Prostaglandin E 2-mediated attenuation of mesocortical dopaminergic pathway is critical for susceptibility to repeated social defeat stress in mice

Journal of Neuroscience

Volumn 32, Issue 12, 2012, Pages 4319-4329

  Tanaka, Kohei ^a,e   Furuyashiki, Tomoyuki ^a,e   Kitaoka, Shiho ^a   Senzai, Yuta ^a   Imoto, Yuki ^b   Segi Nishida, Eri ^b   Deguchi, Yuichi ^a   Breyer, Richard M ^c   Breyer, Matthew D ^d   Narumiya, Shuh ^a,e  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d ELI LILLY AND COMPANY   (United States)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; CYCLOOXYGENASE 1; DOPAMINE; DOPAMINE 1 RECEPTOR; PROSTAGLANDIN E RECEPTOR 1; PROSTAGLANDIN E2; 3,4 DIHYDROXYPHENYLACETIC ACID; 4 (5 (4 CHLOROPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL)BENZENESULFONAMIDE; 4-(5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)BENZENESULFONAMIDE; 5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; ACTIN BINDING PROTEIN; AIF1 PROTEIN, MOUSE; BENZAZEPINE DERIVATIVE; CALCIUM BINDING PROTEIN; CORTICOSTERONE; CYCLOOXYGENASE 2; DOPAMINE RECEPTOR BLOCKING AGENT; HOMOVANILLIC ACID; MEMBRANE PROTEIN; OXIDOPAMINE; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN SYNTHASE INHIBITOR; PTGS1 PROTEIN, MOUSE; PYRAZOLE DERIVATIVE; SULFONAMIDE; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DOPAMINERGIC SYSTEM; IMMUNOFLUORESCENCE TEST; MALE; MAZE TEST; MENTAL STRESS; MICROGLIA; MOUSE; NONHUMAN; ONCOGENE C FOS; PREFRONTAL CORTEX; PRIORITY JOURNAL; SOCIAL AVOIDANCE BEHAVIOR; SOCIAL DEFEAT STRESS; SOCIAL INTERACTION; ANALYSIS OF VARIANCE; ANIMAL; BLOOD; C57BL MOUSE; DISEASE MODEL; DISEASE PREDISPOSITION; DRUG EFFECT; GENETICS; HUMAN RELATION; INJURY; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MOUSE MUTANT; NERVE TRACT; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SOCIAL DOMINANCE; TIME; VENTRAL TEGMENTUM;

3,4-DIHYDROXYPHENYLACETIC ACID; ANALYSIS OF VARIANCE; ANIMALS; BENZAZEPINES; CALCIUM-BINDING PROTEINS; CORTICOSTERONE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; DOMINANCE-SUBORDINATION; DOPAMINE; DOPAMINE ANTAGONISTS; HOMOVANILLIC ACID; INTERPERSONAL RELATIONS; MAZE LEARNING; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; NEURAL PATHWAYS; OXIDOPAMINE; PREFRONTAL CORTEX; PYRAZOLES; RECEPTORS, PROSTAGLANDIN E; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL; SULFONAMIDES; TIME FACTORS; TYROSINE 3-MONOOXYGENASE; VENTRAL TEGMENTAL AREA;

EID: 84858395409     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5952-11.2012     Document Type: Article

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