-
1
-
-
34250863849
-
Cocrystal or salt: Does it really matter?
-
DOI 10.1021/mp060126o
-
Aakeröy, C.B., Fasulo, M.B., Desper, J., 2007. Cocrystal or salt: Does it really matter? Mol. Pharm. 4, 317-322. (Pubitemid 46983948)
-
(2007)
Molecular Pharmaceutics
, vol.4
, Issue.3
, pp. 317-322
-
-
Aakeroy, C.B.1
Fasulo, M.E.2
Desper, J.3
-
2
-
-
0017158036
-
Enhancement of solubility of drug salts by hydrophilic counterions: Properties of organic salts of an antimalarial drug
-
Agharkar, S., Lindenbaum, S., Higuchi, T., 1976. Enhancement of solubility of drug salts by hydrophilic counterions: properties of organic salts of an antimalarial drug. J. Pharm. Sci. 65, 747-749.
-
(1976)
J. Pharm. Sci.
, vol.65
, pp. 747-749
-
-
Agharkar, S.1
Lindenbaum, S.2
Higuchi, T.3
-
3
-
-
84860442899
-
Polymorphs, salts, and cocrystals: What's in a name?
-
Aitipamula, S., Banerjee, R., Bansal, A.K., Biradha, K., Cheney, M.L., Choudhury, A.R., Desiraju, G.R., Dikundwar, A.G., Dubey, R., Duggirala, N., Ghogale, P.P., Ghosh, S., Goswami, P.K., Goud, N.R., Jetti, R.K.K.R., Karpinski, P., Kaushik, P., Kumar, D., Kumar, V., Moulton, B., Mukherjee, A., Mukherjee, G., Myerson, A.S., Puri, V., Ramanan, A., Rajamannar, T., Reddy, C.M., Rodriguez-Hornedo, M., Rogers, R.D., Row, T.N.G., Sanphui, P., Shan, N., Shete, G., Singh, A., Sun, C.C., Swift, J.A., Thaimattam, R., Thakur, T.S., Thaper, R.K., Thomas, S.P., Tothadi, S., Vangala, V.R., Variankaval, N., Vishweshwar, P., Weyna, D.R., Zaworotko, M.J., 2012. Polymorphs, salts, and cocrystals: what's in a name? Cryst. Growth Des. 12, 2147-2152.
-
(2012)
Cryst. Growth Des.
, vol.12
, pp. 2147-2152
-
-
Aitipamula, S.1
Banerjee, R.2
Bansal, A.K.3
Biradha, K.4
Cheney, M.L.5
Choudhury, A.R.6
Desiraju, G.R.7
Dikundwar, A.G.8
Dubey, R.9
Duggirala, N.10
Ghogale, P.P.11
Ghosh, S.12
Goswami, P.K.13
Goud, N.R.14
Jetti, R.K.K.R.15
Karpinski, P.16
Kaushik, P.17
Kumar, D.18
Kumar, V.19
Moulton, B.20
Mukherjee, A.21
Mukherjee, G.22
Myerson, A.S.23
Puri, V.24
Ramanan, A.25
Rajamannar, T.26
Reddy, C.M.27
Rodriguez-Hornedo, M.28
Rogers, R.D.29
Row, T.N.G.30
Sanphui, P.31
Shan, N.32
Shete, G.33
Singh, A.34
Sun, C.C.35
Swift, J.A.36
Thaimattam, R.37
Thakur, T.S.38
Thaper, R.K.39
Thomas, S.P.40
Tothadi, S.41
Vangala, V.R.42
Variankaval, N.43
Vishweshwar, P.44
Weyna, D.R.45
Zaworotko, M.J.46
more..
-
4
-
-
85030489181
-
Overcoming formulation problems and some case studies
-
Akers, M.J. (Ed.), Informa Healthcare, London
-
Akers, M.J., 2008. Overcoming formulation problems and some case studies. In: Akers, M.J. (Ed.), Sterile Drug Products. Formulation, Packaging, Manufacturing and Quality. Informa Healthcare, London, pp. 169-179.
-
(2008)
Sterile Drug Products. Formulation, Packaging, Manufacturing and Quality
, pp. 169-179
-
-
Akers, M.J.1
-
5
-
-
0001056344
-
Preparation of water soluble compounds through salt formation
-
Wermuth, C.G. (Ed.), Academic Press, London
-
Anderson, B.D., Flora, K.P., 1996. Preparation of water soluble compounds through salt formation. In: Wermuth, C.G. (Ed.), The Practices of Medicinal Chemistry. Academic Press, London, pp. 739-754.
-
(1996)
The Practices of Medicinal Chemistry
, pp. 739-754
-
-
Anderson, B.D.1
Flora, K.P.2
-
6
-
-
0026457856
-
Sustained propranolol delivert and increased oral bioavailability in dogs given a propranolol laurate salt
-
Aungst, B.J., Hussain, M.A., 1992. Sustained propranolol delivert and increased oral bioavailability in dogs given a propranolol laurate salt. Pharm. Res. 9, 1107-1109.
-
(1992)
Pharm. Res.
, vol.9
, pp. 1107-1109
-
-
Aungst, B.J.1
Hussain, M.A.2
-
7
-
-
53049103992
-
The co-crystal approach to improve the exposure of a water-insoluble compound. AMG 517 Sorbic acid co-crystal characterization and pharmacokinetics
-
Bak, A., Gore, A., Yanez, E., Stanton, M., Tuekcic, S., Syed, R., Akrami, A., Rose, M., Surapenini, S., Bostick, T., King, A., Neervannan, S., Ostovic, D., Koparkar, A., 2008. The co-crystal approach to improve the exposure of a water-insoluble compound. AMG 517 Sorbic acid co-crystal characterization and pharmacokinetics. J. Pharm. Sci. 97, 3942-3956.
-
(2008)
J. Pharm. Sci.
, vol.97
, pp. 3942-3956
-
-
Bak, A.1
Gore, A.2
Yanez, E.3
Stanton, M.4
Tuekcic, S.5
Syed, R.6
Akrami, A.7
Rose, M.8
Surapenini, S.9
Bostick, T.10
King, A.11
Neervannan, S.12
Ostovic, D.13
Koparkar, A.14
-
8
-
-
27744484364
-
Saccharin salts of active pharmaceutical ingredients, their crystal structures, and increased water solubilities
-
DOI 10.1021/cg050125l
-
Banerjeree, R., Bhatt, P.M., Ravindra, N.V., Desiraju, G.R., 2005. Saccharin salts of active pharmaceutical ingredients, their crystal structures and increased water solubilities. Cryst. Growth Des. 5, 2299-2309. (Pubitemid 41619324)
-
(2005)
Crystal Growth and Design
, vol.5
, Issue.6
, pp. 2299-2309
-
-
Banerjee, R.1
Bhatt, P.M.2
Ravindra, N.V.3
Desiraju, G.R.4
-
9
-
-
0034345216
-
Salt selection and optimisation for pharmaceutical new chemical entities
-
Bastin, R.J., Bowker, M.J., Slater, B.J., 2000. Salt selection and optimisation for pharmaceutical new chemical entities. Org. Proc. Res. Dev. 4, 427-435.
-
(2000)
Org. Proc. Res. Dev.
, vol.4
, pp. 427-435
-
-
Bastin, R.J.1
Bowker, M.J.2
Slater, B.J.3
-
10
-
-
0017623487
-
Pharmaceutical salts
-
Berge, S.M., Bighley, L.D., Monkhouse, D.C., 1977a. Pharmaceutical salts. J. Pharm. Sci. 66, 1-19.
