Defeating the fear: New insights into the neurobiology of stress susceptibility

Experimental Neurology

Volumn 261, Issue , 2014, Pages 412-416

  Krishnan, Vaishnav ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; GLUCOCORTICOID RECEPTOR; HEAT SHOCK PROTEIN 90; PROTEIN C FOS;

BASOLATERAL AMYGDALA; BRAIN ELECTROPHYSIOLOGY; BRAIN FUNCTION; DEPRESSION; DISEASE PREDISPOSITION; DOPAMINERGIC SYSTEM; DOWN REGULATION; FEAR; HIPPOCAMPUS; HUMAN; MENTAL STRESS; NERVOUS SYSTEM DEVELOPMENT; NEUROBIOLOGY; NONHUMAN; NOTE; PANIC; POSTTRAUMATIC STRESS DISORDER; PROTEIN FUNCTION; SEROTONINERGIC SYSTEM; SIGNAL TRANSDUCTION; SOCIAL AVOIDANCE BEHAVIOR; STRESS; UPREGULATION; ANIMAL; BRAIN; CONDITIONING; ETIOLOGY; METABOLISM; MOUSE; PATHOLOGY; PSYCHOLOGY;

ANIMALS; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CONDITIONING (PSYCHOLOGY); DISEASE SUSCEPTIBILITY; FEAR; HUMANS; MICE; NEUROBIOLOGY; STRESS, PSYCHOLOGICAL;

EID: 84905485757     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2014.05.012     Document Type: Note

References (42)

