메뉴 건너뛰기




Volumn 211, Issue 5, 2014, Pages 961-974

Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection

Author keywords

[No Author keywords available]

Indexed keywords

HERMES ANTIGEN; INTERFERON; L SELECTIN;

EID: 84899746524     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20131556     Document Type: Article
Times cited : (134)

References (70)
  • 1
    • 0021225388 scopus 로고
    • Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice Role in suppression of cytotoxic T lymphocyte response and viral persistence
    • Ahmed, R., A. Salmi, L.D. Butler, J.M. Chiller, and M.B. Oldstone. 1984. Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence. J. Exp. Med. 160:521-540. http://dx.doi.org/10.1084/jem.160.2.521
    • (1984) J. Exp. Med. , vol.160 , pp. 521-540
    • Ahmed, R.1    Salmi, A.2    Butler, L.D.3    Chiller, J.M.4    Oldstone, M.B.5
  • 2
    • 16244409253 scopus 로고    scopus 로고
    • Interferons as pathogenic effectors in autoimmunity
    • Baccala, R., D.H. Kono, and A.N. Theofilopoulos. 2005. Interferons as pathogenic effectors in autoimmunity. Immunol. Rev. 204:9-26. http://dx.doi.org/10.1111/j.0105-2896.2005.00252.x
    • (2005) Immunol. Rev. , vol.204 , pp. 9-26
    • Baccala, R.1    Kono, D.H.2    Theofilopoulos, A.N.3
  • 3
    • 34748873441 scopus 로고    scopus 로고
    • Regulatory T cells and infection: a dangerous necessity
    • Belkaid, Y. 2007. Regulatory T cells and infection: a dangerous necessity. Nat. Rev. Immunol. 7:875-888. http://dx.doi.org/10.1038/nri2189
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 875-888
    • Belkaid, Y.1
  • 4
    • 67649138829 scopus 로고    scopus 로고
    • Regulatory T cells in the control of hostmicroorganism interactions*
    • Belkaid, Y., and K. Tarbell. 2009. Regulatory T cells in the control of hostmicroorganism interactions*. Annu. Rev. Immunol. 27:551-589. http://dx.doi.org/10.1146/annurev.immunol.021908.132723
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 551-589
    • Belkaid, Y.1    Tarbell, K.2
  • 5
    • 84856022105 scopus 로고    scopus 로고
    • Microbial infection-induced expansion of effector T cells overcomes the suppressive effects of regulatory T cells via an IL-2 deprivation mechanism
    • Benson, A., S. Murray, P. Divakar, N. Burnaevskiy, R. Pifer, J. Forman, and F. Yarovinsky. 2012. Microbial infection-induced expansion of effector T cells overcomes the suppressive effects of regulatory T cells via an IL-2 deprivation mechanism. J. Immunol. 188:800-810. http://dx.doi.org/10.4049/jimmunol.1100769
    • (2012) J. Immunol. , vol.188 , pp. 800-810
    • Benson, A.1    Murray, S.2    Divakar, P.3    Burnaevskiy, N.4    Pifer, R.5    Forman, J.6    Yarovinsky, F.7
  • 6
    • 33645857965 scopus 로고    scopus 로고
    • Increased hepatitis C virus (HCV)-specific CD4+CD25+ regulatory T lymphocytes and reduced HCV-specific CD4+ T cell response in HCV-infected patients with normal versus abnormal alanine aminotransferase levels
    • Bolacchi, F., A. Sinistro, C. Ciaprini, F. Demin, M. Capozzi, F.C. Carducci, C.M. Drapeau, G. Rocchi, and A. Bergamini. 2006. Increased hepatitis C virus (HCV)-specific CD4+CD25+ regulatory T lymphocytes and reduced HCV-specific CD4+ T cell response in HCV-infected patients with normal versus abnormal alanine aminotransferase levels. Clin. Exp. Immunol. 144:188-196. http://dx.doi.org/10.1111/j.1365-2249.2006.03048.x
    • (2006) Clin. Exp. Immunol. , vol.144 , pp. 188-196
    • Bolacchi, F.1    Sinistro, A.2    Ciaprini, C.3    Demin, F.4    Capozzi, M.5    Carducci, F.C.6    Drapeau, C.M.7    Rocchi, G.8    Bergamini, A.9
  • 7
    • 33645465526 scopus 로고    scopus 로고
    • Selective stimulation of T cell subsets with antibody-cytokine immune complexes