-
(1977)
J. Pharm. Sci.
, vol.66
, pp. 1-19
-
-
Berge, S.M.1
Bighley, L.D.2
Monkhouse, D.C.3
-
12
-
-
0001736698
-
Salts
-
Swarbrick, J., Boylan, J.C. (Eds.), Marcell-Decker, Inc, New York
-
Bighley, L.D., Berge, S.M., Monkhouse, D.C., 1995. Salts. In: Swarbrick, J., Boylan, J.C. (Eds.), Encyclopedia of Pharmaceutical Technology, vol. 13. Marcell-Decker, Inc, New York, pp. 453-499.
-
(1995)
Encyclopedia of Pharmaceutical Technology
, vol.13
, pp. 453-499
-
-
Bighley, L.D.1
Berge, S.M.2
Monkhouse, D.C.3
-
13
-
-
0017623487
-
Pharmacautical salts
-
Berge, S.M., Bighley, L.M., Monkhouse, D.C., 1977b. Pharmacautical salts. J. Pharm. Sci. 66, 1-19.
-
(1977)
J. Pharm. Sci.
, vol.66
, pp. 1-19
-
-
Berge, S.M.1
Bighley, L.M.2
Monkhouse, D.C.3
-
14
-
-
0015591509
-
Effect of complexation with phenobarbital on the biologic availability of theophyline from three tablet formulastions
-
Bettis, J.W., Lach, J.L., Hood, J., 1973. Effect of complexation with phenobarbital on the biologic availability of theophyline from three tablet formulastions. Am. J. Hosp. Pharm. 30, 240-243.
-
(1973)
Am. J. Hosp. Pharm.
, vol.30
, pp. 240-243
-
-
Bettis, J.W.1
Lach, J.L.2
Hood, J.3
-
15
-
-
34249088975
-
Structure, solubility, screening, and synthesis of molecular salts
-
DOI 10.1002/jps.20927
-
Black, S.N., Collier, E.A., Davey, R.J., Roberts, R.J., 2007. Structure, solubility, screening and synthesis of molecular salts. J. Pharm. Sci. 96, 1053-1068. (Pubitemid 46797476)
-
(2007)
Journal of Pharmaceutical Sciences
, vol.96
, Issue.5
, pp. 1053-1068
-
-
Black, S.N.1
Collier, E.A.2
Davey, R.J.3
Roberts, R.J.4
-
16
-
-
0029070763
-
Pharmaceutical solids-a strategic approach to regulatory considerations
-
Byrn, S., Pfeiffer, R., Ganey, M., Hoiberg, C., Poochikian, G., 1995. Pharmaceutical solids-a strategic approach to regulatory considerations. Pharm. Res. 12, 945-954.
-
(1995)
Pharm. Res.
, vol.12
, pp. 945-954
-
-
Byrn, S.1
Pfeiffer, R.2
Ganey, M.3
Hoiberg, C.4
Poochikian, G.5
-
17
-
-
0013218013
-
The absolute configuration of sertraline (Zoloft) hydrochloride
-
Caruso, F., Besmer, A., Rossi, M., 1999. The absolute configuration of sertraline (Zoloft) hydrochloride. Acta Cryst. C 55, 1712.
-
(1999)
Acta Cryst. C
, vol.55
, pp. 1712
-
-
Caruso, F.1
Besmer, A.2
Rossi, M.3
-
18
-
-
33846233108
-
Development of a pharmaceutical cocrystal of a monophosphate salt with phosphoric acid
-
DOI 10.1039/b612353h
-
Chen, A.M., Ellison, M.E., Perespykin, A.V., Wenslow, R.M., Variankaval, N., Savarin, C.G., Natishan, T.K., Mathre, D.J., Dormer, P.G., Euler, D.H., Ye, Z., Wang, Y., Santos, I., 2007. Development of a pharmaceutical cocrystal of a monophosphate salt with phosphoric acid. Chem. Comm. 4, 419-421. (Pubitemid 46105535)
-
(2007)
Chemical Communications
, Issue.4
, pp. 419-421
-
-
Chen, A.M.1
Ellison, M.E.2
Peresypkin, A.3
Wenslow, R.M.4
Variankaval, N.5
Savarin, C.G.6
Natishan, T.K.7
Mathre, D.J.8
Dormer, P.G.9
Euler, D.H.10
Ball, R.G.11
Ye, Z.12
Wang, Y.13
Santos, I.14
-
19
-
-
0025239647
-
Reduction of dimethyl sulfoxide by dihydrohalide salts of pharmaceuticals
-
DOI 10.1016/0378-5173(90)90111-G
-
Chen, T.K., Thornton, D., Ho, M.Y.K., 1990. Reduction of dimethylsulfoxide by dihydrohalide salts of pharmaceuticals. Int. J. Pharm. 59, 211-216. (Pubitemid 20146152)
-
(1990)
International Journal of Pharmaceutics
, vol.59
, Issue.3
, pp. 211-216
-
-
Chen, T.K.1
Thornton, D.2
Ho, M.Y.K.3
-
20
-
-
74049153760
-
Effects of crystal form on solubility and pharmacokinetics: A crystal engineering case study of lamotrigine
-
Cheney, M.L., Shan, N., Healey, E.R., Hannan, M., Wojtas, L., Zaworotko, M.J., Sava, V., Song, S., Sanchez-Ramos, J.R., 2010. Effects of crystal form on solubility and pharmacokinetics: A crystal engineering case study of lamotrigine. Cryst. Growth Des. 10, 394-405.
-
(2010)
Cryst. Growth Des.
, vol.10
, pp. 394-405
-
-
Cheney, M.L.1
Shan, N.2
Healey, E.R.3
Hannan, M.4
Wojtas, L.5
Zaworotko, M.J.6
Sava, V.7
Song, S.8
Sanchez-Ramos, J.R.9
-
21
-
-
58149242453
-
Aqueous versus non-aqueous salt delivery strategies to enhance oral bioavailability of a mitogen-activated protein kinase-activated protein kinase (MK-2) inhibitor in rats
-
Chiang, P.-C., South, S.A., Daniels, J.S., Anderson, D.R., Wene, S.P., Albin, L.A., Mourey, R.J., Selbo, J.G., 2009. Aqueous versus non-aqueous salt delivery strategies to enhance oral bioavailability of a mitogen-activated protein kinase-activated protein kinase (MK-2) inhibitor in rats. J. Pharm. Sci. 98, 248-256.
-
(2009)
J. Pharm. Sci.
, vol.98
, pp. 248-256
-
-
Chiang, P.-C.1
South, S.A.2
Daniels, J.S.3
Anderson, D.R.4
Wene, S.P.5
Albin, L.A.6
Mourey, R.J.7
Selbo, J.G.8
-
22
-
-
6044264984
-
Crystal engineering approach to forming cocrystals of amine hydrochlorides with organic acids. Molecular complexes of fluoxetine hydrochloride with benzoic, succinic, and fumaric acids
-
Childs, S.L., Chyall, L.J., Dunlap, J.T., Smolenskaya, V.N., Stahly, B.C., Stahly, P.J., 2004 Crystal engineering approach to forming cocrystals of amine hydrochlorides with organic acids. Molecular complexes of fluoxetine hydrochloride with benzoic, succinic, and fumaric acids. J. Am. Chem. Soc. 126, 13335-13342.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 13335-13342
-
-
Childs, S.L.1
Chyall, L.J.2
Dunlap, J.T.3
Smolenskaya, V.N.4
Stahly, B.C.5
Stahly, P.J.6
-
23
-
-
34547486346
-
Cocrystals of piroxicam with carboxylic acids
-
Childs, S.L., Hardcastle, K.I., 2007. Cocrystals of piroxicam with carboxylic acids. Cryst. Growth Des. 7, 1291-1304.
-
(2007)
Cryst. Growth Des.
