-
1
-
-
84856226112
-
Immunomodulatory functions of type I interferons
-
Gonzalez-Navajas, J.M., et al. Immunomodulatory functions of type I interferons. Nat. Rev. Immunol. 12 (2012), 125–135.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 125-135
-
-
Gonzalez-Navajas, J.M.1
-
2
-
-
84883146392
-
Structural basis of a unique interferon-beta signaling axis mediated via the receptor IFNAR1
-
de Weerd, N.A., et al. Structural basis of a unique interferon-beta signaling axis mediated via the receptor IFNAR1. Nat. Immunol. 14 (2013), 901–907.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 901-907
-
-
de Weerd, N.A.1
-
3
-
-
84879318140
-
Immune activation and HIV persistence: implications for curative approaches to HIV infection
-
Klatt, N.R., et al. Immune activation and HIV persistence: implications for curative approaches to HIV infection. Immunol. Rev. 254 (2013), 326–342.
-
(2013)
Immunol. Rev.
, vol.254
, pp. 326-342
-
-
Klatt, N.R.1
-
4
-
-
72849132344
-
Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys
-
Bosinger, S.E., et al. Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys. J. Clin. Invest. 119 (2009), 3556–3572.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3556-3572
-
-
Bosinger, S.E.1
-
5
-
-
77954498359
-
Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques
-
Harris, L.D., et al. Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques. J. Virol. 84 (2010), 7886–7891.
-
(2010)
J. Virol.
, vol.84
, pp. 7886-7891
-
-
Harris, L.D.1
-
6
-
-
72849136282
-
Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response
-
Jacquelin, B., et al. Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response. J. Clin. Invest. 119 (2009), 3544–3555.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3544-3555
-
-
Jacquelin, B.1
-
7
-
-
84956771914
-
Type I and Type II interferon coordinately regulate suppressive dendritic cell fate and function during viral persistence
-
Cunningham, C.R., et al. Type I and Type II interferon coordinately regulate suppressive dendritic cell fate and function during viral persistence. PLoS Pathog., 12, 2016, e1005356.
-
(2016)
PLoS Pathog.
, vol.12
, pp. e1005356
-
-
Cunningham, C.R.1
-
8
-
-
34848852256
-
Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection
-
Mueller, S.N., et al. Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection. Proc. Natl. Acad. Sci. U. S. A. 104 (2007), 15430–15435.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 15430-15435
-
-
Mueller, S.N.1
-
9
-
-
84959292227
-
IDO in the tumor microenvironment: inflammation, counter-regulation, and tolerance
-
Munn, D.H., Mellor, A.L., IDO in the tumor microenvironment: inflammation, counter-regulation, and tolerance. Trends Immunol. 37 (2016), 193–207.
-
(2016)
Trends Immunol.
, vol.37
, pp. 193-207
-
-
Munn, D.H.1
Mellor, A.L.2
-
10
-
-
84883863501
-
Up-regulation of PD–L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells
-
Spranger, S., et al. Up-regulation of PD–L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells. Sci. Transl. Med., 5, 2013, 200ra116.
-
(2013)
Sci. Transl. Med.
, vol.5
, pp. 200ra116
-
-
Spranger, S.1
-
11
-
-
84876311772
-
Persistent LCMV infection is controlled by blockade of type I interferon signaling
-
Teijaro, J.R., et al. Persistent LCMV infection is controlled by blockade of type I interferon signaling. Science 340 (2013), 207–211.
-
(2013)
Science
, vol.340
, pp. 207-211
-
-
Teijaro, J.R.1
-
12
-
-
84876299371
-
Blockade of chronic type I interferon signaling to control persistent LCMV infection
-
Wilson, E.B., et al. Blockade of chronic type I interferon signaling to control persistent LCMV infection. Science 340 (2013), 202–207.
-
(2013)
Science
, vol.340
, pp. 202-207
-
-
Wilson, E.B.1
-
13
-
-
85001996779
-
Tumor interferon signaling regulates a multigenic resistance program to immune checkpoint blockade
-
1540–1554 e1512
-
Benci, J.L., et al. Tumor interferon signaling regulates a multigenic resistance program to immune checkpoint blockade. Cell, 167, 2016 1540–1554 e1512.
-
(2016)
Cell
, vol.167
-
-
Benci, J.L.1
-
14
-
-
0025222683
-
Regulation of indoleamine 2, 3-dioxygenase gene expression in human fibroblasts by interferon-gamma. Upstream control region discriminates between interferon-gamma and interferon-alpha
-
Dai, W., Gupta, S.L., Regulation of indoleamine 2, 3-dioxygenase gene expression in human fibroblasts by interferon-gamma. Upstream control region discriminates between interferon-gamma and interferon-alpha. J. Biol. Chem. 265 (1990), 19871–19877.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 19871-19877
-
-
Dai, W.1
Gupta, S.L.2
-
15
-
-
85016122182
-
Bortezomib relieves immune tolerance in nasopharyngeal carcinoma via STAT1 suppression and indoleamine 2,3-dioxygenase downregulation
-
Jiang, G.M., et al. Bortezomib relieves immune tolerance in nasopharyngeal carcinoma via STAT1 suppression and indoleamine 2,3-dioxygenase downregulation. Cancer Immunol. Res. 5 (2017), 42–51.
-
(2017)
Cancer Immunol. Res.
, vol.5
, pp. 42-51
-
-
Jiang, G.M.1
-
16
-
-
84865296997
-
Amino acid catabolism: a pivotal regulator of innate and adaptive immunity
-
McGaha, T.L., et al. Amino acid catabolism: a pivotal regulator of innate and adaptive immunity. Immunol. Rev. 249 (2012), 135–157.
-
(2012)
Immunol. Rev.
, vol.249
, pp. 135-157
-
-
McGaha, T.L.1
-
17
-
-
79952767536
-
IFN-alpha directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity
-
Terawaki, S., et al. IFN-alpha directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity. J. Immunol. 186 (2011), 2772–2779.
-
(2011)
J. Immunol.
, vol.186
, pp. 2772-2779
-
-
Terawaki, S.1
-
18
-
-
84886698315
-
Innate and adaptive immune cells in the tumor microenvironment
-
Gajewski, T.F., et al. Innate and adaptive immune cells in the tumor microenvironment. Nat. Immunol. 14 (2013), 1014–1022.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 1014-1022
-
-
Gajewski, T.F.1
-
19
-
-
84955622838
-
Alpha and beta type 1 interferon signaling: passage for diverse biologic outcomes
-
Ng, C.T., et al. Alpha and beta type 1 interferon signaling: passage for diverse biologic outcomes. Cell 164 (2016), 349–352.