    • Boyman, O., M. Kovar, M.P. Rubinstein, C.D. Surh, and J. Sprent. 2006. Selective stimulation of T cell subsets with antibody-cytokine immune complexes. Science. 311:1924-1927. http://dx.doi.org/10.1126/science.1122927
    • (2006) Science. , vol.311 , pp. 1924-1927
    • Boyman, O.1    Kovar, M.2    Rubinstein, M.P.3    Surh, C.D.4    Sprent, J.5
  • 8
    • 0029799912 scopus 로고    scopus 로고
    • Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma
    • Bromberg, J.F., C.M. Horvath, Z. Wen, R.D. Schreiber, and J.E. Darnell Jr. 1996. Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma. Proc. Natl. Acad. Sci. USA. 93:7673-7678. http://dx.doi.org/10.1073/pnas.93.15.7673
    • (1996) Proc. Natl. Acad. Sci. USA. , vol.93 , pp. 7673-7678
    • Bromberg, J.F.1    Horvath, C.M.2    Wen, Z.3    Schreiber, R.D.4    Darnell Jr., J.E.5
  • 9
    • 7044247947 scopus 로고    scopus 로고
    • An immunomodulatory role for CD4+CD25+ regulatory T lymphocytes in hepatitis C virus infection
    • Cabrera, R., Z. Tu, Y. Xu, R.J. Firpi, H.R. Rosen, C. Liu, and D.R. Nelson. 2004. An immunomodulatory role for CD4+CD25+ regulatory T lymphocytes in hepatitis C virus infection. Hepatology. 40:1062-1071. http://dx.doi.org/10.1002/hep.20454
    • (2004) Hepatology. , vol.40 , pp. 1062-1071
    • Cabrera, R.1    Tu, Z.2    Xu, Y.3    Firpi, R.J.4    Rosen, H.R.5    Liu, C.6    Nelson, D.R.7
  • 10
    • 84856805188 scopus 로고    scopus 로고
    • IFN-? induces the proliferation of CD4+CD25+Foxp3+ regulatory T cells through upregulation of GITRL on dendritic cells in the treatment of multiple sclerosis
    • Chen, M., G. Chen, S. Deng, X. Liu, G.J. Hutton, and J. Hong. 2012. IFN-? induces the proliferation of CD4+CD25+Foxp3+ regulatory T cells through upregulation of GITRL on dendritic cells in the treatment of multiple sclerosis. J. Neuroimmunol. 242:39-46. http://dx.doi.org/10.1016/j.jneuroim.2011.10.014
    • (2012) J. Neuroimmunol. , vol.242 , pp. 39-46
    • Chen, M.1    Chen, G.2    Deng, S.3    Liu, X.4    Hutton, G.J.5    Hong, J.6
  • 11
    • 79959328032 scopus 로고    scopus 로고
    • ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6
    • Choi, Y.S., R. Kageyama, D. Eto, T.C. Escobar, R.J. Johnston, L. Monticelli, C. Lao, and S. Crotty. 2011. ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity. 34:932-946. http://dx.doi.org/10.1016/j.immuni.2011.03.023
    • (2011) Immunity. , vol.34 , pp. 932-946
    • Choi, Y.S.1    Kageyama, R.2    Eto, D.3    Escobar, T.C.4    Johnston, R.J.5    Monticelli, L.6    Lao, C.7    Crotty, S.8
  • 12
    • 33846005781 scopus 로고    scopus 로고
    • IL-15 and dermal fibroblasts induce proliferation of natural regulatory T cells isolated from human skin
    • Clark, R.A., and T.S. Kupper. 2007. IL-15 and dermal fibroblasts induce proliferation of natural regulatory T cells isolated from human skin. Blood. 109:194-202. http://dx.doi.org/10.1182/blood-2006-02-002873
    • (2007) Blood. , vol.109 , pp. 194-202
    • Clark, R.A.1    Kupper, T.S.2
  • 14
    • 84873160951 scopus 로고    scopus 로고
    • Differentiation and function of Foxp3+ effector regulatory T cells
    • Cretney, E., A. Kallies, and S.L. Nutt. 2013. Differentiation and function of Foxp3+ effector regulatory T cells. Trends Immunol. 34:74-80. http://dx.doi.org/10.1016/j.it.2012.11.002
    • (2013) Trends Immunol. , vol.34 , pp. 74-80
    • Cretney, E.1    Kallies, A.2    Nutt, S.L.3
  • 18
    • 28244447468 scopus 로고    scopus 로고
    • CD4+CD25+ T cells prevent the development of organ-specific autoimmune disease by inhibiting the differentiation of autoreactive effector T cells
    • DiPaolo, R.J., D.D. Glass, K.E. Bijwaard, and E.M. Shevach. 2005. CD4+CD25+ T cells prevent the development of organ-specific autoimmune disease by inhibiting the differentiation of autoreactive effector T cells. J. Immunol. 175:7135-7142.