, vol.7
, pp. 1291-1304
-
-
Childs, S.L.1
Hardcastle, K.I.2
-
24
-
-
34250791543
-
The salt-cocrystal continuum: The influence of crystal structure on ionization state
-
DOI 10.1021/mp0601345
-
Childs, S.L., Stahly, G.P., Park, A., 2007. The salt-cocrystal continuum: The influence of crystal structure on ionization state. Mol. Pharm. 4, 323-338. (Pubitemid 46983949)
-
(2007)
Molecular Pharmaceutics
, vol.4
, Issue.3
, pp. 323-338
-
-
Childs, S.L.1
Stahly, G.P.2
Park, A.3
-
25
-
-
65249151820
-
Analysis of 50 crystal structures containing carbamezapine using the Materials module of Mercury CSD
-
Childs, S.L., Wood, P.A., Rodriguez-Hornedo, N., Reddy, L.S., Hardcastle, K.I., 2009. Analysis of 50 crystal structures containing carbamezapine using the Materials module of Mercury CSD. Crsyt. Growth Des. 9, 1869-1888.
-
(2009)
Crsyt. Growth Des.
, vol.9
, pp. 1869-1888
-
-
Childs, S.L.1
Wood, P.A.2
Rodriguez-Hornedo, N.3
Reddy, L.S.4
Hardcastle, K.I.5
-
26
-
-
82455188322
-
Impact of the counterion on the solubility and physicochemical properties of salts of carboxylic acid salts
-
David, S.E., Timmins, P., Conway, B.R., 2012. Impact of the counterion on the solubility and physicochemical properties of salts of carboxylic acid salts. Drug Dev. Ind. Pharm. 38, 93-103.
-
(2012)
Drug Dev. Ind. Pharm.
, vol.38
, pp. 93-103
-
-
David, S.E.1
Timmins, P.2
Conway, B.R.3
-
27
-
-
0347471246
-
High-throughput screening techniques for pre-formulation: Salt-selection and polymorph studies, scientific updates
-
Desrosiers, P., 2001. High-throughput screening techniques for pre-formulation: Salt-selection and polymorph studies, scientific updates. International Symposium on Polymorphism and Crystallization.
-
(2001)
International Symposium on Polymorphism and Crystallization
-
-
Desrosiers, P.1
-
28
-
-
10744231772
-
High-throughput screening techniques for pre-formulation: Salt-selection and polymorph studies
-
Desrosiers, P., Carlson, E., Chandler, W., Chau, H., Cong, P., Doolen, R., Freitag, C., Lin, S., Masui, C., Wu, E., Crevier, T., Mullins, D., Song, L., Lou, R., Zhan, J., Tangkilisan, A., Ung, Q., Phan, K., 2002. High-throughput screening techniques for pre-formulation: Salt-selection and polymorph studies. Acta Cryst. A, 58, (C9 Supplement).
-
(2002)
Acta Cryst. A
, vol.58
, Issue.C9 SUPPL.
-
-
Desrosiers, P.1
Carlson, E.2
Chandler, W.3
Chau, H.4
Cong, P.5
Doolen, R.6
Freitag, C.7
Lin, S.8
Masui, C.9
Wu, E.10
Crevier, T.11
Mullins, D.12
Song, L.13
Lou, R.14
Zhan, J.15
Tangkilisan, A.16
Ung, Q.17
Phan, K.18
-
29
-
-
0033805179
-
In vitro-in vivo correlation for lipophilic poorly water soluble drugs
-
Dressman, J.B., Repas, C., 2000. In vitro-in vivo correlation for lipophilic poorly water soluble drugs. Eur. J. Pharm. Sci. 11, S73-S80.
-
(2000)
Eur. J. Pharm. Sci.
, vol.11
-
-
Dressman, J.B.1
Repas, C.2
-
30
-
-
77953318934
-
The utility of sulfonate salts in drug development
-
Elder, D.P., Delaney, E., Teasedale, A., Eyley, S., Reif Van, D., Jacq, K., Facchine, K.L., Oestrich, R., Sandra, P., David, F., 2010. The utility of sulfonate salts in drug development. J. Pharm. Sci. 99, 2948-2961.
-
(2010)
J. Pharm. Sci.
, vol.99
, pp. 2948-2961
-
-
Elder, D.P.1
Delaney, E.2
Teasedale, A.3
Eyley, S.4
Reif Van, D.5
Jacq, K.6
Facchine, K.L.7
Oestrich, R.8
Sandra, P.9
David, F.10
-
32
-
-
84860456003
-
-
FDA, US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER)
-
FDA, 2011. US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER). Guidance for Industry: Regulatory Classification of Pharmaceutical Cocrystals.
-
(2011)
Guidance for Industry: Regulatory Classification of Pharmaceutical Cocrystals
-
-
-
33
-
-
61649108172
-
Effect of the counterion on the solubility on isostructural pharmaceutical lamotrigine salts
-
Galcera, J., Mollins, E., 2009. Effect of the counterion on the solubility on isostructural pharmaceutical lamotrigine salts. Cryst. Growth Des. 9, 327-334.
-
(2009)
Cryst. Growth Des.
, vol.9
, pp. 327-334
-
-
Galcera, J.1
Mollins, E.2
-
34
-
-
8844219708
-
Drugs as materials: Valuing physical form in drug discovery
-
DOI 10.1038/nrd1550
-
Gardner, C.R., Walsh, C.T., Almarrson, O., 2004. Drugs as materials: Valuing physical form in drug discovery. Nat. Rev. Drug Disc. 3, 926-934. (Pubitemid 39529930)
-
(2004)
Nature Reviews Drug Discovery
, vol.3
, Issue.11
, pp. 926-934
-
-
Gardner, C.R.1
Walsh, C.T.2
Almarsson, O.3
-
35
-
-
66249101601
-
Solubility advantage of pharmaceutical cocrystals
-
Good, D.J., Rodríguez-Hornedo, N., 2009. Solubility advantage of pharmaceutical cocrystals. Cryst. Growth Des. 9, 2252-2264.
-
(2009)
Cryst. Growth Des.
, vol.9
, pp. 2252-2264
-
-
Good, D.J.1
Rodríguez-Hornedo, N.2
-
36
-
-
0023032232
-
Salt selection for basic drugs
-
DOI 10.1016/0378-5173(86)90055-4
-
Gould, P.L., 1986. Salt selection for basic drugs. Int. J. Pharm. 33, 201-217. (Pubitemid 17197805)
-
(1986)
International Journal of Pharmaceutics
, vol.33
, Issue.1-3
, pp. 201-217
-
-
Gould, P.L.1
-
37
-
-
39049163486
-
An approach to early phase salt selection: Application to NBI-75043
-
Gross, T.D., Schaab, K., Ouellette, M., Zook, S., Reddy, J.P., Schurtleff, A., Sacaan, T.A., Alebic-Kolbah, I., Bozigan, H., 2007. An approach to early phase salt selection: Application to NBI-75043. Org. Proc. Res. Dev. 11, 365-377.
-
(2007)
Org. Proc. Res. Dev.
