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Volumn 125, Issue 4, 2017, Pages 721-729

In vitro effects of lead on gene expression in neural stem cells and associations between up-regulated genes and cognitive scores in children

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 13; EPIDERMAL GROWTH FACTOR; HEME OXYGENASE 1; LEAD; NERVE GROWTH FACTOR; OSTEOPONTIN; PROTHROMBIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); THIOREDOXIN REDUCTASE 1; TRANSCRIPTION FACTOR NRF2; DANGEROUS GOODS; SPP1 PROTEIN, HUMAN;

EID: 85016773833     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/EHP265     Document Type: Article
Times cited : (36)

References (68)
  • 1
    • 84924868841 scopus 로고    scopus 로고
    • The effect of osteopontin and osteopontin-derived peptides on preterm brain injury
    • Albertsson AM, Zhang X, Leavenworth J, Bi D, Nair S, Qiao L, et al. 2014. The effect of osteopontin and osteopontin-derived peptides on preterm brain injury. J Neuroinflammation 11:197, doi: 10.1186/s12974-014-0197-0.
    • (2014) J Neuroinflammation , vol.11 , pp. 197
    • Albertsson, A.M.1    Zhang, X.2    Leavenworth, J.3    Bi, D.4    Nair, S.5    Qiao, L.6
  • 2
    • 0025125719 scopus 로고
    • Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead
    • Alkondon M, Costa AC, Radhakrishnan V, Aronstam RS, Albuquerque EX. 1990. Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead. FEBS Lett 261:124–130.
    • (1990) FEBS Lett , vol.261 , pp. 124-130
    • Alkondon, M.1    Costa, A.C.2    Radhakrishnan, V.3    Aronstam, R.S.4    Albuquerque, E.X.5
  • 5
    • 84879018645 scopus 로고    scopus 로고
    • Prenatal exposures to environmental chemicals and children’s neurodevelopment: An update
    • Bellinger DC. 2013. Prenatal exposures to environmental chemicals and children’s neurodevelopment: an update. Saf Health Work 4:1–11.
    • (2013) Saf Health Work , vol.4 , pp. 1-11
    • Bellinger, D.C.1
  • 6
    • 84962224369 scopus 로고    scopus 로고
    • Lead contamination in Flint—an abject failure to protect public health
    • Bellinger DC. 2016. Lead contamination in Flint—an abject failure to protect public health. N Engl J Med 374:1101–1103.
    • (2016) N Engl J Med , vol.374 , pp. 1101-1103
    • Bellinger, D.C.1
  • 7
    • 0023110134 scopus 로고
    • Longitudinal analyses of prenatal and postnatal lead exposure and early cognitive development
    • Bellinger D, Leviton A, Waternaux C, Needleman H, Rabinowitz M. 1987. Longitudinal analyses of prenatal and postnatal lead exposure and early cognitive development. N Engl J Med 316:1037–1043.
    • (1987) N Engl J Med , vol.316 , pp. 1037-1043
    • Bellinger, D.1    Leviton, A.2    Waternaux, C.3    Needleman, H.4    Rabinowitz, M.5
  • 8
    • 49249113004 scopus 로고    scopus 로고
    • Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells
    • Breier JM, Radio NM, Mundy WR, Shafer TJ. 2008. Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells. Toxicol Sci 105:119–133.
    • (2008) Toxicol Sci , vol.105 , pp. 119-133
    • Breier, J.M.1    Radio, N.M.2    Mundy, W.R.3    Shafer, T.J.4
  • 10
    • 84908249389 scopus 로고    scopus 로고
    • Osteopontin expression in acute immune response mediates hippocampal synaptogenesis and adaptive outcome following cortical brain injury
    • Chan JL, Reeves TM, Phillips LL. 2014. Osteopontin expression in acute immune response mediates hippocampal synaptogenesis and adaptive outcome following cortical brain injury. Exp Neurol 261:757–771.
