 146
    • 33845295829 scopus 로고    scopus 로고
    • Hyperactivity and alteration of the midbrain dopaminergic system in maternally stressed male mice offsrping
    • Son, G.H., Chung, S., Geum, D., Kang, S.S., Choi, W.S., Kim, K., Choi, S., Hyperactivity and alteration of the midbrain dopaminergic system in maternally stressed male mice offsrping. Biochem. Biophys. Res. Commun. 352 (2007), 823–829.
    • (2007) Biochem. Biophys. Res. Commun. , vol.352 , pp. 823-829
    • Son, G.H.1    Chung, S.2    Geum, D.3    Kang, S.S.4    Choi, W.S.5    Kim, K.6    Choi, S.7
  • 148
    • 65249157050 scopus 로고    scopus 로고
    • Epigenetics, DNA methylation, and chromatin modifying drugs
    • Szyf, M., Epigenetics, DNA methylation, and chromatin modifying drugs. Annu. Rev. Pharmacool. Toxicol., 49, 2009.
    • (2009) Annu. Rev. Pharmacool. Toxicol. , vol.49
    • Szyf, M.1
  • 149
    • 0035901508 scopus 로고    scopus 로고
    • Glucocorticoid-induced DNA demethylation and gene memory during development
    • Thomassin, H., Flavin, M., Espinas, M.L., Grange, T., Glucocorticoid-induced DNA demethylation and gene memory during development. EMBO J. 20 (2001), 1974–1983.
    • (2001) EMBO J. , vol.20 , pp. 1974-1983
    • Thomassin, H.1    Flavin, M.2    Espinas, M.L.3    Grange, T.4
  • 151
    • 84861605111 scopus 로고    scopus 로고
    • Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19
    • Tobi, E.W., Slagboom, P.E., van Dongen, J., Kremer, D., Stein, A.D., Putter, H., Heijmans, B.T., Lumey, L.H., Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19. PLoS One, 7, 2012, e37933, 10.1371/journal.pone.0037933.
    • (2012) PLoS One , vol.7 , pp. e37933
    • Tobi, E.W.1    Slagboom, P.E.2    van Dongen, J.3    Kremer, D.4    Stein, A.D.5    Putter, H.6    Heijmans, B.T.7    Lumey, L.H.8
  • 153
    • 84930814243 scopus 로고    scopus 로고
    • Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome
    • Tobi, E.W., Slieker, R.C., Stein, A.D., Suchiman, H.E., Slagboom, P.E., van Zwet, E.W., Heijmans, B.T., Lumey, L.H., Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome. Int. J. Epidemiol. 44 (2015), 1211–1223, 10.1093/ije/dyv043.
    • (2015) Int. J. Epidemiol. , vol.44 , pp. 1211-1223
    • Tobi, E.W.1    Slieker, R.C.2    Stein, A.D.3    Suchiman, H.E.4    Slagboom, P.E.5    van Zwet, E.W.6    Heijmans, B.T.7    Lumey, L.H.8
  • 154
    • 84951569507 scopus 로고    scopus 로고
    • Effects of the social environment and stress on glucocorticoid receptor gene methylation: a systematic review
    • Turecki, G., Meaney, M.J., Effects of the social environment and stress on glucocorticoid receptor gene methylation: a systematic review. Biol. Psychiatry 79 (2016), 87–96, 10.1016/j.biopsych.2014.11.022.
    • (2016) Biol. Psychiatry , vol.79 , pp. 87-96
    • Turecki, G.1    Meaney, M.J.2
  • 157
    • 84894427083 scopus 로고    scopus 로고
    • Prenatal maternal stress exposure and immune function in the offspring
    • Veru, F., Laplante, D.P., Luheshi, G., King, S., Prenatal maternal stress exposure and immune function in the offspring. Stress 17 (2014), 133–148, 10.3109/10253890.2013.876404.
    • (2014) Stress , vol.17 , pp. 133-148
    • Veru, F.1    Laplante, D.P.2    Luheshi, G.3    King, S.4
  • 158
    • 84894427083 scopus 로고    scopus 로고
    • Prenatal maternal stress exposure and immune function in the offspring
    • Veru, F., Laplante, D.P., Luheshi, G., King, S., Prenatal maternal stress exposure and immune function in the offspring. Stress 17 (2014), 133–148, 10.3109/10253890.2013.876404.
