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Volumn 12, Issue 1, 1998, Pages 78-86

Constitutive activity of glucagon receptor mutants

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON RECEPTOR;

EID: 0031892559     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.12.1.0045     Document Type: Article
Times cited : (68)

References (41)
  • 1
    • 0026659679 scopus 로고
    • Glucagon-like peptide-1, a new hormone of the entero-insular axis
    • Ørskov C 1992 Glucagon-like peptide-1, a new hormone of the entero-insular axis. Diabetologia 35:701-711
    • (1992) Diabetologia , vol.35 , pp. 701-711
    • Ørskov, C.1
  • 2
    • 0001794093 scopus 로고    scopus 로고
    • Molecular Structure of G-Protein Coupled Receptors
    • Foreman JC, Johansen T (eds) CRC Press, Boca Raton, FL
    • Schwartz TW 1996 Molecular Structure of G-Protein Coupled Receptors. In: Foreman JC, Johansen T (eds) Textbook of Receptor Pharmacology. CRC Press, Boca Raton, FL, pp 65-84
    • (1996) Textbook of Receptor Pharmacology , pp. 65-84
    • Schwartz, T.W.1
  • 3
    • 0027745212 scopus 로고
    • Receptors for secretin, calcitonin, parathyroid hormone (PTH)/PTH-related peptide, vasoactive intestinal peptide, glucagon-like peptide 1, growth hormone-releasing hormone, and glucagon belong to a newly discovered G-protein-linked receptor family
    • Segre GV, Goldring SR 1993 Receptors for secretin, calcitonin, parathyroid hormone (PTH)/PTH-related peptide, vasoactive intestinal peptide, glucagon-like peptide 1, growth hormone-releasing hormone, and glucagon belong to a newly discovered G-protein-linked receptor family. Trends Endocrinol Metab 4:309-314
    • (1993) Trends Endocrinol Metab , vol.4 , pp. 309-314
    • Segre, G.V.1    Goldring, S.R.2
  • 4
    • 0030482313 scopus 로고    scopus 로고
    • Receptors for VIP, PACAP, secretin, GRF, glucagon, GLP-1, and other members of their new family of G protein-linked receptors: Structure-function relationship with special reference to the human VIP-1 receptor
    • Laburthe M, Couvineau A, Gaudin P, Maoret J-J, Royer-Fessard C, Nicole P 1996 Receptors for VIP, PACAP, secretin, GRF, glucagon, GLP-1, and other members of their new family of G protein-linked receptors: structure-function relationship with special reference to the human VIP-1 receptor. Ann NY Acad Sci 805:94-109
    • (1996) Ann NY Acad Sci , vol.805 , pp. 94-109
    • Laburthe, M.1    Couvineau, A.2    Gaudin, P.3    Maoret, J.-J.4    Royer-Fessard, C.5    Nicole, P.6
  • 6
    • 0029898348 scopus 로고    scopus 로고
    • Is there a lock for all agonist keys in 7TM receptors?
    • Schwartz TW, Rosenkilde MM 1996 Is there a lock for all agonist keys in 7TM receptors? Trends Pharmacol Sci 17:213-216
    • (1996) Trends Pharmacol Sci , vol.17 , pp. 213-216
    • Schwartz, T.W.1    Rosenkilde, M.M.2
  • 9
    • 0028925811 scopus 로고
    • Chimeric human calcitonin and glucagon receptors reveal two dissociable calcitonin interaction sites
    • Stroop, SD, Kuestner, RE, Serwold, TS, Chen, L, Moore, EE 1995 Chimeric human calcitonin and glucagon receptors reveal two dissociable calcitonin interaction sites. Biochemistry 34:1050-1057
    • (1995) Biochemistry , vol.34 , pp. 1050-1057
    • Stroop, S.D.1    Kuestner, R.E.2    Serwold, T.S.3    Chen, L.4    Moore, E.E.5
  • 10
    • 0028987130 scopus 로고
    • Glucagon. glucagon-like peptide I receptor chimeras reveal domains that determine specificity of glucagon binding
    • Buggy JJ, Livingston JN, Rabin DU, Yoo-Warren H 1995 Glucagon. glucagon-like peptide I receptor chimeras reveal domains that determine specificity of glucagon binding. J Biol Chem 270:7474-7478
    • (1995) J Biol Chem , vol.270 , pp. 7474-7478
    • Buggy, J.J.1    Livingston, J.N.2    Rabin, D.U.3    Yoo-Warren, H.4