, vol.11
, pp. 365-377
-
-
Gross, T.D.1
Schaab, K.2
Ouellette, M.3
Zook, S.4
Reddy, J.P.5
Schurtleff, A.6
Sacaan, T.A.7
Alebic-Kolbah, I.8
Bozigan, H.9
-
38
-
-
0023253722
-
Preformulation salt selection. Physical property comparisons of the tris(hydroxymethyl)aminomethane (THAM) salts of four analgesic/antiinflammatory agents with the sodium salts and the free acids
-
Gu, L., Strickley, R.G., 1987. Preformulation salt selection. Physical property comparisions of the tris(hydroxymethyl)aminomethane (THAM) salts of 4 analgesic anti-inflammatory agents with sodium salts and the free acids. Pharm. Res., 4, 255-257. (Pubitemid 17110403)
-
(1987)
Pharmaceutical Research
, vol.4
, Issue.3
, pp. 255-257
-
-
Gu, L.1
Strickley, R.G.2
-
39
-
-
35348987129
-
Combined use of crystalline forms and precipitation inhibitors to improve oral absorption of celecoxib from solid oral formulations
-
Guzmán, H.R., Tawa, M., Zhang, Z., Ratabanangkoon, P., Shaw, P., Gardner, C.R., Moreau, J P., Almarrson, Ö., Remenar, J.F., 2007. Combined use of crystalline forms and precipitation inhibitors to improve oral absorption of celecoxib from solid oral formulations. J. Pharm. Sci. 96, 2686-2700.
-
(2007)
J. Pharm. Sci.
, vol.96
, pp. 2686-2700
-
-
Guzmán, H.R.1
Tawa, M.2
Zhang, Z.3
Ratabanangkoon, P.4
Shaw, P.5
Gardner, C.R.6
Moreau, J.P.7
Almarrson, Ö.8
Remenar, J.F.9
-
40
-
-
0030638567
-
Characterization and significance of the amorphous state in pharmaceutical systems
-
Hancock, B.C., Zografi, G., 1997. Characterization and significance of the amorphous state in pharmaceutical systems. J. Pharm. Sci. 86, 1-12.
-
(1997)
J. Pharm. Sci.
, vol.86
, pp. 1-12
-
-
Hancock, B.C.1
Zografi, G.2
-
41
-
-
33846945738
-
Escitalopram oxalate: Co-existence of oxalate dianions and oxalic acid molecules in the same crystal
-
Harrison, W.T.A., Yathirajan, H.S., Bindya, S., Anilkumar, H.G., Devaraju, 2007. Escitalopram oxalate: co-existence of oxalate dianions and oxalic acid molecules in the same crystal. Acta Cryst. C 63, 129-131.
-
(2007)
Acta Cryst. C
, vol.63
, pp. 129-131
-
-
Harrison, W.T.A.1
Yathirajan, H.S.2
Bindya, S.3
Anilkumar, H.G.4
Devaraju5
-
42
-
-
65249109747
-
Discovering new co-crystals
-
ter Horst, J.H., Deiji, M.A., Cains, P.W., 2009. Discovering new co-crystals. Cryst. Growth Des. 9, 1531-1537.
-
(2009)
Cryst. Growth Des.
, vol.9
, pp. 1531-1537
-
-
Ter Horst, J.H.1
Deiji, M.A.2
Cains, P.W.3
-
43
-
-
84884141953
-
Good manufacturing practice guide for active pharmaceutical ingredients
-
ICH Q7A, 10 November 2000
-
ICH Q7A, 2000. Good manufacturing practice guide for active pharmaceutical ingredients, ICH Harmonized Tripartite Guidance, 10 November 2000.
-
(2000)
ICH Harmonized Tripartite Guidance
-
-
-
44
-
-
0004139082
-
-
Krieger Publishing Company, Malabar
-
Jacques, J., Collet, A., Willen, S., 1991. Enantiomers, Racemates, and Resolutions. Krieger Publishing Company, Malabar.
-
(1991)
Enantiomers, Racemates, and Resolutions
-
-
Jacques, J.1
Collet, A.2
Willen, S.3
-
46
-
-
79951895459
-
Salts of hydrates of imiquimod, an immune response modifier
-
Kumar, T.L., Vishweshar, P., Babu, J.M., Vyas, K., 2009. Salts of hydrates of imiquimod, an immune response modifier. Cryst. Growth Des. 9, 4822-4829.
-
(2009)
Cryst. Growth Des.
, vol.9
, pp. 4822-4829
-
-
Kumar, T.L.1
Vishweshar, P.2
Babu, J.M.3
Vyas, K.4
-
47
-
-
40949126942
-
Salt selection in drug development
-
Kumar, L., Amin, A., Bansal, A.K., 2008. Salt selection in drug development. Pharm. Technol., 128-146.
-
(2008)
Pharm. Technol.
, pp. 128-146
-
-
Kumar, L.1
Amin, A.2
Bansal, A.K.3
-
48
-
-
0036279842
-
Form IV of carbamazepine
-
DOI 10.1002/jps.10093
-
Lang, M., Kampf, J.W., Matzger, A.J., 2002. Form IV of carbamazepine. J. Pharm. Sci. 91, 1186-1190. (Pubitemid 34640943)
-
(2002)
Journal of Pharmaceutical Sciences
, vol.91
, Issue.4
, pp. 1186-1190
-
-
Lang, M.1
Kampf, J.W.2
Matzger, A.J.3
-
49
-
-
74849101611
-
Large scale aspects of salt formation: Processing of intermediates and final products
-
Stahl, P.H., Wermuth, G. (Eds.), Wiley-VCH, Weinheim
-
Lee, S., Hoff, C., 2002. Large scale aspects of salt formation: processing of intermediates and final products. In: Stahl, P.H., Wermuth, G. (Eds.), Handbook of Pharmaceutical Salts; Properties, Selection and Use. Wiley-VCH, Weinheim, pp. 191-220.
-
(2002)
Handbook of Pharmaceutical Salts; Properties, Selection and Use
, pp. 191-220
-
-
Lee, S.1
Hoff, C.2
-
50
-
-
0034601240
-
Improving drug solubility for oral delivery using solid dispersions
-
DOI 10.1016/S0939-6411(00)00076-X, PII S093964110000076X
-
Leuner, C., Dressman, J., 2000. Improving drug solubility for oral delivery using solid dispersions. Eur. J. Pharm. Biopharm. 50, 47-60. (Pubitemid 30326688)
-
(2000)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.50
, Issue.1
, pp. 47-60
-
-
Leuner, C.1
Dressman, J.2
-
51
-
-
23844475290
-
Effect of chloride ion on dissolution of different salt forms of haloperidol, a model basic drug
-
DOI 10.1002/jps.20440
-
Li, S., Doyle, P., Metz, S., Royce, A.E., Serajuddin, A.T.M., 2005. Effect of chloride ion on dissolution of different salt forms of haloperidol, a model basic drug. J. Pharm. Sci. 94, 2224-2231. (Pubitemid 41665282)
-
(2005)
Journal of Pharmaceutical Sciences
, vol.94
, Issue.10
, pp. 2224-2231
-
-
Li, S.1
Doyle, P.2
Metz, S.3
Royce, A.E.4
Serajuddin, A.T.M.5
-
52
-
-
33745660776
-
15N NMR spectroscopy
-
DOI 10.1021/ja0541332
-
Li, Z.J., Abramov, Y., Bordner, J., Leonard, J., Medek, A., Trask, A.V., 2006. Solidstate acid-base interactions in complexes of heterocyclic bases with dicarboxylic acids: crystallography, hydrogen bond analysis, and 15N NMR spectroscopy. J. Am. Chem. Soc. 128, 8199-8210. (Pubitemid 43967764)
-
(2006)
Journal of the American Chemical Society
, vol.128
, Issue.25
, pp. 8199-8210
-
-
Li, Z.J.1
Abramov, Y.2
Bordner, J.3
Leonard, J.4
Medek, A.5
Trask, A.V.6
-
53
-
-
0015402055
-
Preformulation investigations I: Relation of salt forms and biological activity of an experimental antihypertensive
-
Lin, S-L., Lachman, L., Swartz, C.J., Huebner, C.F., 1972. Preformulation investigations I: Relation of salt forms and biological activity of an experimental antihypertensive. J. Pharm. Sci. 61, 1418-1422.
