Kososan, a Kampo medicine, prevents a social avoidance behavior and attenuates neuroinflammation in socially defeated mice

Journal of Neuroinflammation

Volumn 14, Issue 1, 2017, Pages

  Ito, Naoki ^a   Hirose, Eiji ^a   Ishida, Tatsuya ^a   Hori, Atsushi ^a   Nagai, Takayuki ^a   Kobayashi, Yoshinori ^a   Kiyohara, Hiroaki ^a   Oikawa, Tetsuro ^a   Hanawa, Toshihiko ^a   Odaguchi, Hiroshi ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Antidepressant like effect; Anxiety; Chronic social defeat stress; Depression; Kampo; Kososan; Microglia; Neurogenesis; Neuroinflammation

Indexed keywords

KAMPO; KOSOSAN EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG; AUTACOID; HERBACEOUS AGENT; KOSO-SAN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DOWN REGULATION; DRUG SYNTHESIS; HIPPOCAMPUS; IMMUNOCOMPETENT CELL; MALE; MENTAL STRESS; MICROGLIA; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NERVOUS SYSTEM INFLAMMATION; NEUROMODULATION; NONHUMAN; PHENOTYPE; SOCIAL AVOIDANCE BEHAVIOR; SOCIAL BEHAVIOR; SOCIAL STRESS; TREATMENT DURATION; ANIMAL; ANTAGONISTS AND INHIBITORS; AVOIDANCE BEHAVIOR; C57BL MOUSE; DRUG EFFECTS; DRUG THERAPY; ISOLATION AND PURIFICATION; KAMPO MEDICINE; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANIMALS; AVOIDANCE LEARNING; DRUGS, CHINESE HERBAL; HIPPOCAMPUS; INFLAMMATION MEDIATORS; MALE; MEDICINE, KAMPO; MICE; MICE, INBRED C57BL; PLANT EXTRACTS; SOCIAL BEHAVIOR; STRESS, PSYCHOLOGICAL;

EID: 85018945665     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-017-0876-8     Document Type: Article

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