Investigation of preparation parameters of nanosuspension by top-down media milling to improve the dissolution of poorly water-soluble glyburide

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 78, Issue 3, 2011, Pages 441-446

  Singh, Sachin Kumar ^a,e   Srinivasan, K K ^b   Gowthamarajan, K ^c   Singare, Dhananjay S ^d   Prakash, Dev ^a   Gaikwad, Narayan Babulal ^a  

^a KARPAGAM UNIVERSITY   (India)

^b MANIPAL UNIVERSITY   (India)

^c JSS COLLEGE OF PHARMACY   (India)

^d DR REDDY'S LABORATORIES LTD   (India)

^e BHARATHI COLLEGE OF PHARMACY   (India)

Author keywords

Bead mill; Mean particle size d(90); Nanosuspension; Unmilled drug; X ray powder diffraction; Zeta potential

Indexed keywords

GLIBENCLAMIDE;

ANALYSIS OF VARIANCE; ARTICLE; DISSOLUTION; IN VITRO STUDY; PARTICLE SIZE; X RAY DIFFRACTION; ZETA POTENTIAL;

DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG STABILITY; EXCIPIENTS; GLYBURIDE; HYPOGLYCEMIC AGENTS; NANOPARTICLES; PARTICLE SIZE; POLYMERS; POWDERS; SOLUBILITY; SURFACE-ACTIVE AGENTS; SUSPENSIONS;

EID: 79960616705     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.03.014     Document Type: Article

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