-
1
-
-
5344234787
-
The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs
-
Kipp, J.E., The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs. Int. J. Pharm. 284 (2004), 109–122.
-
(2004)
Int. J. Pharm.
, vol.284
, pp. 109-122
-
-
Kipp, J.E.1
-
2
-
-
0036742053
-
Poor aqueous solubility: an industry wide problem in drug discovery
-
Lipinski, C.A., Poor aqueous solubility: an industry wide problem in drug discovery. Am. Pharm. Rev. 5 (2002), 82–85.
-
(2002)
Am. Pharm. Rev.
, vol.5
, pp. 82-85
-
-
Lipinski, C.A.1
-
3
-
-
0032054501
-
Innovative strategies for the oral delivery of drugs and peptides
-
Fasano, A., Innovative strategies for the oral delivery of drugs and peptides. Trends Biotechnol. 16 (1998), 152–157.
-
(1998)
Trends Biotechnol.
, vol.16
, pp. 152-157
-
-
Fasano, A.1
-
4
-
-
78049499869
-
New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs
-
Müllertz, A., Ogbonna, A., Ren, S., Rades, T., New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs. J. Pharm. Pharmacol. 62 (2010), 1622–1636.
-
(2010)
J. Pharm. Pharmacol.
, vol.62
, pp. 1622-1636
-
-
Müllertz, A.1
Ogbonna, A.2
Ren, S.3
Rades, T.4
-
5
-
-
84866099781
-
Improvement of physicochemical properties of an antiepileptic drug by salt engineering
-
Rahman, Z., Zidan, A.S., Samy, R., Sayeed, V.A., Khan, M.A., Improvement of physicochemical properties of an antiepileptic drug by salt engineering. AAPS PharmSciTech 13 (2012), 793–801.
-
(2012)
AAPS PharmSciTech
, vol.13
, pp. 793-801
-
-
Rahman, Z.1
Zidan, A.S.2
Samy, R.3
Sayeed, V.A.4
Khan, M.A.5
-
6
-
-
84879714763
-
Use of pharmaceutical salts and cocrystals to address the issue of poor solubility
-
Elder, D.P., Holm, R., de Diego, H.L., Use of pharmaceutical salts and cocrystals to address the issue of poor solubility. Int. J. Pharm. 453 (2013), 88–100.
-
(2013)
Int. J. Pharm.
, vol.453
, pp. 88-100
-
-
Elder, D.P.1
Holm, R.2
de Diego, H.L.3
-
7
-
-
0031125683
-
Lipid-based vehicles for the oral delivery of poorly water soluble drugs
-
Humberstone, A.J., Charman, W.N., Lipid-based vehicles for the oral delivery of poorly water soluble drugs. Adv. Drug Deliver. Rev. 25 (1997), 103–128.
-
(1997)
Adv. Drug Deliver. Rev.
, vol.25
, pp. 103-128
-
-
Humberstone, A.J.1
Charman, W.N.2
-
8
-
-
0031914282
-
Lipid-based delivery systems for improving the bioavailability and lymphatic transport of a poorly water-soluble LTB4 inhibitor
-
Hauss, D.J., Fogal, S.E., Ficorilli, J.V., Price, C.A., Roy, T., Jayaraj, A.A., Keirns, J.J., Lipid-based delivery systems for improving the bioavailability and lymphatic transport of a poorly water-soluble LTB4 inhibitor. J. Pharm. Sci. 87 (1998), 164–169.
-
(1998)
J. Pharm. Sci.
, vol.87
, pp. 164-169
-
-
Hauss, D.J.1
Fogal, S.E.2
Ficorilli, J.V.3
Price, C.A.4
Roy, T.5
Jayaraj, A.A.6
Keirns, J.J.7
-
9
-
-
84982845000
-
Amorphous solid dispersions or prodrugs: complementary strategies to increase drug absorption
-
Rumondor, A.C., Dhareshwar, S.S., Kesisoglou, F., Amorphous solid dispersions or prodrugs: complementary strategies to increase drug absorption. J. Pharm. Sci. 105 (2016), 2498–2508.
-
(2016)
J. Pharm. Sci.
, vol.105
, pp. 2498-2508
-
-
Rumondor, A.C.1
Dhareshwar, S.S.2
Kesisoglou, F.3
-
10
-
-
84973295204
-
Nanomilling of drugs for bioavailability enhancement: a holistic formulation-process perspective
-
Li, M., Azad, M., Davé, R., Bilgili, E., Nanomilling of drugs for bioavailability enhancement: a holistic formulation-process perspective. Pharmaceutics, 8, 2016, 17.
-
(2016)
Pharmaceutics
, vol.8
, pp. 17
-
-
Li, M.1
Azad, M.2
Davé, R.3
Bilgili, E.4
-
11
-
-
0037312695
-
Nanosizing: a formulation approach for poorly-water-soluble compounds
-
Merisko-Liversidge, E., Liversidge, G.G., Cooper, E.R., Nanosizing: a formulation approach for poorly-water-soluble compounds. Eur. J. Pharm. Sci. 18 (2003), 113–120.
-
(2003)
Eur. J. Pharm. Sci.
, vol.18
, pp. 113-120
-
-
Merisko-Liversidge, E.1
Liversidge, G.G.2
Cooper, E.R.3
-
12
-
-
0032885450
-
Solid dispersion of poorly water-soluble drugs: early promises, subsequent problems, and recent breakthroughs
-
Serajuddin, A., Solid dispersion of poorly water-soluble drugs: early promises, subsequent problems, and recent breakthroughs. J. Pharm. Sci. 88 (1999), 1058–1066.
-
(1999)
J. Pharm. Sci.
, vol.88
, pp. 1058-1066
-
-
Serajuddin, A.1
-
13
-
-
0026072621
-
Solid dispersions of indomethacin and griseofulvin in non-porous fumed silicon dioxide, prepared by melting
-
Nakagami, H., Solid dispersions of indomethacin and griseofulvin in non-porous fumed silicon dioxide, prepared by melting. Chem. Pharm. Bull. 39 (1991), 2417–2421.
-
(1991)
Chem. Pharm. Bull.