    • (2014) Exp Neurol , vol.261 , pp. 757-771
    • Chan, J.L.1    Reeves, T.M.2    Phillips, L.L.3
  • 11
    • 69249235848 scopus 로고    scopus 로고
    • Osteopontin increases migration and MMP-9 up-regulation via αvβ3 integrin, FAK, ERK, and NF-κB-dependent pathway in human chondrosarcoma cells
    • Chen YJ, Wei YY, Chen HT, Fong YC, Hsu CJ, Tsai CH, et al. 2009. Osteopontin increases migration and MMP-9 up-regulation via αvβ3 integrin, FAK, ERK, and NF-κB-dependent pathway in human chondrosarcoma cells. J Cell Physiol 221:98–108.
    • (2009) J Cell Physiol , vol.221 , pp. 98-108
    • Chen, Y.J.1    Wei, Y.Y.2    Chen, H.T.3    Fong, Y.C.4    Hsu, C.J.5    Tsai, C.H.6
  • 13
    • 84867317004 scopus 로고    scopus 로고
    • Identification of novel NRF2-regulated genes by ChIP-Seq: Influence on retinoid X receptor alpha
    • Chorley BN, Campbell MR, Wang X, Karaca M, Sambandan D, Bangura F, et al. 2012. Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha. Nucleic Acids Res 40:7416–7429.
    • (2012) Nucleic Acids Res , vol.40 , pp. 7416-7429
    • Chorley, B.N.1    Campbell, M.R.2    Wang, X.3    Karaca, M.4    Sambandan, D.5    Bangura, F.6
  • 14
    • 0037163092 scopus 로고    scopus 로고
    • Identification of a variant antioxidant response element in the promoter of the human glutamate-cysteine ligase modifier subunit gene. Revision of the ARE consensus sequence
    • Erickson AM, Nevarea Z, Gipp JJ, Mulcahy RT. 2002. Identification of a variant antioxidant response element in the promoter of the human glutamate-cysteine ligase modifier subunit gene. Revision of the ARE consensus sequence. J Biol Chem 277:30730–30737.
    • (2002) J Biol Chem , vol.277 , pp. 30730-30737
    • Erickson, A.M.1    Nevarea, Z.2    Gipp, J.J.3    Mulcahy, R.T.4
  • 16
    • 67349264922 scopus 로고    scopus 로고
    • Osteopontin increases lung cancer cells migration via activation of the αvβ3 integrin/ FAK/Akt and NF-κB-dependent pathway
    • Fong YC, Liu SC, Huang CY, Li TM, Hsu SF, Kao ST, et al. 2009. Osteopontin increases lung cancer cells migration via activation of the αvβ3 integrin/ FAK/Akt and NF-κB-dependent pathway. Lung Cancer 64:263–270.
    • (2009) Lung Cancer , vol.64 , pp. 263-270
    • Fong, Y.C.1    Liu, S.C.2    Huang, C.Y.3    Li, T.M.4    Hsu, S.F.5    Kao, S.T.6
  • 17
    • 0023179180 scopus 로고
    • Influence of blood lead on the ability and attainment of children in Edinburgh
    • Fulton M, Raab G, Thomson G, Laxen D, Hunter R, Hepburn W. 1987. Influence of blood lead on the ability and attainment of children in Edinburgh. Lancet 1:1221–1226.
    • (1987) Lancet , vol.1 , pp. 1221-1226
    • Fulton, M.1    Raab, G.2    Thomson, G.3    Laxen, D.4    Hunter, R.5    Hepburn, W.6
  • 18
    • 26444562983 scopus 로고    scopus 로고
    • Chronic developmental lead exposure reduces neurogenesis in adult rat hippocampus but does not impair spatial learning
    • Gilbert ME, Kelly ME, Samsam TE, Goodman JH. 2005. Chronic developmental lead exposure reduces neurogenesis in adult rat hippocampus but does not impair spatial learning. Toxicol Sci 86:365–374.
    • (2005) Toxicol Sci , vol.86 , pp. 365-374
    • Gilbert, M.E.1    Kelly, M.E.2    Samsam, T.E.3    Goodman, J.H.4
  • 20
    • 43549118615 scopus 로고    scopus 로고
    • Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primates
    • Guilarte TR, Burton NC, Verina T, Prabhu VV, Becker KG, Syversen T, et al. 2008. Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primates. J Neurochem 105:1948–1959.