1. Berton O., McClung C.A., Dileone R.J., Krishnan V., Renthal W., Russo S.J., Graham D., Tsankova N.M., Bolanos C.A., Rios M., Monteggia L.M., Self D.W., Nestler E.J. Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science 2006, 311(5762):864-868.
2. Blechert J., Michael T., Grossman P., Lajtman M., Wilhelm F.H. Autonomic and respiratory characteristics of posttraumatic stress disorder and panic disorder. Psychosom. Med. 2007, 69(9):935-943.
3. Bocchio-Chiavetto L., Bagnardi V., Zanardini R., Molteni R., Nielsen M.G., Placentino A., Giovannini C., Rillosi L., Ventriglia M., Riva M.A., Gennarelli M. Serum and plasma BDNF levels in major depression: a replication study and meta-analyses. World J. Biol. Psychiatry 2010, 11(6):763-773.
4. Cao J.L., Covington H.E., Friedman A.K., Wilkinson M.B., Walsh J.J., Cooper D.C., Nestler E.J., Han M.H. Mesolimbic dopamine neurons in the brain reward circuit mediate susceptibility to social defeat and antidepressant action. J. Neurosci. 2010, 30(49):16453-16458.
5. Challis C., Boulden J., Veerakumar A., Espallergues J., Vassoler F.M., Pierce R.C., Beck S.G., Berton O. Raphe GABAergic neurons mediate the acquisition of avoidance after social defeat. J. Neurosci. 2013, 33(35):13978-13988. (13988a).
6. Chang C.H., Grace A.A. Amygdala beta-noradrenergic receptors modulate delayed downregulation of dopamine activity following restraint. J. Neurosci. 2013, 33(4):1441-1450.
7. Chaudhury D., Walsh J.J., Friedman A.K., Juarez B., Ku S.M., Koo J.W., Ferguson D., Tsai H.C., Pomeranz L., Christoffel D.J., Nectow A.R., Ekstrand M., Domingos A., Mazei-Robison M.S., Mouzon E., Lobo M.K., Neve R.L., Friedman J.M., Russo S.J., Deisseroth K., Nestler E.J., Han M.H. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature 2013, 493(7433):532-536.
8. Chou D., Huang C.C., Hsu K.S. Brain-derived neurotrophic factor in the amygdala mediates susceptibility to fear conditioning. Exp. Neurol 2014, 255:19-29. (Electronic publication ahead of print 2014 Feb 25). 10.1016/j.expneurol.2014.02.016.
9. Covington H.E., Maze I., Sun H., Bomze H.M., DeMaio K.D., Wu E.Y., Dietz D.M., Lobo M.K., Ghose S., Mouzon E., Neve R.L., Tamminga C.A., Nestler E.J. A role for repressive histone methylation in cocaine-induced vulnerability to stress. Neuron 2011, 71(4):656-670.
10. Dietz D.M., Laplant Q., Watts E.L., Hodes G.E., Russo S.J., Feng J., Oosting R.S., Vialou V., Nestler E.J. Paternal transmission of stress-induced pathologies. Biol. Psychiatry 2011, 70(5):408-414.
11. Djamshidian A., Friedman J.H. Anxiety and depression in Parkinson's disease. Curr. Treat. Options Neurol. 2014, 16(4):285.
12. Donahue R.J., Muschamp J.W., Russo S.J., Nestler E.J., Carlezon W.A. Effects of striatal DeltaFosB overexpression and ketamine on social defeat stress-induced anhedonia in mice. Biol. Psychiatry 2014, 16(4):285. 10.1016/j.biopsych.2013.12.014.
13. Duclot F., Kabbaj M. Individual differences in novelty seeking predict subsequent vulnerability to social defeat through a differential epigenetic regulation of brain-derived neurotrophic factor expression. J. Neurosci. 2013, 33(27):11048-11060.
14. Duman R.S., Monteggia L.M. A neurotrophic model for stress-related mood disorders. Biol. Psychiatry 2006, 59(12):1116-1127.
15. Espallergues J., Teegarden S.L., Veerakumar A., Boulden J., Challis C., Jochems J., Chan M., Petersen T., Deneris E., Matthias P., Hahn C.G., Lucki I., Beck S.G., Berton O. HDAC6 regulates glucocorticoid receptor signaling in serotonin pathways with critical impact on stress resilience. J. Neurosci. 2012, 32(13):4400-4416.
16. Friedman A.K., Walsh J.J., Juarez B., Ku S.M., Chaudhury D., Wang J., Li X., Dietz D.M., Pan N., Vialou V.F., Neve R.L., Yue Z., Han M.H. Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience. Science 2014, 344(6181):313-319.
17. Golden S.A., Covington H.E., Berton O., Russo S.J. A standardized protocol for repeated social defeat stress in mice. Nat. Protoc. 2011, 6(8):1183-1191.
18. Graham D.L., Krishnan V., Larson E.B., Graham A., Edwards S., Bachtell R.K., Simmons D., Gent L.M., Berton O., Bolanos C.A., DiLeone R.J., Parada L.F., Nestler E.J., Self D.W. Tropomyosin-related kinase B in the mesolimbic dopamine system: region-specific effects on cocaine reward. Biol. Psychiatry 2009, 65(8):696-701.
19. Greenberg G.D., Laman-Maharg A., Campi K.L., Voigt H., Orr V.N., Schaal L., Trainor B.C. Sex differences in stress-induced social withdrawal: role of brain derived neurotrophic factor in the bed nucleus of the stria terminalis. Front. Behav. Neurosci. 2014, 7:223.
20. Hellmann-Regen J., Piber D., Hinkelmann K., Gold S.M., Heesen C., Spitzer C., Endres M., Otte C. Depressive syndromes in neurological disorders. Eur. Arch. Psychiatry Clin. Neurosci. 2013, 263(Suppl. 2):S123-S136.
21. Kanner A.M., Schachter S.C., Barry J.J., Hersdorffer D.C., Mula M., Trimble M., Hermann B., Ettinger A.E., Dunn D., Caplan R., Ryvlin P., Gilliam F. Depression and epilepsy: epidemiologic and neurobiologic perspectives that may explain their high comorbid occurrence. Epilepsy Behav. 2012, 24(2):156-168.