-
(2016)
Cell
, vol.164
, pp. 349-352
-
-
Ng, C.T.1
-
20
-
-
84888776867
-
Relative resistance of HIV-1 founder viruses to control by interferon-alpha
-
Fenton-May, A.E., et al. Relative resistance of HIV-1 founder viruses to control by interferon-alpha. Retrovirology, 10, 2013, 146.
-
(2013)
Retrovirology
, vol.10
, pp. 146
-
-
Fenton-May, A.E.1
-
21
-
-
84992358101
-
Resistance of transmitted founder HIV-1 to IFITM-mediated restriction
-
Foster, T.L., et al. Resistance of transmitted founder HIV-1 to IFITM-mediated restriction. Cell Host Microbe 20 (2016), 429–442.
-
(2016)
Cell Host Microbe
, vol.20
, pp. 429-442
-
-
Foster, T.L.1
-
22
-
-
84876867850
-
Phenotypic properties of transmitted founder HIV-1
-
Parrish, N.F., et al. Phenotypic properties of transmitted founder HIV-1. Proc. Natl. Acad. Sci. U. S. A. 110 (2013), 6626–6633.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 6626-6633
-
-
Parrish, N.F.1
-
23
-
-
84942133739
-
Fitness-balanced escape determines resolution of dynamic founder virus escape processes in HIV-1 infection
-
Sunshine, J.E., et al. Fitness-balanced escape determines resolution of dynamic founder virus escape processes in HIV-1 infection. J. Virol. 89 (2015), 10303–10318.
-
(2015)
J. Virol.
, vol.89
, pp. 10303-10318
-
-
Sunshine, J.E.1
-
24
-
-
85003040921
-
Transmission of multiple HIV-1 subtype C transmitted/founder viruses into the same recipients was not determined by modest phenotypic differences
-
Song, H., et al. Transmission of multiple HIV-1 subtype C transmitted/founder viruses into the same recipients was not determined by modest phenotypic differences. Sci. Rep., 6, 2016, 38130.
-
(2016)
Sci. Rep.
, vol.6
, pp. 38130
-
-
Song, H.1
-
25
-
-
84910491603
-
A multiple-dose phase I trial of recombinant leukocyte A interferon in cancer patients
-
Sherwin, S.A., et al. A multiple-dose phase I trial of recombinant leukocyte A interferon in cancer patients. JAMA 248 (1982), 2461–2466.
-
(1982)
JAMA
, vol.248
, pp. 2461-2466
-
-
Sherwin, S.A.1
-
26
-
-
0028875086
-
Evidence for different modes of action of cyclin-dependent kinase inhibitors: p15 and p16 bind to kinases, p21 and p27 bind to cyclins
-
Hall, M., et al. Evidence for different modes of action of cyclin-dependent kinase inhibitors: p15 and p16 bind to kinases, p21 and p27 bind to cyclins. Oncogene 11 (1995), 1581–1588.
-
(1995)
Oncogene
, vol.11
, pp. 1581-1588
-
-
Hall, M.1
-
27
-
-
0033529122
-
Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins
-
Sangfelt, O., et al. Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins. Oncogene 18 (1999), 2798–2810.
-
(1999)
Oncogene
, vol.18
, pp. 2798-2810
-
-
Sangfelt, O.1
-
28
-
-
84878958382
-
Synergy between RA and TLR3 promotes type I IFN-dependent apoptosis through upregulation of TRAIL pathway in breast cancer cells
-
Bernardo, A.R., et al. Synergy between RA and TLR3 promotes type I IFN-dependent apoptosis through upregulation of TRAIL pathway in breast cancer cells. Cell Death Dis., 4, 2013, e479.
-
(2013)
Cell Death Dis.
, vol.4
, pp. e479
-
-
Bernardo, A.R.1
-
29
-
-
0034895641
-
Preferential induction of apoptosis by interferon (IFN)-beta compared with IFN-alpha2: correlation with TRAIL/Apo2L induction in melanoma cell lines
-
Chawla-Sarkar, M., et al. Preferential induction of apoptosis by interferon (IFN)-beta compared with IFN-alpha2: correlation with TRAIL/Apo2L induction in melanoma cell lines. Clin. Cancer Res. 7 (2001), 1821–1831.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1821-1831
-
-
Chawla-Sarkar, M.1
-
30
-
-
84873871853
-
Type I interferons induce apoptosis by balancing cFLIP and caspase-8 independent of death ligands
-
Apelbaum, A., et al. Type I interferons induce apoptosis by balancing cFLIP and caspase-8 independent of death ligands. Mol. Cell Biol. 33 (2013), 800–814.
-
(2013)
Mol. Cell Biol.
, vol.33
, pp. 800-814
-
-
Apelbaum, A.1
-
31
-
-
84864654660
-
Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape
-
Bidwell, B.N., et al. Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape. Nat. Med. 18 (2012), 1224–1231.
-
(2012)
Nat. Med.
, vol.18
, pp. 1224-1231
-
-
Bidwell, B.N.1
-
32
-
-
0036793979
-
Prognostic significance of signal transducer and activator of transcription 1 activation in breast cancer
-
Widschwendter, A., et al. Prognostic significance of signal transducer and activator of transcription 1 activation in breast cancer. Clin. Cancer Res. 8 (2002), 3065–3074.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3065-3074
-
-
Widschwendter, A.1
-
33
-
-
84901933676
-
Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression
-
Sandler, N.G., et al. Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression. Nature 511 (2014), 601–605.
-
(2014)
Nature
, vol.511
, pp. 601-605
-
-
Sandler, N.G.1
-
34
-
-
84883818901
-
SIV infection of rhesus macaques differentially impacts mononuclear phagocyte responses to virus-derived TLR agonists
-
Wonderlich, E.R., Barratt-Boyes, S.M., SIV infection of rhesus macaques differentially impacts mononuclear phagocyte responses to virus-derived TLR agonists. J. Med. Primatol. 42 (2013), 247–253.
