Programming placental nutrient transport capacity

Journal of Physiology

Volumn 572, Issue 1, 2006, Pages 5-15

  Fowden, A L ^a   Ward, J W ^a   Wooding, F P B ^a   Forhead, A J ^a   Constancia, M ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; GLUCOCORTICOID; GROWTH FACTOR; PLACENTA ENZYME; PLACENTA LACTOGEN; PROGESTERONE; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; 15 HYDROXYPROSTAGLANDIN DEHYDROGENASE; CARRIER PROTEIN; HYDROCORTISONE; PROSTAGLANDIN H;

CONFERENCE PAPER; ENVIRONMENTAL EXPOSURE; FEMALE; FETAL MALNUTRITION; FETUS; FETUS GROWTH; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION REGULATION; GENE FUNCTION; HORMONE METABOLISM; HORMONE SYNTHESIS; HUMAN; INTRAUTERINE GROWTH RETARDATION; MOLECULAR MECHANICS; MOTHER FETUS RELATIONSHIP; NONHUMAN; NUTRIENT SUPPLY; PHENOTYPE; PLACENTA CIRCULATION; PLACENTA DEVELOPMENT; PLACENTA DISORDER; PLACENTAL TRANSFER; PREGNANCY DISORDER; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ARTICLE; GENE; IGF2 GENE; MORPHOLOGY; NUTRIENT UPTAKE; PLACENTA WEIGHT; PRENATAL DEVELOPMENT;

AGING; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; FEMALE; FETAL DEVELOPMENT; HUMANS; MATERNAL-FETAL EXCHANGE; PLACENTA; PLACENTAL CIRCULATION; PREGNANCY; PRENATAL NUTRITION PHYSIOLOGY; PROTEINS;

EID: 33645308782     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2005.104141     Document Type: Conference Paper

References (100)

1. Ain R, Canhan LN & Soares MJ (2005). Dexamethasane-induced intrauterine growth retardation impacts the placental prolactin family, insulin-like growth factor-II and Akt signaling pathway. J Endo 185, 253-263.
2. Alexander G (1964). Studies on the placenta of the sheep (Ovis avis L.): placental size. J Reprod Fert 7, 289-305.
3. Allen WR, Wilsher S, Turnbull C, Stewart F, Ousey J, Rossdale PD & Fowden AL (2002). Influence of maternal size on placental, fetal and postnatal growth in the horse. I. Development in utero. Reproduction 123, 454-465.
4. Barbera A, Wilkening RB, Teng C, Battaglia FC & Meschia G (1997). Metabolic alterations in the fetal hepatic and umbilical circulations during glucocorticoid-induced parturition in sheep. Ped Res 41, 242-248.
5. Barker DJP (1994). Mothers, Babies and Disease. BMJ Publishing Group, London.
6. Baur R (1977). Morphometry of the placental exchange area. Adv Anat Emb Cell Bio 53, 1-63.
7. Bell AW, Hay WW & Ehrhardt RA (1999). Placental transport of nutrients and its implications for fetal growth. J Reprod Fert Suppl 54, 401-410.
8. Biensen NJ, Wilson ME & Ford SP (1999). The impacts of uterine environment and fetal genotype on conceptus size and placental vascularity during late gestation in pigs. J Anim Sci 77, 954-959.
9. 2α concentrations and nocturnal myometrial electromyographic activity in the pregnant rhesus monkey in the last third of gestation: A mode of preterm labor? Am J Obstet Gynecol 160, 746-750.
10. 2 consumption after long term hypoglycaemia in pregnant sheep. Am J Physiol 269, E299-E308.
11. Chiao E, Fisher P, Crisponi L, Deiana M, Dragatsis I, Schlersinger D, Pilia G & Efstratiadis A (2002). Overgrowth of a mouse model of the Simpson-Golabi-Behmel syndrome is independent of IGF signalling. Devel Biol 243, 185-206.
12. Clarke K, Ward JW, Forhead AJ, Giussani DA & Fowden AL (2002). Regulation of 11β-hydroxysteroid dehydrogenase type 2 activity in ovine placenta by fetal cortisol. J Endo 172, 527-534.
13. Coan PM, Ferguson-Smith AC & Burton GJ (2004). Developmental dynamics of the definitive mouse placenta assessed by stereology. Biol Reprod 70, 1806-1813.
