-
1
-
-
61349117970
-
Genetics and epigenetics: Stability and plasticity during cellular differentiation
-
Mohn F, Schübeler D (2009) Genetics and epigenetics: Stability and plasticity during cellular differentiation. Trends Genet 25:129-136.
-
(2009)
Trends Genet
, vol.25
, pp. 129-136
-
-
Mohn, F.1
Schübeler, D.2
-
2
-
-
78049402859
-
Molecular signals of epigenetic states
-
Bonasio R, Tu S, Reinberg D (2010) Molecular signals of epigenetic states. Science 330:612-616.
-
(2010)
Science
, vol.330
, pp. 612-616
-
-
Bonasio, R.1
Tu, S.2
Reinberg, D.3
-
3
-
-
84855956247
-
Epigenetics and the environment: Emerging patterns and implications
-
Feil R, Fraga MF (2011) Epigenetics and the environment: Emerging patterns and implications. Nat Rev Genet 13:97-109.
-
(2011)
Nat Rev Genet
, vol.13
, pp. 97-109
-
-
Feil, R.1
Fraga, M.F.2
-
4
-
-
84858414016
-
Regulated noise in the epigenetic landscape of development and disease
-
Pujadas E, Feinberg AP (2012) Regulated noise in the epigenetic landscape of development and disease. Cell 148:1123-1131.
-
(2012)
Cell
, vol.148
, pp. 1123-1131
-
-
Pujadas, E.1
Feinberg, A.P.2
-
5
-
-
79960556965
-
Epigenome-wide association studies for common human diseases
-
Rakyan VK, Down TA, Balding DJ, Beck S (2011) Epigenome-wide association studies for common human diseases. Nat Rev Genet 12:529-541.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 529-541
-
-
Rakyan, V.K.1
Down, T.A.2
Balding, D.J.3
Beck, S.4
-
6
-
-
3242663659
-
An integrated epigenetic and genetic approach to common human disease
-
DOI 10.1016/j.tig.2004.06.009, PII S016895250400160X
-
Bjornsson HT, Fallin MD, Feinberg AP (2004) An integrated epigenetic and genetic approach to common human disease. Trends Genet 20:350-358. (Pubitemid 38943025)
-
(2004)
Trends in Genetics
, vol.20
, Issue.8
, pp. 350-358
-
-
Bjornsson, H.T.1
Daniele F., M.2
Feinberg, A.P.3
-
7
-
-
35748964705
-
The potential role of epigenomic dysregulation in complex human disease
-
DOI 10.1016/j.tig.2007.08.010, PII S0168952507003022
-
Hatchwell E, Greally JM (2007) The potential role of epigenomic dysregulation in complex human disease. Trends Genet 23:588-595. (Pubitemid 350052352)
-
(2007)
Trends in Genetics
, vol.23
, Issue.11
, pp. 588-595
-
-
Hatchwell, E.1
Greally, J.M.2
-
8
-
-
84858681550
-
Commentary: The seven plagues of epigenetic epidemiology
-
Heijmans BT, Mill J (2012) Commentary: The seven plagues of epigenetic epidemiology. Int J Epidemiol 41:74-78.
-
(2012)
Int J Epidemiol
, vol.41
, pp. 74-78
-
-
Heijmans, B.T.1
Mill, J.2
-
9
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister R, et al. (2009) Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 462:315-322.
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
-
10
-
-
78649969065
-
The DNA methylome of human peripheral blood mononuclear cells
-
Li Y, et al. (2010) The DNA methylome of human peripheral blood mononuclear cells. PLoS Biol 8:e1000533.
-
(2010)
PLoS Biol
, vol.8
-
-
Li, Y.1
-
11
-
-
77249170184
-
Establishing, maintaining and modifying DNA methylation patterns in plants and animals
-
Law JA, Jacobsen SE (2010) Establishing, maintaining and modifying DNA methylation patterns in plants and animals. Nat Rev Genet 11:204-220.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 204-220
-
-
Law, J.A.1
Jacobsen, S.E.2
-
12
-
-
67349255210
-
CpG islands - 'A rough guide'
-
Illingworth RS, Bird AP (2009) CpG islands - 'A rough guide' FEBS Lett 583:1713-1720.