    • (2005) J. Immunol , vol.175 , pp. 7135-7142
    • DiPaolo, R.J.1    Glass, D.D.2    Bijwaard, K.E.3    Shevach, E.M.4
  • 19
    • 30444458396 scopus 로고    scopus 로고
    • Suppressor activity and potency among regulatory T cells is discriminated by functionally active CD44
    • Firan, M., S. Dhillon, P. Estess, and M.H. Siegelman. 2006. Suppressor activity and potency among regulatory T cells is discriminated by functionally active CD44. Blood. 107:619-627. http://dx.doi.org/10.1182/blood-2005-06-2277
    • (2006) Blood. , vol.107 , pp. 619-627
    • Firan, M.1    Dhillon, S.2    Estess, P.3    Siegelman, M.H.4
  • 20
    • 77956913784 scopus 로고    scopus 로고
    • Foxp3+ CD4 regulatory T cells limit pulmonary immunopathology by modulating the CD8 T cell response during respiratory syncytial virus infection
    • Fulton, R.B., D.K. Meyerholz, and S.M. Varga. 2010. Foxp3+ CD4 regulatory T cells limit pulmonary immunopathology by modulating the CD8 T cell response during respiratory syncytial virus infection. J. Immunol. 185:2382-2392. http://dx.doi.org/10.4049/jimmunol.1000423
    • (2010) J. Immunol. , vol.185 , pp. 2382-2392
    • Fulton, R.B.1    Meyerholz, D.K.2    Varga, S.M.3
  • 21
    • 31544476539 scopus 로고    scopus 로고
    • Modulation of STAT1 protein levels: a mechanism shaping CD8 T-cell responses in vivo
    • Gil, M.P., R. Salomon, J. Louten, and C.A. Biron. 2006. Modulation of STAT1 protein levels: a mechanism shaping CD8 T-cell responses in vivo. Blood. 107:987-993. http://dx.doi.org/10.1182/blood-2005-07-2834
    • (2006) Blood. , vol.107 , pp. 987-993
    • Gil, M.P.1    Salomon, R.2    Louten, J.3    Biron, C.A.4
  • 22
    • 84868580741 scopus 로고    scopus 로고
    • Regulating type 1 IFN effects in CD8 T cells during viral infections: changing STAT4 and STAT1 expression for function
    • Gil, M.P., M.J. Ploquin, W.T. Watford, S.H. Lee, K. Kim, X. Wang, Y. Kanno, J.J. O'Shea, and C.A. Biron. 2012. Regulating type 1 IFN effects in CD8 T cells during viral infections: changing STAT4 and STAT1 expression for function. Blood. 120:3718-3728. http://dx.doi.org/10.1182/blood-2012-05-428672
    • (2012) Blood. , vol.120 , pp. 3718-3728
    • Gil, M.P.1    Ploquin, M.J.2    Watford, W.T.3    Lee, S.H.4    Kim, K.5    Wang, X.6    Kanno, Y.7    O'Shea, J.J.8    Biron, C.A.9
  • 23
    • 77955169480 scopus 로고    scopus 로고
    • Interferonalpha regulates the dynamic balance between human activated regulatory and effector T cells: implications for antiviral and autoimmune responses
    • Golding, A., A. Rosen, M. Petri, E. Akhter, and F. Andrade. 2010. Interferonalpha regulates the dynamic balance between human activated regulatory and effector T cells: implications for antiviral and autoimmune responses. Immunology. 131:107-117.
