Kososan, but not milnacipran, elicits antidepressant-like effects in a novel psychological stress-induced mouse model of depression

Traditional and Kampo Medicine

Volumn 2, Issue 1, 2015, Pages 1-7

  Hori, Atsushi ^a   Ito, Naoki ^b   Oikawa, Tetsuro ^b   Hanawa, Toshihiko ^a,b  

^a KITASATO UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b KITASATO UNIVERSITY   (Japan)

Author keywords

antidepressant like effect; depression like model; forced swimming test; Kampo; kososan; milnacipran

Indexed keywords

BROXURIDINE; CORTICOSTERONE; KAMPO; KOSOSAN; MILNACIPRAN; OREXIN A; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; ARTICLE; BRDU ASSAY; CHINESE MEDICINE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DENTATE GYRUS; DEPRESSION; DRUG EFFECT; FLUID INTAKE; FOOD INTAKE; FORCED SWIM TEST; HYPOTHALAMUS; IMMOBILITY; IMMUNOHISTOCHEMISTRY; LOCOMOTION; MALE; MENTAL STRESS; MOUSE; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; RAT; WEIGHT GAIN;

EID: 84964363089     PISSN: None     EISSN: 20534515     Source Type: Journal    
DOI: 10.1002/tkm2.1013     Document Type: Article

References (28)

1. Andrade L, Caraveo-Anduaga JJ, Berglund P et al. The epidemiology of major depressive episodes: results from the International Consortium of Psychiatric Epidemiology (ICPE) Surveys. Int. J. Methods Psychiatr. Res. 2003; 12: 3–21.
2. Pryce CR, Azzinnari D, Spinelli S, Seifritz E, Tegethoff M, Meinlschmidt G. Helplessness: a systematic translational review of theory and evidence for its relevance to understanding and treating depression. Pharmacol. Ther. 2011; 132: 242–267.
3. Kessler RC. The effects of stressful life events on depression. Annu. Rev. Psychol. 1997; 48: 191–214.
4. Kendler KS. Long-term care of an individual with schizophrenia: pharmacologic, psychological, and social factors. Am. J. Psychiatry 1999; 156: 124–128.
5. Caspi A, Sugden K, Moffitt TE et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003; 301: 386–389.
6. Kessing LV, Bukh JD. Genetics and stressful life events interact in depression. Ugeskr. Laeger 2013; 175: 948–951.
7. Nestler EJ, Hyman SE. Animal models of neuropsychiatric disorders. Nat. Neurosci. 2010; 13: 1161–1169.
8. Kvetnansky R, Pacak K, Fukuhara K et al. Sympathoadrenal system in stress. Interaction with the hypothalamic-pituitary-adrenocortical system. Ann. N. Y. Acad. Sci. 1995; 771: 131–158.
9. Bunney WE Jr, Davis JM. Norepinephrine in depressive reactions. A review. Arch. Gen. Psychiatry 1965; 13: 483–494.
10. Ilyas S, Moncrieff J. Trends in prescriptions and costs of drugs for mental disorders in England, 1998–2010. Br. J. Psychiatry 2012; 200: 393–398.
11. Shah A, Carreno FR, Frazer A. Therapeutic modalities for treatment resistant depression: focus on vagal nerve stimulation and ketamine. Clin. Psychopharmacol. Neurosci. 2014; 12: 83–93.
12. Fournier JC, DeRubeis RJ, Hollon SD et al. Antidepressant drug effects and depression severity: a patient-level meta-analysis. JAMA 2010; 303: 47–53.
13. Ito N, Nagai T, Oikawa T, Yamada H, Hanawa T. Antidepressant-like effect of l-perillaldehyde in stress-induced depression-like model mice through regulation of the olfactory nervous system. Evid. Based Complement. Alternat. Med. 2011; 2011: 512697.
14. Krishnan V, Nestler EJ. The molecular neurobiology of depression. Nature 2008; 455: 894–902.
15. Willner P. Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation. Psychopharmacology (Berl) 1997; 134: 319–329.
16. Petit-Demouliere B, Chenu F, Bourin M. Forced swimming test in mice: a review of antidepressant activity. Psychopharmacology (Berl) 2005; 177: 245–255.
17. Ito N, Hori A, Yabe T et al. Involvement of neuropeptide Y signaling in the antidepressant-like effect and hippocampal cell proliferation induced by kososan, a Kampo medicine, in the stress-induced depression-like model mice. Biol. Pharm. Bull. 2012; 35: 1775–1783.
18. Ito N, Yabe T, Nagai T, Oikawa T, Yamada H, Hanawa T. A possible mechanism underlying an antidepressive-like effect of Kososan, a Kampo medicine, via the hypothalamic orexinergic system in the stress-induced depression-like model mice. Biol. Pharm. Bull. 2009; 32: 1716–1722.
19. Porsolt RD, Bertin A, Jalfre M. Behavioral despair in mice: a primary screening test for antidepressants. Arch. Int. Pharmacodyn. Ther. 1977; 229: 327–336.
20. Bartolomucci A, Palanza P, Sacerdote P et al. Individual housing induces altered immuno-endocrine responses to psychological stress in male mice. Psychoneuroendocrinology 2003; 28: 540–558.
21. Ito N, Yabe T, Gamo Y et al. I.c.v. administration of orexin-A induces an antidepressive-like effect through hippocampal cell proliferation. Neuroscience 2008; 157: 720–732.
22. Palhagen S, Qi H, Martensson B, Walinder J, Granerus AK, Svenningsson P. Monoamines, BDNF, IL-6 and corticosterone in CSF in patients with Parkinson's disease and major depression. J. Neurol. 2010; 257: 524–532.
23. Steiner MA, Marsicano G, Wotjak CT, Lutz B. Conditional cannabinoid receptor type 1 mutants reveal neuron subpopulation-specific effects on behavioral and neuroendocrine stress responses. Psychoneuroendocrinology 2008; 33: 1165–1170.
24. Warren BL, Vialou VF, Iniguez SD et al. Neurobiological sequelae of witnessing stressful events in adult mice. Biol. Psychiatry 2013; 73: 7–14.
25. Papciak J, Popik P, Fuchs E, Rygula R. Chronic psychosocial stress makes rats more ‘pessimistic’ in the ambiguous-cue interpretation paradigm. Behav. Brain Res. 2013; 256: 305–310.
26. Golden SA, Covington HE III, Berton O, Russo SJ. A standardized protocol for repeated social defeat stress in mice. Nat. Protoc. 2011; 6: 1183–1191.
27. Hanawa T. Kososan and Hangekobokuto. J. Kampo Med. 1995; 42: 418–426.
28. Jeong JY, Lee DH, Kang SS. Effects of chronic restraint stress on body weight, food intake, and hypothalamic gene expressions in mice. Endocrinol. Metab. (Seoul) 2013; 28: 288–296.