14. Coan P, Ferguson-Smith AC & Burton GJ (2005). Imprinted genes in the placenta - a review. Placenta 26 (Suppl. A), S10-S20.
15. Constancia M, Angiolini E, Sandovic I, Smith P, Smith R, Kelsey G, Dean W, Ferguson-Smith A, Sibley C, Reik W & Fowden AL (2005). Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems. Proc Natl Acad Sci U S A 102, 19219-19224.
16. Constancia M, Hemburger M, Hughes J, Dean W, Ferguson-Smith A, Fundele R, Stewart F, Kelsey G, Fowden A, Sibley C & Reik W (2002). Placental-specific IGF2 is a major modulator of placental and fetal growth. Nature 417, 945-948.
17. Currie MJ, Bassett NS & Gluckman PD (1997). Ovine glucose transporter-1 and -3: Partial sequence and development expression in the placenta. Placenta 18, 393-401.
18. Dandrea J, Wilson ME, Gopalakrishna G, Heasman L, Budpa H, Stephenson T & Symonds ME (2001). Maternal nutritional manipulation of placental growth and glucose transporter 1 (GLUT1) abundance in sheep. Reproduction 122, 793-800.
19. Das UG, Farouk Sadiq H, Soares MJ, Hay WW & Devaskar SU (1998). Time dependent physiological regulation of rodent and ovine glucose transporter (GLUT-1) protein. Am J Physiol 274, R339-R347.
20. Das UG, He J, Ehrhardt RA, Hay WW & Devaskar SW (2000). Time dependent physiological regulation of ovine placental Glut-3 transporter protein. Am J Physiol 279, R2252-R2261.
21. Davis SR, Rattray RV, Petch ME & Duganzich DM (1981). Interrelationships of placental development with nutrition in pregnancy and lamb birth weight. Proc NZ Soc Prod 41, 218-223.
22. Edwards LJ & McMillen IC (2001). Maternal undernutrition increases arterial blood pressure in the sheep fetus during late gestation. J Physiol 533, 561-570.
23. Efstratiadis A (1998). Genetics of mouse growth. Int J Dev Biol 42, 955-976.
24. Faichney GJ & White GA (1987). Effects of maternal nutritional status on fetal and placental growth and on fetal urea synthesis in sheep. Aust J Biol Sci 40, 365-377.
25. Ferrell CL (1991). Maternal and fetal influences on uterine and conceptus in the cow. I. Growth of tissues of the gravid uterus. J Anim Sci 69, 1945-1953.
26. Fowden AL (1997). Comparative aspects of fetal carbohydrate metabolism. Equin Vet J 24 (Suppl.), 19-25.
27. Fowden AL (2003). The insulin-like growth factors and feto-placental growth. Placenta 24, 803-812.
28. Fowden AL & Forhead AJ (2004). Endocrine mechanisms of intrauterine programming. Reproduction 127, 515-526.
29. Fowden AL, Giussanni DA & Forhead AJ (2005). Endocrine and metabolic programming during intrauterine development. Early Hum Dev 81, 723-734.
30. Fowden AL, Li J & Forhead AJ (1998a). Glucocorticoids and the preparation for life after birth: Are there long term consequences of the life insurance? Proc Nutr Soc 57, 113-122.
31. Fowden AL, Mundy L & Silver M (1998b). Developmental regulation of glucogenesis in the sheep fetus during late gestation. J Physiol 508, 937-947.
32. Fowden AL, Ouey JC & Forhead AJ (2001). Comparative aspects of prepartum maturation; provision of nutrients. Pferdeheilkunde 17, 653-658.
33. Fowden AL, Ralph M & Silver M (1994). Nutritional regulation of uteroplacental prostraglandin production and metabolism in pregnant ewes and mares during late gestation. Exp Clin Endo 102, 212-221.
34. Fowden AL, Sibley C, Reik W & Constancia M (2006). Imprinted genes, placental development and fetal growth. Hormone Res (in press).
35. Gardner DS, Ward JW, Giussani DA & Fowden AL (2002). The effects of a reversible period of adverse intrauterine conditions during late gestation on fetal and placental weight and placetome distribution in sheep. Placenta 23, 459-466.
36. Hahn T, Barth S, Graf R, Engleman M, Beslapic D, Reul JM, Holsboer F, Dohr G & Desoye G (1999). Placental glucose transporter expression is regulated by glucocorticoids. J Clin Endo Metab 84, 1445-1452.