-
(2013)
J. Med. Primatol.
, vol.42
, pp. 247-253
-
-
Wonderlich, E.R.1
Barratt-Boyes, S.M.2
-
35
-
-
53349143044
-
Persistent virus infection inhibits type I interferon production by plasmacytoid dendritic cells to facilitate opportunistic infections
-
Zuniga, E.I., et al. Persistent virus infection inhibits type I interferon production by plasmacytoid dendritic cells to facilitate opportunistic infections. Cell Host Microbe 4 (2008), 374–386.
-
(2008)
Cell Host Microbe
, vol.4
, pp. 374-386
-
-
Zuniga, E.I.1
-
36
-
-
84884741768
-
Negative regulation of type I IFN expression by OASL1 permits chronic viral infection and CD8(+) T-cell exhaustion
-
Lee, M.S., et al. Negative regulation of type I IFN expression by OASL1 permits chronic viral infection and CD8(+) T-cell exhaustion. PLoS Pathog., 9, 2013, e1003478.
-
(2013)
PLoS Pathog.
, vol.9
, pp. e1003478
-
-
Lee, M.S.1
-
37
-
-
84862294199
-
Timing and magnitude of type I interferon responses by distinct sensors impact CD8 T cell exhaustion and chronic viral infection
-
Wang, Y., et al. Timing and magnitude of type I interferon responses by distinct sensors impact CD8 T cell exhaustion and chronic viral infection. Cell Host Microbe 11 (2012), 631–642.
-
(2012)
Cell Host Microbe
, vol.11
, pp. 631-642
-
-
Wang, Y.1
-
38
-
-
84956883293
-
Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN-I responses
-
Honke, N., et al. Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN-I responses. Eur. J. Immunol. 46 (2016), 372–380.
-
(2016)
Eur. J. Immunol.
, vol.46
, pp. 372-380
-
-
Honke, N.1
-
39
-
-
84978864753
-
Type I interferon receptor deficiency in dendritic cells facilitates systemic murine norovirus persistence despite enhanced adaptive immunity
-
Nice, T.J., et al. Type I interferon receptor deficiency in dendritic cells facilitates systemic murine norovirus persistence despite enhanced adaptive immunity. PLoS Pathog., 12, 2016, e1005684.
-
(2016)
PLoS Pathog.
, vol.12
, pp. e1005684
-
-
Nice, T.J.1
-
40
-
-
84861144540
-
Emergence of distinct multiarmed immunoregulatory antigen-presenting cells during persistent viral infection
-
Wilson, E.B., et al. Emergence of distinct multiarmed immunoregulatory antigen-presenting cells during persistent viral infection. Cell Host Microbe 11 (2012), 481–491.
-
(2012)
Cell Host Microbe
, vol.11
, pp. 481-491
-
-
Wilson, E.B.1
-
41
-
-
84884344619
-
Monocyte-derived dendritic cells perform hemophagocytosis to fine-tune excessive immune responses
-
Ohyagi, H., et al. Monocyte-derived dendritic cells perform hemophagocytosis to fine-tune excessive immune responses. Immunity 39 (2013), 584–598.
-
(2013)
Immunity
, vol.39
, pp. 584-598
-
-
Ohyagi, H.1
-
42
-
-
80355147292
-
Type I interferon is selectively required by dendritic cells for immune rejection of tumors
-
Diamond, M.S., et al. Type I interferon is selectively required by dendritic cells for immune rejection of tumors. J. Exp. Med. 208 (2011), 1989–2003.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1989-2003
-
-
Diamond, M.S.1
-
43
-
-
80355136945
-
Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells
-
Fuertes, M.B., et al. Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells. J. Exp. Med. 208 (2011), 2005–2016.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 2005-2016
-
-
Fuertes, M.B.1
-
44
-
-
9444265268
-
Dendritic cell infiltration and prognosis of early stage breast cancer
-
Treilleux, I., et al. Dendritic cell infiltration and prognosis of early stage breast cancer. Clin. Cancer Res. 10 (2004), 7466–7474.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 7466-7474
-
-
Treilleux, I.1
-
45
-
-
0038545821
-
Recruitment of immature plasmacytoid dendritic cells (plasmacytoid monocytes) and myeloid dendritic cells in primary cutaneous melanomas
-
Vermi, W., et al. Recruitment of immature plasmacytoid dendritic cells (plasmacytoid monocytes) and myeloid dendritic cells in primary cutaneous melanomas. J. Pathol. 200 (2003), 255–268.
-
(2003)
J. Pathol.
, vol.200
, pp. 255-268
-
-
Vermi, W.1
-
46
-
-
84867520423
-
Impaired IFN-alpha production by plasmacytoid dendritic cells favors regulatory T-cell expansion that may contribute to breast cancer progression
-
Sisirak, V., et al. Impaired IFN-alpha production by plasmacytoid dendritic cells favors regulatory T-cell expansion that may contribute to breast cancer progression. Cancer Res. 72 (2012), 5188–5197.
-
(2012)
Cancer Res.
, vol.72
, pp. 5188-5197
-
-
Sisirak, V.1
-
47
-
-
4043092238
-
Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes
-
Munn, D.H., et al. Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. J. Clin. Invest. 114 (2004), 280–290.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 280-290
-
-
Munn, D.H.1
-
48
-
-
68849129604
-
Simultaneous Foxp3 and IDO expression is associated with sentinel lymph node metastases in breast cancer
-
Mansfield, A.S., et al. Simultaneous Foxp3 and IDO expression is associated with sentinel lymph node metastases in breast cancer. BMC Cancer, 9, 2009, 231.
-
(2009)
BMC Cancer
, vol.9
, pp. 231
-
-
Mansfield, A.S.1
-
49
-
-
84865118647
-
Indoleamine 2,3-dioxygenase, a new prognostic marker in sentinel lymph nodes of melanoma patients
-
Speeckaert, R., et al. Indoleamine 2,3-dioxygenase, a new prognostic marker in sentinel lymph nodes of melanoma patients. Eur. J. Cancer 48 (2012), 2004–2011.
-
(2012)
Eur. J. Cancer
, vol.48
, pp. 2004-2011
-
-
Speeckaert, R.1
-
50
-
-
84964334050
-
Constitutive aryl hydrocarbon receptor signaling constrains type I interferon-mediated antiviral innate defense
-
Yamada, T., et al. Constitutive aryl hydrocarbon receptor signaling constrains type I interferon-mediated antiviral innate defense. Nat. Immunol. 17 (2016), 687–694.