, vol.39
, pp. 2417-2421
-
-
Nakagami, H.1
-
14
-
-
84931041404
-
Improved aqueous solubility and antihypercholesterolemic activity of ezetimibe on formulating with hydroxypropyl-β-cyclodextrin and hydrophilic auxiliary substances
-
Srivalli, K.M.R., Mishra, B., Improved aqueous solubility and antihypercholesterolemic activity of ezetimibe on formulating with hydroxypropyl-β-cyclodextrin and hydrophilic auxiliary substances. AAPS PharmSciTech 17 (2016), 272–283.
-
(2016)
AAPS PharmSciTech
, vol.17
, pp. 272-283
-
-
Srivalli, K.M.R.1
Mishra, B.2
-
15
-
-
43949103740
-
Effect of β-cyclodextrin and hydroxypropyl β-cyclodextrin complexation on physicochemical properties and antimicrobial activity of cefdinir
-
Aleem, O., Kuchekar, B., Pore, Y., Late, S., Effect of β-cyclodextrin and hydroxypropyl β-cyclodextrin complexation on physicochemical properties and antimicrobial activity of cefdinir. J. Pharm. Biomed. Anal. 47 (2008), 535–540.
-
(2008)
J. Pharm. Biomed. Anal.
, vol.47
, pp. 535-540
-
-
Aleem, O.1
Kuchekar, B.2
Pore, Y.3
Late, S.4
-
16
-
-
79960616705
-
Investigation of preparation parameters of nanosuspension by top-down media milling to improve the dissolution of poorly water-soluble glyburide
-
Singh, S.K., Srinivasan, K., Gowthamarajan, K., Singare, D.S., Prakash, D., Gaikwad, N.B., Investigation of preparation parameters of nanosuspension by top-down media milling to improve the dissolution of poorly water-soluble glyburide. Eur. J. Pharm. Biopharm. 78 (2011), 441–446.
-
(2011)
Eur. J. Pharm. Biopharm.
, vol.78
, pp. 441-446
-
-
Singh, S.K.1
Srinivasan, K.2
Gowthamarajan, K.3
Singare, D.S.4
Prakash, D.5
Gaikwad, N.B.6
-
17
-
-
84863450309
-
Nanoparticulation of probucol, a poorly water-soluble drug, using a novel wet-milling process to improve in vitro dissolution and in vivo oral absorption
-
Tanaka, Y., Inkyo, M., Yumoto, R., Nagai, J., Takano, M., Nagata, S., Nanoparticulation of probucol, a poorly water-soluble drug, using a novel wet-milling process to improve in vitro dissolution and in vivo oral absorption. Drug Dev. Ind. Pharm. 38 (2012), 1015–1023.
-
(2012)
Drug Dev. Ind. Pharm.
, vol.38
, pp. 1015-1023
-
-
Tanaka, Y.1
Inkyo, M.2
Yumoto, R.3
Nagai, J.4
Takano, M.5
Nagata, S.6
-
18
-
-
33947487639
-
The rate of solution of solid substances in their own solutions
-
Noyes, A.A., Whitney, W.R., The rate of solution of solid substances in their own solutions. J. Am. Chem. Soc. 19 (1897), 930–934.
-
(1897)
J. Am. Chem. Soc.
, vol.19
, pp. 930-934
-
-
Noyes, A.A.1
Whitney, W.R.2
-
19
-
-
79953162538
-
State of the art of nanocrystals – special features, production, nanotoxicology aspects and intracellular delivery
-
Müller, R.H., Gohla, S., Keck, C.M., State of the art of nanocrystals – special features, production, nanotoxicology aspects and intracellular delivery. Eur. J. Pharm. Biopharm. 78 (2011), 1–9.
-
(2011)
Eur. J. Pharm. Biopharm.
, vol.78
, pp. 1-9
-
-
Müller, R.H.1
Gohla, S.2
Keck, C.M.3
-
20
-
-
84893902626
-
Recent advancements in mechanical reduction methods: particulate systems
-
Leleux, J., Williams, R.O., Recent advancements in mechanical reduction methods: particulate systems. Drug Dev. Ind. Pharm. 40 (2014), 289–300.
-
(2014)
Drug Dev. Ind. Pharm.
, vol.40
, pp. 289-300
-
-
Leleux, J.1
Williams, R.O.2
-
21
-
-
34548049483
-
Nanosizing—oral formulation development and biopharmaceutical evaluation
-
Kesisoglou, F., Panmai, S., Wu, Y., Nanosizing—oral formulation development and biopharmaceutical evaluation. Adv. Drug Deliver. Rev. 59 (2007), 631–644.
-
(2007)
Adv. Drug Deliver. Rev.
, vol.59
, pp. 631-644
-
-
Kesisoglou, F.1
Panmai, S.2
Wu, Y.3
-
22
-
-
41949100244
-
Drug nanoparticles: formulating poorly water-soluble compounds
-
Merisko-Liversidge, E.M., Liversidge, G.G., Drug nanoparticles: formulating poorly water-soluble compounds. Toxicol. Pathol. 36 (2008), 43–48.
-
(2008)
Toxicol. Pathol.
, vol.36
, pp. 43-48
-
-
Merisko-Liversidge, E.M.1
Liversidge, G.G.2
-
23
-
-
54349125120
-
Production and in vitro characterization of solid dosage form incorporating drug nanoparticles
-
Basa, S., Muniyappan, T., Karatgi, P., Prabhu, R., Pillai, R., Production and in vitro characterization of solid dosage form incorporating drug nanoparticles. Drug Dev. Ind. Pharm. 34 (2008), 1209–1218.
-
(2008)
Drug Dev. Ind. Pharm.
, vol.34
, pp. 1209-1218
-
-
Basa, S.1
Muniyappan, T.2
Karatgi, P.3
Prabhu, R.4
Pillai, R.5
-
24
-
-
48849111481
-
Drying of crystalline drug nanosuspensions—the importance of surface hydrophobicity on dissolution behavior upon redispersion
-
Van Eerdenbrugh, B., Froyen, L., Van Humbeeck, J., Martens, J.A., Augustijns, P., Van den Mooter, G., Drying of crystalline drug nanosuspensions—the importance of surface hydrophobicity on dissolution behavior upon redispersion. Eur. J. Pharm. Sci. 35 (2008), 127–135.