37. Hanguel-de Mouzon S & Shafrir E (2001). Carbohydrate and fat metabolism and related hormonal regulation in normal and diabetic placenta. Placenta 22, 619-627.
38. Harding JE, Evans PC & Gluckman PD (1997). Maternal growth hormone treatment increases placental diffusion capacity but not fetal or placental growth in sheep. Endo 138, 5352-5358.
39. Harding JE & Johnston BM (1995). Nutrition and fetal growth. Reprod Fert Dev 7, 539-547.
40. Hay WW (1995). Regulation of placental metabolism by glucose supply. Reprod Fert Dev 7, 365-375.
41. Hay WW, Sparks JW, Wilkening RB, Battaglia FC & Meschia G (1983). Partition of maternal glucose production between conceptis and maternal tissues in sheep. Am J Physiol 245, E347-E350.
42. Heasman L, Clarke L, Firth K, Stephenson T & Symonds ME (1998). Influence of restricted maternal nutrition in early to mid gestation on placental and fetal development at term in sheep. Ped Res 44, 546-551.
43. Heasman L, Clarke L, Stephenson TJ & Symonds ME (1999). The influence of maternal nutrient restriction in early to mid-gestation on placental and fetal development in sheep. Proc Nutr Soc 58, 283-288.
44. Holst PJ, Allan CJ & Gilmour AR (1992). Effects of restricted diet during mid pregnancy of ewes on uterine and fetal growth and lamb birth weight. Aust J Agric Res 43, 315-324.
45. Jansson T, Yives K, Wengren M & Powell TL (2003). Glucose transport and system A activity in the syncytiotrophoblast microvillous and basal membranes in intrauterine growth retardation. Placenta 23, 386-391.
46. Jellyman JK, Gardner DS, Fowden AL & Guissani DA (2004). Effects of dexamethasone on the uterine and umbilical vascular beds during basal and hypoxemic conditions in sheep. Am J Obstet Gynec 190, 825-835.
47. Jensen EG, Gallaher BW, Breier BH & Harding JE (2002). The effect of chronic maternal cortisol infusion on the late-gestation fetal sheep. J Endo 174, 27-36.
48. Johnson JWC, Mitzner W, London WT, Palmer AE & Scott R (1979). Betamethasone and the rhesus fetus: Multisystemic effects. Am J Obstet Gynec 133, 677-684.
49. Kelly RW (1992). Nutrition and placental development. Proc Nutr Soc Aust 17, 203-211.
50. Langdown ML & Sugden MC (2001). Enhanced placental GLUT1 and GLUT3 expression in dexamethasone-induced fetal growth retardation. Mol Cell Endo 185, 109-117.
51. Lesage J, Hahn D, Leonhardt M, Bondeau B, Breant B & Duprey JP (2002). Maternal undernutrition during late gestation-induced intrauterine growth restriction in the rat is associated with impaired placental GLUT3 expression but does not correlate with endogenous corticosterone levels. J Endo 174, 37-43.
52. Liechty EA, Barone S & Nutt M (1987). Effect of maternal fasting on ovine fetal and maternal branched-chain amino acid transamitrase activities. Biol Neonate 52, 166-173.
53. Liu L, Harding JE, Evans PC & Gluckman PD (1994). Maternal insulin-like growth factor-I infusion alters feto-placental carbohydrate and protein metabolism in pregnant sheep. Endo 135, 895-900.
54. Lopez MF, Dikkes P, Zurakkowski D & Villa-Komarott L (1996). Insulin-like growth factor II affects the appearance and glycogen content of glycogen cells in the murine placenta. Endo 137, 2100-2108.
55. Lumey LH (1998). Compensatory placental growth after restriction of maternal nutrition in early pregnancy. Placenta 19, 105-111.
56. Macdonald AA & Fowden AL (1997). Microscopic anatomy of the ungulate placenta. Equine Vet J 24 (Suppl.), 7-13.
57. McGrabb GH, Hosking BJ & Egan AR (1992). Changes in the maternal body and feto-placental growth following various lengths of feed restriction during mid-pregnancy in sheep. Aust J Agri Res 43, 1429-1440.
58. McMillen IC & Robinson JS (2005). Developmental origins of metabolic syndrome: Prediction, plasticity and programming. Physiol Rev 85, 571-633.