-
(2016)
Nat. Immunol.
, vol.17
, pp. 687-694
-
-
Yamada, T.1
-
51
-
-
85002247420
-
The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment
-
Sharma, M.D., et al. The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment. Sci. Adv., 1, 2015, e1500845.
-
(2015)
Sci. Adv.
, vol.1
, pp. e1500845
-
-
Sharma, M.D.1
-
52
-
-
80052670800
-
Tolerance induced by apoptotic antigen-coupled leukocytes is induced by PD-L1+ and IL-10-producing splenic macrophages and maintained by T regulatory cells
-
Getts, D.R., et al. Tolerance induced by apoptotic antigen-coupled leukocytes is induced by PD-L1+ and IL-10-producing splenic macrophages and maintained by T regulatory cells. J. Immunol. 187 (2011), 2405–2417.
-
(2011)
J. Immunol.
, vol.187
, pp. 2405-2417
-
-
Getts, D.R.1
-
53
-
-
84863231381
-
Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase
-
Ravishankar, B., et al. Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 3909–3914.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 3909-3914
-
-
Ravishankar, B.1
-
54
-
-
84885169498
-
Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells induces potent tolerogenic responses
-
Huang, L., et al. Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells induces potent tolerogenic responses. J. Immunol. 191 (2013), 3509–3513.
-
(2013)
J. Immunol.
, vol.191
, pp. 3509-3513
-
-
Huang, L.1
-
55
-
-
84912128872
-
STING-dependent cytosolic DNA sensing promotes radiation-induced type I interferon-dependent antitumor immunity in immunogenic tumors
-
Deng, L., et al. STING-dependent cytosolic DNA sensing promotes radiation-induced type I interferon-dependent antitumor immunity in immunogenic tumors. Immunity 41 (2014), 843–852.
-
(2014)
Immunity
, vol.41
, pp. 843-852
-
-
Deng, L.1
-
56
-
-
84912120595
-
STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors
-
Woo, S.R., et al. STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors. Immunity 41 (2014), 830–842.
-
(2014)
Immunity
, vol.41
, pp. 830-842
-
-
Woo, S.R.1
-
57
-
-
84929705879
-
Direct activation of STING in the tumor microenvironment leads to potent and systemic tumor regression and immunity
-
Corrales, L., et al. Direct activation of STING in the tumor microenvironment leads to potent and systemic tumor regression and immunity. Cell Rep. 11 (2015), 1018–1030.
-
(2015)
Cell Rep.
, vol.11
, pp. 1018-1030
-
-
Corrales, L.1
-
58
-
-
85018382461
-
A STING-activating nanovaccine for cancer immunotherapy
-
Published online April 24, 2017.
-
Luo, M., et al. A STING-activating nanovaccine for cancer immunotherapy. Nat. Nanotechnol., 2017, 10.1038/nnano.2017.52 Published online April 24, 2017.
-
(2017)
Nat. Nanotechnol.
-
-
Luo, M.1
-
59
-
-
85020211893
-
Biopolymers codelivering engineered T cells and STING agonists can eliminate heterogeneous tumors
-
Published online April 24, 2017.
-
Smith, T.T., et al. Biopolymers codelivering engineered T cells and STING agonists can eliminate heterogeneous tumors. J. Clin. Invest., 2017, 10.1172/JCI87624 Published online April 24, 2017.
-
(2017)
J. Clin. Invest.
-
-
Smith, T.T.1
-
60
-
-
84902654063
-
Type I interferons protect T cells against NK cell attack mediated by the activating receptor NCR1
-
Crouse, J., et al. Type I interferons protect T cells against NK cell attack mediated by the activating receptor NCR1. Immunity 40 (2014), 961–973.
-
(2014)
Immunity
, vol.40
, pp. 961-973
-
-
Crouse, J.1
-
61
-
-
24344478196
-
Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
-
Kolumam, G.A., et al. Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection. J. Exp. Med. 202 (2005), 637–650.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 637-650
-
-
Kolumam, G.A.1
-
62
-
-
84856062668
-
Type-I IFN drives the differentiation of short-lived effector CD8+ T cells in vivo
-
Wiesel, M., et al. Type-I IFN drives the differentiation of short-lived effector CD8+ T cells in vivo. Eur. J. Immunol. 42 (2012), 320–329.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 320-329
-
-
Wiesel, M.1
-
63
-
-
84902651736
-
Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity
-
Xu, H.C., et al. Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity. Immunity 40 (2014), 949–960.
-
(2014)
Immunity
, vol.40
, pp. 949-960
-
-
Xu, H.C.1
-
64
-
-
33746010366
-
Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation
-
Thompson, L.J., et al. Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation. J. Immunol. 177 (2006), 1746–1754.
-
(2006)
J. Immunol.
, vol.177
, pp. 1746-1754
-
-
Thompson, L.J.1
-
65
-
-
84997122944
-
Type I interferon suppresses virus-specific B cell responses by modulating CD8+ T cell differentiation
-
Moseman, E.A., et al. Type I interferon suppresses virus-specific B cell responses by modulating CD8+ T cell differentiation. Sci. Immunol., 1, 2016, eaah3565.
-
(2016)
Sci. Immunol.
, vol.1
, pp. eaah3565
-
-
Moseman, E.A.1
-
66
-
-
78649591558
-
Effects of IFN-alpha as a signal-3 cytokine on human naive and antigen-experienced CD8(+) T cells
-
Hervas-Stubbs, S., et al. Effects of IFN-alpha as a signal-3 cytokine on human naive and antigen-experienced CD8(+) T cells. Eur. J. Immunol. 40 (2010), 3389–3402.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 3389-3402
-
-
Hervas-Stubbs, S.1
-
67
-
-
85012931658
-
Inactivation of interferon receptor promotes the establishment of immune privileged tumor microenvironment
-
Katlinski, K.V., et al. Inactivation of interferon receptor promotes the establishment of immune privileged tumor microenvironment. Cancer Cell 31 (2017), 194–207.
-
(2017)
Cancer Cell
, vol.31
, pp. 194-207
-
-
Katlinski, K.V.1
-
68
-
-
85014738071
-
The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness
-
Wu, T., et al. The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness. Sci. Immunol., 1, 2016, eaai8593.