    • (2008) J Neurochem , vol.105 , pp. 1948-1959
    • Guilarte, T.R.1    Burton, N.C.2    Verina, T.3    Prabhu, V.V.4    Becker, K.G.5    Syversen, T.6
  • 21
    • 0026619470 scopus 로고
    • 3H]MK-801 binding to the NMDA receptor-gated ionophore: In vitro and in vivo studies
    • 3H]MK-801 binding to the NMDA receptor-gated ionophore: in vitro and in vivo studies. Neurosci Lett 148:27–30.
    • (1992) Neurosci Lett , vol.148 , pp. 27-30
    • Guilarte, T.R.1    Miceli, R.C.2
  • 24
    • 5044238958 scopus 로고    scopus 로고
    • Effects of lead exposure on proliferation and differentiation of neural stem cells derived from different regions of embryonic rat brain
    • Huang F, Schneider JS. 2004. Effects of lead exposure on proliferation and differentiation of neural stem cells derived from different regions of embryonic rat brain. Neurotoxicology 25:1001–1012.
    • (2004) Neurotoxicology , vol.25 , pp. 1001-1012
    • Huang, F.1    Schneider, J.S.2
  • 25
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project
    • International HapMap Consortium. 2003. The International HapMap Project. Nature 426:789–796.
    • (2003) Nature , vol.426 , pp. 789-796
  • 26
    • 59649092811 scopus 로고    scopus 로고
    • Trends in blood lead levels and blood lead testing among US children aged 1 to 5 years, 1988–2004
    • Jones RL, Homa DM, Meyer PA, Brody DJ, Caldwell KL, Pirkle JL, et al. 2009. Trends in blood lead levels and blood lead testing among US children aged 1 to 5 years, 1988–2004. Pediatrics 123:e376–e385.
    • (2009) Pediatrics , vol.123 , pp. e376-e385
    • Jones, R.L.1    Homa, D.M.2    Meyer, P.A.3    Brody, D.J.4    Caldwell, K.L.5    Pirkle, J.L.6
  • 27
    • 84862163735 scopus 로고    scopus 로고
    • Osteopontin increases the proliferation of neural progenitor cells
    • Kalluri HS, Dempsey RJ. 2012. Osteopontin increases the proliferation of neural progenitor cells. Int J Dev Neurosci 30:359–362.
    • (2012) Int J Dev Neurosci , vol.30 , pp. 359-362
    • Kalluri, H.S.1    Dempsey, R.J.2
  • 28
    • 33847050801 scopus 로고    scopus 로고
    • Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
    • Kensler TW, Wakabayashi N, Biswal S. 2007. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu Rev Pharmacol Toxicol 47:89–116.
    • (2007) Annu Rev Pharmacol Toxicol , vol.47 , pp. 89-116
    • Kensler, T.W.1    Wakabayashi, N.2    Biswal, S.3
  • 29
    • 79960076098 scopus 로고    scopus 로고
    • Effects of N-acetylcysteine on TEGDMA- and HEMA-induced suppression of osteogenic differentiation of human osteosarcoma MG63 cells
    • Kim NR, Lim BS, Park HC, Son KM, Yang HC. 2011. Effects of N-acetylcysteine on TEGDMA- and HEMA-induced suppression of osteogenic differentiation of human osteosarcoma MG63 cells. J Biomed Mater Res B Appl Biomater 98:300–307.
    • (2011) J Biomed Mater Res B Appl Biomater , vol.98 , pp. 300-307
    • Kim, N.R.1    Lim, B.S.2    Park, H.C.3    Son, K.M.4    Yang, H.C.5
  • 30
    • 84946484705 scopus 로고    scopus 로고
    • Irradiation inhibits the maturation and mineralization of osteoblasts via the activation of Nrf2/HO-1 pathway
    • Kook SH, Kim KA, Ji H, Lee D, Lee JC. 2015. Irradiation inhibits the maturation and mineralization of osteoblasts via the activation of Nrf2/HO-1 pathway. Mol Cell Biochem 410:255–266.