-
(1972)
J. Pharm. Sci.
, vol.61
, pp. 1418-1422
-
-
Lin, S.-L.1
Lachman, L.2
Swartz, C.J.3
Huebner, C.F.4
-
54
-
-
0030927353
-
Characterization of fluids from the stomach and proximal jejunum in men and women
-
DOI 10.1023/A:1012107801889
-
Lindahl, A., Ungell, A.L., Lennernas, H., 1997. Characterization of the fluids from the stomach and proximal jejunum in men and women. Pharm. Res. 14, 497-502. (Pubitemid 27205011)
-
(1997)
Pharmaceutical Research
, vol.14
, Issue.4
, pp. 497-502
-
-
Lindahl, A.1
Ungell, A.-L.2
Knutson, L.3
Lennernas, H.4
-
55
-
-
0034461768
-
Drug-like properties and the causes of poor solubility and poor permeability
-
DOI 10.1016/S1056-8719(00)00107-6, PII S1056871900001076
-
Lipinski, C.A., 2000. Drug-like properties and the causes of poor solubility and permeability. J. Pharmacol. Toxicol. Meth. 44, 235-249. (Pubitemid 32239479)
-
(2000)
Journal of Pharmacological and Toxicological Methods
, vol.44
, Issue.1
, pp. 235-249
-
-
Lipinski, C.A.1
-
56
-
-
30344440543
-
Solubility in water and DMSO: Issues and potential solutions
-
Borchardt, R.T., Kerns, E.H., Lipinski, C.A., Thakker, D.R., Wang, B. (Eds.), AAPS Press, Arlington, Virginia
-
Lipinski, C.A., 2004. Solubility in water and DMSO: Issues and potential solutions. In: Borchardt, R.T., Kerns, E.H., Lipinski, C.A., Thakker, D.R., Wang, B. (Eds.), Pharmaceutical Profiling in Drug Discovery for Lead Selection. AAPS Press, Arlington, Virginia, pp. 93-125.
-
(2004)
Pharmaceutical Profiling in Drug Discovery for Lead Selection
, pp. 93-125
-
-
Lipinski, C.A.1
-
57
-
-
80053505508
-
Coamorphous drug systems: Enhanced physical stability and dissolution rate of indomethacin and naproxen
-
Löbmann, K., Laitinen, R., Grohganz, H., Gordan, K.C., Strachan, C., Rades, T., 2011. Coamorphous drug systems: Enhanced physical stability and dissolution rate of indomethacin and naproxen. Mol. Pharm. 8, 1919-1928.
-
(2011)
Mol. Pharm.
, vol.8
, pp. 1919-1928
-
-
Löbmann, K.1
Laitinen, R.2
Grohganz, H.3
Gordan, K.C.4
Strachan, C.5
Rades, T.6
-
58
-
-
84861092839
-
Coamorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions
-
Löbmann, K., Strachan, C., Grohganz, H., Rades, T., Korhonen, O., Laitinen, R., 2012. Coamorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions. Eur. J. Pharm. Biopharm. 81, 159-169.
-
(2012)
Eur. J. Pharm. Biopharm.
, vol.81
, pp. 159-169
-
-
Löbmann, K.1
Strachan, C.2
Grohganz, H.3
Rades, T.4
Korhonen, O.5
Laitinen, R.6
-
60
-
-
80052963861
-
Computational prediction of salt and cocrystal structures-Does a proton position matter?
-
Mohamed, S., Tocher, D.A., Price, S.L., 2011. Computational prediction of salt and cocrystal structures-Does a proton position matter? Int. J. Pharm. 418, 187-198.
-
(2011)
Int. J. Pharm.
, vol.418
, pp. 187-198
-
-
Mohamed, S.1
Tocher, D.A.2
Price, S.L.3
-
61
-
-
1042298890
-
High-throughput crystallization: Polymorphs, salts, co-crystals and solvates of pharmaceutical solids
-
DOI 10.1016/j.addr.2003.10.020
-
Morissettee, S.L., Almarsson, Ö., Peterson, M.L., Remenar, J.L., Read, M.J., Lemmo, A.V., Ellis, S., Cima, M.J., Gardner, C.R., 2004. High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids. Adv. Drug Del. Rev. 56, 275-300. (Pubitemid 38201426)
-
(2004)
Advanced Drug Delivery Reviews
, vol.56
, Issue.3
, pp. 275-300
-
-
Morissette, S.L.1
Almarsson, O.2
Peterson, M.L.3
Remenar, J.F.4
Read, M.J.5
Lemmo, A.V.6
Ellis, S.7
Cima, M.J.8
Gardner, C.R.9
-
62
-
-
85030497802
-
High-throughput crystallization of polymorphs and salts: Application in early lead optimization
-
Abstracts of Papers (MEDI-301)
-
Morissettee, S.L., Read, M.J., Soukasene, S., Tauber, M., Scopettulo, L., Apgar, J., Guzman, H., Sauer, J., Collins, D., Jadhav, P.K., Engler, T., Gardner, C.R., 2003. High-throughput crystallization of polymorphs and salts: Application in early lead optimization, Abstracts of Papers (MEDI-301), 225th ACS National Meeting, New Orleans LA, United States, March pp. 23-27.
-
(2003)
225th ACS National Meeting, New Orleans LA, United States, March
, pp. 23-27
-
-
Morissettee, S.L.1
Read, M.J.2
Soukasene, S.3
Tauber, M.4
Scopettulo, L.5
Apgar, J.6
Guzman, H.7
Sauer, J.8
Collins, D.9
Jadhav, P.K.10
Engler, T.11
Gardner, C.R.12
-
63
-
-
0028219710
-
An integrated approach to the selection of optimal salt form for a new drug candidate
-
Morris, K.R., Fakes, M.G., Thakur, A.B., Newman, A.W., Singh, A.K., Venit, J.J., Spagnuolo, C.J., Serajuddin, A.T.M., 1994. An integrated approach to the selection of optimal salt form for a new drug candidate. Int. J. Pharm. 105, 209-217.
-
(1994)
Int. J. Pharm.
, vol.105
, pp. 209-217
-
-
Morris, K.R.1
Fakes, M.G.2
Thakur, A.B.3
Newman, A.W.4
Singh, A.K.5
Venit, J.J.6
Spagnuolo, C.J.7
Serajuddin, A.T.M.8
-
64
-
-
0035897679
-
Theoretical approaches to physical transformations of active pharmaceutical ingredients during manufacturing processes
-
DOI 10.1016/S0169-409X(01)00100-4, PII S0169409X01001004
-
Morris, K.R., Griesser, U.J., Eckhardt, C.J., Stowell, J.G., 2001. Theoretical approaches to physical transformations of active pharmaceutical ingredients during manufacturing processes. Adv. Drug Del. Rev. 48, 91-114. (Pubitemid 32452293)
-
(2001)
Advanced Drug Delivery Reviews
, vol.48
, Issue.1
, pp. 91-114
-
-
Morris, K.R.1
Griesser, U.J.2
Eckhardt, C.J.3
Stowell, J.G.4
-
65
-
-
79957979325
-
Polymorphs, pseudopolymorphs, and co-crystals of orcinol: Exploring the structural landcape with high throughput crystallography
-
Mukherjee, A., Grobelny, P., Thakur, T.S., Desiraju, G.R., 2011. Polymorphs, pseudopolymorphs, and co-crystals of orcinol: Exploring the structural landcape with high throughput crystallography. Cryst. Growth Des. 11, 2637-2653.
-
(2011)
Cryst. Growth Des.
, vol.11
, pp. 2637-2653
-
-
Mukherjee, A.1
Grobelny, P.2
Thakur, T.S.3
Desiraju, G.R.4
-
66
-
-
0002642747
-
Theorie der reaktionsgeschwindigkeit in heterogenen systemen
-
Nernst, W., 1904. Theorie der reaktionsgeschwindigkeit in heterogenen systemen. Z. Phys. Chem. 47, 52-55.
