Prenatal stress down-regulates Reelin expression by methylation of its promoter and induces adult behavioral impairments in rats

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Palacios García, Ismael ^a,d   Lara Vásquez, Ariel ^a   Montiel, Juan F ^b   Díaz Véliz, Gabriela F ^c   Sepúlveda, Hugo ^e   Utreras, Elías ^d   Montecino, Martín ^e   González Billault, Christian ^d   Aboitiz, Francisco ^a  

^a Centro de Neurociencias Integradas   (Chile)

^b UNIVERSIDAD DIEGO PORTALES   (Chile)

^c UNIVERSITY OF CHILE   (Chile)

^d UNIVERSITY OF CHILE   (Chile)

^e UNIVERSIDAD ANDRÉS BELLO   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

REELIN; CELL NUCLEUS ANTIGEN; CYCLIN DEPENDENT KINASE 5; NERVE CELL ADHESION MOLECULE; NERVE PROTEIN; NEUN PROTEIN, RAT; REELIN PROTEIN; SCLEROPROTEIN; SERINE PROTEINASE;

ADULT; ADULTHOOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR DISORDER; BIOCHEMISTRY; BRAIN CORTEX; BRAIN NERVE CELL; CAJAL RETZIUS NERVE CELL; CONTROLLED STUDY; CYTOLOGY; DEPTH PERCEPTION; DNA METHYLATION; DOWN REGULATION; FEMALE; IMMOBILIZATION STRESS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LEARNING DISORDER; LOCOMOTION; MALE; MEMORY CONSOLIDATION; MEMORY DISORDER; MOLECULAR BIOLOGY; MORRIS WATER MAZE TEST; NONHUMAN; PRENATAL STRESS; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; ANIMAL; ANIMAL BEHAVIOR; DISEASE MODEL; GENETICS; MATERNAL EXPOSURE; MENTAL DISORDERS; MENTAL STRESS; METABOLISM; NERVE CELL; NEWBORN; PHYSIOLOGICAL STRESS; PREGNANCY; PRENATAL EXPOSURE;

ANIMALIA; RATTUS;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, NUCLEAR; BEHAVIOR, ANIMAL; CELL ADHESION MOLECULES, NEURONAL; CEREBRAL CORTEX; CYCLIN-DEPENDENT KINASE 5; DISEASE MODELS, ANIMAL; DNA METHYLATION; EXTRACELLULAR MATRIX PROTEINS; FEMALE; MATERNAL EXPOSURE; MENTAL DISORDERS; NERVE TISSUE PROTEINS; NEURONS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROMOTER REGIONS, GENETIC; RATS; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; STRESS, PSYCHOLOGICAL;

EID: 84923052480     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0117680     Document Type: Article

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