    • (2015) Mol Cell Biochem , vol.410 , pp. 255-266
    • Kook, S.H.1    Kim, K.A.2    Ji, H.3    Lee, D.4    Lee, J.C.5
  • 31
    • 29944438649 scopus 로고    scopus 로고
    • Transcriptional regulation of the NAD(P)H:quinone oxidoreductase 1 and glutathione S-transferase ya genes by mercury, lead, and copper
    • Korashy HM, El-Kadi AO. 2006. Transcriptional regulation of the NAD(P)H:quinone oxidoreductase 1 and glutathione S-transferase ya genes by mercury, lead, and copper. Drug Metab Dispos 34:152–165.
    • (2006) Drug Metab Dispos , vol.34 , pp. 152-165
    • Korashy, H.M.1    El-Kadi, A.O.2
  • 32
    • 0038146898 scopus 로고    scopus 로고
    • Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis
    • Lee JM, Calkins MJ, Chan K, Kan YW, Johnson JA. 2003. Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis. J Biol Chem 278:12029–12038.
    • (2003) J Biol Chem , vol.278 , pp. 12029-12038
    • Lee, J.M.1    Calkins, M.J.2    Chan, K.3    Kan, Y.W.4    Johnson, J.A.5
  • 33
    • 84964827619 scopus 로고    scopus 로고
    • Crumbling infrastructure and learning impairment: A call for responsibility [Editorial]
    • Levin ED. 2016. Crumbling infrastructure and learning impairment: a call for responsibility [Editorial]. Environ Health Perspect 124:A79, doi: 10.1289/EHP69.
    • (2016) Environ Health Perspect , vol.124 , pp. A79
    • Levin, E.D.1
  • 34
    • 30744434862 scopus 로고    scopus 로고
    • Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
    • Li J, Ji L. 2005. Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix. Heredity (Edinb) 95:221–227.
    • (2005) Heredity (Edinb) , vol.95 , pp. 221-227
    • Li, J.1    Ji, L.2
  • 35
    • 0037016759 scopus 로고    scopus 로고
    • Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells
    • Li J, Lee JM, Johnson JA. 2002. Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells. J Biol Chem 277:388–394.
    • (2002) J Biol Chem , vol.277 , pp. 388-394
    • Li, J.1    Lee, J.M.2    Johnson, J.A.3
  • 36
    • 84868022009 scopus 로고    scopus 로고
    • Osteopontin increases heme oxygenase-1 expression and subsequently induces cell migration and invasion in glioma cells
    • Lu DY, Yeh WL, Huang SM, Tang CH, Lin HY, Chou SJ. 2012. Osteopontin increases heme oxygenase-1 expression and subsequently induces cell migration and invasion in glioma cells. Neuro Oncol 14:1367–1378.
    • (2012) Neuro Oncol , vol.14 , pp. 1367-1378
    • Lu, D.Y.1    Yeh, W.L.2    Huang, S.M.3    Tang, C.H.4    Lin, H.Y.5    Chou, S.J.6
  • 37
    • 77957237159 scopus 로고    scopus 로고
    • Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis
    • Malhotra D, Portales-Casamar E, Singh A, Srivastava S, Arenillas D, Happel C, et al. 2010. Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis. Nucleic Acids Res 38:5718–5734.
    • (2010) Nucleic Acids Res , vol.38 , pp. 5718-5734
    • Malhotra, D.1    Portales-Casamar, E.2    Singh, A.3    Srivastava, S.4    Arenillas, D.5    Happel, C.6
  • 38
    • 80255127234 scopus 로고    scopus 로고
    • Cutadapt removes adapter sequences from high-throughput sequencing reads
    • Martin M. 2011. Cutadapt removes adapter sequences from high-throughput sequencing reads. EMBnet 17:10–12.
    • (2011) Embnet , vol.17 , pp. 10-12
    • Martin, M.1
  • 40
    • 77954360596 scopus 로고    scopus 로고
    • Lead exposure during synaptogenesis alters vesicular proteins and impairs vesicular release: Potential role of NMDA receptor-dependent BDNF signaling
    • Neal AP, Stansfield KH, Worley PF, Thompson RE, Guilarte TR. 2010. Lead exposure during synaptogenesis alters vesicular proteins and impairs vesicular release: potential role of NMDA receptor-dependent BDNF signaling. Toxicol Sci 116:249–263.
