The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis

Molecular Psychiatry

Volumn 20, Issue 4, 2015, Pages 500-508

  Walker, A K ^a,b   Rivera, P D ^b   Wang, Q ^a,b   Chuang, J C ^a,b   Tran, S ^a   Osborne Lawrence, S ^a,b   Estill, S J ^a   Starwalt, R ^a   Huntington, P ^a   Morlock, L ^a   Naidoo, J ^a   Williams, N S ^a   Ready, J M ^a   Eisch, A J ^b   Pieper, A A ^c   Zigman, J M ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; ANTIDEPRESSANT AGENT; CITALOPRAM; CLOMIPRAMINE; DESIPRAMINE; FLUOXETINE; GHRELIN RECEPTOR; IMIPRAMINE; MIRTAZAPINE; NEUROPROTECTIVE AGENT; NORTRIPTYLINE; P 7C 3 NEUROPROTECTIVE AGENT; P 7C3 A20 NEUROPROTECTIVE AGENT; PAROXETINE; PHENELZINE; SERTRALINE; TRANYLCYPROMINE; UNCLASSIFIED DRUG; VENLAFAXINE; CARBAZOLE DERIVATIVE; ENOLASE; KI 67 ANTIGEN; P7C3 COMPOUND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN REGION; BRAIN TISSUE; CALORIC RESTRICTION; CELL DEATH; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC SOCIAL DEFEAT STRESS; CHRONIC STRESS; CONTROLLED STUDY; DENTATE GYRUS; DEPRESSION; DISEASE SEVERITY; DRUG EFFICACY; HIPPOCAMPAL NEUROGENESIS; HIPPOCAMPAL STEM CELL; MAJOR DEPRESSION; MEMORY; MENTAL STRESS; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIATION; SOCIAL AVOIDANCE BEHAVIOR; SOCIAL DOMINANCE; SPATIAL LEARNING; STEM CELL; SUBGRANULAR ZONE; WILD TYPE; ANIMAL; BEHAVIOR; C57BL MOUSE; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; DRUG THERAPY; GENETICS; HIPPOCAMPUS; MALE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PSYCHOLOGY; RADIATION RESPONSE; SKULL IRRADIATION; SWIMMING; TIME;

ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIORAL SYMPTOMS; CALORIC RESTRICTION; CARBAZOLES; CELL PROLIFERATION; CRANIAL IRRADIATION; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; KI-67 ANTIGEN; MALE; MICE; MICE, INBRED C57BL; NEUROGENESIS; NEURONS; NEUROPROTECTIVE AGENTS; PHOSPHOPYRUVATE HYDRATASE; RECEPTORS, GHRELIN; SWIMMING; TIME FACTORS;

EID: 84926158983     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2014.34     Document Type: Article

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