-
(1904)
Z. Phys. Chem.
, vol.47
, pp. 52-55
-
-
Nernst, W.1
-
67
-
-
15744376252
-
Electron and nuclear positions in the short hydrogen bond in urotropine-N-oxide-formic acid
-
DOI 10.1021/jp047187r
-
Nygren, C.L., Wilson, C.C., Turner, J.F.C., 2005. Electron and nuclear positions in the short hydrogen bond in utropine-N-oxide-formic acid. J. Phys. Chem. A 109, 1911-1919. (Pubitemid 40406841)
-
(2005)
Journal of Physical Chemistry A
, vol.109
, Issue.9
, pp. 1911-1919
-
-
Nygren, C.L.1
Wilson, C.C.2
Turner, J.F.C.3
-
68
-
-
0035845754
-
Preparation and characterisation of a range of diclofenac salts
-
DOI 10.1016/S0378-5173(01)00800-6, PII S0378517301008006
-
O'Connor, K.M., Corrigan, O.W., 2001. Preparation and characterization of a range of diclofenac salts. Int. J. Pharm. 226, 163-179. (Pubitemid 32800791)
-
(2001)
International Journal of Pharmaceutics
, vol.226
, Issue.1-2
, pp. 163-179
-
-
O'Connor, K.M.1
Corrigan, O.I.2
-
69
-
-
53549097633
-
Discovery of a stable molecular complex of an API with HCl: A long journey to a conventional salt
-
Peresypkin, A.V., Variankaval, N., Ferlita, R., Wenslow, R.M., Smitrovich, J., Thomposon, K., Murry, J., Crocker, L., Mathre, D.J., Wang, Y., Harmon, P., Ellison, M., Song, S., Makarov, A., Helmy, R., 2007. Discovery of a stable molecular complex of an API with HCl: A long journey to a conventional salt. J. Pharm. Sci. 9, 3721-3726.
-
(2007)
J. Pharm. Sci.
, vol.9
, pp. 3721-3726
-
-
Peresypkin, A.V.1
Variankaval, N.2
Ferlita, R.3
Wenslow, R.M.4
Smitrovich, J.5
Thomposon, K.6
Murry, J.7
Crocker, L.8
Mathre, D.J.9
Wang, Y.10
Harmon, P.11
Ellison, M.12
Song, S.13
Makarov, A.14
Helmy, R.15
-
70
-
-
70349636200
-
Rapid conversion of API hydrates to anhydrous forms in aqueous media
-
Petrova, R.I., Peresypkin, A., Mortko, C.J., McKeown, A.E., Lee, J., Williams, M., 2009. Rapid conversion of API hydrates to anhydrous forms in aqueous media. J. Pharm. Sci. 98, 4111-4118.
-
(2009)
J. Pharm. Sci.
, vol.98
, pp. 4111-4118
-
-
Petrova, R.I.1
Peresypkin, A.2
Mortko, C.J.3
McKeown, A.E.4
Lee, J.5
Williams, M.6
-
71
-
-
20344391910
-
Trends in solubility of polymorphs
-
DOI 10.1002/jps.20302
-
Pudipeddi, M., Serajuddin, A.T.M., 2005. Trends in solubility of polymorphs. J. Pharm. Sci. 94, 929-939. (Pubitemid 40780760)
-
(2005)
Journal of Pharmaceutical Sciences
, vol.94
, Issue.5
, pp. 929-939
-
-
Pudipeddi, M.1
Serajuddin, A.T.M.2
-
72
-
-
33645115596
-
Polymorphism, salts, and crystallization: The relevance of solid state development
-
Raumer, V.M., Dannappel, J., Hilfiker, R., 2006. Polymorphism, salts, and crystallization: the relevance of solid state development. Chem. Today 24, 41-44.
-
(2006)
Chem. Today
, vol.24
, pp. 41-44
-
-
Raumer, V.M.1
Dannappel, J.2
Hilfiker, R.3
-
73
-
-
0346104829
-
Salt Selection and Simultaneous Polymorphism Assessment via High-Throughput Crystallization: The Case of Sertraline
-
DOI 10.1021/op034115+
-
Remenar, J.F., MacPhee, J.M., Larsen, B.K., Tyagi, V.A., Ho, J.H., McIlror, D.A., Hickey, M.B., Shaw, P.B., Almarsson, O., 2003a. Salt selection and simultaneous polymorph assessment via high throughput crystallisation: the case of sertraline. Org. Proc. Res. Dev. 7, 990-996. (Pubitemid 37543828)
-
(2003)
Organic Process Research and Development
, vol.7
, Issue.6
, pp. 990-996
-
-
Remenar, J.F.1
MacPhee, J.M.2
Larson, B.K.3
Tyagi, V.A.4
Ho, J.H.5
McIlroy, D.A.6
Hickey, M.B.7
Shaw, P.B.8
Almarsson, O.9
-
74
-
-
0038713880
-
Crystal engineering of novel cocrystals of a triazole drug with 1,4-dicarboxylic acids
-
DOI 10.1021/ja035776p
-
Remenar, J.F., Morissettee, S.L., Peterson, M.L., Moulton, B., MacPhee, J.M., Almarsson, Ö., 2003. Crystal engineering of novel cocrystals of a triazole drug with 1,4-dicarboxylic acids. J. Am. Chem. Soc. 125, 8456-8457. (Pubitemid 36858412)
-
(2003)
Journal of the American Chemical Society
, vol.125
, Issue.28
, pp. 8456-8457
-
-
Remenar, J.F.1
Morissette, S.L.2
Peterson, M.L.3
Moulton, B.4
MacPhee, J.M.5
Guzman, H.R.6
Almarsson, O.7
-
75
-
-
65449130073
-
Synthon competition and cooperation in molecular salts of hydroxybenzoic acids and aminopyridines
-
Sarma, B., Nath, N.K., Bhogala, B.R., Nangia, A., 2009. Synthon competition and cooperation in molecular salts of hydroxybenzoic acids and aminopyridines. Cryst. Growth Des. 9, 1546-1557.
-
(2009)
Cryst. Growth Des.
, vol.9
, pp. 1546-1557
-
-
Sarma, B.1
Nath, N.K.2
Bhogala, B.R.3
Nangia, A.4
-
76
-
-
66849083715
-
Pharmaceutical cocrystals and their physicochemical properties
-
Schultheiss, N., Newman, A., 2009. Pharmaceutical cocrystals and their physicochemical properties. Cryst. Growth Des. 9, 2950-2967.
-
(2009)
Cryst. Growth Des.
, vol.9
, pp. 2950-2967
-
-
Schultheiss, N.1
Newman, A.2
-
77
-
-
34548032742
-
Salt formation to improve drug solubility
-
DOI 10.1016/j.addr.2007.05.010, PII S0169409X07000816
-
Serajuddin, A.T.M., 2007. Salt formation to improve drug solubility. Adv. Drug Del. Rev. 59, 603-616. (Pubitemid 47285406)
-
(2007)
Advanced Drug Delivery Reviews
, vol.59
, Issue.7
, pp. 603-616
-
-
Serajuddin, A.T.M.1
-
78
-
-
0032885450
-
Solid dispersions of poorly water soluble drugs: Early promises, subsequent problems and recent breakthroughs
-
Serajuddin, A.T., 1999. Solid dispersions of poorly water soluble drugs: Early promises, subsequent problems and recent breakthroughs. J. Pharm. Sci. 88, 1058-1066.