    • (2010) Toxicol Sci , vol.116 , pp. 249-263
    • Neal, A.P.1    Stansfield, K.H.2    Worley, P.F.3    Thompson, R.E.4    Guilarte, T.R.5
  • 41
    • 79952103671 scopus 로고    scopus 로고
    • Lead exposure during synaptogenesis alters NMDA receptor targeting via NMDA receptor inhibition
    • Neal AP, Worley PF, Guilarte TR. 2011. Lead exposure during synaptogenesis alters NMDA receptor targeting via NMDA receptor inhibition. Neurotoxicology 32:281–289.
    • (2011) Neurotoxicology , vol.32 , pp. 281-289
    • Neal, A.P.1    Worley, P.F.2    Guilarte, T.R.3
  • 42
    • 0018772514 scopus 로고
    • Deficits in psychologic and classroom performance of children with elevated dentine lead levels
    • Needleman HL, Gunnoe C, Leviton A, Reed R, Peresie H, Maher C, et al. 1979. Deficits in psychologic and classroom performance of children with elevated dentine lead levels. N Engl J Med 300:689–695.
    • (1979) N Engl J Med , vol.300 , pp. 689-695
    • Needleman, H.L.1    Gunnoe, C.2    Leviton, A.3    Reed, R.4    Peresie, H.5    Maher, C.6
  • 45
    • 58849100414 scopus 로고    scopus 로고
    • Prenatal exposure to lead, δ-aminolevulinic acid, and schizophrenia: Further evidence
    • Opler MG, Buka SL, Groeger J, McKeague I, Wei C, Factor-Litvak P, et al. 2008. Prenatal exposure to lead, δ-aminolevulinic acid, and schizophrenia: further evidence. Environ Health Perspect 116:1586–1590, doi: 10.1289/ehp.10464.
    • (2008) Environ Health Perspect , vol.116 , pp. 1586-1590
    • Opler, M.G.1    Buka, S.L.2    Groeger, J.3    McKeague, I.4    Wei, C.5    Factor-Litvak, P.6
  • 46
    • 79955843030 scopus 로고    scopus 로고
    • Global gene expression analysis reveals dynamic and developmental stage-dependent enrichment of lead-induced neurological gene alterations
    • Peterson SM, Zhang J, Weber G, Freeman JL. 2011. Global gene expression analysis reveals dynamic and developmental stage-dependent enrichment of lead-induced neurological gene alterations. Environ Health Perspect 119:615–621, doi: 10.1289/ehp.1002590.
    • (2011) Environ Health Perspect , vol.119 , pp. 615-621
    • Peterson, S.M.1    Zhang, J.2    Weber, G.3    Freeman, J.L.4
  • 47
    • 84942478280 scopus 로고
    • The decline in blood lead levels in the United States. The National Health and Nutrition Examination Surveys (NHANES)
    • Pirkle JL, Brody DJ, Gunter EW, Kramer RA, Paschal DC, Flegal KM, et al. 1994. The decline in blood lead levels in the United States. The National Health and Nutrition Examination Surveys (NHANES). JAMA 272:284–291.
    • (1994) JAMA , vol.272 , pp. 284-291
    • Pirkle, J.L.1    Brody, D.J.2    Gunter, E.W.3    Kramer, R.A.4    Paschal, D.C.5    Flegal, K.M.6
  • 48
  • 49
    • 84934986467 scopus 로고    scopus 로고
    • Osteopontin mediates survival, proliferation and migration of neural stem cells through the chemokine receptor CXCR4
    • Rabenstein M, Hucklenbroich J, Willuweit A, Ladwig A, Fink GR, Schroeter M, et al. 2015. Osteopontin mediates survival, proliferation and migration of neural stem cells through the chemokine receptor CXCR4. Stem Cell Res Ther 6:99, doi: 10.1186/s13287-015-0098-x.