    • (2010) Immunology , vol.131 , pp. 107-117
    • Golding, A.1    Rosen, A.2    Petri, M.3    Akhter, E.4    Andrade, F.5
  • 24
    • 0024818822 scopus 로고
    • Intraepithelial lymphocytes Anatomical site, not T cell receptor form, dictates phenotype and function
    • Goodman, T., and L. Lefrancois. 1989. Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function. J. Exp. Med. 170:1569-1581. http://dx.doi.org/10.1084/jem.170.5.1569
    • (1989) J. Exp. Med. , vol.170 , pp. 1569-1581
    • Goodman, T.1    Lefrancois, L.2
  • 25
    • 40749084404 scopus 로고    scopus 로고
    • Suppression of mature dendritic cell function by regulatory T cells in vivo is abrogated by CD40 licensing
    • Hänig, J., and M.B. Lutz. 2008. Suppression of mature dendritic cell function by regulatory T cells in vivo is abrogated by CD40 licensing. J. Immunol. 180:1405-1413.
    • (2008) J. Immunol , vol.180 , pp. 1405-1413
    • Hänig, J.1    Lutz, M.B.2
  • 26
    • 33644837684 scopus 로고    scopus 로고
    • Cutting Edge: The direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection
    • Havenar-Daughton, C., G.A. Kolumam, and K. Murali-Krishna. 2006. Cutting Edge: The direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection. J. Immunol. 176:3315-3319.
    • (2006) J. Immunol , vol.176 , pp. 3315-3319
    • Havenar-Daughton, C.1    Kolumam, G.A.2    Murali-Krishna, K.3
  • 27
    • 2942692037 scopus 로고    scopus 로고
    • CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion
    • Herman, A.E., G.J. Freeman, D. Mathis, and C. Benoist. 2004. CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion. J. Exp. Med. 199:1479-1489. http://dx.doi.org/10.1084/jem.20040179
    • (2004) J. Exp. Med. , vol.199 , pp. 1479-1489
    • Herman, A.E.1    Freeman, G.J.2    Mathis, D.3    Benoist, C.4
  • 29
    • 0034887110 scopus 로고    scopus 로고
    • Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory
    • Homann, D., L. Teyton, and M.B. Oldstone. 2001. Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory. Nat. Med. 7:913-919. http://dx.doi.org/10.1038/90950
    • (2001) Nat. Med. , vol.7 , pp. 913-919
    • Homann, D.1    Teyton, L.2    Oldstone, M.B.3
  • 32
    • 24344478196 scopus 로고    scopus 로고
    • Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
    • Kolumam, G.A., S. Thomas, L.J. Thompson, J. Sprent, and K. Murali- Krishna. 2005. Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection. J. Exp. Med. 202:637-650. http://dx.doi.org/10.1084/jem.20050821
    • (2005) J. Exp. Med. , vol.202 , pp. 637-650
    • Kolumam, G.A.1    Thomas, S.2    Thompson, L.J.3    Sprent, J.4    Murali-Krishna, K.5
  • 33
    • 84862740015 scopus 로고    scopus 로고
    • Type I interferons maintain Foxp3 expression and T-regulatory cell functions under inflammatory conditions in mice
    • Lee, S.E., X. Li, J.C. Kim, J. Lee, J.M. González-Navajas, S.H. Hong, I.K. Park, J.H. Rhee, and E. Raz. 2012. Type I interferons maintain Foxp3 expression and T-regulatory cell functions under inflammatory conditions in mice. Gastroenterology. 143:145-154. http://dx.doi.org/10.1053/j.gastro.2012.03.042
    • (2012) Gastroenterology. , vol.143 , pp. 145-154
    • Lee, S.E.1    Li, X.2    Kim, J.C.3    Lee, J.4    González-Navajas, J.M.5    Hong, S.H.6    Park, I.K.7    Rhee, J.H.8    Raz, E.9
  • 34
    • 33749134189 scopus 로고    scopus 로고
    • Cutting edge: Paracrine, but not autocrine, IL-2 signaling is sustained during early antiviral CD4 T cell response
    • Long, M., and A.J. Adler. 2006. Cutting edge: Paracrine, but not autocrine, IL-2 signaling is sustained during early antiviral CD4 T cell response. J. Immunol. 177:4257-4261.