-
(2008)
Eur. J. Pharm. Sci.
, vol.35
, pp. 127-135
-
-
Van Eerdenbrugh, B.1
Froyen, L.2
Van Humbeeck, J.3
Martens, J.A.4
Augustijns, P.5
Van den Mooter, G.6
-
25
-
-
84891597533
-
Redispersible fast dissolving nanocomposite microparticles of poorly water-soluble drugs
-
Bhakay, A., Azad, M., Bilgili, E., Dave, R., Redispersible fast dissolving nanocomposite microparticles of poorly water-soluble drugs. Int. J. Pharm. 461 (2014), 367–379.
-
(2014)
Int. J. Pharm.
, vol.461
, pp. 367-379
-
-
Bhakay, A.1
Azad, M.2
Bilgili, E.3
Dave, R.4
-
26
-
-
0141507950
-
Drug nano- and microparticles processed into solid dosage forms: Physical properties
-
Lee, J., Drug nano- and microparticles processed into solid dosage forms: Physical properties. J. Pharm. Sci. 92 (2003), 2057–2068.
-
(2003)
J. Pharm. Sci.
, vol.92
, pp. 2057-2068
-
-
Lee, J.1
-
27
-
-
84928575619
-
Spray drying of drug-swellable dispersant suspensions for preparation of fast-dissolving, high drug-loaded, surfactant-free nanocomposites
-
Azad, M., Arteaga, C., Abdelmalek, B., Davé, R., Bilgili, E., Spray drying of drug-swellable dispersant suspensions for preparation of fast-dissolving, high drug-loaded, surfactant-free nanocomposites. Drug Dev. Ind. Pharm. 41 (2015), 1617–1631.
-
(2015)
Drug Dev. Ind. Pharm.
, vol.41
, pp. 1617-1631
-
-
Azad, M.1
Arteaga, C.2
Abdelmalek, B.3
Davé, R.4
Bilgili, E.5
-
28
-
-
78650677959
-
Spray-freeze-drying production of thermally sensitive polymeric nanoparticle aggregates for inhaled drug delivery: Effect of freeze-drying adjuvants
-
Cheow, W.S., Ng, M.L.L., Kho, K., Hadinoto, K., Spray-freeze-drying production of thermally sensitive polymeric nanoparticle aggregates for inhaled drug delivery: Effect of freeze-drying adjuvants. Int. J. Pharm. 404 (2011), 289–300.
-
(2011)
Int. J. Pharm.
, vol.404
, pp. 289-300
-
-
Cheow, W.S.1
Ng, M.L.L.2
Kho, K.3
Hadinoto, K.4
-
29
-
-
84862776736
-
A comparison between spray drying and spray freeze drying for dry powder inhaler formulation of drug-loaded lipid–polymer hybrid nanoparticles
-
Wang, Y., Kho, K., Cheow, W.S., Hadinoto, K., A comparison between spray drying and spray freeze drying for dry powder inhaler formulation of drug-loaded lipid–polymer hybrid nanoparticles. Int. J. Pharm. 424 (2012), 98–106.
-
(2012)
Int. J. Pharm.
, vol.424
, pp. 98-106
-
-
Wang, Y.1
Kho, K.2
Cheow, W.S.3
Hadinoto, K.4
-
30
-
-
50849113139
-
Effect of polymer molecular weight on nanocomminution of poorly soluble drug
-
Choi, J.-Y., Park, C.H., Lee, J., Effect of polymer molecular weight on nanocomminution of poorly soluble drug. Drug Deliv. 15 (2008), 347–353.
-
(2008)
Drug Deliv.
, vol.15
, pp. 347-353
-
-
Choi, J.-Y.1
Park, C.H.2
Lee, J.3
-
31
-
-
77955980572
-
Effective polymeric dispersants for vacuum, convection and freeze drying of drug nanosuspensions
-
Kim, S., Lee, J., Effective polymeric dispersants for vacuum, convection and freeze drying of drug nanosuspensions. Int. J. Pharm. 397 (2010), 218–224.
-
(2010)
Int. J. Pharm.
, vol.397
, pp. 218-224
-
-
Kim, S.1
Lee, J.2
-
32
-
-
84911487883
-
Enhanced recovery and dissolution of griseofulvin nanoparticles from surfactant-free nanocomposite microparticles incorporating wet-milled swellable dispersants
-
Bhakay, A., Azad, M., Vizzotti, E., Dave, R.N., Bilgili, E., Enhanced recovery and dissolution of griseofulvin nanoparticles from surfactant-free nanocomposite microparticles incorporating wet-milled swellable dispersants. Drug Dev. Ind. Pharm. 40 (2014), 1509–1522.
-
(2014)
Drug Dev. Ind. Pharm.
, vol.40
, pp. 1509-1522
-
-
Bhakay, A.1
Azad, M.2
Vizzotti, E.3
Dave, R.N.4
Bilgili, E.5
-
33
-
-
84995618031
-
A study of the impact of polymer–surfactant in drug nanoparticle coated pharmatose composites on dissolution performance
-
Li, M., Lopez, N., Bilgili, E., A study of the impact of polymer–surfactant in drug nanoparticle coated pharmatose composites on dissolution performance. Adv. Powder Technol. 27 (2016), 1625–1636.
-
(2016)
Adv. Powder Technol.
, vol.27
, pp. 1625-1636
-
-
Li, M.1
Lopez, N.2
Bilgili, E.3
-
34
-
-
69749103682
-
Nanocrystal technology, drug delivery and clinical applications
-
Junghanns, J.-U.A., Müller, R.H., Nanocrystal technology, drug delivery and clinical applications. Int. J. Nanomedicine, 3, 2008, 295.
-
(2008)
Int. J. Nanomedicine
, vol.3
, pp. 295
-
-
Junghanns, J.-U.A.1
Müller, R.H.2
-
35
-
-
0035937599
-
Nanosuspensions as particulate drug formulations in therapy: Rationale for development and what we can expect for the future
-
Müller, R.H., Jacobs, C., Kayser, O., Nanosuspensions as particulate drug formulations in therapy: Rationale for development and what we can expect for the future. Adv. Drug Deliver. Rev. 47 (2001), 3–19.