-
(2009)
FEBS Lett
, vol.583
, pp. 1713-1720
-
-
Illingworth, R.S.1
Bird, A.P.2
-
13
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
DOI 10.1038/ng1990, PII NG1990
-
Weber M, et al. (2007) Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 39:457-466. (Pubitemid 46514772)
-
(2007)
Nature Genetics
, vol.39
, Issue.4
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
Ramos, L.4
Paabo, S.5
Rebhan, M.6
Schubeler, D.7
-
14
-
-
0037372003
-
Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
-
DOI 10.1038/ng1089
-
Jaenisch R, Bird A (2003) Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals. Nat Genet 33(Suppl):245-254. (Pubitemid 36278835)
-
(2003)
Nature Genetics
, vol.33
, Issue.SUPPL.
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
15
-
-
40849139208
-
Epigenetics in cancer
-
Esteller M (2008) Epigenetics in cancer. N Engl J Med 358:1148-1159.
-
(2008)
N Engl J Med
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
17
-
-
79960688508
-
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
-
Bell JT, et al. (2011) DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol 12:R10.
-
(2011)
Genome Biol
, vol.12
-
-
Bell, J.T.1
-
18
-
-
70450169678
-
Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns
-
Byun HM, et al. (2009) Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns. Hum Mol Genet 18:4808-4817.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 4808-4817
-
-
Byun, H.M.1
-
19
-
-
33745259517
-
Cell-type specific gene expression profiles of leukocytes in human peripheral blood
-
Palmer C, Diehn M, Alizadeh AA, Brown PO (2006) Cell-type specific gene expression profiles of leukocytes in human peripheral blood. BMC Genomics 7:115.
-
(2006)
BMC Genomics
, vol.7
, pp. 115
-
-
Palmer, C.1
Diehn, M.2
Alizadeh, A.A.3
Brown, P.O.4
-
20
-
-
20144387327
-
Application of genome-wide expression analysis to human health and disease
-
DOI 10.1073/pnas.0409768102
-
Cobb JP, et al.; Inflammation and Host Response to Injury Large-Scale Collaborative Research Program (2005) Application of genome-wide expression analysis to human health and disease. Proc Natl Acad Sci USA 102:4801-4806. (Pubitemid 40471534)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.13
, pp. 4801-4806
-
-
Cobb, J.P.1
Mindrinos, M.N.2
Miller-Graziano, C.3
Calvano, S.E.4
Baker, H.V.5
Xiao, W.6
Laudanski, K.7
Brownstein, B.H.8
Elson, C.M.9
Hayden, D.L.10
Herndon, D.N.11
Lowry, S.F.12
Maier, R.V.13
Schoenfeld, D.A.14
Moldawer, L.L.15
Davis, R.W.16
Tompkins, R.G.17
-
21
-
-
76749090671
-
Epigenetics and the biological definition of gene x environment interactions
-
Meaney MJ (2010) Epigenetics and the biological definition of gene x environment interactions. Child Dev 81:41-79.
-
(2010)
Child Dev
, vol.81
, pp. 41-79
-
-
Meaney, M.J.1
-
22
-
-
33751505540
-
DNA methylation profiling of human chromosomes 6, 20 and 22
-
Eckhardt F, et al. (2006) DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet 38:1378-1385.
-
(2006)
Nat Genet
, vol.38
, pp. 1378-1385
-
-
Eckhardt, F.1
-
23
-
-
84862210732
-
Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood
-
Davies MN, et al. (2012) Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood. Genome Biol 13:R43.
-
(2012)
Genome Biol
, vol.13
-
-
Davies, M.N.1
-
24
-
-
79955594736
-
Child health, developmental plasticity, and epigenetic programming
-
Hochberg Z, et al. (2011) Child health, developmental plasticity, and epigenetic programming. Endocr Rev 32:159-224.
-
(2011)
Endocr Rev
, vol.32
, pp. 159-224
-
-
Hochberg, Z.1
-
25
-
-
77952735964
-
How experience gets under the skin to create gradients in developmental health
-
3p following 347
-
Hertzman C, Boyce T (2010) How experience gets under the skin to create gradients in developmental health. Annu Rev Public Health 31: 329-347, 3p following 347.
-
(2010)
Annu Rev Public Health
, vol.31
, pp. 329-347
-
-
Hertzman, C.1
Boyce, T.2
-
26
-
-
84858657971
-
Associations with early-life socio-economic position in adult DNA methylation
-
Borghol N, et al. (2012) Associations with early-life socio-economic position in adult DNA methylation. Int J Epidemiol 41:62-74.
