Stress induces the danger-associated molecular pattern HMGB-1 in the hippocampus of male sprague dawley rats: A priming stimulus of microglia and the NLRP3 inflammasome

Journal of Neuroscience

Volumn 35, Issue 1, 2015, Pages 316-324

  Weber, Michael D ^a   Frank, Matthew G ^a   Tracey, Kevin J ^b   Watkins, Linda R ^a   Maier, Steven F ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

DAMPS; HMGB 1; Inflammasome; Microglia; Neuroinflammation; Stress

Indexed keywords

ADVANCED GLYCATION END PRODUCT; COMPLEMENTARY DNA; CRYOPYRIN; GENOMIC DNA; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; NUCLEOTIDE BINDING PROTEIN; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; CARRIER PROTEIN; CELL RECEPTOR; HBP1 PROTEIN, RAT; NOD-LIKE RECEPTOR 3, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CELL ISOLATION; CELL VIABILITY; CONTROLLED STUDY; DNA EXTRACTION; GENE EXPRESSION; HIPPOCAMPUS; IMMUNE RESPONSE; INNATE IMMUNITY; MALE; MENTAL STRESS; MICROGLIA; MTT ASSAY; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; QUANTITATIVE ASSAY; RAT; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; METABOLISM; PSYCHOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; CARRIER PROTEINS; HIPPOCAMPUS; HMGB1 PROTEIN; INFLAMMASOMES; MALE; MICROGLIA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STRESS, PSYCHOLOGICAL;

EID: 84920545132     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3561-14.2015     Document Type: Article

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