-
(2016)
Sci. Immunol.
, vol.1
, pp. eaai8593
-
-
Wu, T.1
-
69
-
-
84988410229
-
Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection
-
He, R., et al. Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection. Nature 537 (2016), 412–428.
-
(2016)
Nature
, vol.537
, pp. 412-428
-
-
He, R.1
-
70
-
-
84988266244
-
Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
-
Im, S.J., et al. Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy. Nature 537 (2016), 417–421.
-
(2016)
Nature
, vol.537
, pp. 417-421
-
-
Im, S.J.1
-
71
-
-
85002609650
-
T cell factor 1-expressing memory-like CD8(+) T cells sustain the immune response to chronic viral infections
-
Utzschneider, D.T., et al. T cell factor 1-expressing memory-like CD8(+) T cells sustain the immune response to chronic viral infections. Immunity 45 (2016), 415–427.
-
(2016)
Immunity
, vol.45
, pp. 415-427
-
-
Utzschneider, D.T.1
-
72
-
-
84901008927
-
Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection
-
Osokine, I., et al. Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection. Proc. Natl. Acad. Sci. U. S. A. 111 (2014), 7409–7414.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 7409-7414
-
-
Osokine, I.1
-
73
-
-
84896372779
-
Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells
-
Ray, J.P., et al. Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells. Immunity 40 (2014), 367–377.
-
(2014)
Immunity
, vol.40
, pp. 367-377
-
-
Ray, J.P.1
-
74
-
-
84990070032
-
Overcoming CD4 Th1 cell fate restrictions to sustain antiviral CD8 T cells and control persistent virus infection
-
Snell, L.M., et al. Overcoming CD4 Th1 cell fate restrictions to sustain antiviral CD8 T cells and control persistent virus infection. Cell Rep. 16 (2016), 3286–3296.
-
(2016)
Cell Rep.
, vol.16
, pp. 3286-3296
-
-
Snell, L.M.1
-
75
-
-
84867550856
-
Patients with chronic hepatitis C express a high percentage of CD4(+)CXCR5(+) T follicular helper cells
-
Feng, J., et al. Patients with chronic hepatitis C express a high percentage of CD4(+)CXCR5(+) T follicular helper cells. J. Gastroenterol. 47 (2012), 1048–1056.
-
(2012)
J. Gastroenterol.
, vol.47
, pp. 1048-1056
-
-
Feng, J.1
-
76
-
-
84865997747
-
Expansion of HIV-specific T follicular helper cells in chronic HIV infection
-
Lindqvist, M., et al. Expansion of HIV-specific T follicular helper cells in chronic HIV infection. J. Clin. Invest. 122 (2012), 3271–3280.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 3271-3280
-
-
Lindqvist, M.1
-
77
-
-
84865395104
-
CD4 T follicular helper cell dynamics during SIV infection
-
Petrovas, C., et al. CD4 T follicular helper cell dynamics during SIV infection. J. Clin. Invest. 122 (2012), 3281–3294.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 3281-3294
-
-
Petrovas, C.1
-
78
-
-
84900418447
-
Enlarged memory T-cell pool and enhanced Th1-type responses in chronic myeloid leukemia patients who have successfully discontinued IFN-alpha monotherapy
-
Ilander, M., et al. Enlarged memory T-cell pool and enhanced Th1-type responses in chronic myeloid leukemia patients who have successfully discontinued IFN-alpha monotherapy. PLoS One, 9, 2014, e87794.
-
(2014)
PLoS One
, vol.9
, pp. e87794
-
-
Ilander, M.1
-
79
-
-
84866342671
-
Polyfunctional CD4(+) T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy
-
Ding, Z.C., et al. Polyfunctional CD4(+) T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy. Blood 120 (2012), 2229–2239.
-
(2012)
Blood
, vol.120
, pp. 2229-2239
-
-
Ding, Z.C.1
-
80
-
-
77950600201
-
Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype
-
Ding, Z.C., et al. Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype. Blood 115 (2010), 2397–2406.
-
(2010)
Blood
, vol.115
, pp. 2397-2406
-
-
Ding, Z.C.1
-
81
-
-
84903990337
-
Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis
-
Ding, Z.C., et al. Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis. Cancer Res. 74 (2014), 3441–3453.
-
(2014)
Cancer Res.
, vol.74
, pp. 3441-3453
-
-
Ding, Z.C.1
-
82
-
-
84899746524
-
Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection
-
Srivastava, S., et al. Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection. J. Exp. Med. 211 (2014), 961–974.
-
(2014)
J. Exp. Med.
, vol.211
, pp. 961-974
-
-
Srivastava, S.1
-
83
-
-
84921629557
-
Regulatory T cells resist virus infection-induced apoptosis
-
Che, J.W., et al. Regulatory T cells resist virus infection-induced apoptosis. J. Virol. 89 (2015), 2112–2120.
-
(2015)
J. Virol.
, vol.89
, pp. 2112-2120
-
-
Che, J.W.1
-
84
-
-
84881635553
-
Role of regulatory T cells during virus infection
-
Veiga-Parga, T., et al. Role of regulatory T cells during virus infection. Immunol. Rev. 255 (2013), 182–196.
-
(2013)
Immunol. Rev.
, vol.255
, pp. 182-196
-
-
Veiga-Parga, T.1
-
85
-
-
84906536054
-
Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection
-
Penaloza-MacMaster, P., et al. Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection. J. Exp. Med. 211 (2014), 1905–1918.
-
(2014)
J. Exp. Med.
, vol.211
, pp. 1905-1918
-
-
Penaloza-MacMaster, P.1
-
86
-
-
84977570635
-
INFalpha–2b inhibitory effects on CD4(+)CD25(+)FOXP3(+) regulatory T cells in the tumor microenvironment of C57BL/6 J mice with melanoma xenografts
-
Yu, Y., et al. INFalpha–2b inhibitory effects on CD4(+)CD25(+)FOXP3(+) regulatory T cells in the tumor microenvironment of C57BL/6 J mice with melanoma xenografts. BMC Cancer, 16, 2016, 397.
-
(2016)
BMC Cancer
, vol.16
, pp. 397
-
-
Yu, Y.1
-
87
-
-
84925933497
-
Type I IFN gene delivery suppresses regulatory T cells within tumors
-
Hashimoto, H., et al. Type I IFN gene delivery suppresses regulatory T cells within tumors. Cancer Gene Ther. 21 (2014), 532–541.
