The redox state of the alarmin HMGB1 is a pivotal factor in neuroinflammatory and microglial priming: A role for the NLRP3 inflammasome

Brain, Behavior, and Immunity

Volumn 55, Issue , 2016, Pages 215-224

  Frank, Matthew G ^a   Weber, Michael D ^a   Fonken, Laura K ^a   Hershman, Sarah A ^a   Watkins, Linda R ^a   Maier, Steven F ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

HMGB1; Microglia; Neuroinflammation; Priming; Redox state

Indexed keywords

CRYOPYRIN; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; ALARMIN; AUTACOID; HBP1 PROTEIN, RAT; INFLAMMASOME; NLRP3 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CISTERNA MAGNA; GENE; GENE EXPRESSION; HIPPOCAMPUS; IMMUNOPHENOTYPING; MALE; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OXIDATION REDUCTION STATE; PATHOGENESIS; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; RAT; TNFALPHA GENE; ANIMAL; IMMUNOLOGY; INFLAMMATION; OXIDATION REDUCTION REACTION; SPRAGUE DAWLEY RAT;

ALARMINS; ANIMALS; HIPPOCAMPUS; HMGB1 PROTEIN; INFLAMMASOMES; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; MICROGLIA; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; OXIDATION-REDUCTION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84948695894     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2015.10.009     Document Type: Article

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