Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein

Nature

Volumn 546, Issue 7657, 2017, Pages 248-253

  Zhang, Yan ^a   Sun, Bingfa ^b   Feng, Dan ^b   Hu, Hongli ^a   Chu, Matthew ^b   Qu, Qianhui ^a   Tarrasch, Jeffrey T ^a   Li, Shane ^b   Sun Kobilka, Tong ^b   Kobilka, Brian K ^b,c   Skiniotis, Georgios ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b ConfometRx ^*  (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; G PROTEIN COUPLED RECEPTOR; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCAGON RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

CHEMICAL BINDING; CRYSTAL STRUCTURE; HORMONE; METABOLISM; PEPTIDE; PROTEIN;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; CRYOELECTRON MICROSCOPY; HORMONE BINDING; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; ANIMAL; CHEMISTRY; CLASSIFICATION; LEPORIDAE; METABOLISM; MOLECULAR MODEL; ULTRASTRUCTURE;

ANIMALS; CRYOELECTRON MICROSCOPY; GLUCAGON-LIKE PEPTIDE 1; GLUCAGON-LIKE PEPTIDE-1 RECEPTOR; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; MODELS, MOLECULAR; PROTEIN DOMAINS; RABBITS;

EID: 85020380548     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature22394     Document Type: Article

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