-
(2012)
Int J Epidemiol
, vol.41
, pp. 62-74
-
-
Borghol, N.1
-
27
-
-
55949137722
-
Persistent epigenetic differences associated with prenatal exposure to famine in humans
-
Heijmans BT, et al. (2008) Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci USA 105:17046-17049.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 17046-17049
-
-
Heijmans, B.T.1
-
28
-
-
47149100122
-
Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses
-
Oberlander TF, et al. (2008) Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics 3:97-106.
-
(2008)
Epigenetics
, vol.3
, pp. 97-106
-
-
Oberlander, T.F.1
-
29
-
-
84860545186
-
DNA methylation in neonates born to women receiving psychiatric care
-
Schroeder JW, et al. (2012) DNA methylation in neonates born to women receiving psychiatric care. Epigenetics 7:409-414.
-
(2012)
Epigenetics
, vol.7
, pp. 409-414
-
-
Schroeder, J.W.1
-
30
-
-
60749105468
-
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
-
McGowan PO, et al. (2009) Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci 12:342-348.
-
(2009)
Nat Neurosci
, vol.12
, pp. 342-348
-
-
McGowan, P.O.1
-
31
-
-
84872942417
-
Epigenetic vestiges of early developmental adversity: Childhood stress exposure and DNA methylation in adolescence
-
10.1111/j.1467-8624.2011.01641.x
-
Essex MJ, et al. (2011) Epigenetic vestiges of early developmental adversity: Childhood stress exposure and DNA methylation in adolescence. Child Dev, 10.1111/j.1467-8624.2011.01641.x.
-
(2011)
Child Dev
-
-
Essex, M.J.1
-
32
-
-
77249137168
-
Principles and challenges of genomewide DNA methylation analysis
-
Laird PW (2010) Principles and challenges of genomewide DNA methylation analysis. Nat Rev Genet 11:191-203.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 191-203
-
-
Laird, P.W.1
-
33
-
-
70149101327
-
Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinfl ammatory signaling
-
Miller GE, et al. (2009) Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinfl ammatory signaling. Proc Natl Acad Sci USA 106:14716-14721.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14716-14721
-
-
Miller, G.E.1
-
34
-
-
76549135113
-
Evolution in health and medicine Sackler colloquium: Stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease
-
Feinberg AP, Irizarry RA (2010) Evolution in health and medicine Sackler colloquium: Stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease. Proc Natl Acad Sci USA 107(Suppl 1):1757-1764.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.SUPPL. 1
, pp. 1757-1764
-
-
Feinberg, A.P.1
Irizarry, R.A.2
-
35
-
-
78649475003
-
Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
-
Du P, et al. (2010) Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis. BMC Bioinformatics 11:587.
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 587
-
-
Du, P.1
-
36
-
-
33846837386
-
Prevalence of Toll-like receptor signalling defects in apparently healthy children who developed invasive pneumococcal infection
-
DOI 10.1016/j.clim.2006.10.012, PII S1521661606009181
-
Hirschfeld AF, et al. (2007) Prevalence of Toll-like receptor signalling defects in apparently healthy children who developed invasive pneumococcal infection. Clin Immunol 122:271-278. (Pubitemid 46216916)
-
(2007)
Clinical Immunology
, vol.122
, Issue.3
, pp. 271-278
-
-
Hirschfeld, A.F.1
Bettinger, J.A.2
Victor, R.E.3
Davidson, D.J.4
Currie, A.J.5
Ansermino, J.M.6
Scheifele, D.W.7
Orange, J.S.8
Turvey, S.E.9
-
38
-
-
79959623531
-
Maternal warmth buffers the effects of low early-life socioeconomic status on pro-inflammatory signaling in adulthood
-
Chen E, Miller GE, Kobor MS, Cole SW (2011) Maternal warmth buffers the effects of low early-life socioeconomic status on pro-inflammatory signaling in adulthood. Mol Psychiatry 16:729-737.
-
(2011)
Mol Psychiatry
, vol.16
, pp. 729-737
-
-
Chen, E.1
Miller, G.E.2
Kobor, M.S.3
Cole, S.W.4
-
39
-
-
79960121131
-
The influence of aging, environmental exposures and local sequence features on the variation of DNA methylation in blood
-
Langevin SM, et al. (2011) The influence of aging, environmental exposures and local sequence features on the variation of DNA methylation in blood. Epigenetics 6:908-919.