59. Matthews JC, Beveridge MJ, Dialynas E, Bartke A, Kilberg MS & Novak DA (1999). Placental anionic and cationic amino acid transporter expression in growth hormone over expressing and null IGF-II or null IGF-I receptor mice. Placenta 20, 639-650.
60. Mellor DJ (1983). Nutritional and placental determinants of foetal growth rate in sheep and consequences for the newborn lamb. Br Vet J 139, 307-324.
61. Molina RD, Meschia G, Battaglia FC & Hay WW (1991). Gestational maturation of placental glucose transfer capacity in sheep. Am J Physiol 261, R697-R704.
62. Moritz KM, Boon WM & Wintour EM (2005). Glucocortioid programming and adult disease. Cell Tissue Res 322, 81-88.
63. Oliver MH, Hawkins P & Harding JE (2005). Periconceptual undernutrition alters growth trajectory and metabolic and endocrine response to fasting in late gestation fetal sheep. Ped Res 57, 591-598.
64. Osgerby JC, Wathes DC, Howard D & Gadd TS (2002). The effect of maternal undernutrition on ovine fetal growth. J Endo 173, 131-141.
65. Osgerby JC, Wathes DC, Howard D & Gadd TS (2004). The effect of maternal undernutrition on the placental growth trajectory and the uterine insulin-like growth factor axis in the pregnant ewe. J Endo 182, 89-103.
66. Owens JA, Falconer J & Robinson JS (1987). Restriction of placental size in the sheep enhances the efficiency of placental transfer of antipyrine, 3-O-methy-D-glucose but not of urea. J Dev Physiol 9, 457-464.
67. Owens JA, Falconer J & Robinson JS (1989). Glucose metabolism in pregnant sheep when placental growth is restricted. Am J Physiol 257, R350-R357.
68. Penninga L & Longo LD (1998). Ovine placentome morphology: Effect of high altitude, long-term hypoxia. Placenta 19, 187-193.
69. Pond WG, Maurer RR & Klindt J (1991). Fetal organ response to maternal protein deprivation during pregnancy in swine. J Nutr 121, 504-509.
70. Redmer DA, Wallace JM & Reynolds LP (2004). Effect of nutrient intake during pregnancy on fetal and placental growth and vascular development. Dom Anim Endo 27, 199-217.
71. Regnault TRH, Friedman JE, Wilkening RB, Anthony RV & Hay WW (2005). Fetoplacental transport and utilization of amino acids in IUGR. A review. Placenta 26 (Suppl. 1), S52-S62.
72. Reynolds LP, Borawicz PP, Vonnahme KA, Johnson ML, Grazul-Bilska AT, Wallace JM, Caton JS & Redmer DA (2005). Animal models of placental angiogenesis. Placenta 26, 689-708.
73. Roberts CT, Sohlstrom A, Kind KL, Karl RA, Khong TY, Robinson JS, Owens PC & Owens JA (2001). Maternal food restriction reduces the exchange surface area and increases the barrier thickness of the placenta in the guinea-pig. Placenta 22, 177-185.
74. Ross JC, Fennessey PV, Wilkening RP, Battaglia FC & Meschia G (1996). Placental transport and fetal utilization of leucine in a model of fetal growth retardation. Am J Physiol 270, E491-E503.
75. Seckl JR & Meaney MJ (2004). Glucocorticoid programming. Ann NY Acad Sci 1032, 63-84.
76. Sibley CP, Coan PM, Ferguson-Smith AC, Dean W, Hughes J, Smith P, Reik W, Burton GB, Fowden AL & Constancia M (2004). Placenta-specific Igf2 regulates the diffusional exchange characteristics of the mouse placenta. Pro Natl Acad Sci U S A 101, 8204-8208.
77. Sibley C, Glazier J & D'Souza A (1997). Placental transporter activity and expression in relation to fetal growth. Exp Physiol 82, 389-402.
78. Sibley C, Turner MA, Cetin I, Ayuk P, Boyd R, D'Souza SW, Glazier JD, Greenwood SL, Jansson T & Powell T (2005). Placental phenotypes of intrauterine growth. Ped Res 58, 827-832.
79. Silver M, Barnes RJ, Comline RS & Burton GJ (1982). Placental blood flow: Some fetal and maternal cardiovascular adjustments during gestation. J Reprod Fert Suppl 31, 139-160.
