Antidepressant medication as a risk factor for type 2 diabetes and impaired glucose regulation

Diabetes Care

Volumn 36, Issue 10, 2013, Pages 3337-3345

  Barnard, Katharine ^a   Peveler, Robert C ^a   Holt, Richard I G ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; AMITRIPTYLINE; AMOXAPINE; ANTIDEPRESSANT AGENT; BENZODIAZEPINE; CLOMIPRAMINE; DESIPRAMINE; DOPAMINE UPTAKE INHIBITOR; DOSULEPIN; DULOXETINE; FLUOXETINE; FLUVOXAMINE; IMIPRAMINE; IPRONIAZID; ISOCARBOXAZID; MAPROTILINE; MIANSERIN; MIRTAZAPINE; MONOAMINE OXIDASE INHIBITOR; NORTRIPTYLINE; PAROXETINE; PHENELZINE; PLACEBO; SEROTONERGIC ANTIDEPRESSANT; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG; VENLAFAXINE;

ANTIDIABETIC ACTIVITY; BLOOD GLUCOSE MONITORING; CASE STUDY; COCHRANE LIBRARY; COHORT ANALYSIS; CROSS-SECTIONAL STUDY; DEPRESSION; DISEASE ASSOCIATION; DISORDERS OF CARBOHYDRATE METABOLISM; DRUG USE; DRUG WITHDRAWAL; EMBASE; GLUCOSE BLOOD LEVEL; HUMAN; HYPERGLYCEMIA; HYPOGLYCEMIA; IMPAIRED GLUCOSE REGULATION; INCIDENCE; INFORMATION RETRIEVAL; MEDLINE; METHODOLOGY; NON INSULIN DEPENDENT DIABETES MELLITUS; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PSYCINFO; PUBLICATION; REVIEW; RISK ASSESSMENT; RISK FACTOR; SYSTEMATIC REVIEW;

ANTIDEPRESSIVE AGENTS; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; HUMANS; RISK FACTORS;

EID: 84891883011     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc13-0560     Document Type: Review

References (34)