  • 11
    • 0030913105 scopus 로고    scopus 로고
    • Location of the domains involved in ligand binding and activation of the glucose-dependent insulinotropic polypeptide receptor
    • Gelling RW, Wheeler MB, Xue J, Gymorey S, Nian C, Pederson RA, McIntosh CH 1997 Location of the domains involved in ligand binding and activation of the glucose-dependent insulinotropic polypeptide receptor. Endocrinology 138:2640-2643
    • (1997) Endocrinology , vol.138 , pp. 2640-2643
    • Gelling, R.W.1    Wheeler, M.B.2    Xue, J.3    Gymorey, S.4    Nian, C.5    Pederson, R.A.6    McIntosh, C.H.7
  • 12
    • 0030012358 scopus 로고    scopus 로고
    • Glucagon and GLP-1: Lessons from chimeric receptors and chimeric peptides
    • Hjorth SA, Schwartz TW 1996 Glucagon and GLP-1: lessons from chimeric receptors and chimeric peptides. Acta Physiol Scand 157:343-345
    • (1996) Acta Physiol Scand , vol.157 , pp. 343-345
    • Hjorth, S.A.1    Schwartz, T.W.2
  • 13
    • 0029043789 scopus 로고
    • Critical contributions of amino-terminal extracellular domains in agonist binding and activation of secretin and vasoactive intestinal polypeptide receptors
    • Holtmann MH, Hadac EM, Miller LJ 1995 Critical contributions of amino-terminal extracellular domains in agonist binding and activation of secretin and vasoactive intestinal polypeptide receptors. J Biol Chem 270:14394-14398
    • (1995) J Biol Chem , vol.270 , pp. 14394-14398
    • Holtmann, M.H.1    Hadac, E.M.2    Miller, L.J.3
  • 15
    • 0028998560 scopus 로고
    • Mutational analysis of cysteine residues within the extracellular domains of the human vasoactive intestinal peptide (VIP) 1 receptor identifies seven mutants that are defective in VIP binding
    • Gaudin P, Couvineau A, Maoret J-J, Royer-Fessard C, Laburthe M 1995 Mutational analysis of cysteine residues within the extracellular domains of the human vasoactive intestinal peptide (VIP) 1 receptor identifies seven mutants that are defective in VIP binding. Biochem Biophys Res Commun 211:901-908
    • (1995) Biochem Biophys Res Commun , vol.211 , pp. 901-908
    • Gaudin, P.1    Couvineau, A.2    Maoret, J.-J.3    Royer-Fessard, C.4    Laburthe, M.5
  • 16
    • 0028230817 scopus 로고
    • Expanding horizons for receptors coupled to G proteins: Diversity and disease
    • Coughlin SR 1994 Expanding horizons for receptors coupled to G proteins: diversity and disease. Curr Topics Cell Biol 6:191-197
    • (1994) Curr Topics Cell Biol , vol.6 , pp. 191-197
    • Coughlin, S.R.1
  • 18
    • 0027959963 scopus 로고
    • High agonist-independent activity is a distinguishing feature of the dopamine D1B receptor subtype
    • Tiberi M, Caron M 1994 High agonist-independent activity is a distinguishing feature of the dopamine D1B receptor subtype. J Biol Chem 269:27925-27931
    • (1994) J Biol Chem , vol.269 , pp. 27925-27931
    • Tiberi, M.1    Caron, M.2
  • 19
    • 0027513982 scopus 로고
    • A Mutation-induced activated state of the β2-adrenergic receptor
    • Samana P, Cotecchia S, Costa T, Lefkowitz RJ 1993 A Mutation-induced activated state of the β2-adrenergic receptor. J Biol Chem 268:4625-4636
    • (1993) J Biol Chem , vol.268 , pp. 4625-4636
    • Samana, P.1    Cotecchia, S.2    Costa, T.3    Lefkowitz, R.J.4
  • 23
    • 0028943780 scopus 로고
    • A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia
    • Schipani E, Kruse K, Jüppner H 1995 A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia. Science 268:98-100
    • (1995) Science , vol.268 , pp. 98-100
    • Schipani, E.1    Kruse, K.2    Jüppner, H.3
  • 24
    • 0029849784 scopus 로고    scopus 로고
    • Constitutively activated receptors for parathyroid hormone and parathyroid hormone-related peptide in Jansen-type metaphyseal chondrodysplasia