-
(2014)
Cancer Gene Ther.
, vol.21
, pp. 532-541
-
-
Hashimoto, H.1
-
88
-
-
84884798380
-
Interferon-alpha suppresses cAMP to disarm human regulatory T cells
-
Bacher, N., et al. Interferon-alpha suppresses cAMP to disarm human regulatory T cells. Cancer Res. 73 (2013), 5647–5656.
-
(2013)
Cancer Res.
, vol.73
, pp. 5647-5656
-
-
Bacher, N.1
-
89
-
-
84887462082
-
Interferon-dependent IL-10 production by Tregs limits tumor Th17 inflammation
-
Stewart, C.A., et al. Interferon-dependent IL-10 production by Tregs limits tumor Th17 inflammation. J. Clin. Invest. 123 (2013), 4859–4874.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 4859-4874
-
-
Stewart, C.A.1
-
90
-
-
78650124721
-
Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice
-
Sharma, M.D., et al. Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice. Immunity 33 (2010), 942–954.
-
(2010)
Immunity
, vol.33
, pp. 942-954
-
-
Sharma, M.D.1
-
91
-
-
34147115208
-
HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells
-
Boasso, A., et al. HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells. Blood 109 (2007), 3351–3359.
-
(2007)
Blood
, vol.109
, pp. 3351-3359
-
-
Boasso, A.1
-
92
-
-
79956104027
-
Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells
-
Fahey, L.M., et al. Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells. J. Exp. Med. 208 (2011), 987–999.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 987-999
-
-
Fahey, L.M.1
-
93
-
-
85013115160
-
B-cell abnormalities and impact on antibody response in HIV infection
-
Published online February 15, 2017.
-
Noto, A., Pantaleo, G., B-cell abnormalities and impact on antibody response in HIV infection. Curr. Opin. HIV AIDS, 2017, 10.1097/COH.0000000000000359 Published online February 15, 2017.
-
(2017)
Curr. Opin. HIV AIDS
-
-
Noto, A.1
Pantaleo, G.2
-
94
-
-
55549136745
-
Early B-cell activation after West Nile virus infection requires alpha/beta interferon but not antigen receptor signaling
-
Purtha, W.E., et al. Early B-cell activation after West Nile virus infection requires alpha/beta interferon but not antigen receptor signaling. J. Virol. 82 (2008), 10964–10974.
-
(2008)
J. Virol.
, vol.82
, pp. 10964-10974
-
-
Purtha, W.E.1
-
95
-
-
84922970995
-
Antibody effector functions mediated by Fcgamma-receptors are compromised during persistent viral infection
-
Wieland, A., et al. Antibody effector functions mediated by Fcgamma-receptors are compromised during persistent viral infection. Immunity 42 (2015), 367–378.
-
(2015)
Immunity
, vol.42
, pp. 367-378
-
-
Wieland, A.1
-
96
-
-
84923052917
-
Suppression of Fcgamma-receptor-mediated antibody effector function during persistent viral infection
-
Yamada, D.H., et al. Suppression of Fcgamma-receptor-mediated antibody effector function during persistent viral infection. Immunity 42 (2015), 379–390.
-
(2015)
Immunity
, vol.42
, pp. 379-390
-
-
Yamada, D.H.1
-
97
-
-
84997566270
-
Interferon-driven deletion of antiviral B cells at the onset of chronic infection
-
Fallet, B., et al. Interferon-driven deletion of antiviral B cells at the onset of chronic infection. Sci. Immunol., 1, 2016, eaah6817.
-
(2016)
Sci. Immunol.
, vol.1
, pp. eaah6817
-
-
Fallet, B.1
-
98
-
-
84997517753
-
Inflammatory monocytes hinder antiviral B cell responses
-
Sammicheli, S., et al. Inflammatory monocytes hinder antiviral B cell responses. Sci. Immunol., 1, 2016, eaah6789.
-
(2016)
Sci. Immunol.
, vol.1
, pp. eaah6789
-
-
Sammicheli, S.1
-
99
-
-
65949125084
-
Impaired antibody response causes persistence of prototypic T cell-contained virus
-
Bergthaler, A., et al. Impaired antibody response causes persistence of prototypic T cell-contained virus. PLoS Biol., 7, 2009, e1000080.
-
(2009)
PLoS Biol.
, vol.7
, pp. e1000080
-
-
Bergthaler, A.1
-
100
-
-
62249172189
-
Enhancing SIV-specific immunity in vivo by PD-1 blockade
-
Velu, V., et al. Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature 458 (2009), 206–210.
-
(2009)
Nature
, vol.458
, pp. 206-210
-
-
Velu, V.1
-
101
-
-
84885724091
-
Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer
-
Bindea, G., et al. Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer. Immunity 39 (2013), 782–795.
-
(2013)
Immunity
, vol.39
, pp. 782-795
-
-
Bindea, G.1
-
102
-
-
84883244497
-
Tumor-infiltrating B cells and T cells: Working together to promote patient survival
-
Nielsen, J.S., Nelson, B.H., Tumor-infiltrating B cells and T cells: Working together to promote patient survival. Oncoimmunology 1 (2012), 1623–1625.
-
(2012)
Oncoimmunology
, vol.1
, pp. 1623-1625
-
-
Nielsen, J.S.1
Nelson, B.H.2
-
103
-
-
85019477463
-
Tumor-infiltrating lymphocyte composition, organization and PD-1/PD–L1 expression are linked in breast cancer
-
Buisseret, L., et al. Tumor-infiltrating lymphocyte composition, organization and PD-1/PD–L1 expression are linked in breast cancer. Oncoimmunology, 6, 2017, e1257452.
-
(2017)
Oncoimmunology
, vol.6
, pp. e1257452
-
-
Buisseret, L.1
-
104
-
-
84962903666
-
Spatial distribution of B cells predicts prognosis in human pancreatic adenocarcinoma
-
Castino, G.F., et al. Spatial distribution of B cells predicts prognosis in human pancreatic adenocarcinoma. Oncoimmunology, 5, 2016, e1085147.