    • (2015) Stem Cell Res Ther , vol.6 , pp. 99
    • Rabenstein, M.1    Hucklenbroich, J.2    Willuweit, A.3    Ladwig, A.4    Fink, G.R.5    Schroeter, M.6
  • 50
    • 77953176036 scopus 로고    scopus 로고
    • A scaling normalization method for differential expression analysis of RNA-seq data
    • Robinson MD, Oshlack A. 2010. A scaling normalization method for differential expression analysis of RNA-seq data. Genome Biol 11:R25, doi: 10.1186/gb-2010-11-3-r25.
    • (2010) Genome Biol , vol.11 , pp. R25
    • Robinson, M.D.1    Oshlack, A.2
  • 51
    • 84894120143 scopus 로고    scopus 로고
    • Lead induces similar gene expression changes in brains of gestationally exposed adult mice and in neurons differentiated from mouse embryonic stem cells
    • Sánchez-Martín FJ, Fan Y, Lindquist DM, Xia Y, Puga A. 2013. Lead induces similar gene expression changes in brains of gestationally exposed adult mice and in neurons differentiated from mouse embryonic stem cells. PloS One 8:e80558, doi: 10.1371/journal.pone.0080558.
    • (2013) Plos One , vol.8
    • Sánchez-Martín, F.J.1    Fan, Y.2    Lindquist, D.M.3    Xia, Y.4    Puga, A.5
  • 52
    • 84865705867 scopus 로고    scopus 로고
    • Effects of developmental lead exposure on the hippocampal transcriptome: Influences of sex, developmental period, and lead exposure level
    • Schneider JS, Anderson DW, Talsania K, Mettil W, Vadigepalli R. 2012. Effects of developmental lead exposure on the hippocampal transcriptome: influences of sex, developmental period, and lead exposure level. Toxicol Sci 129:108–125.
    • (2012) Toxicol Sci , vol.129 , pp. 108-125
    • Schneider, J.S.1    Anderson, D.W.2    Talsania, K.3    Mettil, W.4    Vadigepalli, R.5
  • 53
    • 7444239113 scopus 로고    scopus 로고
    • Inhibition of progenitor cell proliferation in the dentate gyrus of rats following post-weaning lead exposure
    • Schneider JS, Anderson DW, Wade TV, Smith MG, Leibrandt P, Zuck L, et al. 2005. Inhibition of progenitor cell proliferation in the dentate gyrus of rats following post-weaning lead exposure. Neurotoxicology 26:141–145.
    • (2005) Neurotoxicology , vol.26 , pp. 141-145
    • Schneider, J.S.1    Anderson, D.W.2    Wade, T.V.3    Smith, M.G.4    Leibrandt, P.5    Zuck, L.6
  • 54
    • 84899080543 scopus 로고    scopus 로고
    • Lead exposure disrupts global DNA methylation in human embryonic stem cells and alters their neuronal differentiation
    • Senut MC, Sen A, Cingolani P, Shaik A, Land SJ, Ruden DM. 2014. Lead exposure disrupts global DNA methylation in human embryonic stem cells and alters their neuronal differentiation. Toxicol Sci 139:142–161.
    • (2014) Toxicol Sci , vol.139 , pp. 142-161
    • Senut, M.C.1    Sen, A.2    Cingolani, P.3    Shaik, A.4    Land, S.J.5    Ruden, D.M.6
  • 58
    • 84883163288 scopus 로고    scopus 로고
    • Characterization of a novel long noncoding RNA, SCAL1, induced by cigarette smoke and elevated in lung cancer cell lines
    • Thai P, Statt S, Chen CH, Liang E, Campbell C, Wu R. 2013. Characterization of a novel long noncoding RNA, SCAL1, induced by cigarette smoke and elevated in lung cancer cell lines. Am J Respir Cell Mol Biol 49:204–211.