    • (2006) J. Immunol , vol.177 , pp. 4257-4261
    • Long, M.1    Adler, A.J.2
  • 36
    • 45849153869 scopus 로고    scopus 로고
    • Coordination of early protective immunity to viral infection by regulatory T cells
    • Lund, J.M., L. Hsing, T.T. Pham, and A.Y. Rudensky. 2008. Coordination of early protective immunity to viral infection by regulatory T cells. Science. 320:1220-1224. http://dx.doi.org/10.1126/science.1155209
    • (2008) Science. , vol.320 , pp. 1220-1224
    • Lund, J.M.1    Hsing, L.2    Pham, T.T.3    Rudensky, A.Y.4
  • 37
    • 37049029996 scopus 로고    scopus 로고
    • Quantitative PCR technique for detecting lymphocytic choriomeningitis virus in vivo
    • McCausland, M.M., and S. Crotty. 2008. Quantitative PCR technique for detecting lymphocytic choriomeningitis virus in vivo. J. Virol. Methods. 147:167-176. http://dx.doi.org/10.1016/j.jviromet.2007.08.025
    • (2008) J. Virol. Methods. , vol.147 , pp. 167-176
    • McCausland, M.M.1    Crotty, S.2
  • 38
    • 33745978399 scopus 로고    scopus 로고
    • Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation
    • Mempel, T.R., M.J. Pittet, K. Khazaie, W. Weninger, R. Weissleder, H. von Boehmer, and U.H. von Andrian. 2006. Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation. Immunity. 25:129-141. http://dx.doi.org/10.1016/j.immuni.2006.04.015
    • (2006) Immunity. , vol.25 , pp. 129-141
    • Mempel, T.R.1    Pittet, M.J.2    Khazaie, K.3    Weninger, W.4    Weissleder, R.5    von Boehmer, H.6    von Andrian, U.H.7
  • 39
    • 34447580869 scopus 로고    scopus 로고
    • Gut flora antigens are not important in the maintenance of regulatory T cell heterogeneity and homeostasis
    • Min, B., A. Thornton, S.M. Caucheteux, S.A. Younes, K. Oh, J. Hu-Li, and W.E. Paul. 2007. Gut flora antigens are not important in the maintenance of regulatory T cell heterogeneity and homeostasis. Eur. J. Immunol. 37:1916-1923. http://dx.doi.org/10.1002/eji.200737236
    • (2007) Eur. J. Immunol. , vol.37 , pp. 1916-1923
    • Min, B.1    Thornton, A.2    Caucheteux, S.M.3    Younes, S.A.4    Oh, K.5    Hu-Li, J.6    Paul, W.E.7
  • 40
    • 84868202435 scopus 로고    scopus 로고
    • Reduction of circulating regulatory T cells by intravenous high-dose interferon alfa-2b treatment in melanoma patients
    • Mozzillo, N., and P. Ascierto. 2012. Reduction of circulating regulatory T cells by intravenous high-dose interferon alfa-2b treatment in melanoma patients. Clin. Exp. Metastasis. 29:801-805. http://dx.doi.org/10.1007/s10585-012-9504-2
    • (2012) Clin. Exp. Metastasis. , vol.29 , pp. 801-805
    • Mozzillo, N.1    Ascierto, P.2
  • 41
    • 0028070714 scopus 로고
    • Functional role of type I and type II interferons in antiviral defense
    • Müller, U., U. Steinhoff, L.F. Reis, S. Hemmi, J. Pavlovic, R.M. Zinkernagel, and M. Aguet. 1994. Functional role of type I and type II interferons in antiviral defense. Science. 264:1918-1921. http://dx.doi.org/10.1126/science.8009221
    • (1994) Science. , vol.264 , pp. 1918-1921
    • Müller, U.1    Steinhoff, U.2    Reis, L.F.3    Hemmi, S.4    Pavlovic, J.5    Zinkernagel, R.M.6    Aguet, M.7
  • 42
    • 0032005477 scopus 로고    scopus 로고
    • Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection
