How stress influences the immune response

Trends in Immunology

Volumn 24, Issue 8, 2003, Pages 444-448

  Padgett, David A ^a   Glaser, Ronald ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ADRENERGIC RECEPTOR; BINDING PROTEIN; CATECHOLAMINE; CYCLIC AMP; CYTOKINE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NORADRENALIN;

ADRENAL MEDULLA; ADRENERGIC SYSTEM; CYTOKINE PRODUCTION; GENETIC CODE; HORMONE SYNTHESIS; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNE FUNCTION TEST; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; NONHUMAN; REVIEW; STRESS;

EID: 0041765653     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4906(03)00173-X     Document Type: Review

References (55)

1. Rabin B.S. Stress, Immune Function, and Health: The Connection. 1999;Wiley-Liss & Sons.
2. Madden K.S., Livnat S. Catecholamine action and immunologic reactivity. Ader R., et al. Psychoneuroimmunology. 2nd edn:1991;Academic Press.
3. Elenkov I., et al. Modulatory effects of glucocorticoids and catecholamines on human interleukin-12 and interleukin-10 production: clinical implications. Proc. Assoc. Am. Physicians. 108:1996;374-381.
4. Marshall G.D. Jr, et al. Cytokine dysregulation associated with exam stress in healthy medical students. Brain Behav. Immun. 12:1998;297-307.
5. Glaser R., et al. Evidence for a shift in the Th-1 to Th-2 cytokine response associated with chronic stress and aging. J. Gerontol. A Biol. Sci. Med. Sci. 56:2001;M477-M482.
6. Glaser R., et al. Stress-induced modulation of the immune response to recombinant hepatitis B vaccine. Psychosom. Med. 54:1992;22-29.
7. Kiecolt-Glaser J.K., et al. Chronic stress alters the immune response to influenza virus vaccine in older adults. Proc. Natl. Acad. Sci. U. S. A. 93:1996;3043-3047.
8. Glaser R., et al. Chronic stress modulates the immune response to a pneumococcal pneumonia vaccine. Psychosom. Med. 62:2000;804-807.
9. Morag M., et al. Psychological variables as predictors of rubella antibody titers and fatigue-A prospective, double blind study. J. Psychiatr. Res. 33:1999;389-395.
10. Vedhara K., et al. Chronic stress in elderly carers of dementia patients and antibody response to influenza vaccination. Lancet. 353:1999;627-631.
11. Jabaaij L., et al. Modulation of immune response to rDNA Hepatitis B vaccination by psychological stress. J. Psychosom. Res. 41:1996;129-137.
12. Burns E.A., Goodwin J.S. Immunology and infectious disease. Cassel C.K., et al. Geriatric Medicine. 1990;312-329 Springer-Verlag.
13. Patriarca P.A. A randomized controlled trial of influenza vaccine in the elderly. JAMA. 272:1994;1700-1701.
14. Cohen S., et al. Psychological stress and susceptibility to the common cold. N. Engl. J. Med. 325:1991;606-612.
15. McCabe P.M., et al. Animal models of disease. Physiol. Behav. 68:2000;501-507.
16. Padgett D.A., et al. Restraint stress slows cutaneous wound healing in mice. Brain Behav. Immun. 12:1998;64-73.
17. Teunis M.A., et al. Maternal deprivation of rat pups increases clinical symptoms of experimental autoimmune encephalomyelitis at adult age. J. Neuroimmunol. 133:2002;30-38.
18. Dowdell K.C., et al. Neuroendocrine modulation of chronic relapsing experimental autoimmune encephalomyelitis: a critical role for the hypothalamic-pituitary-adrenal axis. J. Neuroimmunol. 100:1999;243-251.
19. Selye H. A syndrome produced by diverse nocuous agents. (Lond). Nature. 138:1936;32.
20. Selye H. Thymus and adrenals in the response of the organism to injuries and intoxication. Br. J. Exp. Pathol. 17:1936;234.
21. Elenkov I.J., Chrousos G.P. Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity. Ann. N. Y. Acad. Sci. 966:2002;290-303.
22. Ashwell J.D., et al. Glucocorticoids in T cell development and function. Annu. Rev. Immunol. 18:1992;309-345.
23. Russo-Marie F. Macrophages and the glucocorticoids. J. Neuroimmunol. 40:1992;281-286.
24. Muller M., et al. Genetic modification of corticosteroid receptor signalling: novel insights into pathophysiology and treatment strategies of human affective disorders. Neuropeptides. 36:2002;117-131.
25. DeRijk R.H., et al. Glucocorticoid receptor variants: clinical implications. J. Steroid Biochem. Mol. Biol. 81:2002;103-122.
