The effect of osteopontin and osteopontin-derived peptides on preterm brain injury

Journal of Neuroinflammation

Volumn 11, Issue 1, 2014, Pages

  Albertsson, Anna Maj ^a   Zhang, Xiaoli ^a,b   Leavenworth, Jianmei ^c,d   Bi, Dan ^a,b   Nair, Syam ^a   Qiao, Lili ^a,e   Hagberg, Henrik ^a,f   Mallard, Carina ^a   Cantor, Harvey ^c,d   Wang, Xiaoyang ^a,b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b ZHENGZHOU UNIVERSITY   (China)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e Shanghai Songjiang District Central Hospital   (China)

^f ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Brain injury; Hypoxia; Ischemia; Osteopontin; Preterm

Indexed keywords

ISOLEUCYLVALYLPROLYLTHREONYLVALYLASPARTYLVALYLPROLYLASPARAGINYLGLYCYLARGINYLGLYCYLASPARTYLSERYLLEUCYLALANYLTYROSYLGLYCYLLEUCYLARGININE; MESSENGER RNA; OSTEOPONTIN; PEPTIDE C154 198; PEPTIDE DERIVATIVE; RECOMBINANT OSTEOPONTIN; RECOMBINANT PROTEIN; THROMBIN CLEAVED OSTEOPONTIN; UNCLASSIFIED DRUG; PEPTIDE FRAGMENT;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; HYPOXIC ISCHEMIC ENCEPHALOPATHY; MOUSE; NEUROPROTECTION; NEWBORN; NONHUMAN; PREMATURITY; PROTEIN EXPRESSION; 129 MOUSE; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; BRAIN INJURIES; C57BL MOUSE; DOSE RESPONSE; FEMALE; GENETICS; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRANASAL DRUG ADMINISTRATION; KNOCKOUT MOUSE; MALE; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; TREATMENT OUTCOME;

ADMINISTRATION, INTRANASAL; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; BRAIN INJURIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; OSTEOPONTIN; PEPTIDE FRAGMENTS; TREATMENT OUTCOME;

EID: 84924868841     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-014-0197-0     Document Type: Article

References (65)