    • (2013) Am J Respir Cell Mol Biol , vol.49 , pp. 204-211
    • Thai, P.1    Statt, S.2    Chen, C.H.3    Liang, E.4    Campbell, C.5    Wu, R.6
  • 59
    • 84888305662 scopus 로고    scopus 로고
    • Nasal administration of recombi-nant osteopontin attenuates early brain injury after subarachnoid hemorrhage
    • Topkoru BC, Altay O, Duris K, Krafft PR, Yan J, Zhang JH. 2013. Nasal administration of recombi-nant osteopontin attenuates early brain injury after subarachnoid hemorrhage. Stroke 44:3189–3194.
    • (2013) Stroke , vol.44 , pp. 3189-3194
    • Topkoru, B.C.1    Altay, O.2    Duris, K.3    Krafft, P.R.4    Yan, J.5    Zhang, J.H.6
  • 60
    • 27544506060 scopus 로고    scopus 로고
    • Lead neurotoxicity: From exposure to molecular effects
    • Toscano CD, Guilarte TR. 2005. Lead neurotoxicity: from exposure to molecular effects. Brain Res Brain Res Rev 49:529–554.
    • (2005) Brain Res Brain Res Rev , vol.49 , pp. 529-554
    • Toscano, C.D.1    Guilarte, T.R.2
  • 61
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: Discovering splice junctions with RNA-Seq
    • Trapnell C, Pachter L, Salzberg SL. 2009. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25:1105–1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 62
    • 38349107037 scopus 로고    scopus 로고
    • Ethanol increases fetal human neurosphere size and alters adhesion molecule gene expression
    • Vangipuram SD, Grever WE, Parker GC, Lyman WD. 2008. Ethanol increases fetal human neurosphere size and alters adhesion molecule gene expression. Alcohol Clin Exp Res 32:339–347.
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 339-347
    • Vangipuram, S.D.1    Grever, W.E.2    Parker, G.C.3    Lyman, W.D.4
  • 63
    • 33947303852 scopus 로고    scopus 로고
    • Environmental lead exposure during early life alters granule cell neurogenesis and morphology in the hippocampus of young adult rats
    • Verina T, Rohde CA, Guilarte TR. 2007. Environmental lead exposure during early life alters granule cell neurogenesis and morphology in the hippocampus of young adult rats. Neuroscience 145:1037–1047.
    • (2007) Neuroscience , vol.145 , pp. 1037-1047
    • Verina, T.1    Rohde, C.A.2    Guilarte, T.R.3
  • 66
    • 42949123553 scopus 로고    scopus 로고
    • Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo
    • Yang L, Kemadjou JR, Zinsmeister C, Bauer M, Legradi J, Müller F, et al. 2007. Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo. Genome Biol 8:R227, doi: 10.1186/gb-2007-8-10-r227.
    • (2007) Genome Biol , vol.8 , pp. R227
    • Yang, L.1    Kemadjou, J.R.2    Zinsmeister, C.3    Bauer, M.4    Legradi, J.5    Müller, F.6
  • 67
    • 77955984131 scopus 로고    scopus 로고
    • Lead contributes to arterial intimal hyperplasia through nuclear factor erythroid 2-related factor-mediated endothelial interleukin 8 synthesis and subsequent invasion of smooth muscle cells
    • Zeller I, Knoflach M, Seubert A, Kreutmayer SB, Stelzmüller ME, Wallnoefer E, et al. 2010. Lead contributes to arterial intimal hyperplasia through nuclear factor erythroid 2-related factor-mediated endothelial interleukin 8 synthesis and subsequent invasion of smooth muscle cells. Arterioscler Thromb Vasc Biol 30:1733–1740.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 1733-1740
    • Zeller, I.1    Knoflach, M.2    Seubert, A.3    Kreutmayer, S.B.4    Stelzmüller, M.E.5    Wallnoefer, E.6
  • 68
    • 47849091540 scopus 로고    scopus 로고
    • Blood lead and cadmium levels and relevant factors among children from an e-waste recycling town in China
    • Zheng L, Wu K, Li Y, Qi Z, Han D, Zhang B, et al. 2008. Blood lead and cadmium levels and relevant factors among children from an e-waste recycling town in China. Environ Res 108:15–20.
    • (2008) Environ Res , vol.108 , pp. 15-20
    • Zheng, L.1    Wu, K.2    Li, Y.3    Qi, Z.4    Han, D.5    Zhang, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.