    • Murali-Krishna, K., J.D. Altman, M. Suresh, D.J. Sourdive, A.J. Zajac, J.D. Miller, J. Slansky, and R. Ahmed. 1998. Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity. 8:177-187. http://dx.doi.org/10.1016/S1074-7613(00) 80470-7
    • (1998) Immunity. , vol.8 , pp. 177-187
    • Murali-Krishna, K.1    Altman, J.D.2    Suresh, M.3    Sourdive, D.J.4    Zajac, A.J.5    Miller, J.D.6    Slansky, J.7    Ahmed, R.8
  • 43
    • 73149090090 scopus 로고    scopus 로고
    • Effect of IFN-? therapy on the frequency and function of CD4+CD25+ regulatory T cells and Foxp3 gene expression in relapsing-remitting multiple sclerosis (RRMS): a preliminary study
    • Namdar, A., B. Nikbin, M. Ghabaee, A. Bayati, and M. Izad. 2010. Effect of IFN-? therapy on the frequency and function of CD4+CD25+ regulatory T cells and Foxp3 gene expression in relapsing-remitting multiple sclerosis (RRMS): a preliminary study. J. Neuroimmunol. 218:120-124. http://dx.doi.org/10.1016/j.jneuroim.2009.10.013
    • (2010) J. Neuroimmunol. , vol.218 , pp. 120-124
    • Namdar, A.1    Nikbin, B.2    Ghabaee, M.3    Bayati, A.4    Izad, M.5
  • 46
    • 77953375467 scopus 로고    scopus 로고
    • APC activation by IFN-? decreases regulatory T cell and enhances Th cell functions
    • Pace, L., S. Vitale, B. Dettori, C. Palombi, V. La Sorsa, F. Belardelli, E. Proietti, and G. Doria. 2010. APC activation by IFN-? decreases regulatory T cell and enhances Th cell functions. J. Immunol. 184:5969-5979. http://dx.doi.org/10.4049/jimmunol.0900526
    • (2010) J. Immunol. , vol.184 , pp. 5969-5979
    • Pace, L.1    Vitale, S.2    Dettori, B.3    Palombi, C.4    La Sorsa, V.5    Belardelli, F.6    Proietti, E.7    Doria, G.8
  • 47
    • 84867767000 scopus 로고    scopus 로고
    • Regulatory T cells increase the avidity of primary CD8+ T cell responses and promote memory
    • Pace, L., A. Tempez, C. Arnold-Schrauf, F. Lemaitre, P. Bousso, L. Fetler, T. Sparwasser, and S. Amigorena. 2012. Regulatory T cells increase the avidity of primary CD8+ T cell responses and promote memory. Science. 338:532-536. http://dx.doi.org/10.1126/science.1227049
    • (2012) Science. , vol.338 , pp. 532-536
    • Pace, L.1    Tempez, A.2    Arnold-Schrauf, C.3    Lemaitre, F.4    Bousso, P.5    Fetler, L.6    Sparwasser, T.7    Amigorena, S.8
  • 48
    • 0037436119 scopus 로고    scopus 로고
    • Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
    • Pasare, C., and R. Medzhitov. 2003. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science. 299:1033-1036. http://dx.doi.org/10.1126/science.1078231
    • (2003) Science. , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 50
    • 43049177588 scopus 로고    scopus 로고
    • Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system
    • Prinz, M., H. Schmidt, A. Mildner, K.P. Knobeloch, U.K. Hanisch, J. Raasch, D. Merkler, C. Detje, I. Gutcher, J. Mages, et al. 2008. Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity. 28:675-686. http://dx.doi.org/10.1016/j.immuni.2008.03.011
    • (2008) Immunity. , vol.28 , pp. 675-686
    • Prinz, M.1    Schmidt, H.2    Mildner, A.3    Knobeloch, K.P.4    Hanisch, U.K.5    Raasch, J.6    Merkler, D.7    Detje, C.8    Gutcher, I.9    Mages, J.10
  • 51
    • 80052143261 scopus 로고    scopus 로고
    • Increase in circulating CD4+CD25+Foxp3+ T cells in patients with Philadelphia-negative chronic myeloproliferative neoplasms during treatment with IFN-?