-
(2001)
Adv. Drug Deliver. Rev.
, vol.47
, pp. 3-19
-
-
Müller, R.H.1
Jacobs, C.2
Kayser, O.3
-
36
-
-
0035095847
-
Characterization of glass solutions of poorly water-soluble drugs produced by melt extrusion with hydrophilic amorphous polymers
-
Forster, A., Hempenstall, J., Rades, T., Characterization of glass solutions of poorly water-soluble drugs produced by melt extrusion with hydrophilic amorphous polymers. J. Pharm. Pharmacol. 53 (2001), 303–315.
-
(2001)
J. Pharm. Pharmacol.
, vol.53
, pp. 303-315
-
-
Forster, A.1
Hempenstall, J.2
Rades, T.3
-
37
-
-
1142303337
-
What is the true solubility advantage for amorphous pharmaceuticals?
-
Hancock, B.C., Parks, M., What is the true solubility advantage for amorphous pharmaceuticals?. Pharm. Res. 17 (2000), 397–404.
-
(2000)
Pharm. Res.
, vol.17
, pp. 397-404
-
-
Hancock, B.C.1
Parks, M.2
-
38
-
-
84857506982
-
Assessing the performance of amorphous solid dispersions
-
Newman, A., Knipp, G., Zografi, G., Assessing the performance of amorphous solid dispersions. J. Pharm. Sci. 101 (2012), 1355–1377.
-
(2012)
J. Pharm. Sci.
, vol.101
, pp. 1355-1377
-
-
Newman, A.1
Knipp, G.2
Zografi, G.3
-
39
-
-
84974782878
-
Effect of polymer type and drug dose on the in vitro and in vivo behavior of amorphous solid dispersions
-
Knopp, M.M., Chourak, N., Khan, F., Wendelboe, J., Langguth, P., Rades, T., Holm, R., Effect of polymer type and drug dose on the in vitro and in vivo behavior of amorphous solid dispersions. Eur. J. Pharm. Biopharm. 105 (2016), 106–114.
-
(2016)
Eur. J. Pharm. Biopharm.
, vol.105
, pp. 106-114
-
-
Knopp, M.M.1
Chourak, N.2
Khan, F.3
Wendelboe, J.4
Langguth, P.5
Rades, T.6
Holm, R.7
-
40
-
-
84884167198
-
Amorphous solid dispersions and nano-crystal technologies for poorly water-soluble drug delivery
-
Brough, C., Williams, R.O. III, Amorphous solid dispersions and nano-crystal technologies for poorly water-soluble drug delivery. Int. J. Pharm. 453 (2013), 157–166.
-
(2013)
Int. J. Pharm.
, vol.453
, pp. 157-166
-
-
Brough, C.1
Williams, R.O.2
-
41
-
-
1142297630
-
Characterization of curcumin–PVP solid dispersion obtained by spray drying
-
Paradkar, A., Ambike, A.A., Jadhav, B.K., Mahadik, K.R., Characterization of curcumin–PVP solid dispersion obtained by spray drying. Int. J. Pharm. 271 (2004), 281–286.
-
(2004)
Int. J. Pharm.
, vol.271
, pp. 281-286
-
-
Paradkar, A.1
Ambike, A.A.2
Jadhav, B.K.3
Mahadik, K.R.4
-
42
-
-
84862897078
-
Mechanistic insights into the dissolution of spray-dried amorphous solid dispersions
-
Langham, Z.A., Booth, J., Hughes, L.P., Reynolds, G.K., Wren, S.A.C., Mechanistic insights into the dissolution of spray-dried amorphous solid dispersions. J. Pharm. Sci. 101 (2012), 2798–2810.
-
(2012)
J. Pharm. Sci.
, vol.101
, pp. 2798-2810
-
-
Langham, Z.A.1
Booth, J.2
Hughes, L.P.3
Reynolds, G.K.4
Wren, S.A.C.5
-
43
-
-
84879030527
-
Improving the physical stability of freeze-dried amorphous sugar matrices by compression at several hundreds MPa
-
Kagotani, R., Kinugawa, K., Nomura, M., Imanaka, H., Ishida, N., Imamura, K., Improving the physical stability of freeze-dried amorphous sugar matrices by compression at several hundreds MPa. J. Pharm. Sci. 102 (2013), 2187–2197.
-
(2013)
J. Pharm. Sci.
, vol.102
, pp. 2187-2197
-
-
Kagotani, R.1
Kinugawa, K.2
Nomura, M.3
Imanaka, H.4
Ishida, N.5
Imamura, K.6
-
44
-
-
77951261150
-
Systematic investigation of the effect of lyophilizate collapse on pharmaceutically relevant proteins I: stability after freeze-drying
-
Schersch, K., Betz, O., Garidel, P., Muehlau, S., Bassarab, S., Winter, G., Systematic investigation of the effect of lyophilizate collapse on pharmaceutically relevant proteins I: stability after freeze-drying. J. Pharm. Sci. 99 (2010), 2256–2278.
-
(2010)
J. Pharm. Sci.
, vol.99
, pp. 2256-2278
-
-
Schersch, K.1
Betz, O.2
Garidel, P.3
Muehlau, S.4
Bassarab, S.5
Winter, G.6
-
45
-
-
84886126076
-
Laminar dispersive and distributive mixing with dissolution and applications to hot-melt extrusion
-
D. Douroumis John Wiley & Sons Inc. Hoboken
-
Gogos, C.G., Liu, H., Wang, P., Laminar dispersive and distributive mixing with dissolution and applications to hot-melt extrusion. Douroumis, D., (eds.) Hot-Melt Extrusion: Pharmaceutical Applications, 2012, John Wiley & Sons Inc., Hoboken, 261–284.
-
(2012)
Hot-Melt Extrusion: Pharmaceutical Applications
, pp. 261-284
-
-
Gogos, C.G.1
Liu, H.2
Wang, P.3
-
46
-
-
34648812679
-
Pharmaceutical applications of hot-melt extrusion: part I
-
Crowley, M.M., Zhang, F., Repka, M.A., Thumma, S., Upadhye, S.B., Kumar Battu, S., McGinity, J.W., Martin, C., Pharmaceutical applications of hot-melt extrusion: part I. Drug Dev. Ind. Pharm. 33 (2007), 909–926.
