메뉴 건너뛰기




Volumn 5, Issue 1, 2017, Pages 42-51

Bortezomib relieves immune tolerance in nasopharyngeal carcinoma via STAT1 suppression and indoleamine 2,3-dioxygenase downregulation

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; GAMMA INTERFERON; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOLEAMINE 2,3 DIOXYGENASE; INTERFERON REGULATORY FACTOR 1; STAT1 PROTEIN; ANTINEOPLASTIC AGENT; PROTEIN BINDING;

EID: 85016122182     PISSN: 23266066     EISSN: 23266074     Source Type: Journal    
DOI: 10.1158/2326-6066.CIR-16-0102     Document Type: Article
Times cited : (28)

References (37)
  • 2
    • 73249117452 scopus 로고    scopus 로고
    • Expression of indoleamine 2,3-dioxygenase in nasopharyngeal carcinoma impairs the cytolytic function of peripheral blood lymphocytes
    • Liu P, Xie BL, Cai SH, He YW, Zhang G, Yi YM, et al. Expression of indoleamine 2,3-dioxygenase in nasopharyngeal carcinoma impairs the cytolytic function of peripheral blood lymphocytes. BMC Cancer 2009; 9:416.
    • (2009) BMC Cancer , vol.9 , pp. 416
    • Liu, P.1    Xie, B.L.2    Cai, S.H.3    He, Y.W.4    Zhang, G.5    Yi, Y.M.6
  • 3
    • 78649389922 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma
    • Chan AT. Nasopharyngeal carcinoma. Ann Oncol 2010;21(Suppl 7): vii308-312.
    • (2010) Ann Oncol , vol.21 , pp. 308-312
    • Chan, A.T.1
  • 6
    • 63849262293 scopus 로고    scopus 로고
    • Enhancing the in vivo expansion of adoptively transferred EBV-specific CTL with lymphodepleting CD45 monoclonal antibodies in NPC patients
    • Louis CU, Straathof K, Bollard CM, Gerken C, Huls MH, Gresik MV, et al. Enhancing the in vivo expansion of adoptively transferred EBV-specific CTL with lymphodepleting CD45 monoclonal antibodies in NPC patients. Blood 2009;113:2442-50.
    • (2009) Blood , vol.113 , pp. 2442-2450
    • Louis, C.U.1    Straathof, K.2    Bollard, C.M.3    Gerken, C.4    Huls, M.H.5    Gresik, M.V.6
  • 7
    • 77649239189 scopus 로고    scopus 로고
    • Immunogenicity and efficacy of aDNA vaccine encoding a human anti-idiotype single chain antibody against nasopharyngeal carcinoma
    • Luo C, Wang JJ, Li YH, Hu JY, Li GC. Immunogenicity and efficacy of aDNA vaccine encoding a human anti-idiotype single chain antibody against nasopharyngeal carcinoma. Vaccine 2010;28:2769-74.
    • (2010) Vaccine , vol.28 , pp. 2769-2774
    • Luo, C.1    Wang, J.J.2    Li, Y.H.3    Hu, J.Y.4    Li, G.C.5
  • 8
    • 84920545991 scopus 로고    scopus 로고
    • Cancer immunotherapy and breaking immune tolerance: New approaches to an old challenge
    • Makkouk A, Weiner GJ. Cancer immunotherapy and breaking immune tolerance: New approaches to an old challenge. Cancer Res 2015;75:5-10.
    • (2015) Cancer Res , vol.75 , pp. 5-10
    • Makkouk, A.1    Weiner, G.J.2
  • 9
    • 84944463730 scopus 로고    scopus 로고
    • Curcumin combined with FAPalphac vaccine elicits effective antitumor response by targeting indolamine-2,3-dioxygenase and inhibiting EMT induced by TNF-alpha in melanoma
    • Jiang GM, Xie WY, Wang HS, Du J, Wu BP, Xu W, et al. Curcumin combined with FAPalphac vaccine elicits effective antitumor response by targeting indolamine-2,3-dioxygenase and inhibiting EMT induced by TNF-alpha in melanoma. Oncotarget 2015;6:25932-42.
    • (2015) Oncotarget , vol.6 , pp. 25932-25942
    • Jiang, G.M.1    Xie, W.Y.2    Wang, H.S.3    Du, J.4    Wu, B.P.5    Xu, W.6
  • 10
    • 42149187760 scopus 로고    scopus 로고
    • Apoptotic cells induce dendritic cellmediated suppression via interferon-gamma-induced IDO
    • Williams CA, Harry RA, McLeod JD. Apoptotic cells induce dendritic cellmediated suppression via interferon-gamma-induced IDO. Immunology 2008;124:89-101.