    • Riley, C.H., M.K. Jensen, M.K. Brimnes, H.C. Hasselbalch, O.W. Bjerrum, P.T. Straten, and I.M. Svane. 2011. Increase in circulating CD4+CD25+Foxp3+ T cells in patients with Philadelphia-negative chronic myeloproliferative neoplasms during treatment with IFN-?. Blood. 118:2170-2173. http://dx.doi.org/10.1182/blood-2011-03-340992
    • (2011) Blood. , vol.118 , pp. 2170-2173
    • Riley, C.H.1    Jensen, M.K.2    Brimnes, M.K.3    Hasselbalch, H.C.4    Bjerrum, O.W.5    Straten, P.T.6    Svane, I.M.7
  • 52
    • 79960489694 scopus 로고    scopus 로고
    • Foxp3+ regulatory T cell expansion required for sustaining pregnancy compromises host defense against prenatal bacterial pathogens
    • Rowe, J.H., J.M. Ertelt, M.N. Aguilera, M.A. Farrar, and S.S. Way. 2011. Foxp3+ regulatory T cell expansion required for sustaining pregnancy compromises host defense against prenatal bacterial pathogens. Cell Host Microbe. 10:54-64. http://dx.doi.org/10.1016/j.chom.2011.06.005
    • (2011) Cell Host Microbe. , vol.10 , pp. 54-64
    • Rowe, J.H.1    Ertelt, J.M.2    Aguilera, M.N.3    Farrar, M.A.4    Way, S.S.5
  • 53
    • 43949105866 scopus 로고    scopus 로고
    • Regulatory T cells and immune tolerance
    • Sakaguchi, S., T. Yamaguchi, T. Nomura, and M. Ono. 2008. Regulatory T cells and immune tolerance. Cell. 133:775-787. http://dx.doi.org/10.1016/j.cell.2008.05.009
    • (2008) Cell. , vol.133 , pp. 775-787
    • Sakaguchi, S.1    Yamaguchi, T.2    Nomura, T.3    Ono, M.4
  • 54
    • 4344657757 scopus 로고    scopus 로고
    • CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion
    • Sarween, N., A. Chodos, C. Raykundalia, M. Khan, A.K. Abbas, and L.S. Walker. 2004. CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion. J. Immunol. 173:2942-2951.
    • (2004) J. Immunol , vol.173 , pp. 2942-2951
    • Sarween, N.1    Chodos, A.2    Raykundalia, C.3    Khan, M.4    Abbas, A.K.5    Walker, L.S.6
  • 55
    • 0347480215 scopus 로고    scopus 로고
    • CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells
    • Serra, P., A. Amrani, J. Yamanouchi, B. Han, S. Thiessen, T. Utsugi, J. Verdaguer, and P. Santamaria. 2003. CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells. Immunity. 19:877-889. http://dx.doi.org/10.1016/S1074-7613(03)00327-3
    • (2003) Immunity. , vol.19 , pp. 877-889
    • Serra, P.1    Amrani, M.2    Yamanouchi, J.3    Han, B.4    Thiessen, S.5    Utsugi, T.6    Verdaguer, J.7    Santamaria, P.8
  • 56
    • 84879604666 scopus 로고    scopus 로고
    • Pathogenspecific Treg cells expand early during mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12
    • Shafiani, S., C. Dinh, J.M. Ertelt, A.O. Moguche, I. Siddiqui, K.S. Smigiel, P. Sharma, D.J. Campbell, S.S. Way, and K.B. Urdahl. 2013. Pathogenspecific Treg cells expand early during mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12. Immunity. 38:1261-1270. http://dx.doi.org/10.1016/j.immuni.2013.06.003
    • (2013) Immunity. , vol.38 , pp. 1261-1270
    • Shafiani, S.1    Dinh, C.2    Ertelt, J.M.3    Moguche, A.O.4    Siddiqui, I.5    Smigiel, K.S.6    Sharma, P.7    Campbell, D.J.8    Way, S.S.9    Urdahl, K.B.10
  • 58
    • 77952348017 scopus 로고    scopus 로고
    • Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS)
    • Simpson, T.R., S.A. Quezada, and J.P. Allison. 2010. Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS). Curr. Opin. Immunol. 22:326-332. http://dx.doi.org/10.1016/j.coi.2010.01.001
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 326-332
    • Simpson, T.R.1    Quezada, S.A.2    Allison, J.P.3
  • 59
    • 81055126124 scopus 로고    scopus 로고
    • Regulatory T cells inhibit acute IFN-? synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10
    • Sojka, D.K., and D.J. Fowell. 2011. Regulatory T cells inhibit acute IFN-? synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10. Proc. Natl. Acad. Sci. USA. 108:18336-18341. http://dx.doi.org/10.1073/pnas.1110566108
    • (2011) Proc. Natl. Acad. Sci. USA. , vol.108 , pp. 18336-18341
    • Sojka, D.K.1    Fowell, D.J.2
  • 60
    • 11844285731 scopus 로고    scopus 로고
    • Cutting edge: role of STAT1, STAT3, and STAT5 in IFN-αβ responses in T lymphocytes
    • Tanabe, Y., T. Nishibori, L. Su, R.M. Arduini, D.P. Baker, and M. David. 2005. Cutting edge: role of STAT1, STAT3, and STAT5 in IFN-αβ responses in T lymphocytes. J. Immunol. 174:609-613.
