Imipramine attenuates neuroinflammatory signaling and reverses stress-induced social avoidance

Brain, Behavior, and Immunity

Volumn 46, Issue , 2015, Pages 212-220

  Ramirez, Karol ^a,c   Shea, Daniel T ^b   McKim, Daniel B ^a,b   Reader, Brenda F ^b   Sheridan, John F ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^c UNIVERSIDAD DE COSTA RICA   (Costa Rica)

Author keywords

Imipramine; Microglia; Psychosocial stress; Social avoidance; Social defeat

Indexed keywords

DRINKING WATER; IMIPRAMINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; TRICYCLIC ANTIDEPRESSANT AGENT; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE OVEREXPRESSION; MALE; MENTAL STRESS; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOCIAL AVOIDANCE BEHAVIOR; SOCIAL INTERACTION; SPLEEN CELL; STRESS INDUCED SOCIAL AVOIDANCE; ANIMAL; ANIMAL BEHAVIOR; BRAIN; C57BL MOUSE; DRUG EFFECTS; GENETICS; IMMUNOLOGY; METABOLISM; SOCIAL BEHAVIOR;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BEHAVIOR, ANIMAL; BRAIN; IMIPRAMINE; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED C57BL; MICROGLIA; SOCIAL BEHAVIOR; STRESS, PSYCHOLOGICAL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84928828181     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2015.01.016     Document Type: Article

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