    • (2008) Immunology , vol.124 , pp. 89-101
    • Williams, C.A.1    Harry, R.A.2    McLeod, J.D.3
  • 11
    • 0142137237 scopus 로고    scopus 로고
    • Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
    • Uyttenhove C, Pilotte L, Theate I, Stroobant V, Colau D, Parmentier N, et al. Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase. Nat Med 2003;9: 1269-74.
    • (2003) Nat Med , vol.9 , pp. 1269-1274
    • Uyttenhove, C.1    Pilotte, L.2    Theate, I.3    Stroobant, V.4    Colau, D.5    Parmentier, N.6
  • 12
    • 77957286502 scopus 로고    scopus 로고
    • Sodium butyrate down-regulation of indoleamine 2, 3-dioxygenase at the transcriptional and post-transcriptional levels
    • Jiang GM, He YW, Fang R, Zhang G, Zeng J, Yi YM, et al. Sodium butyrate down-regulation of indoleamine 2, 3-dioxygenase at the transcriptional and post-transcriptional levels. Int J Biochem Cell Biol 2010;42:1840-6.
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 1840-1846
    • Jiang, G.M.1    He, Y.W.2    Fang, R.3    Zhang, G.4    Zeng, J.5    Yi, Y.M.6
  • 13
    • 34248173331 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase and tumor-induced tolerance
    • Munn DH, Mellor AL. Indoleamine 2,3-dioxygenase and tumor-induced tolerance. J Clin Invest 2007;117:1147-54.
    • (2007) J Clin Invest , vol.117 , pp. 1147-1154
    • Munn, D.H.1    Mellor, A.L.2
  • 14
    • 84947967487 scopus 로고    scopus 로고
    • Prognostic value of indoleamine 2,3-dioxygenase activity and expression in nasopharyngeal carcinoma
    • Ben-Haj-Ayed A, Moussa A, Ghedira R, Gabbouj S, Miled S, Bouzid N, et al. Prognostic value of indoleamine 2,3-dioxygenase activity and expression in nasopharyngeal carcinoma. Immunol Lett 2016;169:23-32.
    • (2016) Immunol Lett , vol.169 , pp. 23-32
    • Ben-Haj-Ayed, A.1    Moussa, A.2    Ghedira, R.3    Gabbouj, S.4    Miled, S.5    Bouzid, N.6
  • 15
    • 0038215374 scopus 로고    scopus 로고
    • Tolerance, DCs and tryptophan: Much ado about IDO
    • Grohmann U, Fallarino F, Puccetti P. Tolerance, DCs and tryptophan: Much ado about IDO. Trends Immunol 2003;24:242-8.
    • (2003) Trends Immunol , vol.24 , pp. 242-248
    • Grohmann, U.1    Fallarino, F.2    Puccetti, P.3
  • 16
    • 84885176242 scopus 로고    scopus 로고
    • Sodium butyrate inhibits interferon-gamma induced indoleamine 2,3-dioxygenase expression via STAT1 in nasopharyngeal carcinoma cells
    • He YW, Wang HS, Zeng J, Fang X, Chen HY, Du J, et al. Sodium butyrate inhibits interferon-gamma induced indoleamine 2,3-dioxygenase expression via STAT1 in nasopharyngeal carcinoma cells. Life Sci 2013; 93:509-15.
    • (2013) Life Sci , vol.93 , pp. 509-515
    • He, Y.W.1    Wang, H.S.2    Zeng, J.3    Fang, X.4    Chen, H.Y.5    Du, J.6
  • 17
    • 77951718214 scopus 로고    scopus 로고
    • Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity
    • Liu X, Shin N, Koblish HK, Yang G, Wang Q, Wang K, et al. Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity. Blood 2010;115:3520-30.
    • (2010) Blood , vol.115 , pp. 3520-3530
    • Liu, X.1    Shin, N.2    Koblish, H.K.3    Yang, G.4    Wang, Q.5    Wang, K.6
  • 18
    • 76649088968 scopus 로고    scopus 로고
    • Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors
    • Koblish HK, Hansbury MJ, Bowman KJ, Yang G, Neilan CL, Haley PJ, et al. Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors. Mol Cancer Ther 2010; 9:489-98.
