Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

Nature

Volumn 536, Issue 7617, 2016, Pages 484-487

  Venkatakrishnan, A J ^a,b,c   Deupi, Xavier ^d   Lebon, Guillaume ^e,f   Heydenreich, Franziska M ^d,g,h   Flock, Tilman ^a   Miljus, Tamara ^d,g   Balaji, Santhanam ^a   Bouvier, Michel ^h   Veprintsev, Dmitry B ^d,g   Tate, Christopher G ^a   Schertler, Gebhard F X ^d,g   Babu, M Madan ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Stanford University   (United States)

^d PAUL SCHERRER INSTITUTE   (Switzerland)

^e INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

^f UNIV MONTPELLIER   (France)

^g ETH ZURICH   (Switzerland)

^h INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE DIPHOSPHATE; TYROSINE; ARGININE VASOPRESSIN RECEPTOR 2, HUMAN; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND; VASOPRESSIN RECEPTOR;

CHEMICAL BINDING; GENE; GENETIC ANALYSIS; LIGAND; MEMBRANE; PROTEIN;

ARTICLE; HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; BINDING SITE; CHEMISTRY; CLASSIFICATION; CONSERVED SEQUENCE; GENETICS; METABOLISM; MOLECULAR MODEL; PROTEIN SECONDARY STRUCTURE; STRUCTURAL HOMOLOGY;

BINDING SITES; CONSERVED SEQUENCE; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; LIGANDS; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, VASOPRESSIN; SIGNAL TRANSDUCTION; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 84983806015     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature19107     Document Type: Article

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