Prenatal stress induces spatial memory deficits and epigenetic changes in the hippocampus indicative of heterochromatin formation and reduced gene expression

Behavioural Brain Research

Volumn 281, Issue , 2015, Pages 1-8

  Benoit, Jamie D ^a   Rakic, Pasko ^b   Frick, Karyn M ^c  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

Author keywords

Chronic unpredictable stress; DNA methyltransferase; Histone acetylation; Morris water maze; Mouse; Sex differences

Indexed keywords

CORTICOSTERONE; DNA METHYLTRANSFERASE 1; HISTONE H3; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; HETEROCHROMATIN; HISTONE;

ADULT; AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CORTICOSTERONE BLOOD LEVEL; DISEASE PREDISPOSITION; DNA METHYLATION; ENZYME BLOOD LEVEL; EPIGENETICS; FEMALE; GENE EXPRESSION; HETEROCHROMATIN; HIPPOCAMPUS; HISTONE ACETYLATION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; MORRIS WATER MAZE TEST; MOUSE; NONHUMAN; PRENATAL STRESS; PROGENY; SPATIAL MEMORY; ACETYLATION; ANIMAL; BLOOD; C57BL MOUSE; COMPLICATION; GENETIC EPIGENESIS; GENETICS; MAZE TEST; MEMORY DISORDER; MENTAL STRESS; METABOLISM; PREGNANCY; PRENATAL EXPOSURE; PSYCHOLOGY; RISK FACTOR; SEX DIFFERENCE;

ACETYLATION; ANIMALS; CORTICOSTERONE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION; HETEROCHROMATIN; HIPPOCAMPUS; HISTONES; MALE; MAZE LEARNING; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RISK FACTORS; SEX FACTORS; SPATIAL MEMORY; STRESS, PSYCHOLOGICAL;

EID: 84920896517     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2014.12.001     Document Type: Article

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