-
(1999)
J. Pharm. Sci.
, vol.88
, pp. 1058-1066
-
-
Serajuddin, A.T.1
-
79
-
-
0021944082
-
Effect of diffusion layer pH and solubility on the dissolution rate of pharmaceutical acids and their sodium salts II: Salicylic acid, theophylline, and benzoic acid
-
DOI 10.1002/jps.2600740209
-
Serajuddin, A.T.M., Jarowski, C.I., 1985. Effect of diffusion layer pH and solubility on the dissolution rate of pharmaceutical acids and their sodium salts II: salicylic acid, theophyline and benzoic acid. J. Pharm. Sci. 74, 148-154. (Pubitemid 15135800)
-
(1985)
Journal of Pharmaceutical Sciences
, vol.74
, Issue.2
, pp. 148-154
-
-
Serajuddin, A.T.M.1
Jarowski, C.I.2
-
80
-
-
0021946116
-
pH-solubility profiles of organic bases and their hydrochloride salts
-
Serajuddin, A.T.M., Mufson, D., 1985. pH-Solubility profiles of organic bases and their hydrochloride salts. Pharm. Res. 2, 65-68. (Pubitemid 15123844)
-
(1985)
Pharmaceutical Research
, vol.NO. 2
, pp. 65-68
-
-
Serajuddin, A.T.M.1
Mufson, D.2
-
81
-
-
1042284960
-
Salt-Selection Strategies
-
Stahl, P.H., Wermuth, G. (Eds.), Wiley-VCH, Weinheim
-
Serajuddin, A.T.M., Pudipeddi, M., 2002. Salt-Selection Strategies. In: Stahl, P.H., Wermuth, G. (Eds.), Handbook of Pharmaceutical Salts; Properties, Selection and Use. Wiley-VCH, Weinheim, pp. 135-160.
-
(2002)
Handbook of Pharmaceutical Salts; Properties, Selection and Use
, pp. 135-160
-
-
Serajuddin, A.T.M.1
Pudipeddi, M.2
-
82
-
-
0023198501
-
Common ion effect on solubility and the dissolution rate of the sodium salt of an organic acid
-
Serajuddin, A.T.M., Sheen, P.C., Augustine, M.A., 1987. Common ion effect on the solubility and dissolution rate of the sodium salt of an organic acid. J. Pharm. Pharmacol. 39, 587-591. (Pubitemid 17116301)
-
(1987)
Journal of Pharmacy and Pharmacology
, vol.39
, Issue.8
, pp. 587-591
-
-
Serajuddin, A.T.M.1
Sheen, P.-C.2
Augustine, M.A.3
-
83
-
-
68449100594
-
Antidepressants as hydrobromide salts: Are they a cause for concern?
-
Shader, R.I., 2009. Antidepressants as hydrobromide salts: Are they a cause for concern? J. Clin. Pyschopharm. 29, 317-318.
-
(2009)
J. Clin. Pyschopharm.
, vol.29
, pp. 317-318
-
-
Shader, R.I.1
-
84
-
-
84855404945
-
Advances in pharmaceutical co-crystal screening: Effective co-crystal screening through structural resemblance
-
Springuel, G., Norberg, B., Robeyns, K., Wouters, J., Leyssens, T., 2012. Advances in pharmaceutical co-crystal screening: Effective co-crystal screening through structural resemblance. Cryst. Growth Des. 12, 475-484.
-
(2012)
Cryst. Growth Des.
, vol.12
, pp. 475-484
-
-
Springuel, G.1
Norberg, B.2
Robeyns, K.3
Wouters, J.4
Leyssens, T.5
-
85
-
-
1042273375
-
Pharmaceutical aspects of the drug salt form
-
Stahl, P.H., Wermuth, G. (Eds.), Wiley-VCH, Weinheim
-
Stahl, P.H., Nakano, M., 2002. Pharmaceutical aspects of the drug salt form. In: Stahl, P.H., Wermuth, G. (Eds.), Handbook of Pharmaceutical Salts; Properties, Selection and Use. Wiley-VCH, Weinheim, pp. 83-116.
-
(2002)
Handbook of Pharmaceutical Salts; Properties, Selection and Use
, pp. 83-116
-
-
Stahl, P.H.1
Nakano, M.2
-
86
-
-
0042058435
-
-
Wiley-VCH, Weinheim
-
Stahl, P.H., Wermuth, C.G. (Eds.), 2002a. Pharmaceutical Salts: Properties, Selection, and Use. Wiley-VCH, Weinheim.
-
(2002)
Pharmaceutical Salts: Properties, Selection, and Use
-
-
Stahl, P.H.1
Wermuth, C.G.2
-
87
-
-
1042294609
-
Monographs on acids and bases
-
Stahl, P.H., Wermuth, G. (Eds.), Wiley-VCH, Weinheim
-
Stahl, P.H., Wermuth, G., 2002b. Monographs on acids and bases. In: Stahl, P.H., Wermuth, G. (Eds.), Handbook of Pharmaceutical Salts; Properties, Selection and Use. Wiley-VCH, Weinheim, pp. 265-327.
-
(2002)
Handbook of Pharmaceutical Salts; Properties, Selection and Use
, pp. 265-327
-
-
Stahl, P.H.1
Wermuth, G.2
-
88
-
-
34347245300
-
Diversity in single- and multiple-component crystals. The search for and prevalence of polymorphs and co-crystals
-
Stahly, G.P., 2007. Diversity in single- and multiple-component crystals. The search for and prevalence of polymorphs and co-crystals. Cryst. Growth Des. 7, 1007-1026.
-
(2007)
Cryst. Growth Des.
, vol.7
, pp. 1007-1026
-
-
Stahly, G.P.1
-
89
-
-
79955594268
-
Improved pharmacokinetics of AMG 517 through co-crystallization Part 2: Analysis of 12 carboxylic acid co-crystals
-
Stanton, M.K., Kelly, R.C., Colletti, A., Langley, M., Munson, E.J., Peterson, M.L., Roberts, J., Wells, M., 2011. Improved pharmacokinetics of AMG 517 through co-crystallization Part 2: Analysis of 12 carboxylic acid co-crystals. J. Pharm. Sci. 100, 2734-2743.
-
(2011)
J. Pharm. Sci.
, vol.100
, pp. 2734-2743
-
-
Stanton, M.K.1
Kelly, R.C.2
Colletti, A.3
Langley, M.4
Munson, E.J.5
Peterson, M.L.6
Roberts, J.7
Wells, M.8
-
90
-
-
79952224350
-
Physical stability of salts of weak bases in the solid-state
-
Stephenson, G.A., Arurub, A., Woods, T.A., 2011. Physical stability of salts of weak bases in the solid-state. J. Pharm. Sci. 100, 1607-1617.
-
(2011)
J. Pharm. Sci.
, vol.100
, pp. 1607-1617
-
-
Stephenson, G.A.1
Arurub, A.2
Woods, T.A.3
-
91
-
-
67049162360
-
Improved physical stability of amorphous state through acid base interactions
-
Telang, C., Mujumdar, S., Mathew, M., 2009. Improved physical stability of amorphous state through acid base interactions. J. Pharm. Sci. 98, 2149-2159.