    • (2005) J. Immunol , vol.174 , pp. 609-613
    • Tanabe, Y.1    Nishibori, T.2    Su, L.3    Arduini, R.M.4    Baker, D.P.5    David, M.6
  • 61
    • 77956894327 scopus 로고    scopus 로고
    • Graded attenuation of TCR signaling elicits distinct autoimmune diseases by altering thymic T cell selection and regulatory T cell function
    • Tanaka, S., S. Maeda, M. Hashimoto, C. Fujimori, Y. Ito, S. Teradaira, K. Hirota, H. Yoshitomi, T. Katakai, A. Shimizu, et al. 2010. Graded attenuation of TCR signaling elicits distinct autoimmune diseases by altering thymic T cell selection and regulatory T cell function. J. Immunol. 185:2295-2305. http://dx.doi.org/10.4049/jimmunol.1000848
    • (2010) J. Immunol. , vol.185 , pp. 2295-2305
    • Tanaka, S.1    Maeda, S.2    Hashimoto, M.3    Fujimori, C.4    Ito, Y.5    Teradaira, S.6    Hirota, K.7    Yoshitomi, H.8    Katakai, T.9    Shimizu, A.10
  • 64
    • 17644402442 scopus 로고    scopus 로고
    • Type I interferons (?/?) in immunity and autoimmunity
    • Theofilopoulos, A.N., R. Baccala, B. Beutler, and D.H. Kono. 2005. Type I interferons (?/?) in immunity and autoimmunity. Annu. Rev. Immunol. 23:307-335. http://dx.doi.org/10.1146/annurev.immunol.23.021704.115843
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 307-335
    • Theofilopoulos, A.N.1    Baccala, R.2    Beutler, B.3    Kono, D.H.4
  • 65
    • 77957745555 scopus 로고    scopus 로고
    • Type I interferon: friend or foe?
    • Trinchieri, G. 2010. Type I interferon: friend or foe? J. Exp. Med. 207:2053-2063. http://dx.doi.org/10.1084/jem.20101664
    • (2010) J. Exp. Med. , vol.207 , pp. 2053-2063
    • Trinchieri, G.1
  • 66
    • 33745224089 scopus 로고    scopus 로고
    • Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells
    • Williams, M.A., A.J. Tyznik, and M.J. Bevan. 2006. Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells. Nature. 441:890-893. http://dx.doi.org/10.1038/nature04790
    • (2006) Nature. , vol.441 , pp. 890-893
    • Williams, M.A.1    Tyznik, A.J.2    Bevan, M.J.3
  • 68
    • 73349102477 scopus 로고    scopus 로고
    • IL-15 promotes regulatory T cell function and protects against diabetes development in NKdepleted NOD mice
    • Xia, J., W. Liu, B. Hu, Z. Tian, and Y. Yang. 2010. IL-15 promotes regulatory T cell function and protects against diabetes development in NKdepleted NOD mice. Clin. Immunol. 134:130-139. http://dx.doi.org/10.1016/j.clim.2009.09.011
    • (2010) Clin. Immunol. , vol.134 , pp. 130-139
    • Xia, J.1    Liu, W.2    Hu, B.3    Tian, Z.4    Yang, Y.5
  • 69
    • 0032076635 scopus 로고    scopus 로고
    • Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15
    • Zhang, X., S. Sun, I. Hwang, D.F. Tough, and J. Sprent. 1998. Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15. Immunity. 8:591-599. http://dx.doi.org/10.1016/S1074-7613(00)80564-6
    • (1998) Immunity. , vol.8 , pp. 591-599
    • Zhang, X.1    Sun, S.2    Hwang, I.3    Tough, D.F.4    Sprent, J.5
  • 70
    • 79961139920 scopus 로고    scopus 로고
    • IFN-?- and IL-10-expressing virus epitope-specific Foxp3+ T reg cells in the central nervous system during encephalomyelitis
    • Zhao, J., J. Zhao, C. Fett, K. Trandem, E. Fleming, and S. Perlman. 2011. IFN-?- and IL-10-expressing virus epitope-specific Foxp3+ T reg cells in the central nervous system during encephalomyelitis. J. Exp. Med. 208:1571-1577. http://dx.doi.org/10.1084/jem.20110236
    • (2011) J. Exp. Med. , vol.208 , pp. 1571-1577
    • Zhao, J.1    Zhao, J.2    Fett, C.3    Trandem, K.4    Fleming, E.5    Perlman, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.