26. Marchetti B., et al. Stress, the immune system and vulnerability to degenerative disorders of the central nervous system in transgenic mice expressing glucocorticoid receptor antisense RNA. Brain Res. Brain Res. Rev. 37:2001;259-272.
27. Hoeck W., Groner B. Hormone-dependent phosphorylation of the glucocorticoid receptor occurs mainly in the amino-terminal transactivation domain. J. Biol. Chem. 265:1990;5403-5408.
28. La Baer J., Yamamoto K.R. Analysis of the DNA-binding affinity, sequence specificity and context dependence of the glucocorticoid receptor zinc finger region. J. Mol. Biol. 239:1994;664-688.
29. Kanelakis K.C., et al. Nucleotide binding states of hsp70 and hsp90 during sequential steps in the process of glucocorticoid receptor hsp90 heterocomplex assembly. J. Biol. Chem. 277:2002;33698-33703.
30. Howard K.J., et al. Mapping the HSP90 binding region of the glucocorticoid receptor. J. Biol. Chem. 265:1990;11928-11935.
31. Berg J.M. DNA binding specificity of steroid receptors. Cell. 57:1989;1065-1068.
32. Scheinman R.I., et al. Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science. 270:1995;283-286.
33. Auphan N., et al. Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis. Science. 270:1995;286-289.
34. Li Q., Verma I.M. NF-κB regulation in the immune system. Nat. Rev. Immunol. 2:2002;725-734.
35. Adcock I.M., et al. Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: preferential targetting of NF-κB and lack of I-κB involvement. Br. J. Pharmacol. 127:1999;1003-1011.
36. Wissink S., et al. A dual mechanism mediates repression of NF-κB activity by glucocorticoids. Mol. Endocrinol. 12:1998;355-363.
37. Hofmann T.G., et al. Various glucocorticoids differ in their ability to induce gene expression, apoptosis and to repress NF-κB-dependent transcription. FEBS Lett. 441:1998;441-446.
38. Reichardt H.M., et al. Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor. EMBO J. 20:2001;7168-7173.
39. Adcock I.M., Caramori G. Cross-talk between pro-inflammatory transcription factors and glucocorticoids. Immunol. Cell Biol. 79:2001;376-384.
40. Schaaf M.J., Cidlowski J.A. Molecular mechanisms of glucocorticoid action and resistance. J. Steroid Biochem. Mol. Biol. 83:2002;37-48.
41. Hofmann T.G., Schmitz L.M. The promoter context determines mutual repression or synergism between NF-kappaB and the glucocorticoid receptor. Biol. Chem. 383:2002;1947-1951.
42. De Bosscher K., et al. Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell. Proc. Natl. Acad. Sci. U. S. A. 97:2000;3919-3924.
43. Sheppard K.A., et al. Nuclear integration of glucocorticoid receptor and nuclear factor-κB signaling by CREB-binding protein and steroid receptor coactivator-1. J. Biol. Chem. 273:1998;29291-29294.
44. McKay L.I., Cidlowski J.A. CBP (CREB binding protein) integrates NF-κB (nuclear factor-κB) and glucocorticoid receptor physical interactions and antagonism. Mol. Endocrinol. 14:2000;1222-1234.
45. Sanders V.M., Kohm A.P. Sympathetic nervous system interaction with the immune system. Int. Rev. Neurobiol. 52:2002;17-41.
46. Madden K.S. Catecholamines, sympathetic innervation, and immunity. Brain Behav. Immun. 17:(Suppl 1):2003;5-10.
47. Carrasco G.A., Van de Kar L.D. Neuroendocrine pharmacology of stress. Eur. J. Pharmacol. 463:2003;235-272.
48. Goldfien A. Adrenal medulla. Greenspan F.S., Gardner D.G. Basic and Clinical Endocrinology. 2001;399-421 Lange Medical Books, McGraw-Hill.
49. Felten S.Y., et al. Noradrenergic and peptidergic innervation of lymphoid organs. Chem. Immunol. 52:1992;25-48.
50. Gilman A.G. G proteins: transducers of receptor-generated signals. Annu. Rev. Biochem. 56:1987;615-649.
51. Gardner D.G. Mechanisms of hormone action. Greenspan F.S., Gardner D.G. Basic and Clinical Endocrinology. 2001;59-79 Lange Medical Books, McGraw-Hill.
52. Simonds W.F. G protein regulation of adenylate cyclase. Trends Pharmacol. Sci. 20:1999;66-73.
53. Barradeau S., et al. Intracellular targeting of the type-I α regulatory subunit of cAMP-dependent protein kinase. Trends Cardiovasc. Med. 12:2002;235-241.
54. Vallejo M. Transcriptional control of gene expression by cAMP-response element binding proteins. J. Neuroendocrinol. 6:1994;587-596.
55. Shaywitz A.J., Greenberg M.E. CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu. Rev. Biochem. 68:1999;821-861.