    • (2010) Mol Cancer Ther , vol.9 , pp. 489-498
    • Koblish, H.K.1    Hansbury, M.J.2    Bowman, K.J.3    Yang, G.4    Neilan, C.L.5    Haley, P.J.6
  • 19
    • 84892157282 scopus 로고    scopus 로고
    • Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase
    • Iversen TZ, Engell-Noerregaard L, Ellebaek E, Andersen R, Larsen SK, Bjoern J, et al. Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase. Clin Cancer Res 2014; 20:221-32.
    • (2014) Clin Cancer Res , vol.20 , pp. 221-232
    • Iversen, T.Z.1    Engell-Noerregaard, L.2    Ellebaek, E.3    Andersen, R.4    Larsen, S.K.5    Bjoern, J.6
  • 22
    • 0038189917 scopus 로고    scopus 로고
    • Rationale for the treatment of solid tumorswith the proteasome inhibitor bortezomib
    • Cusack JC. Rationale for the treatment of solid tumorswith the proteasome inhibitor bortezomib. Cancer Treat Rev 2003;29Suppl 1:21-31.
    • (2003) Cancer Treat Rev , vol.29 , pp. 21-31
    • Cusack, J.C.1
  • 23
    • 84877652831 scopus 로고    scopus 로고
    • Bortezomib and SAHA synergistically induce ROS-driven caspase-dependent apoptosis of nasopharyngeal carcinoma and block replication of Epstein-Barr virus
    • Hui KF, Lam BH, Ho DN, Tsao SW, Chiang AK. Bortezomib and SAHA synergistically induce ROS-driven caspase-dependent apoptosis of nasopharyngeal carcinoma and block replication of Epstein-Barr virus. Mol Cancer Ther 2013;12:747-58.
    • (2013) Mol Cancer Ther , vol.12 , pp. 747-758
    • Hui, K.F.1    Lam, B.H.2    Ho, D.N.3    Tsao, S.W.4    Chiang, A.K.5
  • 24
    • 33645776929 scopus 로고    scopus 로고
    • Immunosensitization of tumor cells to dendritic cell-activated immune responses with the proteasome inhibitor bortezomib (PS-341, Velcade)
    • Schumacher LY, Vo DD, Garban HJ, Comin-Anduix B, Owens SK, Dissette VB, et al. Immunosensitization of tumor cells to dendritic cell-activated immune responses with the proteasome inhibitor bortezomib (PS-341, Velcade). J Immunol 2006;176:4757-65.
    • (2006) J Immunol , vol.176 , pp. 4757-4765
    • Schumacher, L.Y.1    Vo, D.D.2    Garban, H.J.3    Comin-Anduix, B.4    Owens, S.K.5    Dissette, V.B.6
  • 25
    • 84898813745 scopus 로고    scopus 로고
    • IKKalpha restoration via EZH2 suppression induces nasopharyngeal carcinoma differentiation
    • Yan M, Zhang Y, He B, Xiang J, Wang ZF, Zheng FM, et al. IKKalpha restoration via EZH2 suppression induces nasopharyngeal carcinoma differentiation. Nat Commun 2014;5:3661.
    • (2014) Nat Commun , vol.5 , pp. 3661
    • Yan, M.1    Zhang, Y.2    He, B.3    Xiang, J.4    Wang, Z.F.5    Zheng, F.M.6
  • 26
    • 18844457095 scopus 로고    scopus 로고
    • Mechanisms of type-I-and type-II-interferon-mediated signalling
    • Platanias LC. Mechanisms of type-I-and type-II-interferon-mediated signalling. Nat Rev Immunol 2005;5:375-86.
    • (2005) Nat Rev Immunol , vol.5 , pp. 375-386
    • Platanias, L.C.1
  • 27
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell JE Jr, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994;264:1415-21.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell, J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 28
    • 0030035226 scopus 로고    scopus 로고
    • Cooperative role of interferon regulatory factor 1 and p91 (STAT1) response elements in interferon-gammainducible expression of human indoleamine 2,3-dioxygenase gene
    • Chon SY, Hassanain HH, Gupta SL. Cooperative role of interferon regulatory factor 1 and p91 (STAT1) response elements in interferon-gammainducible expression of human indoleamine 2,3-dioxygenase gene. J Biol Chem 1996;271:17247-52.
