Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape

Nature Medicine

Volumn 18, Issue 8, 2012, Pages 1224-1231

  Bidwell, Bradley N ^a,b   Slaney, Clare Y ^a,b   Withana, Nimali P ^a,b   Forster, Sam ^c   Cao, Yuan ^a,b   Loi, Sherene ^d   Andrews, Daniel ^a,b   Mikeska, Thomas ^a,b   Mangan, Niamh E ^c   Samarajiwa, Shamith A ^c,e   De Weerd, Nicole A ^c   Gould, Jodee ^c   Argani, Pedram ^f   Müller, Andreas ^a,b   Smyth, Mark J ^a,b   Anderson, Robin L ^a,b   Hertzog, Paul J ^c   Parker, Belinda S ^a,b  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c MONASH UNIVERSITY   (Australia)

^d JULES BORDET INSTITUTE   (Belgium)

^e IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^f DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CD11B ANTIGEN; INTERFERON; INTERFERON REGULATORY FACTOR 7; INTERFERON REGULATORY FACTOR 9; STAT1 PROTEIN; STAT2 PROTEIN; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE METASTASIS; BREAST CANCER; CANCER CELL; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CELLULAR IMMUNITY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN TISSUE; INNATE IMMUNITY; INTRACELLULAR SIGNALING; MAJOR CLINICAL STUDY; METASTASIS FREE SURVIVAL; MOUSE; NATURAL KILLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOCYTE; PRIORITY JOURNAL; SPINE METASTASIS; SURVIVAL TIME;

ANIMALS; BREAST NEOPLASMS; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; IMMUNOLOGIC SURVEILLANCE; INTERFERON REGULATORY FACTOR-7; INTERFERON-ALPHA; INTERFERON-STIMULATED GENE FACTOR 3, GAMMA SUBUNIT; KILLER CELLS, NATURAL; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; MICE, INBRED NOD; MICE, SCID; NEOPLASM METASTASIS; NEOPLASM PROTEINS; RECEPTORS, INTERFERON; RECOMBINANT PROTEINS; SEVERE COMBINED IMMUNODEFICIENCY; T-LYMPHOCYTE SUBSETS; TUMOR ESCAPE;

MUS;

EID: 84864654660     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2830     Document Type: Article

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