-
(2011)
Epigenetics
, vol.6
, pp. 908-919
-
-
Langevin, S.M.1
-
40
-
-
79953706343
-
Tobacco-smoking-related differential DNA methylation: 27K discovery and replication
-
Breitling LP, Yang R, Korn B, Burwinkel B, Brenner H (2011) Tobacco-smoking-related differential DNA methylation: 27K discovery and replication. Am J Hum Genet 88:450-457.
-
(2011)
Am J Hum Genet
, vol.88
, pp. 450-457
-
-
Breitling, L.P.1
Yang, R.2
Korn, B.3
Burwinkel, B.4
Brenner, H.5
-
41
-
-
84863509978
-
Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome
-
Wan ES, et al. (2012) Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome. Hum Mol Genet 21:3073-3082.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 3073-3082
-
-
Wan, E.S.1
-
42
-
-
77953191946
-
Aging and chronic sun exposure cause distinct epigenetic changes in human skin
-
Grönniger E, et al. (2010) Aging and chronic sun exposure cause distinct epigenetic changes in human skin. PLoS Genet 6:e1000971.
-
(2010)
PLoS Genet
, vol.6
-
-
Grönniger, E.1
-
43
-
-
84858055958
-
Acute exercise remodels promoter methylation in human skeletal muscle
-
Barrès R, et al. (2012) Acute exercise remodels promoter methylation in human skeletal muscle. Cell Metab 15:405-411.
-
(2012)
Cell Metab
, vol.15
, pp. 405-411
-
-
Barrès, R.1
-
44
-
-
79952171975
-
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor
-
Ressler KJ, et al. (2011) Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor. Nature 470:492-497.
-
(2011)
Nature
, vol.470
, pp. 492-497
-
-
Ressler, K.J.1
-
45
-
-
84863057173
-
Differential patterns of whole-genome DNA methylation in institutionalized children and children raised by their biological parents
-
Naumova OY, et al. (2012) Differential patterns of whole-genome DNA methylation in institutionalized children and children raised by their biological parents. Dev Psychopathol 24:143-155.
-
(2012)
Dev Psychopathol
, vol.24
, pp. 143-155
-
-
Naumova, O.Y.1
-
46
-
-
84858800629
-
DNA methylation pro fi ling identi fies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients
-
Volkmar M, et al. (2012) DNA methylation pro fi ling identi fies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients. EMBO J 31:1405-1426.
-
(2012)
EMBO J
, vol.31
, pp. 1405-1426
-
-
Volkmar, M.1
-
47
-
-
80053457972
-
Identification of type 1 diabetes-associated DNA methylation variable positions that precede disease diagnosis
-
Rakyan VK, et al. (2011) Identification of type 1 diabetes-associated DNA methylation variable positions that precede disease diagnosis. PLoS Genet 7:e1002300.
-
(2011)
PLoS Genet
, vol.7
-
-
Rakyan, V.K.1
-
48
-
-
75649151209
-
Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
-
Javierre BM, et al. (2010) Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. Genome Res 20:170-179.
-
(2010)
Genome Res
, vol.20
, pp. 170-179
-
-
Javierre, B.M.1
-
49
-
-
38949212693
-
A novel CpG island set identifies tissue-specific methylation at developmental gene loci
-
Illingworth R, et al. (2008) A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol 6:e22.
-
(2008)
PLoS Biol
, vol.6
-
-
Illingworth, R.1
-
50
-
-
77649204292
-
Genetic control of individual differences in gene-specific methylation in human brain
-
Zhang D, et al. (2010) Genetic control of individual differences in gene-specific methylation in human brain. Am J Hum Genet 86:411-419.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 411-419
-
-
Zhang, D.1
-
51
-
-
77953223693
-
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain
-
Gibbs JR, et al. (2010) Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. PLoS Genet 6:e1000952.
-
(2010)
PLoS Genet
, vol.6
-
-
Gibbs, J.R.1
-
52
-
-
57749084635
-
A general framework for multiple testing dependence
-
Leek JT, Storey JD (2008) A general framework for multiple testing dependence. Proc Natl Acad Sci USA 105:18718-18723.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 18718-18723
-
-
Leek, J.T.1
Storey, J.D.2
|