    • (1996) J Biol Chem , vol.271 , pp. 17247-17252
    • Chon, S.Y.1    Hassanain, H.H.2    Gupta, S.L.3
  • 29
    • 0025222683 scopus 로고
    • Regulation of indoleamine 2,3-dioxygenase gene expression in human fibroblasts by interferon-gamma. Upstream control region discriminates between interferon-gamma and interferon-alpha
    • Dai W, Gupta SL. Regulation of indoleamine 2,3-dioxygenase gene expression in human fibroblasts by interferon-gamma. Upstream control region discriminates between interferon-gamma and interferon-alpha. J Biol Chem 1990;265:19871-7.
    • (1990) J Biol Chem , vol.265 , pp. 19871-19877
    • Dai, W.1    Gupta, S.L.2
  • 31
    • 12144251098 scopus 로고    scopus 로고
    • The role of IFNgamma and TNF-alpharesponsive regulatory elements in the synergistic induction of indoleamine dioxygenase
    • Robinson CM, Hale PT, Carlin JM. The role of IFNgamma and TNF-alpharesponsive regulatory elements in the synergistic induction of indoleamine dioxygenase. J Interferon Cytokine Res 2005;25:20-30.
    • (2005) J Interferon Cytokine Res , vol.25 , pp. 20-30
    • Robinson, C.M.1    Hale, P.T.2    Carlin, J.M.3
  • 32
    • 0029041430 scopus 로고
    • Involvement of two regulatory elements in interferon-gamma-regulated expression of human indoleamine 2,3-dioxygenase gene
    • Chon SY, Hassanain HH, Pine R, Gupta SL. Involvement of two regulatory elements in interferon-gamma-regulated expression of human indoleamine 2,3-dioxygenase gene. J Interferon Cytokine Res 1995;15:517-26.
    • (1995) J Interferon Cytokine Res , vol.15 , pp. 517-526
    • Chon, S.Y.1    Hassanain, H.H.2    Pine, R.3    Gupta, S.L.4
  • 33
    • 26844452967 scopus 로고    scopus 로고
    • Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapy
    • Boccadoro M, Morgan G, Cavenagh J. Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapy. Cancer Cell Int 2005;5:18.
    • (2005) Cancer Cell Int , vol.5 , pp. 18
    • Boccadoro, M.1    Morgan, G.2    Cavenagh, J.3
  • 34
    • 0036680037 scopus 로고    scopus 로고
    • Preclinical and clinical evaluation of proteasome inhibitor PS- 341 for the treatment of cancer
    • Adams J. Preclinical and clinical evaluation of proteasome inhibitor PS- 341 for the treatment of cancer. Curr Opin Chem Biol 2002;6:493-500.
    • (2002) Curr Opin Chem Biol , vol.6 , pp. 493-500
    • Adams, J.1
  • 35
    • 84893724480 scopus 로고    scopus 로고
    • Association of response endpoints with survival outcomes in multiple myeloma
    • Lonial S, Anderson KC. Association of response endpoints with survival outcomes in multiple myeloma. Leukemia 2014;28:258-68.
    • (2014) Leukemia , vol.28 , pp. 258-268
    • Lonial, S.1    Anderson, K.C.2
  • 36
    • 79951702955 scopus 로고    scopus 로고
    • Bortezomib as the first proteasome inhibitor anticancer drug: Current status and future perspectives
    • Chen D, Frezza M, Schmitt S, Kanwar J, Dou QP. Bortezomib as the first proteasome inhibitor anticancer drug: current status and future perspectives. Curr Cancer Drug Targets 2011;11:239-53.
    • (2011) Curr Cancer Drug Targets , vol.11 , pp. 239-253
    • Chen, D.1    Frezza, M.2    Schmitt, S.3    Kanwar, J.4    Dou, Q.P.5
  • 37
    • 0034902354 scopus 로고    scopus 로고
    • Novel proteasome inhibitor PS-341 inhibits activation of nuclear factorkappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma
    • Sunwoo JB, Chen Z, Dong G, Yeh N, Crowl Bancroft C, Sausville E, et al. Novel proteasome inhibitor PS-341 inhibits activation of nuclear factorkappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma. Clin Cancer Res 2001;7:1419-28.
    • (2001) Clin Cancer Res , vol.7 , pp. 1419-1428
    • Sunwoo, J.B.1    Chen, Z.2    Dong, G.3    Yeh, N.4    Crowl Bancroft, C.5    Sausville, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.