-
(2016)
Oncoimmunology
, vol.5
, pp. e1085147
-
-
Castino, G.F.1
-
105
-
-
84964567438
-
Tumor-infiltrating plasma cells are associated with tertiary lymphoid structures, cytolytic T-cell responses, and superior prognosis in ovarian cancer
-
Kroeger, D.R., et al. Tumor-infiltrating plasma cells are associated with tertiary lymphoid structures, cytolytic T-cell responses, and superior prognosis in ovarian cancer. Clin. Cancer Res. 22 (2016), 3005–3015.
-
(2016)
Clin. Cancer Res.
, vol.22
, pp. 3005-3015
-
-
Kroeger, D.R.1
-
106
-
-
84940121515
-
B cell-intrinsic IDO1 regulates humoral immunity to T cell-independent antigens
-
Shinde, R., et al. B cell-intrinsic IDO1 regulates humoral immunity to T cell-independent antigens. J. Immunol. 195 (2015), 2374–2382.
-
(2015)
J. Immunol.
, vol.195
, pp. 2374-2382
-
-
Shinde, R.1
-
107
-
-
84928177138
-
Regulatory B cells: origin, phenotype, and function
-
Rosser, E.C., Mauri, C., Regulatory B cells: origin, phenotype, and function. Immunity 42 (2015), 607–612.
-
(2015)
Immunity
, vol.42
, pp. 607-612
-
-
Rosser, E.C.1
Mauri, C.2
-
108
-
-
84925483168
-
Type I interferon: understanding its role in HIV pathogenesis and therapy
-
Bosinger, S.E., Utay, N.S., Type I interferon: understanding its role in HIV pathogenesis and therapy. Curr. HIV/AIDS Rep. 12 (2015), 41–53.
-
(2015)
Curr. HIV/AIDS Rep.
, vol.12
, pp. 41-53
-
-
Bosinger, S.E.1
Utay, N.S.2
-
109
-
-
84871797372
-
Pegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration
-
Azzoni, L., et al. Pegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration. J. Infect. Dis. 207 (2013), 213–222.
-
(2013)
J. Infect. Dis.
, vol.207
, pp. 213-222
-
-
Azzoni, L.1
-
110
-
-
84933277745
-
Type I interferons in anticancer immunity
-
Zitvogel, L., et al. Type I interferons in anticancer immunity. Nat. Rev. Immunol. 15 (2015), 405–414.
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 405-414
-
-
Zitvogel, L.1
-
111
-
-
84879689088
-
25 years of interferon-based treatment of chronic hepatitis C: an epoch coming to an end
-
Heim, M.H., 25 years of interferon-based treatment of chronic hepatitis C: an epoch coming to an end. Nat. Rev. Immunol. 13 (2013), 535–542.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 535-542
-
-
Heim, M.H.1
-
112
-
-
19044361835
-
Hepatic gene expression discriminates responders and nonresponders in treatment of chronic hepatitis C viral infection
-
Chen, L., et al. Hepatic gene expression discriminates responders and nonresponders in treatment of chronic hepatitis C viral infection. Gastroenterology 128 (2005), 1437–1444.
-
(2005)
Gastroenterology
, vol.128
, pp. 1437-1444
-
-
Chen, L.1
-
113
-
-
44349109098
-
Interferon signaling and treatment outcome in chronic hepatitis C
-
Sarasin-Filipowicz, M., et al. Interferon signaling and treatment outcome in chronic hepatitis C. Proc. Natl. Acad. Sci. U. S. A. 105 (2008), 7034–7039.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 7034-7039
-
-
Sarasin-Filipowicz, M.1
-
114
-
-
0345696854
-
Interferon alfa-2b combined with cytarabine versus interferon alone in chronic myelogenous leukemia. French Chronic Myeloid Leukemia Study Group
-
Guilhot, F., et al. Interferon alfa-2b combined with cytarabine versus interferon alone in chronic myelogenous leukemia. French Chronic Myeloid Leukemia Study Group. N. Engl. J. Med. 337 (1997), 223–229.
-
(1997)
N. Engl. J. Med.
, vol.337
, pp. 223-229
-
-
Guilhot, F.1
-
115
-
-
0025349897
-
Maintenance treatment with recombinant interferon alfa-2b in patients with multiple myeloma responding to conventional induction chemotherapy
-
Mandelli, F., et al. Maintenance treatment with recombinant interferon alfa-2b in patients with multiple myeloma responding to conventional induction chemotherapy. N. Engl. J. Med. 322 (1990), 1430–1434.
-
(1990)
N. Engl. J. Med.
, vol.322
, pp. 1430-1434
-
-
Mandelli, F.1
-
116
-
-
0027394227
-
Natural interferon-alpha in combination with melphalan/prednisone versus melphalan/prednisone in the treatment of multiple myeloma stages II and III: a randomized study from the Myeloma Group of Central Sweden
-
Osterborg, A., et al. Natural interferon-alpha in combination with melphalan/prednisone versus melphalan/prednisone in the treatment of multiple myeloma stages II and III: a randomized study from the Myeloma Group of Central Sweden. Blood 81 (1993), 1428–1434.
-
(1993)
Blood
, vol.81
, pp. 1428-1434
-
-
Osterborg, A.1
-
117
-
-
84921438337
-
Who benefits most from adjuvant interferon treatment for melanoma?
-
Gogas, H., et al. Who benefits most from adjuvant interferon treatment for melanoma?. Am. J. Ther. 22 (2015), 54–60.
-
(2015)
Am. J. Ther.
, vol.22
, pp. 54-60
-
-
Gogas, H.1
-
118
-
-
29144457523
-
Randomized trial of adjuvant intraperitoneal alpha-interferon in stage III ovarian cancer patients who have no evidence of disease after primary surgery and chemotherapy: an intergroup study
-
Alberts, D.S., et al. Randomized trial of adjuvant intraperitoneal alpha-interferon in stage III ovarian cancer patients who have no evidence of disease after primary surgery and chemotherapy: an intergroup study. Gynecol. Oncol. 100 (2006), 133–138.
-
(2006)
Gynecol. Oncol.
, vol.100
, pp. 133-138
-
-
Alberts, D.S.1
-
119
-
-
42749083267
-
Randomized phase 3 trial of interferon gamma-1b plus standard carboplatin/paclitaxel versus carboplatin/paclitaxel alone for first-line treatment of advanced ovarian and primary peritoneal carcinomas: results from a prospectively designed analysis of progression-free survival
-
Alberts, D.S., et al. Randomized phase 3 trial of interferon gamma-1b plus standard carboplatin/paclitaxel versus carboplatin/paclitaxel alone for first-line treatment of advanced ovarian and primary peritoneal carcinomas: results from a prospectively designed analysis of progression-free survival. Gynecol. Oncol. 109 (2008), 174–181.