1. Back SA, Han BH, Luo NL, Chricton CA, Xanthoudakis S, Tam J, Arvin KL, Holtzman DM: Selective vulnerability of late oligodendrocyte progenitors to hypoxia-ischemia. J Neurosci 2002, 22:455-463.
2. Salmaso N, Jablonska B, Scafidi J, Vaccarino FM, Gallo V: Neurobiology of premature brain injury. Nat Neurosci 2014, 17:341-346.
3. Uede T: Osteopontin, intrinsic tissue regulator of intractable inflammatory diseases. Pathol Int 2011, 61:265-280.
4. Cantor H, Shinohara ML: Regulation of T-helper-cell lineage development by osteopontin: the inside story. Nat Rev Immunol 2009, 9:137-141.
5. Denhardt DT, Noda M, O'Regan AW, Pavlin D, Berman JS: Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival. J Clin Invest 2001, 107:1055-1061.
6. Doyle KP, Yang T, Lessov NS, Ciesielski TM, Stevens SL, Simon RP, King JS, Stenzel-Poore MP: Nasal administration of osteopontin peptide mimetics confers neuroprotection in stroke. J Cereb Blood Flow Metab 2008, 28:1235-1248.
7. Meller R, Stevens SL, Minami M, Cameron JA, King S, Rosenzweig H, Doyle K, Lessov NS, Simon RP, Stenzel-Poore MP: Neuroprotection by osteopontin in stroke. J Cereb Blood Flow Metab 2005, 25:217-225.
8. Hedtjärn M, Mallard C, Hagberg H: Inflammatory gene profiling in the developing mouse brain after hypoxia-ischemia. J Cereb Blood Flow Metab 2004, 24:1333-1351.
9. Tanaka F, Ozawa Y, Inage Y, Deguchi K, Itoh M, Imai Y, Kohsaka S, Takashima S: Association of osteopontin with ischemic axonal death in periventricular leukomalacia. Acta Neuropathol 2000, 100:69-74.
10. van Velthoven CT, Heijnen CJ, van Bel F, Kavelaars A: Osteopontin enhances endogenous repair after neonatal hypoxic-ischemic brain injury. Stroke 2011, 42:2294-2301.
11. Chen W, Ma Q, Suzuki H, Hartman R, Tang J, Zhang JH: Osteopontin reduced hypoxia-ischemia neonatal brain injury by suppression of apoptosis in a rat pup model. Stroke 2011, 42:764-769.
12. Back SA, Luo NL, Borenstein NS, Levine JM, Volpe JJ, Kinney HC: Late oligodendrocyte progenitors coincide with the developmental window of vulnerability for human perinatal white matter injury. J Neurosci 2001, 21:1302-1312.
13. Sun CM, Fiette L, Tanguy M, Leclerc C, Lo-Man R: Ontogeny and innate properties of neonatal dendritic cells. Blood 2003, 102:585-591.
14. Milner R, ffrench-Constant C: A developmental analysis of oligodendroglial integrins in primary cells: changes in αv-associated β subunits during differentiation. Development 1994, 120:3497-3506.
15. Rice JE 3rd, Vannucci RC, Brierley JB: The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann Neurol 1981, 9:131-141.
16. Sheldon RA, Sedik C, Ferriero DM: Strain-related brain injury in neonatal mice subjected to hypoxia-ischemia. Brain Res 1998, 810:114-122.
17. Albertsson AM, Bi D, Duan L, Zhang X, Leavenworth JW, Qiao L, Zhu C, Cardell S, Cantor H, Hagberg H, Mallard C, Wang X: The immune response after hypoxia-ischemia in a mouse model of preterm brain injury. J Neuroinflammation 2014, 11:153.
18. Danielyan L, Schäfer R, von Ameln-Mayerhofer A, Buadze M, Geisler J, Klopfer T, Burkhardt U, Proksch B, Verleysdonk S, Ayturan M, Buniatian GH, Gleiter CH, Frey WH 2nd: Intranasal delivery of cells to the brain. Eur J Cell Biol 2009, 88:315-324.
19. Wang X, Stridh L, Li W, Dean J, Elmgren A, Gan L, Eriksson K, Hagberg H, Mallard C: Lipopolysaccharide sensitizes neonatal hypoxic-ischemic brain injury in a MyD88-dependent manner. J Immunol 2009, 183:7471-7477.
20. Wang X, Hagberg H, Zhu C, Jacobsson B, Mallard C: Effects of intrauterine inflammation on the developing mouse brain. Brain Res 2007, 1144:180-185.
21. Shinohara ML, Kim HJ, Kim JH, Garcia VA, Cantor H: Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells. Proc Natl Acad Sci U S A 2008, 105:7235-7239.
22. Lin S, Fan LW, Rhodes PG, Cai Z: Intranasal administration of IGF-1 attenuates hypoxic-ischemic brain injury in neonatal rats. Exp Neurol 2009, 217:361-370.
