Osteopontin increases lung cancer cells migration via activation of the αvβ3 integrin/FAK/Akt and NF-κB-dependent pathway

Lung Cancer

Volumn 64, Issue 3, 2009, Pages 263-270

  Fong, Yi Chin ^a,b   Liu, Shan Chi ^a   Huang, Chun Yin ^c   Li, Te Mao ^a   Hsu, Sheng Feng ^a   Kao, Shung Te ^a   Tsai, Fuu Jen ^b   Chen, Wen Chi ^a   Chen, Chih Yi ^b   Tang, Chih Hsin ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY BEIGANG HOSPITAL   (Taiwan)

Author keywords

FAK; Integrin; Lung cancer; Migration; OPN

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; FOCAL ADHESION KINASE; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOPONTIN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; PYRROLIDINE DITHIOCARBAMATE; SERINE; SYNAPTOTAGMIN I; TOSYLPHENYLALANYL CHLOROMETHYL KETONE; VITRONECTIN RECEPTOR;

ARTICLE; CANCER CELL; CELL MIGRATION; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; MUTANT; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOCARCINOMA; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES; CELL LINE, TUMOR; CELL MOVEMENT; CHROMONES; FLAVONOIDS; FOCAL ADHESION KINASE 1; HUMANS; INTEGRIN ALPHAVBETA3; LUNG NEOPLASMS; MORPHOLINES; NF-KAPPA B; ONCOGENE PROTEIN V-AKT; OSTEOPONTIN; PHOSPHORYLATION; PROLINE; SIGNAL TRANSDUCTION; THIOCARBAMATES; TOSYLPHENYLALANYL CHLOROMETHYL KETONE;

EID: 67349264922     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2008.09.003     Document Type: Article

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