-
(2007)
Drug Dev. Ind. Pharm.
, vol.33
, pp. 909-926
-
-
Crowley, M.M.1
Zhang, F.2
Repka, M.A.3
Thumma, S.4
Upadhye, S.B.5
Kumar Battu, S.6
McGinity, J.W.7
Martin, C.8
-
47
-
-
84988433448
-
Fast dissolution of poorly water soluble drugs from fluidized bed coated nanocomposites: impact of carrier size
-
Azad, M., Moreno, J., Bilgili, E., Davé, R., Fast dissolution of poorly water soluble drugs from fluidized bed coated nanocomposites: impact of carrier size. Int. J. Pharm. 513 (2016), 319–331.
-
(2016)
Int. J. Pharm.
, vol.513
, pp. 319-331
-
-
Azad, M.1
Moreno, J.2
Bilgili, E.3
Davé, R.4
-
48
-
-
0346494421
-
G.V.d. Mooter, Increased physical stability and improved dissolution properties of itraconazole, a class II drug, by solid dispersions that combine fast- and slow-dissolving polymers
-
Six, K., Verreck, G., Peeters, J., Brewster, M., G.V.d. Mooter, Increased physical stability and improved dissolution properties of itraconazole, a class II drug, by solid dispersions that combine fast- and slow-dissolving polymers. J. Pharm. Sci. 93 (2004), 124–131.
-
(2004)
J. Pharm. Sci.
, vol.93
, pp. 124-131
-
-
Six, K.1
Verreck, G.2
Peeters, J.3
Brewster, M.4
-
49
-
-
0032851619
-
Enhanced solubility and dissolution rate of itraconazole by a solid dispersion technique
-
Jung, J.-Y., Yoo, S.D., Lee, S.-H., Kim, K.-H., Yoon, D.-S., Lee, K.-H., Enhanced solubility and dissolution rate of itraconazole by a solid dispersion technique. Int. J. Pharm. 187 (1999), 209–218.
-
(1999)
Int. J. Pharm.
, vol.187
, pp. 209-218
-
-
Jung, J.-Y.1
Yoo, S.D.2
Lee, S.-H.3
Kim, K.-H.4
Yoon, D.-S.5
Lee, K.-H.6
-
50
-
-
84879088781
-
Nano-extrusion: a one-step process for manufacturing of solid nanoparticle formulations directly from the liquid phase
-
Khinast, J., Baumgartner, R., Roblegg, E., Nano-extrusion: a one-step process for manufacturing of solid nanoparticle formulations directly from the liquid phase. AAPS PharmSciTech 14 (2013), 601–604.
-
(2013)
AAPS PharmSciTech
, vol.14
, pp. 601-604
-
-
Khinast, J.1
Baumgartner, R.2
Roblegg, E.3
-
51
-
-
84908282097
-
Nano-extrusion: a promising tool for continuous manufacturing of solid nano-formulations
-
Baumgartner, R., Eitzlmayr, A., Matsko, N., Tetyczka, C., Khinast, J., Roblegg, E., Nano-extrusion: a promising tool for continuous manufacturing of solid nano-formulations. Int. J. Pharm. 477 (2014), 1–11.
-
(2014)
Int. J. Pharm.
, vol.477
, pp. 1-11
-
-
Baumgartner, R.1
Eitzlmayr, A.2
Matsko, N.3
Tetyczka, C.4
Khinast, J.5
Roblegg, E.6
-
52
-
-
84889087859
-
New investigation of distribution imaging and content uniformity of very low dose drugs using hot-melt extrusion method
-
Park, J.-B., Kang, C.-Y., Kang, W.-S., Choi, H.-G., Han, H.-K., Lee, B.-J., New investigation of distribution imaging and content uniformity of very low dose drugs using hot-melt extrusion method. Int. J. Pharm. 458 (2013), 245–253.
-
(2013)
Int. J. Pharm.
, vol.458
, pp. 245-253
-
-
Park, J.-B.1
Kang, C.-Y.2
Kang, W.-S.3
Choi, H.-G.4
Han, H.-K.5
Lee, B.-J.6
-
53
-
-
84959126662
-
Conjugation of hot-melt extrusion with high-pressure homogenization: a novel method of continuously preparing nanocrystal solid dispersions
-
Ye, X., Patil, H., Feng, X., Tiwari, R.V., Lu, J., Gryczke, A., Kolter, K., Langley, N., Majumdar, S., Neupane, D., Conjugation of hot-melt extrusion with high-pressure homogenization: a novel method of continuously preparing nanocrystal solid dispersions. AAPS PharmSciTech 17 (2015), 78–88.
-
(2015)
AAPS PharmSciTech
, vol.17
, pp. 78-88
-
-
Ye, X.1
Patil, H.2
Feng, X.3
Tiwari, R.V.4
Lu, J.5
Gryczke, A.6
Kolter, K.7
Langley, N.8
Majumdar, S.9
Neupane, D.10
-
54
-
-
77951538902
-
Combining HME & solubilization: soluplus®—the solid solution
-
Hardung, H., Djuric, D., Ali, S., Combining HME & solubilization: soluplus®—the solid solution. Drug Deliv. Technol. 10 (2010), 20–27.
-
(2010)
Drug Deliv. Technol.
, vol.10
, pp. 20-27
-
-
Hardung, H.1
Djuric, D.2
Ali, S.3
-
55
-
-
84906327570
-
A fast and reliable empirical approach for estimating solubility of crystalline drugs in polymers for hot melt extrusion formulations
-
Kyeremateng, S.O., Pudlas, M., Woehrle, G.H., A fast and reliable empirical approach for estimating solubility of crystalline drugs in polymers for hot melt extrusion formulations. J. Pharm. Sci. 103 (2014), 2847–2858.