23. van Velthoven CT, Kavelaars A, van Bel F, Heijnen CJ: Nasal administration of stem cells: a promising novel route to treat neonatal ischemic brain damage. Pediatr Res 2010, 68:419-422.
24. Wang X, Han W, Du X, Zhu C, Carlsson Y, Mallard C, Jacotot E, Hagberg H: Neuroprotective effect of Bax-inhibiting peptide on neonatal brain injury. Stroke 2010, 41:2050-2055.
25. Zhu C, Qiu L, Wang X, Hallin U, Candé C, Kroemer G, Hagberg H, Blomgren K: Involvement of apoptosis-inducing factor in neuronal death after hypoxia-ischemia in the neonatal rat brain. J Neurochem 2003, 86:306-317.
26. Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L: The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science 2001, 294:1731-1735.
27. Sinclair C, Mirakhur M, Kirk J, Farrell M, McQuaid S: Up-regulation of osteopontin and αβ-crystallin in the normal-appearing white matter of multiple sclerosis: an immunohistochemical study utilizing tissue microarrays. Neuropathol Appl Neurobiol 2005, 31:292-303.
28. Diaz-Sanchez M, Williams K, DeLuca GC, Esiri MM: Protein co-expression with axonal injury in multiple sclerosis plaques. Acta Neuropathol 2006, 111:289-299.
29. Selvaraju R, Bernasconi L, Losberger C, Graber P, Kadi L, Avellana-Adalid V, Picard-Riera N, Baron Van Evercooren A, Cirillo R, Kosco-Vilbois M, Feger G, Papoian R, Boschert U: Osteopontin is upregulated during in vivo demyelination and remyelination and enhances myelin formation in vitro. Mol Cell Neurosci 2004, 25:707-721.
30. Kim MD, Cho HJ, Shin T: Expression of osteopontin and its ligand, CD44, in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis. J Neuroimmunol 2004, 151:78-84.
31. Jansson M, Panoutsakopoulou V, Baker J, Klein L, Cantor H: Cutting edge: attenuated experimental autoimmune encephalomyelitis in Eta-1/osteopontin-deficient mice. J Immunol 2002, 168:2096-2099.
32. Schroeter M, Zickler P, Denhardt DT, Hartung HP, Jander S: Increased thalamic neurodegeneration following ischaemic cortical stroke in osteopontin-deficient mice. Brain 2006, 129:1426-1437.
33. Fatemi A, Wilson MA, Johnston MV: Hypoxic-ischemic encephalopathy in the term infant. Clin Perinatol 2009, 36:835-858. vii.
34. Volpe JJ, Kinney HC, Jensen FE, Rosenberg PA: The developing oligodendrocyte: key cellular target in brain injury in the premature infant. Int J Dev Neurosci 2011, 29:423-440.
35. Alvarez-Díaz A, Hilario E, de Cerio FG, Valls-i-Soler A, Alvarez-Díaz FJ: Hypoxic-ischemic injury in the immature brain-key vascular and cellular players. Neonatology 2007, 92:227-235.
36. Back SA: Perinatal white matter injury: the changing spectrum of pathology and emerging insights into pathogenetic mechanisms. Ment Retard Dev Disabil Res Rev 2006, 12:129-140.
37. Wang X, Carlsson Y, Basso E, Zhu C, Rousset CI, Rasola A, Johansson BR, Blomgren K, Mallard C, Bernardi P, Forte MA, Hagberg H: Developmental shift of cyclophilin D contribution to hypoxic-ischemic brain injury. J Neurosci 2009, 29:2588-2596.
38. Zhu C, Wang X, Xu F, Bahr BA, Shibata M, Uchiyama Y, Hagberg H, Blomgren K: The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia. Cell Death Differ 2005, 12:162-176.
39. Blaschuk KL, Frost EE, ffrench-Constant C: The regulation of proliferation and differentiation in oligodendrocyte progenitor cells by αv integrins. Development 2000, 127:1961-1969.
40. 1 -related integrin by oligodendroglia in primary culture: evidence for a functional role in myelination. J Cell Biol 1994, 124:1039-1046.
41. Relvas JB, Setzu A, Baron W, Buttery PC, LaFlamme SE, Franklin RJ, ffrench-Constant C: Expression of dominant-negative and chimeric subunits reveals an essential role for β1 integrin during myelination. Curr Biol 2001, 11:1039-1043.
42. Zhao C, Fancy SPJ, Franklin RJ, ffrench-Constant C: Up-regulation of oligodendrocyte precursor cell αV integrin and its extracellular ligands during central nervous system remyelination. J Neurosci Res 2009, 87:3447-3455.
43. Frost EE, Buttery PC, Milner R, ffrench-Constant C: Integrins mediate a neuronal survival signal for oligodendrocytes. Curr Biol 1999, 9:1251-1254.