-
(2008)
Gynecol. Oncol.
, vol.109
, pp. 174-181
-
-
Alberts, D.S.1
-
120
-
-
4344703324
-
Maintenance treatment with interferon for advanced ovarian cancer: results of the Northern and Yorkshire gynaecology group randomised phase III study
-
Hall, G.D., et al. Maintenance treatment with interferon for advanced ovarian cancer: results of the Northern and Yorkshire gynaecology group randomised phase III study. Br. J. Cancer 91 (2004), 621–626.
-
(2004)
Br. J. Cancer
, vol.91
, pp. 621-626
-
-
Hall, G.D.1
-
121
-
-
0021226287
-
A phase II study of recombinant alpha interferon in patients with recurrent or metastatic breast cancer
-
Muss, H.B., et al. A phase II study of recombinant alpha interferon in patients with recurrent or metastatic breast cancer. J. Clin. Oncol. 2 (1984), 1012–1016.
-
(1984)
J. Clin. Oncol.
, vol.2
, pp. 1012-1016
-
-
Muss, H.B.1
-
122
-
-
0021235552
-
Recombinant interferon in advanced breast cancer
-
Nethersell, A., et al. Recombinant interferon in advanced breast cancer. Br. J. Cancer 49 (1984), 615–620.
-
(1984)
Br. J. Cancer
, vol.49
, pp. 615-620
-
-
Nethersell, A.1
-
123
-
-
84910491603
-
A multiple-dose phase I trial of recombinant leukocyte A interferon in cancer patients
-
Sherwin, S.A., et al. A multiple-dose phase I trial of recombinant leukocyte A interferon in cancer patients. J. Am. Med. Assoc. 248 (1982), 2461–2466.
-
(1982)
J. Am. Med. Assoc.
, vol.248
, pp. 2461-2466
-
-
Sherwin, S.A.1
-
124
-
-
84896087235
-
Viruses for tumor therapy
-
Bell, J., McFadden, G., Viruses for tumor therapy. Cell Host Microbe 15 (2014), 260–265.
-
(2014)
Cell Host Microbe
, vol.15
, pp. 260-265
-
-
Bell, J.1
McFadden, G.2
-
125
-
-
84940403834
-
DNA-demethylating agents target colorectal cancer cells by inducing viral mimicry by endogenous transcripts
-
Roulois, D., et al. DNA-demethylating agents target colorectal cancer cells by inducing viral mimicry by endogenous transcripts. Cell 162 (2015), 961–973.
-
(2015)
Cell
, vol.162
, pp. 961-973
-
-
Roulois, D.1
-
126
-
-
84912089439
-
Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells
-
Ruffell, B., et al. Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells. Cancer Cell 26 (2014), 623–637.
-
(2014)
Cancer Cell
, vol.26
, pp. 623-637
-
-
Ruffell, B.1
-
127
-
-
79960929116
-
The role of IL-10 in regulating immunity to persistent viral infections
-
Wilson, E.B., Brooks, D.G., The role of IL-10 in regulating immunity to persistent viral infections. Curr. Top. Microbiol. Immunol. 350 (2011), 39–65.
-
(2011)
Curr. Top. Microbiol. Immunol.
, vol.350
, pp. 39-65
-
-
Wilson, E.B.1
Brooks, D.G.2
-
128
-
-
83455173552
-
IL-10 elicits IFNgamma-dependent tumor immune surveillance
-
Mumm, J.B., et al. IL-10 elicits IFNgamma-dependent tumor immune surveillance. Cancer Cell 20 (2011), 781–796.
-
(2011)
Cancer Cell
, vol.20
, pp. 781-796
-
-
Mumm, J.B.1
-
129
-
-
0037136303
-
Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody
-
Vicari, A.P., et al. Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody. J. Exp. Med. 196 (2002), 541–549.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 541-549
-
-
Vicari, A.P.1
-
130
-
-
84978513773
-
PEG-rIL-10 treatment decreases FoxP3(+) Tregs despite upregulation of intratumoral IDO
-
Chan, I.H., et al. PEG-rIL-10 treatment decreases FoxP3(+) Tregs despite upregulation of intratumoral IDO. Oncoimmunology, 5, 2016, e1197458.
-
(2016)
Oncoimmunology
, vol.5
, pp. e1197458
-
-
Chan, I.H.1
-
131
-
-
84901945177
-
Multifaceted activities of type I interferon are revealed by a receptor antagonist
-
Levin, D., et al. Multifaceted activities of type I interferon are revealed by a receptor antagonist. Sci. Signal., 7, 2014, ra50.
-
(2014)
Sci. Signal.
, vol.7
, pp. ra50
-
-
Levin, D.1
-
132
-
-
85008331088
-
Targeting type I interferon-mediated activation restores immune function in chronic HIV infection
-
Zhen, A., et al. Targeting type I interferon-mediated activation restores immune function in chronic HIV infection. J. Clin. Invest. 127 (2017), 260–268.
-
(2017)
J. Clin. Invest.
, vol.127
, pp. 260-268
-
-
Zhen, A.1
-
133
-
-
85008395064
-
Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs
-
Cheng, L., et al. Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs. J. Clin. Invest. 127 (2017), 269–279.
-
(2017)
J. Clin. Invest.
, vol.127
, pp. 269-279
-
-
Cheng, L.1
-
134
-
-
84892416698
-
Targeting the tumor microenvironment with interferon-beta bridges innate and adaptive immune responses
-
Yang, X., et al. Targeting the tumor microenvironment with interferon-beta bridges innate and adaptive immune responses. Cancer Cell 25 (2014), 37–48.
-
(2014)
Cancer Cell
, vol.25
, pp. 37-48
-
-
Yang, X.1
-
135
-
-
84983216790
-
Mutations associated with acquired resistance to PD-1 blockade in melanoma
-
Zaretsky, J.M., et al. Mutations associated with acquired resistance to PD-1 blockade in melanoma. N. Engl. J. Med. 375 (2016), 819–829.
-
(2016)
N. Engl. J. Med.
, vol.375
, pp. 819-829
-
-
Zaretsky, J.M.1
|