    • (2014) Stress , vol.17 , pp. 133-148
    • Veru, F.1    Laplante, D.P.2    Luheshi, G.3    King, S.4
  • 160
    • 84897489039 scopus 로고    scopus 로고
    • The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts
    • Wagner, J.R., Busche, S., Ge, B., Kwan, T., Pastinen, T., Blanchette, M., The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts. Genome Biol., 15, 2014, R37, 10.1186/gb-2014-15-2-r37.
    • (2014) Genome Biol. , vol.15 , pp. R37
    • Wagner, J.R.1    Busche, S.2    Ge, B.3    Kwan, T.4    Pastinen, T.5    Blanchette, M.6
  • 161
    • 84902774378 scopus 로고    scopus 로고
    • Effects of genetic and early environmental risk factors for depression on serotonin transporter expression and methylation profiles
    • Wankerl, M., Miller, R., Kirschbaum, C., Hennig, J., Stalder, T., Alexander, N., Effects of genetic and early environmental risk factors for depression on serotonin transporter expression and methylation profiles. Transl. Psychiatry, 4, 2014, e402, 10.1038/tp.2014.37.
    • (2014) Transl. Psychiatry , vol.4 , pp. e402
    • Wankerl, M.1    Miller, R.2    Kirschbaum, C.3    Hennig, J.4    Stalder, T.5    Alexander, N.6
  • 163
    • 0034749488 scopus 로고    scopus 로고
    • Alterations induced by gestational stress in brain morphology and behaviour of the offspring
    • Weinstock, M., Alterations induced by gestational stress in brain morphology and behaviour of the offspring. Prog. Neurobiol. 65 (2001), 427–451.
    • (2001) Prog. Neurobiol. , vol.65 , pp. 427-451
    • Weinstock, M.1
  • 164
    • 45849128326 scopus 로고    scopus 로고
    • The long-term behavioural consequences of prenatal stress
    • Weinstock, M., The long-term behavioural consequences of prenatal stress. Neurosci. Biobehav. Rev. 32 (2008), 1073–1086.
    • (2008) Neurosci. Biobehav. Rev. , vol.32 , pp. 1073-1086
    • Weinstock, M.1
  • 165
    • 0035180462 scopus 로고    scopus 로고
    • Prenatal stress, glucocorticoids and the programming of the brain
    • Welberg, L.A.M., Seckl, J.R., Prenatal stress, glucocorticoids and the programming of the brain. J. Neuroendocrinol. 13 (2001), 113–128.
    • (2001) J. Neuroendocrinol. , vol.13 , pp. 113-128
    • Welberg, L.A.M.1    Seckl, J.R.2
  • 168
    • 84905911703 scopus 로고    scopus 로고
    • Ancestral exposure to stress epigenetically programs preterm birth risk and adverse maternal and newborn outcomes
    • Yao, Y., Robinson, A.M., Zucchi, F.C., Robbins, J.C., Babenko, O., Kovalchuk, O., Kovalchuk, I., Olson, D.M., Metz, G.A., Ancestral exposure to stress epigenetically programs preterm birth risk and adverse maternal and newborn outcomes. BMC Med. 12 (2014), 1–12, 10.1186/s12916-014-0121-6.
    • (2014) BMC Med. , vol.12 , pp. 1-12
    • Yao, Y.1    Robinson, A.M.2    Zucchi, F.C.3    Robbins, J.C.4    Babenko, O.5    Kovalchuk, O.6    Kovalchuk, I.7    Olson, D.M.8    Metz, G.A.9
  • 169
    • 84869090771 scopus 로고    scopus 로고
    • Epigenetic mechanisms for the early environmental regulation of hippocampal glucocorticoid receptor gene expression in rodents and humans
    • Zhang, T.Y., Labonte, B., Wen, X.L., Turecki, G., Meaney, M.J., Epigenetic mechanisms for the early environmental regulation of hippocampal glucocorticoid receptor gene expression in rodents and humans. Neuropsychopharmacology 38 (2013), 111–123, 10.1038/npp.2012.149.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 111-123
    • Zhang, T.Y.1    Labonte, B.2    Wen, X.L.3    Turecki, G.4    Meaney, M.J.5
  • 170
    • 84874323462 scopus 로고    scopus 로고
    • The secret language of destiny: stress imprinting and transgenerational origins of disease
    • Zucchi, F.C., Yao, Y., Metz, G.A., The secret language of destiny: stress imprinting and transgenerational origins of disease. Front. Genet., 3, 2012, 96, 10.3389/fgene.2012.00096.
    • (2012) Front. Genet. , vol.3 , pp. 96
    • Zucchi, F.C.1    Yao, Y.2    Metz, G.A.3


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