    • Schipani E, Langman CB, Parfitt AM, Jensen GS, Kikuchi S, Kooh SW, Cole WG, Jüppner H 1996 Constitutively activated receptors for parathyroid hormone and parathyroid hormone-related peptide in Jansen-type metaphyseal chondrodysplasia. N Engl J Med 335:708-714
    • (1996) N Engl J Med , vol.335 , pp. 708-714
    • Schipani, E.1    Langman, C.B.2    Parfitt, A.M.3    Jensen, G.S.4    Kikuchi, S.5    Kooh, S.W.6    Cole, W.G.7    Jüppner, H.8
  • 25
    • 0023201169 scopus 로고
    • Stimulation and inhibition of cAMP accumulation by glucagon in canine hepatocytes
    • Grady T, Fickova M, Tager HS, Trivedi D, Hruby VJ 1987 Stimulation and inhibition of cAMP accumulation by glucagon in canine hepatocytes. J Biol Chem 262: 15514-15520
    • (1987) J Biol Chem , vol.262 , pp. 15514-15520
    • Grady, T.1    Fickova, M.2    Tager, H.S.3    Trivedi, D.4    Hruby, V.J.5
  • 26
    • 0025810274 scopus 로고
    • Position 9 replacement analogs of glucagon uncouple biological activity and receptor binding
    • Unson CG, Macdonald D, Ray K, Durrah TL, Merrifield RB 1991 Position 9 replacement analogs of glucagon uncouple biological activity and receptor binding. J Biol Chem 266:2763-2766
    • (1991) J Biol Chem , vol.266 , pp. 2763-2766
    • Unson, C.G.1    Macdonald, D.2    Ray, K.3    Durrah, T.L.4    Merrifield, R.B.5
  • 27
    • 0030991648 scopus 로고    scopus 로고
    • Constitutive activation of the cyclic adenosine 3′,5′-monophosphate signalling pathway by parathyroid hormone (PTH)/PTH-related peptide receptors mutated at the two loci for Jansen's metaphyseal chondrodysplasia
    • Schipani E, Jensen GS, Pincus J, Nissenson RA, Gardella TJ, Jüppner H 1997 Constitutive activation of the cyclic adenosine 3′,5′-monophosphate signalling pathway by parathyroid hormone (PTH)/PTH-related peptide receptors mutated at the two loci for Jansen's metaphyseal chondrodysplasia. Mol Endocrinol 11:851-858
    • (1997) Mol Endocrinol , vol.11 , pp. 851-858
    • Schipani, E.1    Jensen, G.S.2    Pincus, J.3    Nissenson, R.A.4    Gardella, T.J.5    Jüppner, H.6
  • 29
    • 0028046153 scopus 로고
    • Synthesis and expression of a gene for the rat glucagon receptor
    • Carruthers CJL, Unson CG, Kim HN, Sakmar TP 1994 Synthesis and expression of a gene for the rat glucagon receptor. J Biol Chem 269:29321-29328
    • (1994) J Biol Chem , vol.269 , pp. 29321-29328
    • Carruthers, C.J.L.1    Unson, C.G.2    Kim, H.N.3    Sakmar, T.P.4
  • 30
    • 0028998560 scopus 로고
    • Mutational analysis of cysteine residue within the extracellular domains of the human vasoactive intestinal peptide (VIP) 1 receptor identifies seven mutants that are defective in VIP binding
    • Gaudin P, Couvineau A, Maoret J-J, Royer-Fessard C, Laburthe M 1995 Mutational analysis of cysteine residue within the extracellular domains of the human vasoactive intestinal peptide (VIP) 1 receptor identifies seven mutants that are defective in VIP binding. Biochem Biophys Res Commun 211:901-908
    • (1995) Biochem Biophys Res Commun , vol.211 , pp. 901-908
    • Gaudin, P.1    Couvineau, A.2    Maoret, J.-J.3    Royer-Fessard, C.4    Laburthe, M.5
  • 31
    • 0030052971 scopus 로고    scopus 로고
    • Mutations of neighboring polar residues on the second transmembrane helix disrupt signalling by the parathyroid hormone receptor
    • Turner PR, Bambino T, Nissenson RA 1996 Mutations of neighboring polar residues on the second transmembrane helix disrupt signalling by the parathyroid hormone receptor. Mol Endocrinol 10:132-139
    • (1996) Mol Endocrinol , vol.10 , pp. 132-139
    • Turner, P.R.1    Bambino, T.2    Nissenson, R.A.3
  • 33
    • 15644378264 scopus 로고    scopus 로고
    • Characterization of a constitutively active mutant of the human vasocactive intestinal peptide (VIP) 1 receptor