80. Stegeman HJ (1975). Placental development in the sheep and its relation to fetal development. BiJdragen V Dierkunde 44, 3-73.
81. Steven DH (1975). Comparative Placentation. Academic Press, London.
82. Steven DH (1982). Placentation in the mare. J Reprod Fert 31, 41-55.
83. Steyn C, Hawkins P, Saito T, Noakes DE, Kingdon JCP & Hanson MA (2001). Undernutrition during the first half of gestation increases the predominance of fetal tissue in late gestation ovine placentomes. Eur J Obstet Gynec Reprod Biol 98, 165-170.
84. Tangalakis K, Moritz KM, Shandley Y & Wintour EM (1995). Effect of maternal glucocorticoid treatment on ovine fetal fluids at 0.6 gestation. Reprod Fert Dev 7, 1595-1598.
85. Thureen PJ, Anderson SM & Hay WW (2000). Regulation of uterine and amino acid uptakes by maternal amino acid concentrations. Am J Physiol 279, R849-R859.
86. Thureen PJ, Trembler KA, Meschia G, Makowski EL & Wilkening RB (1992). Placental glucose transport in heat-induced fetal growth retardation. Am J Physiol 263, R578-R585.
87. Timmerman M, Teng C, Wilkening RP, Fennessey P, Battaglia FC & Meschia G (2000). Effect of dexamethasone on fetal hepatic glutamine-glutanate exchange. Am J Physiol 278, E839-E845.
88. Vatnick I, Schoknect IPA, Danigrad R & Bell AW (1991). Growth and metabolism of the placenta after unilateral fetectomy in twin pregnant ewes. J Dev Physiol 15, 351-356.
89. Wallace JM, Bourke DA, Aitken RP, Milne S & Hay WW (2002). Placental glucose transport in growth restricted pregnancies induced by overnourishing adolescent sheep. J Physiol 547, 85-94.
90. Ward JW, Forhead AJ, Wooding FBP & Fowden AL (2006). Functional significance and cortisol dependence of the gross morphology of ovine placetome during late gestation. Biol Reprod (in press).
91. Ward JW, Wooding FBP & Fowden AL (2002). The effect of cortisol on the binucleate cell population in the ovine placenta during late gestation. Placenta 23, 451-458.
92. Ward JW, Wooding FPB & Fowden AL (2004). Ovine feto-placental metabolism. J Physiol 554, 529-541.
93. Whittle WL, Patel FA, Alfaidy N, Holloway AC, Fraser M, Gyomovey S, Lye SJ, Gibb W & Challis JRG (2001). Glucocorticoid regulation of human and ovine parturition: The relationship between fetal hypothalamic-pituitary-adrenal axis activation and intrauterine prostaglad production. Biol Reprod 64, 1019-1032.
94. Whorwood CB, Firth KM, Budge H & Symonds ME (2001). Maternal undernutrition during early to mid gestatic programs tissue-specific alterations in the expression of the glucocorticoid receptor, 11β hydroxsterond dehydrogenase isoforms, and type I angiotensin II receptor in neonatal sheep. Endocrinology 142, 2854-2864.
95. Wilson ME, Biensen NJ, Young CR & Ford SP (1998). Development of Meishan and Yorkshire litter mate conceptures in either a Meishan or Yorkshire uterine environment to Day 90 of gestation or to term. Biol Reprod 58, 905-910.
96. Woodall SM, Breier BH, Johnston BM & Gluckman PD (1996). A model of intrauterine growth retardation caused by chronic maternal undernutrition in the rat: Effects on the sonatrotrophic axis and postnatal growth. J Endocrinol 150, 231-242.
97. Wooding FBP & Flint APF (1994). Placentation. In Marshall's Physiology of Reproduction, 4th edn, ed. Lamming GE, pp. 233-460. Chapman & Hall, London.
98. Wooding FBP & Fowden AL (2006). Nutrient transfer in the equine placenta: Correlation of structure and function. Equine Vet J (in press).
99. Wooding FBP, Fowden AL, Bell AW, Ehrhardt RA, Limesand SW & Hay WW (2005). Localisation of glucose transport in the ruminant placenta: implications for sequential use of transporter isoforms. Placenta 26, 626-640.
100. Zhou A & Bondy CA (1993). Placental transporter gene expression and metabolism in the rat. J Clin Invest 91, 845-852.