1. National Health Executive. Available from: http://www. nationalhealthexecutive.com/Health-Care-News/antidepressant. Accessed 5 February 2013
2. Serretti A, Mandelli L. Antidepressants and body weight: a comprehensive review and meta-analysis. J Clin Psychiatry 2010; 71:1259-1272
3. Isotani H, Kameoka K. Hypoglycemia associated with maprotiline in a patientwith type 1 diabetes. Diabetes Care 1999;22:862-863
4. Sansone RA, Sansone LA. Driving on antidepressants: cruising for a crash? Psychiatry (Edgmont) 2009;6:13-16
5. Khoza S, Barner JC. Glucose dysregulation associated with antidepressant agents: an analysis of 17 published case reports. Int J Clin Pharmacol 2011;33:484-492
6. Erenmemisoglu A, Ozdogan UK, Saraymen R, Tutus A. Effect of some antidepressants on glycaemia and insulin levels of normoglycaemic and alloxan-induced hyperglycaemic mice. J Pharm Pharmacol 1999; 51:741-743
7. Barnard KD, Skinner TC, Peveler R. The The prevalence of co-morbid depression in adults with Type 1 diabetes: systematic literature review. Diabet Med 2006;23: 445-448
8. Centre for Reviews and Dissemination. Systematic Reviews: CRD's Guidance for Undertaking Reviews in Health Care. York, University of York, 2009
9. Crombie I. The Pocket Guide to Critical Appraisal. London, BMJ Publishing Group, 1996
10. Petticrew M, Roberts H. Systematic Reviews in the Social Sciences: A Practical Guide. Oxford, Blackwell, 2006
11. Sheldon TA. Making evidence synthesis more useful for management and policymaking. J Health Serv Res Policy 2005;10 (Suppl. 1):1-5
12. Pyykkönen AJ, Räikkönen K, Tuomi T, Eriksson JG,Groop L, Isomaa B. Depressive symptoms, antidepressant medication use, and insulin resistance: the PPP-Botnia Study. Diabetes Care 2011;34:2545-2547
13. Pyykkönen AJ, Räikkönen K, Tuomi T, Eriksson JG, Groop L, Isomaa B. Association between depressive symptoms and metabolic syndrome is not explained by antidepressant medication: results from the PPP-Botnia Study. Ann Med 2012;44: 279-288
14. Raeder MB, Bjelland I, Emil Vollset S, Steen VM. Obesity, dyslipidemia, and diabetes with selective serotonin reuptake inhibitors: the Hordaland Health Study. J Clin Psychiatry 2006;67:1974-1982
15. Mezuk B, Johnson-Lawrence V, Lee H, et al. Is ignorance bliss? Depression, antidepressants, and the diagnosis of prediabetes and type 2 diabetes. Health Psychol 2013; 32:254-263
16. Andersohn F, Schade R, Suissa S, Garbe E. Long-term use of antidepressants for depressive disorders and the risk of diabetes mellitus. Am J Psychiatry 2009;166:591-598
17. Knol MJ, Geerlings MI, Grobbee DE, Egberts AC, Heerdink ER. Antidepressant use before and after initiation of diabetes mellitus treatment. Diabetologia 2009;52: 425-432
18. Kivimäki M, Hamer M, Batty GD, et al. Antidepressant medication use, weight gain, and risk of type 2 diabetes: a populationbased study. Diabetes Care 2010;33:2611-2616
19. Kivimäki M, Tabak AG, Lawlor DA, et al. Antidepressant use before and after the diagnosis of type 2 diabetes: a longitudinal modeling study. Diabetes Care 2010;33: 1471-1476
20. Brown LC, Majumdar SR, Johnson JA. Type of antidepressant therapy and risk of type 2 diabetes in people with depression. Diabetes Res Clin Pract 2008;79:61-67
21. Rubin RR, Ma Y, Marrero DG, et al.;Diabetes Prevention Program Research Group. Elevated depression symptoms, antidepressant medicine use, and risk of developing diabetes during the diabetes prevention program. Diabetes Care 2008;31:420-426
22. Rubin RR, Ma Y, Peyrot M, et al.; Diabetes Prevention Program Research Group. Antidepressant medicine use and risk of developing diabetes during the diabetes prevention program and diabetes prevention program outcomes study. Diabetes Care 2010;33:2549-2551
23. Atlantis E, Browning C, Sims J, Kendig H. Diabetes incidence associated with depression and antidepressants in the Melbourne Longitudinal Studies on Healthy Ageing (MELSHA). Int J Geriatr Psychiatry 2010;25:688-696
24. Campayo A, de Jonge P, Roy JF, et al.; ZARADEMP Project. Depressive disorder and incident diabetes mellitus: the effect of characteristics of depression. Am J Psychiatry 2010;167:580-588
25. Ma Y, Balasubramanian R, Pagoto SL, et al. Elevated depressive symptoms, antidepressant use, and diabetes in a large multiethnic national sample of postmenopausal women. Diabetes Care 2011;34:2390-2392
26. Pan A, Sun Q, Okereke OI, et al. Use of antidepressant medication and risk of type 2 diabetes: results from three cohorts of US adults. Diabetologia 2012;55:63-72
27. Khoza S, Barner JC, Bohman TM, Rascati K, Lawson K, Wilson JP. Use of antidepressant agents and the risk of type 2 diabetes. Eur J Clin Pharmacol 2012;68:1295-1302
28. Kivimäki M, Batty GD, Jokela M, et al. Antidepressant medication use and risk of hyperglycemia and diabetes mellitus: a noncausal association? Biol Psychiatry 2011;70:978-984
29. Knol MJ, Geerlings MI, Egberts AC, Gorter KJ, Grobbee DE, Heerdink ER. No increased incidence of diabetes in antidepressant users. Int Clin Psychopharmacol 2007;22:382-386
30. Hennings JM, Schaaf L, Fulda S. Glucose metabolism and antidepressant medication. Curr Pharm Des 2012;18:5900-5919
31. McIntyre RS, Soczynska JK, Konarski JZ, Kennedy SH. The effect of antidepressants on glucose homeostasis and insulin sensitivity: synthesis and mechanisms. Expert Opin Drug Saf 2006;5:157-168
32. Crucitti A, Zhang Q, Nilsson M, Brecht S, Yang CR, Wernicke J. Duloxetine treatment and glycemic controls in patients with diagnoses other than diabetic peripheral neuropathic pain: a meta-analysis. Curr Med Res Opin 2010;26:2579-2588
33. Holt RI, Peveler RC. Association between antipsychotic drugs and diabetes. Diabetes Obes Metab 2006;8:125-135
34. Bradford Hill A. The environment and disease: association or causation? Proc R Soc Med 1965;58:295-300