22. Krishnan V., Nestler E.J. Animal models of depression: molecular perspectives. Curr. Top. Behav. Neurosci. 2011, 7:121-147.
23. Krishnan V., Han M.H., Graham D.L., Berton O., Renthal W., Russo S.J., Laplant Q., Graham A., Lutter M., Lagace D.C., Ghose S., Reister R., Tannous P., Green T.A., Neve R.L., Chakravarty S., Kumar A., Eisch A.J., Self D.W., Lee F.S., Tamminga C.A., Cooper D.C., Gershenfeld H.K., Nestler E.J. Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell 2007, 131(2):391-404.
24. Krishnan V., Han M.H., Mazei-Robison M., Iniguez S.D., Ables J.L., Vialou V., Berton O., Ghose S., Covington H.E., Wiley M.D., Henderson R.P., Neve R.L., Eisch A.J., Tamminga C.A., Russo S.J., Bolanos C.A., Nestler E.J. AKT signaling within the ventral tegmental area regulates cellular and behavioral responses to stressful stimuli. Biol. Psychiatry 2008, 64(8):691-700.
25. Kudryavtseva N.N., Bakshtanovskaya I.V., Koryakina L.A. Social model of depression in mice of C57BL/6J strain. Pharmacol. Biochem. Behav. 1991, 38(2):315-320.
26. Lagace D.C., Donovan M.H., DeCarolis N.A., Farnbauch L.A., Malhotra S., Berton O., Nestler E.J., Krishnan V., Eisch A.J. Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance. Proc. Natl. Acad. Sci. U. S. A. 2010, 107(9):4436-4441.
27. LaPlant Q., Vialou V., Covington H.E., Dumitriu D., Feng J., Warren B.L., Maze I., Dietz D.M., Watts E.L., Iniguez S.D., Koo J.W., Mouzon E., Renthal W., Hollis F., Wang H., Noonan M.A., Ren Y., Eisch A.J., Bolanos C.A., Kabbaj M., Xiao G., Neve R.L., Hurd Y.L., Oosting R.S., Fan G., Morrison J.H., Nestler E.J. Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nat. Neurosci. 2010, 13(9):1137-1143.
28. Mahan A.L., Ressler K.J. Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder. Trends Neurosci. 2012, 35(1):24-35.
29. Renthal W., Maze I., Krishnan V., Covington H.E., Xiao G., Kumar A., Russo S.J., Graham A., Tsankova N., Kippin T.E., Kerstetter K.A., Neve R.L., Haggarty S.J., McKinsey T.A., Bassel-Duby R., Olson E.N., Nestler E.J. Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. Neuron 2007, 56(3):517-529.
30. Russo S.J., Murrough J.W., Han M.H., Charney D.S., Nestler E.J. Neurobiology of resilience. Nat. Neurosci. 2012, 15(11):1475-1484.
31. Rutter M. Implications of resilience concepts for scientific understanding. Ann. N. Y. Acad. Sci. 2006, 1094:1-12.
32. Santiago P.N., Ursano R.J., Gray C.L., Pynoos R.S., Spiegel D., Lewis-Fernandez R., Friedman M.J., Fullerton C.S. A systematic review of PTSD prevalence and trajectories in DSM-5 defined trauma exposed populations: intentional and non-intentional traumatic events. PLoS One 2013, 8(4):e59236.
33. Schmidt H.D., Duman R.S. Peripheral BDNF produces antidepressant-like effects in cellular and behavioral models. Neuropsychopharmacology 2010, 35(12):2378-2391.
34. Sexton C.E., Mackay C.E., Ebmeier K.P. A systematic review and meta-analysis of magnetic resonance imaging studies in late-life depression. Am. J. Geriatr. Psychiatry 2013, 21(2):184-195.
35. Smith M.A., Makino S., Kvetnansky R., Post R.M. Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. J. Neurosci. 1995, 15(3 Pt 1):1768-1777.
36. Strekalova T., Spanagel R., Bartsch D., Henn F.A., Gass P. Stress-induced anhedonia in mice is associated with deficits in forced swimming and exploration. Neuropsychopharmacology 2004, 29(11):2007-2017.
37. Taylor S.L., Stanek L.M., Ressler K.J., Huhman K.L. Differential brain-derived neurotrophic factor expression in limbic brain regions following social defeat or territorial aggression. Behav. Neurosci. 2011, 125(6):911-920.
38. Tsankova N.M., Berton O., Renthal W., Kumar A., Neve R.L., Nestler E.J. Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat. Neurosci. 2006, 9(4):519-525.
39. Tse Y.C., Montoya I., Wong A.S., Mathieu A., Lissemore J., Lagace D.C., Wong T.P. A longitudinal study of stress-induced hippocampal volume changes in mice that are susceptible or resilient to chronic social defeat. Hippocampus 2014, 10.1002/hipo.22296.
40. Vialou V., Robison A.J., Laplant Q.C., Covington H.E., Dietz D.M., Ohnishi Y.N., Mouzon E., Rush A.J., Watts E.L., Wallace D.L., Iniguez S.D., Ohnishi Y.H., Steiner M.A., Warren B.L., Krishnan V., Bolanos C.A., Neve R.L., Ghose S., Berton O., Tamminga C.A., Nestler E.J. DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses. Nat. Neurosci. 2010, 13(6):745-752.
41. Wang J., Fanous S., Terwilliger E.F., Bass C.E., Hammer R.P., Nikulina E.M. BDNF overexpression in the ventral tegmental area prolongs social defeat stress-induced cross-sensitization to amphetamine and increases DeltaFosB expression in mesocorticolimbic regions of rats. Neuropsychopharmacology 2013, 38(11):2286-2296.
42. Wilkinson M.B., Xiao G., Kumar A., LaPlant Q., Renthal W., Sikder D., Kodadek T.J., Nestler E.J. Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models. The Journal of neuroscience: the official journal of the Society for Neuroscience 2009, 29(24):7820-7832.