44. Craig A, Ling Luo N, Beardsley DJ, Wingate-Pearse NL, Walker DW, Hohimer AR, Back SA: Quantitative analysis of perinatal rodent oligodendrocyte lineage progression and its correlation with human. Exp Neurol 2003, 181:231-240.
45. Marchetti G, Escuin S, van der Flier A, De Arcangelis A, Hynes RO, Georges-Labouesse E: Integrin α5β1 is necessary for regulation of radial migration of cortical neurons during mouse brain development. Eur J Neurosci 2010, 31:399-409.
46. Schmid RS, Anton ES: Role of integrins in the development of the cerebral cortex. Cereb Cortex 2003, 13:219-224.
47. Schmid RS, Shelton S, Stanco A, Yokota Y, Kreidberg JA, Anton ES: α3β1 integrin modulates neuronal migration and placement during early stages of cerebral cortical development. Development 2004, 131:6023-6031.
48. Nikonenko I, Toni N, Moosmayer M, Shigeri Y, Muller D, Sargent Jones L: Integrins are involved in synaptogenesis, cell spreading, and adhesion in the postnatal brain. Brain Res Dev Brain Res 2003, 140:185-194.
49. Einheber S, Schnapp LM, Salzer JL, Cappiello ZB, Milner TA: Regional and ultrastructural distribution of the α8 integrin subunit in developing and adult rat brain suggests a role in synaptic function. J Comp Neurol 1996, 370:105-134.
50. Hristova M, Cuthill D, Zbarsky V, Acosta-Saltos A, Wallace A, Blight K, Buckley SM, Peebles D, Heuer H, Waddington SN, Raivich G: Activation and deactivation of periventricular white matter phagocytes during postnatal mouse development. Glia 2010, 58:11-28.
51. Levy O, Matthews T, Even T: The "purse-string" technique: an arthroscopic technique for stabilization of anteroinferior instability of the shoulder with early and medium-term results. Arthroscopy 2007, 23:57-64.
52. Bhat R, Axtell R, Mitra A, Miranda M, Lock C, Tsien RW, Steinman L: Inhibitory role for GABA in autoimmune inflammation. Proc Natl Acad Sci U S A 2010, 107:2580-2585.
53. Shinohara ML, Lu L, Bu J, Werneck MB, Kobayashi KS, Glimcher LH, Cantor H: Osteopontin expression is essential for interferon-α production by plasmacytoid dendritic cells. Nat Immunol 2006, 7:498-506.
54. Massoud SN, Levy O, Copeland SA: Radiofrequency capsular shrinkage for voluntary shoulder instability. J Shoulder Elbow Surg 2007, 16:43-48.
55. Barry ST, Ludbrook SB, Murrison E, Horgan CMT: A regulated interaction between α5β1 integrin and osteopontin. Biochem Biophys Res Commun 2000, 267:764-769.
56. 5 J Biol Chem 1995, 270:26232-26238.
57. 3 in smooth muscle cell migration to osteopontin in vitro. J Clin Invest 1995, 95:713-724.
58. Kienstra KA, Freysdottir D, Gonzales NM, Hirschi KK: Murine neonatal intravascular injections: modeling newborn disease. J Am Assoc Lab Anim Sci 2007, 46:50-54.
59. Graham PL 3rd, Begg MD, Larson E, Della-Latta P, Allen A, Saiman L: Risk factors for late onset Gram-negative sepsis in low birth weight infants hospitalized in the neonatal intensive care unit. Pediatr Infect Dis J 2006, 25:113-117.
60. Chen KT, Huard RC, Della-Latta P, Saiman L: Prevalence of methicillin-sensitive and methicillin-resistant Staphylococcus aureus in pregnant women. Obstet Gynecol 2006, 108:482-487.
61. He B, Mirza M, Weber GF: An osteopontin splice variant induces anchorage independence in human breast cancer cells. Oncogene 2006, 25:2192-2202.
62. Lochhead JJ, Thorne RG: Intranasal delivery of biologics to the central nervous system. Adv Drug Deliv Rev 2012, 64:614-628.
63. Liu X: Clinical trials of intranasal delivery for treating neurological disorders-a critical review. Expert Opin Drug Deliv 2011, 8:1681-1690.
64. Born J, Lange T, Kern W, McGregor GP, Bickel U, Fehm HL: Sniffing neuropeptides: a transnasal approach to the human brain. Nat Neurosci 2002, 5:514-516.
65. van Velthoven CT, Kavelaars A, van Bel F, Heijnen CJ: Mesenchymal stem cell transplantation changes the gene expression profile of the neonatal ischemic brain. Brain Behav Immun 2011, 25:1342-1348.