-
(2009)
J. Pharm. Sci.
, vol.98
, pp. 2149-2159
-
-
Telang, C.1
Mujumdar, S.2
Mathew, M.3
-
92
-
-
0032815782
-
Solid-state characteristics of amorphous sodium indomethacin relative to its free acid
-
DOI 10.1023/A:1018985110956
-
Tong, P., Zografi, G., 1999. Solid-state characteristics of amorphous sodium indomethacin relative to its free acid. Pharm. Res. 16, 1186-1192. (Pubitemid 29393605)
-
(1999)
Pharmaceutical Research
, vol.16
, Issue.8
, pp. 1186-1192
-
-
Tong, P.1
Zografi, G.2
-
93
-
-
0036001407
-
Influence of alkali metal counterions on the glass transition temperature of amorphous indomethacin salts
-
DOI 10.1023/A:1015310213887
-
Tong, P., Taylor, L.S., Zografi, G., 2002. Influence of alkali metal counterions on the glass transition temperature of amorphous indomethacin salts. Pharm. Res. 19, 649-654. (Pubitemid 34553673)
-
(2002)
Pharmaceutical Research
, vol.19
, Issue.5
, pp. 649-654
-
-
Tong, P.1
Taylor, L.S.2
Zografi, G.3
-
94
-
-
64649101109
-
An investigation into the influence of counterion on the properties of some amorphous organic salts
-
Towler, C.S., Li, T., Wikstrom, H., Remick, D.M., Sanchez-Felix, M.V., Taylor, L.S., 2008. An investigation into the influence of counterion on the properties of some amorphous organic salts. Mol. Pharm. 5, 946-955.
-
(2008)
Mol. Pharm.
, vol.5
, pp. 946-955
-
-
Towler, C.S.1
Li, T.2
Wikstrom, H.3
Remick, D.M.4
Sanchez-Felix, M.V.5
Taylor, L.S.6
-
95
-
-
84857939797
-
Formulation possibilities of a weak base with narrow solubility range
-
Venczel, M., Svoboda, I., Podanyi, B., Valente, D., Menegotto, J., Pintye-Hodi Ujhelyi, G., 2012. Formulation possibilities of a weak base with narrow solubility range. Cryst. Growth Des. 12, 1101-1110.
-
(2012)
Cryst. Growth Des.
, vol.12
, pp. 1101-1110
-
-
Venczel, M.1
Svoboda, I.2
Podanyi, B.3
Valente, D.4
Menegotto, J.5
Pintye-Hodi Ujhelyi, G.6
-
96
-
-
33645371510
-
Pharmaceutical cocrystals
-
Vishweshwar, P., McMahon, J.A., Bis, J.A., Zaworotko, M.J., 2006. Pharmaceutical cocrystals. J. Pharm. Sci. 95, 499-516.
-
(2006)
J. Pharm. Sci.
, vol.95
, pp. 499-516
-
-
Vishweshwar, P.1
McMahon, J.A.2
Bis, J.A.3
Zaworotko, M.J.4
-
97
-
-
1642457350
-
An Automated Approach to Salt Selection for New Unique Trazodone Salts
-
DOI 10.1023/B:PHAM.0000012167.60180.c3
-
Ware, E.C., Lu, D.R., 2005. An automated approach to salt selection for new unique trazodone salts. Pharm. Res. 21, 177-184. (Pubitemid 38122307)
-
(2004)
Pharmaceutical Research
, vol.21
, Issue.1
, pp. 177-184
-
-
Ware, E.C.1
Lu, D.R.2
-
98
-
-
0036267481
-
Hydrolysis in pharmaceutical formulations
-
DOI 10.1081/PDT-120003494
-
Waterman, K.C., Adami, R.C., Alsante, K.M., Antipas, A.S., Arenson, D.R., Carrier, R., Hong, J., Landis, M.S., Lombardo, F., Shah, J.C., Shalaev, E., Smith, S.W., Wang, H., 2002. Hydrolysis in pharmaceutical formulations. Pharm. Dev. Technol. 7, 113-146. (Pubitemid 34600961)
-
(2002)
Pharmaceutical Development and Technology
, vol.7
, Issue.2
, pp. 113-146
-
-
Waterman, K.C.1
Adami, R.C.2
Alsante, K.M.3
Antipas, A.S.4
Arenson, D.R.5
Carrier, R.6
Hong, J.7
Landis, M.S.8
Lombardo, F.9
Shah, J.C.10
Shalaev, E.11
Smith, S.W.12
Wang, H.13
-
99
-
-
20744433869
-
Salt formation in solid dispersions consisting of polyacrylic acid as a carrier and three basic model compounds resulting in very high glass transition temperatures and constant dissolution properties upon storage
-
DOI 10.1016/j.ejps.2005.04.011, PII S0928098705001351
-
Weuts, I., Kempen, D., Verreck, G., Peeters, J., Brewster, M., Blsaton, M., Van den Mooter, G., 2005. Salt formation in solid dispersions consisting of polyacrylic acid as a carrier and three basic model compounds resulting in very high glass transition temperatures and constant dissolution properties upon storage. Eur. J. Pharm. Sci. 25, 387-393. (Pubitemid 40853866)
-
(2005)
European Journal of Pharmaceutical Sciences
, vol.25
, Issue.4-5
, pp. 387-393
-
-
Weuts, I.1
Kempen, D.2
Verreck, G.3
Peeters, J.4
Brewster, M.5
Blaton, N.6
Van Den, M.G.7
-
100
-
-
0035991618
-
Examination of the solubilization of drugs by bile salt micelles
-
DOI 10.1002/jps.10158
-
Wiedmann, T.S., Kamel, L., 2002. Examination of the solubilisation of drugs by bile salt micelles. J. Pharm. Sci. 91, 1743-1764. (Pubitemid 34810521)
-
(2002)
Journal of Pharmaceutical Sciences
, vol.91
, Issue.8
, pp. 1743-1764
-
-
Wiedmann, T.S.1
Kamel, L.2
-
101
-
-
0019166075
-
Solubility and partitioning I. Solubility of nanoelectrolytes in water
-
Yalkowsky, S.H., Valvani, S.C., 1980. Solubility and partitioning I. Solubility of nanoelectrolytes in water. J. Pharm. Sci. 68, 912-922.
-
(1980)
J. Pharm. Sci.
, vol.68
, pp. 912-922
-
-
Yalkowsky, S.H.1
Valvani, S.C.2
-
102
-
-
27744509918
-
Measuring free-energy difference between crystal polymorphs through eutectic melting
-
DOI 10.1021/jp053653g
-
Yu, L., Huang, J., Jones, K.J., 2005. Measuring free energy differences between crystal polymorphs through eutectic melting. J. Phys. Chem. B 109, 19915-19922. (Pubitemid 41598505)
-
(2005)
Journal of Physical Chemistry B
, vol.109
, Issue.42
, pp. 19915-19922
-
-
Yu, L.1
Huang, J.2
Jones, K.J.3
-
103
-
-
34248596026
-
Stabilization of the maleate salt of a basic drug by adjustment of microenvironmental pH in solid dosage form
-
DOI 10.1016/j.ijpharm.2007.01.005, PII S0378517307000178
-
Zannou, E.A., Ji, Q., Joshi, Y.M., Serajuddin, A.T.M., 2007. Stabilization of the maleate salt of a basic drug by adjustment of the microenvironment pH in the solid dosage form. Int. J. Pharm. 337, 210-218. (Pubitemid 46756053)
-
(2007)
International Journal of Pharmaceutics
, vol.337
, Issue.1-2
, pp. 210-218
-
-
Zannou, E.A.1
Ji, Q.2
Joshi, Y.M.3
Serajuddin, A.T.M.4
-
104
-
-
0034936439
-
Dehydration, hydration behavior, and structural analysis of fenoprofen calcium
-
DOI 10.1002/jps.1038
-
Zhu, H., Xu, J., Varlashkin, P., Long, S., Kidd, C., 2001. Dehydration, hydration behaviour and structural analysis of fenoprofen calcium. J. Pharm. Sci. 90, 845-859. (Pubitemid 32645943)
-
(2001)
Journal of Pharmaceutical Sciences
, vol.90
, Issue.7
, pp. 845-859
-
-
Zhu, H.1
Xu, J.2
Varlashkin, P.3
Long, S.4
Kidd, C.5
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