Residues within the transmembrane domain of the glucagon-like peptide-1 receptor involved in ligand binding and receptor activation: Modelling the ligand-bound receptor

Molecular Endocrinology

Volumn 25, Issue 10, 2011, Pages 1804-1818

  Coopman, K ^a   Wallis, R ^b   Robb, G ^b   Brown, A J H ^b   Wilkinson, G F ^b   Timms, D ^b   Willars, G B ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; EXENDIN 4; G PROTEIN COUPLED RECEPTOR; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; MEMBRANE PROTEIN; OPSIN;

ARTICLE; CRYSTAL STRUCTURE; DRUG POTENCY; HUMAN; HUMAN CELL; LIGAND BINDING; MUTAGENESIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR AFFINITY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACIDS; CYCLIC AMP; GLUCAGON-LIKE PEPTIDE 1; HEK293 CELLS; HUMANS; KINETICS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION; OPSINS; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, GLUCAGON; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; VENOMS;

MAMMALIA;

EID: 80053381451     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2011-1160     Document Type: Article

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