    • Abstract
    • Gaudin P, Royer-Fessard C, Couvineau A, Maoret J-J, Laburthe M 1996 Characterization of a constitutively active mutant of the human vasocactive intestinal peptide (VIP) 1 receptor. Regul Pept 64:49 (Abstract)
    • (1996) Regul Pept , vol.64 , pp. 49
    • Gaudin, P.1    Royer-Fessard, C.2    Couvineau, A.3    Maoret, J.-J.4    Laburthe, M.5
  • 34
    • 0030601059 scopus 로고    scopus 로고
    • Point mutations in the first and third intracellular loops of the glucagon-like peptide-1 receptor alter intracellular signalling
    • Heller RS, Kieffer TJ, Habener JF 1996 Point mutations in the first and third intracellular loops of the glucagon-like peptide-1 receptor alter intracellular signalling. Biochem Biophys Res Commun 223:624-632
    • (1996) Biochem Biophys Res Commun , vol.223 , pp. 624-632
    • Heller, R.S.1    Kieffer, T.J.2    Habener, J.F.3
  • 35
    • 0031555863 scopus 로고    scopus 로고
    • A point mutation in the glucose-dependent insulinotropic peptide receptor confers constitutive activity
    • Tseng CC, Lin L 1997 A point mutation in the glucose-dependent insulinotropic peptide receptor confers constitutive activity. Biochem Biophys Res Commun 232:96-100
    • (1997) Biochem Biophys Res Commun , vol.232 , pp. 96-100
    • Tseng, C.C.1    Lin, L.2
  • 36
    • 0029832901 scopus 로고    scopus 로고
    • Transmembrane regions V and VI of the human luteinizing hormone receptor are required for constitutive activation by a mutation in the third intracellular loop
    • Kudo M, Osuga Y, Kobilka BK, Hsueh AJW 1996 Transmembrane regions V and VI of the human luteinizing hormone receptor are required for constitutive activation by a mutation in the third intracellular loop. J Biol Chem 37:22470-22478
    • (1996) J Biol Chem , vol.37 , pp. 22470-22478
    • Kudo, M.1    Osuga, Y.2    Kobilka, B.K.3    Hsueh, A.J.W.4
  • 37
    • 0029816971 scopus 로고    scopus 로고
    • Inverse agonism of amino-terminally truncated parathyroid hormone (PTH) and PTH-related peptide (PTHrP) analogs revealed with constitutively active mutant PTH/PTHrP receptors
    • Gardella TJ, Luck MD, Jensen GS, Schipani E, Potts Jr JT, Jüppner H 1996 Inverse agonism of amino-terminally truncated parathyroid hormone (PTH) and PTH-related peptide (PTHrP) analogs revealed with constitutively active mutant PTH/PTHrP receptors. Endocrinology 137:3936-3941
    • (1996) Endocrinology , vol.137 , pp. 3936-3941
    • Gardella, T.J.1    Luck, M.D.2    Jensen, G.S.3    Schipani, E.4    Potts Jr., J.T.5    Jüppner, H.6
  • 38
    • 0024556150 scopus 로고
    • Engineering hybrid genes without the use of restriction enzymes: Gene splicing by overlap extension
    • Horton RM, Hunt HD, Ho SN, Pullen JK, Pease LR 1989 Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension. Gene 77:51-59
    • (1989) Gene , vol.77 , pp. 51-59
    • Horton, R.M.1    Hunt, H.D.2    Ho, S.N.3    Pullen, J.K.4    Pease, L.R.5
  • 39
    • 0025358427 scopus 로고
    • Biosynthesis of peptide precursors and protease inhibitors using new constitutive and inducible eukaryotic expression vectors
    • Johansen TE, Schøller MS, Tolstoy S, Schwartz TW 1990 Biosynthesis of peptide precursors and protease inhibitors using new constitutive and inducible eukaryotic expression vectors. FEBS Lett 267:289-294
    • (1990) FEBS Lett , vol.267 , pp. 289-294
    • Johansen, T.E.1    Schøller, M.S.2    Tolstoy, S.3    Schwartz, T.W.4
  • 41
    • 0016374975 scopus 로고
    • A highly sensitive adenylate cyclase assay
    • Solomon Y, Londos C, Rodbell M 1974 A highly sensitive adenylate cyclase assay. Anal Biochem 58:541
    • (1974) Anal Biochem , vol.58 , pp. 541
    • Solomon, Y.1    Londos, C.2    Rodbell, M.3


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