-
(2014)
J. Pharm. Sci.
, vol.103
, pp. 2847-2858
-
-
Kyeremateng, S.O.1
Pudlas, M.2
Woehrle, G.H.3
-
56
-
-
84911949824
-
Improving the API dissolution rate during pharmaceutical hot-melt extrusion I: effect of the API particle size, and the co-rotating, twin-screw extruder screw configuration on the API dissolution rate
-
Li, M., Gogos, C.G., Ioannidis, N., Improving the API dissolution rate during pharmaceutical hot-melt extrusion I: effect of the API particle size, and the co-rotating, twin-screw extruder screw configuration on the API dissolution rate. Int. J. Pharm. 478 (2015), 103–112.
-
(2015)
Int. J. Pharm.
, vol.478
, pp. 103-112
-
-
Li, M.1
Gogos, C.G.2
Ioannidis, N.3
-
57
-
-
84869487988
-
A combined microhydrodynamics–polymer adsorption analysis for elucidation of the roles of stabilizers in wet stirred media milling
-
Bilgili, E., Afolabi, A., A combined microhydrodynamics–polymer adsorption analysis for elucidation of the roles of stabilizers in wet stirred media milling. Int. J. Pharm. 439 (2012), 193–206.
-
(2012)
Int. J. Pharm.
, vol.439
, pp. 193-206
-
-
Bilgili, E.1
Afolabi, A.2
-
58
-
-
84960347736
-
Is the combination of cellulosic polymers and anionic surfactants a good strategy for ensuring physical stability of BCS Class II drug nanosuspensions?
-
Bilgili, E., Li, M., Afolabi, A., Is the combination of cellulosic polymers and anionic surfactants a good strategy for ensuring physical stability of BCS Class II drug nanosuspensions?. Pharm. Dev. Technol. 21 (2016), 499–510.
-
(2016)
Pharm. Dev. Technol.
, vol.21
, pp. 499-510
-
-
Bilgili, E.1
Li, M.2
Afolabi, A.3
-
59
-
-
0000221422
-
E. sz. Kovats, True surface areas from nitrogen adsorption experiments
-
Jelinek, L., E. sz. Kovats, True surface areas from nitrogen adsorption experiments. Langmuir 10 (1994), 4225–4231.
-
(1994)
Langmuir
, vol.10
, pp. 4225-4231
-
-
Jelinek, L.1
-
60
-
-
84877929703
-
Continuous production of drug nanoparticle suspensions via wet stirred media milling: a fresh look at the Rehbinder effect
-
Monteiro, A., Afolabi, A., Bilgili, E., Continuous production of drug nanoparticle suspensions via wet stirred media milling: a fresh look at the Rehbinder effect. Drug Dev. Ind. Pharm. 39 (2013), 266–283.
-
(2013)
Drug Dev. Ind. Pharm.
, vol.39
, pp. 266-283
-
-
Monteiro, A.1
Afolabi, A.2
Bilgili, E.3
-
61
-
-
26244468421
-
Powder Sampling and Particle Size Determination
-
first ed. Elsevier Amsterdam
-
Allen, T., Powder Sampling and Particle Size Determination. first ed., 2003, Elsevier, Amsterdam.
-
(2003)
-
-
Allen, T.1
-
62
-
-
34548193292
-
The dynamics of capillary flow
-
Washburn, E.W., The dynamics of capillary flow. Phys. Rev., 17, 1921, 273.
-
(1921)
Phys. Rev.
, vol.17
, pp. 273
-
-
Washburn, E.W.1
-
63
-
-
64549133839
-
An investigation on wetting of porous materials
-
Hołownia, D., Kwiatkowska, I., Hupka, J., An investigation on wetting of porous materials. Physicochem. Probl. Mi. 42 (2008), 251–262.
-
(2008)
Physicochem. Probl. Mi.
, vol.42
, pp. 251-262
-
-
Hołownia, D.1
Kwiatkowska, I.2
Hupka, J.3
-
64
-
-
0023195932
-
A simple equation for description of solute release I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs
-
Ritger, P.L., Peppas, N.A., A simple equation for description of solute release I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. J. Control. Release 5 (1987), 23–36.
-
(1987)
J. Control. Release
, vol.5
, pp. 23-36
-
-
Ritger, P.L.1
Peppas, N.A.2
-
65
-
-
0023196815
-
A simple equation for description of solute release II. Fickian and anomalous release from swellable devices
-
Ritger, P.L., Peppas, N.A., A simple equation for description of solute release II. Fickian and anomalous release from swellable devices. J. Control. Release 5 (1987), 37–42.
-
(1987)
J. Control. Release
, vol.5
, pp. 37-42
-
-
Ritger, P.L.1
Peppas, N.A.2
-
66
-
-
84879009609
-
Prediction of drug–polymer miscibility through the use of solubility parameter based flory–huggins interaction parameter and the experimental validation: PEG as model polymer
-
Thakral, S., Thakral, N.K., Prediction of drug–polymer miscibility through the use of solubility parameter based flory–huggins interaction parameter and the experimental validation: PEG as model polymer. J. Pharm. Sci. 102 (2013), 2254–2263.
-
(2013)
J. Pharm. Sci.
, vol.102
, pp. 2254-2263
-
-
Thakral, S.1
Thakral, N.K.2
-
67
-
-
77953296607
-
Drug–polymer solubility and miscibility: Stability consideration and practical challenges in amorphous solid dispersion development
-
Qian, F., Huang, J., Hussain, M.A., Drug–polymer solubility and miscibility: Stability consideration and practical challenges in amorphous solid dispersion development. J. Pharm. Sci. 99 (2010), 2941–2947.
-
(2010)
J. Pharm. Sci.
, vol.99
, pp. 2941-2947
-
-
Qian, F.1
Huang, J.2
Hussain, M.A.3
-
68
-
-
39049103837
-
Understanding a relaxation behavior in a nanoparticle suspension for drug delivery applications
-
Deng, Z., Xu, S., Li, S., Understanding a relaxation behavior in a nanoparticle suspension for drug delivery applications. Int. J. Pharm. 351 (2008), 236–243.
-
(2008)
Int. J. Pharm.
, vol.351
, pp. 236-243
-
-
Deng, Z.1
Xu, S.2
Li, S.3
-
69
-
-
57749206650
-
Estimation of drug–polymer miscibility and solubility in amorphous solid dispersions using experimentally determined interaction parameters
-
Marsac, P.J., Li, T., Taylor, L.S., Estimation of drug–polymer miscibility and solubility in amorphous solid dispersions using experimentally determined interaction parameters. Pharm. Res. 26 (2009), 139–151.
-
(2009)
Pharm. Res.
, vol.26
, pp. 139-151
-
-
Marsac, P.J.1
Li, T.2
Taylor, L.S.3
-
70
-
-
0037074108
-
The mechanisms of drug release from solid dispersions in water-soluble polymers
-
Craig, D.Q., The mechanisms of drug release from solid dispersions in water-soluble polymers. Int. J. Pharm. 231 (2002), 131–144.
-
(2002)
Int. J. Pharm.
, vol.231
, pp. 131-144
-
-
Craig, D.Q.1
-
71
-
-
0032726595
-
Solubility parameters as predictors of miscibility in solid dispersions
-
Greenhalgh, D.J., Williams, A.C., Timmins, P., York, P., Solubility parameters as predictors of miscibility in solid dispersions. J. Pharm. Sci. 88 (1999), 1182–1190.
-
(1999)
J. Pharm. Sci.
, vol.88
, pp. 1182-1190
-
-
Greenhalgh, D.J.1
Williams, A.C.2
Timmins, P.3
York, P.4
-
72
-
-
0028698291
-
Estimation of Hansen solubility parameters for (hydroxyethyl) and (hydroxypropyl) cellulose through molecular simulation
-
Choi, P., Kavassalis, T.A., Rudin, A., Estimation of Hansen solubility parameters for (hydroxyethyl) and (hydroxypropyl) cellulose through molecular simulation. Ind. Eng. Chem. Res. 33 (1994), 3154–3159.
-
(1994)
Ind. Eng. Chem. Res.
, vol.33
, pp. 3154-3159
-
-
Choi, P.1
Kavassalis, T.A.2
Rudin, A.3
-
73
-
-
85020470011
-
-
Hot-Melt Extrusion with BASF Pharma Polymers: Extrusion Compendium, second ed., BASF, Ludwigshafen
-
K. Kolter, M. Karl, A. Gryczke, B. Ludwigshafen am Rhein, Hot-Melt Extrusion with BASF Pharma Polymers: Extrusion Compendium, second ed., BASF, Ludwigshafen, 2012.
-
(2012)
-
-
Kolter, K.1
Karl, M.2
Gryczke, A.3
Ludwigshafen am Rhein, B.4
-
74
-
-
61349191553
-
Enhancement of oral bioavailability of an HIV-attachment inhibitor by nanosizing and amorphous formulation approaches
-
Fakes, M.G., Vakkalagadda, B.J., Qian, F., Desikan, S., Gandhi, R.B., Lai, C., Hsieh, A., Franchini, M.K., Toale, H., Brown, J., Enhancement of oral bioavailability of an HIV-attachment inhibitor by nanosizing and amorphous formulation approaches. Int. J. Pharm. 370 (2009), 167–174.
-
(2009)
Int. J. Pharm.
, vol.370
, pp. 167-174
-
-
Fakes, M.G.1
Vakkalagadda, B.J.2
Qian, F.3
Desikan, S.4
Gandhi, R.B.5
Lai, C.6
Hsieh, A.7
Franchini, M.K.8
Toale, H.9
Brown, J.10
-
75
-
-
84889089518
-
Increased dissolution and oral absorption of itraconazole/Soluplus extrudate compared with itraconazole nanosuspension
-
Zhang, K., Yu, H., Luo, Q., Yang, S., Lin, X., Zhang, Y., Tian, B., Tang, X., Increased dissolution and oral absorption of itraconazole/Soluplus extrudate compared with itraconazole nanosuspension. Eur. J. Pharm. Biopharm. 85 (2013), 1285–1292.
-
(2013)
Eur. J. Pharm. Biopharm.
, vol.85
, pp. 1285-1292
-
-
Zhang, K.1
Yu, H.2
Luo, Q.3
Yang, S.4
Lin, X.5
Zhang, Y.6
Tian, B.7
Tang, X.8
-
76
-
-
84255167486
-
Selection of oral bioavailability enhancing formulations during drug discovery
-
Zheng, W., Jain, A., Papoutsakis, D., Dannenfelser, R.-M., Panicucci, R., Garad, S., Selection of oral bioavailability enhancing formulations during drug discovery. Drug Dev. Ind. Pharm. 38 (2012), 235–247.
-
(2012)
Drug Dev. Ind. Pharm.
, vol.38
, pp. 235-247
-
-
Zheng, W.1
Jain, A.2
Papoutsakis, D.3
Dannenfelser, R.-M.4
Panicucci, R.5
Garad, S.6
-
77
-
-
84958972505
-
Influence of polymer molecular weight on in vitro dissolution behavior and in vivo performance of celecoxib:PVP amorphous solid dispersions
-
Knopp, M.M., Nguyen, J.H., Becker, C., Francke, N.M., Jørgensen, E.B., Holm, P., Holm, R., Mu, H., Rades, T., Langguth, P., Influence of polymer molecular weight on in vitro dissolution behavior and in vivo performance of celecoxib:PVP amorphous solid dispersions. Eur. J. Pharm. Biopharm. 101 (2016), 145–151.
-
(2016)
Eur. J. Pharm. Biopharm.
, vol.101
, pp. 145-151
-
-
Knopp, M.M.1
Nguyen, J.H.2
Becker, C.3
Francke, N.M.4
Jørgensen, E.B.5
Holm, P.6
Holm, R.7
Mu, H.8
Rades, T.9
Langguth, P.10
-
78
-
-
52949150391
-
Effect of polymer type on the dissolution profile of amorphous solid dispersions containing felodipine
-
Konno, H., Handa, T., Alonzo, D.E., Taylor, L.S., Effect of polymer type on the dissolution profile of amorphous solid dispersions containing felodipine. Eur. J. Pharm. Biopharm. 70 (2008), 493–499.
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.70
, pp. 493-499
-
-
Konno, H.1
Handa, T.2
Alonzo, D.E.3
Taylor, L.S.4
-
79
-
-
77956882799
-
Nanocrystals: industrially feasible multifunctional formulation technology for poorly soluble actives
-
Shegokar, R., Müller, R.H., Nanocrystals: industrially feasible multifunctional formulation technology for poorly soluble actives. Int. J. Pharm. 399 (2010), 129–139.
-
(2010)
Int. J. Pharm.
, vol.399
, pp. 129-139
-
-
Shegokar, R.1
Müller, R.H.2
-
80
-
-
84911435123
-
Analyzing the impact of different excipients on drug release behavior in hot-melt extrusion formulations using FTIR spectroscopic imaging
-
Pudlas, M., Kyeremateng, S.O., Williams, L.A.M., Kimber, J.A., van Lishaut, H., Kazarian, S.G., Woehrle, G.H., Analyzing the impact of different excipients on drug release behavior in hot-melt extrusion formulations using FTIR spectroscopic imaging. Eur. J. Pharm. Sci. 67 (2015), 21–31.
-
(2015)
Eur. J. Pharm. Sci.
, vol.67
, pp. 21-31
-
-
Pudlas, M.1
Kyeremateng, S.O.2
Williams, L.A.M.3
Kimber, J.A.4
van Lishaut, H.5
Kazarian, S.G.6
Woehrle, G.H.7
-
81
-
-
84862304361
-
Improving the chemical stability of amorphous solid dispersion with cocrystal technique by hot melt extrusion
-
Liu, X., Lu, M., Guo, Z., Huang, L., Feng, X., Wu, C., Improving the chemical stability of amorphous solid dispersion with cocrystal technique by hot melt extrusion. Pharm. Res. 29 (2012), 806–817.
-
(2012)
Pharm. Res.
, vol.29
, pp. 806-817
-
-
Liu, X.1
Lu, M.2
Guo, Z.3
Huang, L.4
Feng, X.5
Wu, C.6
-
82
-
-
84867401371
-
Dissolution enhancement of poorly water-soluble APIs processed by hot-melt extrusion using hydrophilic polymers
-
Maniruzzaman, M., Rana, M., Boateng, J., Mitchell, J., Douroumis, D., Dissolution enhancement of poorly water-soluble APIs processed by hot-melt extrusion using hydrophilic polymers. Drug Dev. Ind. Pharm. 39 (2013), 218–227.
-
(2013)
Drug Dev. Ind. Pharm.
, vol.39
, pp. 218-227
-
-
Maniruzzaman, M.1
Rana, M.2
Boateng, J.3
Mitchell, J.4
Douroumis, D.5
-
83
-
-
84924032886
-
Investigation of drug–excipient interactions in lapatinib amorphous solid dispersions using solid-state NMR spectroscopy
-
Song, Y., Yang, X., Chen, X., Nie, H., Byrn, S., Lubach, J.W., Investigation of drug–excipient interactions in lapatinib amorphous solid dispersions using solid-state NMR spectroscopy. Mol. Pharm. 12 (2015), 857–866.
-
(2015)
Mol. Pharm.
, vol.12
, pp. 857-866
-
-
Song, Y.1
Yang, X.2
Chen, X.3
Nie, H.4
Byrn, S.5
Lubach, J.W.6
-
84
-
-
0020539240
-
Mechanisms of solute release from porous hydrophilic polymers
-
Korsmeyer, R.W., Gurny, R., Doelker, E., Buri, P., Peppas, N.A., Mechanisms of solute release from porous hydrophilic polymers. Int. J. Pharm. 15 (1983), 25–35.
-
(1983)
Int. J. Pharm.
, vol.15
, pp. 25-35
-
-
Korsmeyer, R.W.1
Gurny, R.2
Doelker, E.3
Buri, P.4
Peppas, N.A.5
-
85
-
-
0021904208
-
Analysis of Fickian and non-Fickian drug release from polymers
-
Peppas, N., Analysis of Fickian and non-Fickian drug release from polymers. Pharm. Acta Helv., 60, 1985, 110.
-
(1985)
Pharm. Acta Helv.
, vol.60
, pp. 110
-
-
Peppas, N.1
-
86
-
-
0035073301
-
Lobo, Modeling and comparison of dissolution profiles
-
Costa, P., Sousa, J.M., Lobo, Modeling and comparison of dissolution profiles. Eur. J. Pharm. Sci. 13 (2001), 123–133.
-
(2001)
Eur. J. Pharm. Sci.
, vol.13
, pp. 123-133
-
-
Costa, P.1
Sousa, J.M.2
-
87
-
-
77953171784
-
Understanding the behavior of amorphous pharmaceutical systems during dissolution
-
Alonzo, D.E., Zhang, G.G., Zhou, D., Gao, Y., Taylor, L.S., Understanding the behavior of amorphous pharmaceutical systems during dissolution. Pharm. Res. 27 (2010), 608–618.
-
(2010)
Pharm. Res.
, vol.27
, pp. 608-618
-
-
Alonzo, D.E.1
Zhang, G.G.2
Zhou, D.3
Gao, Y.4
Taylor, L.S.5
-
88
-
-
84897097503
-
Classification of the Crystallization Behavior of Amorphous Active Pharmaceutical Ingredients in Aqueous Environments
-
Van Eerdenbrugh, B., Raina, S., Hsieh, Y.-L., Augustijns, P., Taylor, L., Classification of the Crystallization Behavior of Amorphous Active Pharmaceutical Ingredients in Aqueous Environments. Pharm. Res. 31 (2014), 969–982.
-
(2014)
Pharm. Res.
, vol.31
, pp. 969-982
-
-
Van Eerdenbrugh, B.1
Raina, S.2
Hsieh, Y.-L.3
Augustijns, P.4
Taylor, L.5
-
89
-
-
33846256269
-
Influence of different polymers on the crystallization tendency of molecularly dispersed amorphous felodipine
-
Konno, H., Taylor, L.S., Influence of different polymers on the crystallization tendency of molecularly dispersed amorphous felodipine. J. Pharm. Sci. 95 (2006), 2692–2705.
-
(2006)
J. Pharm. Sci.
, vol.95
, pp. 2692-2705
-
-
Konno, H.1
Taylor, L.S.2
|